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The map label for this gene is yyxA [H]

Identifier: 152975976

GI number: 152975976

Start: 2351809

End: 2353044

Strand: Reverse

Name: yyxA [H]

Synonym: Bcer98_2249

Alternate gene names: 152975976

Gene position: 2353044-2351809 (Counterclockwise)

Preceding gene: 152975977

Following gene: 152975975

Centisome position: 57.57

GC content: 38.11

Gene sequence:

>1236_bases
ATGGGATATTATGACGGACCAAATATGAACGGAGAATATGACGAAACAAAAGAAATAAGAAAAAACGGTAGTAAAAAAGG
GTATTTCTTTACCGGTTTAGTTGGAGCTGTGGTCGGAGCAGTTTCTATTAGTTTTGCAGCACCTTATATGCCATGGGCAA
AAAATAACGATGTAGCTGTTTCATCTGTATCTTCTAATTCAAACGTAGAAGGTACGGTTGTACCAGTTGTGAATAAATCG
AAAAATGAAACAGATTTACCTGGCATGATTGAAGGGGCAAAAGAAGTTGTTGTCGGTGTTATCAATATGCAAAAAACAAT
CGATCCATTTGCTATGCAGCCGATTGGTCAAGAGCAAGAAGCTGGCTTAGGATCGGGCGTTATTTATAAAAAAGCTGGGA
ATAAAGCATATGTTGTTACAAATAATCACGTAGTGGATGGAGCCAATAAACTTGCTGTTAAATTAAGCAATGGTAAAGAG
GTTGATGCAAAATTAGTTGGGAAAGATCCTTGGCTAGATTTAGCTGTTGTCGAAATCGATGGTTCCAATATTAATAAAGT
TGCTACGCTAGGGGATTCTAGCAAAATTCGTGCAGGCGAACCAGCCATCGCAATCGGGAATCCGCTAGGCTTTGATGGCA
GTGTAACAGAAGGAATTATCAGTAGTAAAGAACGTGAAATTCCAGTTGATATCGATGGTGATAAACGTCCCGATTGGAAT
GCACAAGTGATTCAAACAGATGCAGCGATTAACCCAGGAAATAGCGGCGGTGCTTTATTTAACCAAAATGGCGAAGTAAT
TGGGATTAACTCTAGTAAAATTGCACAGCAAGAAGTAGAAGGAATCGGGTTCGCCATTCCGATTAATATTGCAAAACCTG
TGATTGAATCACTTGAAAAAGATGGAACAGTGAAACGACCAGCTCTTGGCGTTGGAGTTGTTTCATTAGAAGATGTGCAA
AGATACGCTTCACAATTGAAATTACCAAAAGATATAACAAGTGGAGTTGTGTTAGGGAAAGTTTATCCAATTTCACCAGC
AGAAAAAGCTGGACTAGAGCAATATGACGTTGTTGTTGCATTAGATAACCAAAAAGTGGAGAATGCATTGCAATTCCGTA
AATATTTATACGAAAAGAAAAAAGTAGGAGATAAAATTGATGTGACATTTTATCGCAATGGTGAAAAAATGACGAAAACT
GCTACTTTAACGGATAACGCTTCGGCTAAGAATTAA

Upstream 100 bases:

>100_bases
ATAAGGACATTTTTGAATTGGATTTCACGATGAGTTCACAAGAAGGACACAAAATGTGATTATACTGAAAATACGAATTC
AGCAGAGAGGGGAAGTTAAC

Downstream 100 bases:

>100_bases
TAAAGAAAGTCTCTTTCGTATTGAAAGAGGCTTTCTTTATCGGCTATACTAAAAGAATAGGAGGGATTTAATATGACAAT
TAAAAATCCAACTCGTTCGG

Product: 2-alkenal reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MGYYDGPNMNGEYDETKEIRKNGSKKGYFFTGLVGAVVGAVSISFAAPYMPWAKNNDVAVSSVSSNSNVEGTVVPVVNKS
KNETDLPGMIEGAKEVVVGVINMQKTIDPFAMQPIGQEQEAGLGSGVIYKKAGNKAYVVTNNHVVDGANKLAVKLSNGKE
VDAKLVGKDPWLDLAVVEIDGSNINKVATLGDSSKIRAGEPAIAIGNPLGFDGSVTEGIISSKEREIPVDIDGDKRPDWN
AQVIQTDAAINPGNSGGALFNQNGEVIGINSSKIAQQEVEGIGFAIPINIAKPVIESLEKDGTVKRPALGVGVVSLEDVQ
RYASQLKLPKDITSGVVLGKVYPISPAEKAGLEQYDVVVALDNQKVENALQFRKYLYEKKKVGDKIDVTFYRNGEKMTKT
ATLTDNASAKN

Sequences:

>Translated_411_residues
MGYYDGPNMNGEYDETKEIRKNGSKKGYFFTGLVGAVVGAVSISFAAPYMPWAKNNDVAVSSVSSNSNVEGTVVPVVNKS
KNETDLPGMIEGAKEVVVGVINMQKTIDPFAMQPIGQEQEAGLGSGVIYKKAGNKAYVVTNNHVVDGANKLAVKLSNGKE
VDAKLVGKDPWLDLAVVEIDGSNINKVATLGDSSKIRAGEPAIAIGNPLGFDGSVTEGIISSKEREIPVDIDGDKRPDWN
AQVIQTDAAINPGNSGGALFNQNGEVIGINSSKIAQQEVEGIGFAIPINIAKPVIESLEKDGTVKRPALGVGVVSLEDVQ
RYASQLKLPKDITSGVVLGKVYPISPAEKAGLEQYDVVVALDNQKVENALQFRKYLYEKKKVGDKIDVTFYRNGEKMTKT
ATLTDNASAKN
>Mature_410_residues
GYYDGPNMNGEYDETKEIRKNGSKKGYFFTGLVGAVVGAVSISFAAPYMPWAKNNDVAVSSVSSNSNVEGTVVPVVNKSK
NETDLPGMIEGAKEVVVGVINMQKTIDPFAMQPIGQEQEAGLGSGVIYKKAGNKAYVVTNNHVVDGANKLAVKLSNGKEV
DAKLVGKDPWLDLAVVEIDGSNINKVATLGDSSKIRAGEPAIAIGNPLGFDGSVTEGIISSKEREIPVDIDGDKRPDWNA
QVIQTDAAINPGNSGGALFNQNGEVIGINSSKIAQQEVEGIGFAIPINIAKPVIESLEKDGTVKRPALGVGVVSLEDVQR
YASQLKLPKDITSGVVLGKVYPISPAEKAGLEQYDVVVALDNQKVENALQFRKYLYEKKKVGDKIDVTFYRNGEKMTKTA
TLTDNASAKN

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=259, Percent_Identity=37.8378378378378, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI7019477, Length=303, Percent_Identity=33.993399339934, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI22129776, Length=280, Percent_Identity=33.2142857142857, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI24308541, Length=263, Percent_Identity=32.6996197718631, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1786356, Length=276, Percent_Identity=39.4927536231884, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1789629, Length=284, Percent_Identity=37.3239436619718, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1789630, Length=287, Percent_Identity=33.1010452961672, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24646839, Length=422, Percent_Identity=30.0947867298578, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 43748; Mature: 43617

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYYDGPNMNGEYDETKEIRKNGSKKGYFFTGLVGAVVGAVSISFAAPYMPWAKNNDVAV
CCCCCCCCCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
SSVSSNSNVEGTVVPVVNKSKNETDLPGMIEGAKEVVVGVINMQKTIDPFAMQPIGQEQE
EEECCCCCCCEEEEEEECCCCCCCCCCHHHHCCHHHEEEEEHHHHHCCCHHCCCCCCHHH
AGLGSGVIYKKAGNKAYVVTNNHVVDGANKLAVKLSNGKEVDAKLVGKDPWLDLAVVEID
CCCCCCEEEEECCCEEEEEECCEEECCCCEEEEEECCCCEECEEEECCCCCCEEEEEEEC
GSNINKVATLGDSSKIRAGEPAIAIGNPLGFDGSVTEGIISSKEREIPVDIDGDKRPDWN
CCCCCEEEECCCCCCCCCCCCCEEECCCCCCCCCHHHHHHCCCCCCCCEECCCCCCCCCC
AQVIQTDAAINPGNSGGALFNQNGEVIGINSSKIAQQEVEGIGFAIPINIAKPVIESLEK
CEEEEECCCCCCCCCCCEEECCCCCEEEECCHHHHHHHHHCCCEEEEHHHHHHHHHHHHC
DGTVKRPALGVGVVSLEDVQRYASQLKLPKDITSGVVLGKVYPISPAEKAGLEQYDVVVA
CCCCCCCCCEEEEEEHHHHHHHHHHCCCCCHHHCCEEEEEEECCCCHHHCCCCEEEEEEE
LDNQKVENALQFRKYLYEKKKVGDKIDVTFYRNGEKMTKTATLTDNASAKN
ECCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEEECCCCCCCC
>Mature Secondary Structure 
GYYDGPNMNGEYDETKEIRKNGSKKGYFFTGLVGAVVGAVSISFAAPYMPWAKNNDVAV
CCCCCCCCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
SSVSSNSNVEGTVVPVVNKSKNETDLPGMIEGAKEVVVGVINMQKTIDPFAMQPIGQEQE
EEECCCCCCCEEEEEEECCCCCCCCCCHHHHCCHHHEEEEEHHHHHCCCHHCCCCCCHHH
AGLGSGVIYKKAGNKAYVVTNNHVVDGANKLAVKLSNGKEVDAKLVGKDPWLDLAVVEID
CCCCCCEEEEECCCEEEEEECCEEECCCCEEEEEECCCCEECEEEECCCCCCEEEEEEEC
GSNINKVATLGDSSKIRAGEPAIAIGNPLGFDGSVTEGIISSKEREIPVDIDGDKRPDWN
CCCCCEEEECCCCCCCCCCCCCEEECCCCCCCCCHHHHHHCCCCCCCCEECCCCCCCCCC
AQVIQTDAAINPGNSGGALFNQNGEVIGINSSKIAQQEVEGIGFAIPINIAKPVIESLEK
CEEEEECCCCCCCCCCCEEECCCCCEEEECCHHHHHHHHHCCCEEEEHHHHHHHHHHHHC
DGTVKRPALGVGVVSLEDVQRYASQLKLPKDITSGVVLGKVYPISPAEKAGLEQYDVVVA
CCCCCCCCCEEEEEEHHHHHHHHHHCCCCCHHHCCEEEEEEECCCCHHHCCCCEEEEEEE
LDNQKVENALQFRKYLYEKKKVGDKIDVTFYRNGEKMTKTATLTDNASAKN
ECCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8113162 [H]