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The map label for this gene is ydbM [H]

Identifier: 152975810

GI number: 152975810

Start: 2167518

End: 2168672

Strand: Reverse

Name: ydbM [H]

Synonym: Bcer98_2066

Alternate gene names: 152975810

Gene position: 2168672-2167518 (Counterclockwise)

Preceding gene: 152975811

Following gene: 152975809

Centisome position: 53.06

GC content: 39.48

Gene sequence:

>1155_bases
ATGACAATTTCATTTGTAGAAACAGAAGAACAATCTTTATGGATTGAAAAGATACAGAAGTTTCTTCCAAAGTTTCAGGA
AAGGGAGTGTGAACTTCGTGAATTAGGCTCTTTTCCGTTTGAGAATATAAACGAGTTAAAAGATATCGGTTATACAACTT
TAACGCTTCCGAAAGACTGCGGGGGACAAGAGATTTCGCTCTATGATTTTGTTTTATATCAAGAGAAAATTGCAGAAGGA
GATGGAGCGACTGCTTTATCAATTGGATGGCATCTTGGTATCGTGAAAGAGCTTACGGAAAATCAATCTTGGAAGCCGGA
TATGTTCGCATGGTTTTGTGAGGAAGTGAAGAAAGGGGCCCTTTTTAATCGAGCCGCAACAGAACGAAAGACAGGAAGTC
CGACACGTGGCGGGCGACCAGAAACGTTAGCGGTGAAAAAGGGTGAAAAGTGGATTATAAACGGAAGAAAGACATTTACA
ACGATGGCGCCAATGCTTGATTATTTCATTATTTCTGCAAGTATTGAAGGACGAGAGGAGATTGGAGAGTTTGTCGTTCC
AAGAGCACAAAAAGGTGTTTCCATTGAAGAAACATGGGATAGTGTTGCGATGCGGGGAACAGCGAGTCATGATCTCGTAT
TGCGAAATGTAGAAATTTCTGATAAATATTTTACGGATATAAAAGGATCGCAATCAAAACCAAAAGGAGTGGGATGGTTA
CTTCATATACCGGCATGTTATTTAGGAATTGCACAAGCTGCTCGGAACTATGCGCTCCGGTTTGCTGAATCGTATCAACC
GAATAGTTTAAAGCATCCAATCAGCTCACTGCCCAATATTAGAAGATTAGTAGGAGAGTTAGAACTTGAATTGATGCAAG
CTCGTATGTTTCTATATCAAATAGCAAAAAAGTATGATGAAGTTGATGATAAGCAGTCCTTACAAGCAGAATTAGCAGCG
GCGAAATATATTGCAACGAATGCAGCAATTTCCGTTGTTGATAAAGCGATGCGCATTGTTGGTGCGAAAAGTTTATCAGA
AAAAAATCCATTACACCGTTATTATTTAAATGTGAGGGCAGGATTACACAATCCACCAATGGATGATGTGACAATCTCAT
TGATGGCTAATTCTGCTTTTCACTCAATAGGATAA

Upstream 100 bases:

>100_bases
TTTTTTGATTATTTACATATAAGAAAAAGAAGAAAGAGTATACTTTCGCCAACGAATAGAAATTTTCGTTTCAATAACTC
GAAATAAAGGGGATAGTAAG

Downstream 100 bases:

>100_bases
GAGAAAAAATAGGCATCTAAAAAGGGGAATACATTTGTCCTTTTTAGATGCTATCTTTTATTAAGAGTGCACTTTTACAT
GAGGGATGATGGTATCATAA

Product: acyl-CoA dehydrogenase type 2

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MTISFVETEEQSLWIEKIQKFLPKFQERECELRELGSFPFENINELKDIGYTTLTLPKDCGGQEISLYDFVLYQEKIAEG
DGATALSIGWHLGIVKELTENQSWKPDMFAWFCEEVKKGALFNRAATERKTGSPTRGGRPETLAVKKGEKWIINGRKTFT
TMAPMLDYFIISASIEGREEIGEFVVPRAQKGVSIEETWDSVAMRGTASHDLVLRNVEISDKYFTDIKGSQSKPKGVGWL
LHIPACYLGIAQAARNYALRFAESYQPNSLKHPISSLPNIRRLVGELELELMQARMFLYQIAKKYDEVDDKQSLQAELAA
AKYIATNAAISVVDKAMRIVGAKSLSEKNPLHRYYLNVRAGLHNPPMDDVTISLMANSAFHSIG

Sequences:

>Translated_384_residues
MTISFVETEEQSLWIEKIQKFLPKFQERECELRELGSFPFENINELKDIGYTTLTLPKDCGGQEISLYDFVLYQEKIAEG
DGATALSIGWHLGIVKELTENQSWKPDMFAWFCEEVKKGALFNRAATERKTGSPTRGGRPETLAVKKGEKWIINGRKTFT
TMAPMLDYFIISASIEGREEIGEFVVPRAQKGVSIEETWDSVAMRGTASHDLVLRNVEISDKYFTDIKGSQSKPKGVGWL
LHIPACYLGIAQAARNYALRFAESYQPNSLKHPISSLPNIRRLVGELELELMQARMFLYQIAKKYDEVDDKQSLQAELAA
AKYIATNAAISVVDKAMRIVGAKSLSEKNPLHRYYLNVRAGLHNPPMDDVTISLMANSAFHSIG
>Mature_383_residues
TISFVETEEQSLWIEKIQKFLPKFQERECELRELGSFPFENINELKDIGYTTLTLPKDCGGQEISLYDFVLYQEKIAEGD
GATALSIGWHLGIVKELTENQSWKPDMFAWFCEEVKKGALFNRAATERKTGSPTRGGRPETLAVKKGEKWIINGRKTFTT
MAPMLDYFIISASIEGREEIGEFVVPRAQKGVSIEETWDSVAMRGTASHDLVLRNVEISDKYFTDIKGSQSKPKGVGWLL
HIPACYLGIAQAARNYALRFAESYQPNSLKHPISSLPNIRRLVGELELELMQARMFLYQIAKKYDEVDDKQSLQAELAAA
KYIATNAAISVVDKAMRIVGAKSLSEKNPLHRYYLNVRAGLHNPPMDDVTISLMANSAFHSIG

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=339, Percent_Identity=23.0088495575221, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI226958412, Length=400, Percent_Identity=23.75, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI226958414, Length=356, Percent_Identity=22.752808988764, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1786223, Length=378, Percent_Identity=20.3703703703704, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17538396, Length=329, Percent_Identity=27.355623100304, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=328, Percent_Identity=22.8658536585366, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356377, Length=334, Percent_Identity=24.251497005988, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21355753, Length=325, Percent_Identity=24.9230769230769, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646207, Length=362, Percent_Identity=22.9281767955801, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 43242; Mature: 43111

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISFVETEEQSLWIEKIQKFLPKFQERECELRELGSFPFENINELKDIGYTTLTLPKDC
CEEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHCCCEEEECCCCC
GGQEISLYDFVLYQEKIAEGDGATALSIGWHLGIVKELTENQSWKPDMFAWFCEEVKKGA
CCCEEEHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
LFNRAATERKTGSPTRGGRPETLAVKKGEKWIINGRKTFTTMAPMLDYFIISASIEGREE
HHHHHHHCCCCCCCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCHHH
IGEFVVPRAQKGVSIEETWDSVAMRGTASHDLVLRNVEISDKYFTDIKGSQSKPKGVGWL
HHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHCCCCCCCCCCCCEEE
LHIPACYLGIAQAARNYALRFAESYQPNSLKHPISSLPNIRRLVGELELELMQARMFLYQ
EEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHH
IAKKYDEVDDKQSLQAELAAAKYIATNAAISVVDKAMRIVGAKSLSEKNPLHRYYLNVRA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
GLHNPPMDDVTISLMANSAFHSIG
CCCCCCCCCEEEEEEECCHHHCCC
>Mature Secondary Structure 
TISFVETEEQSLWIEKIQKFLPKFQERECELRELGSFPFENINELKDIGYTTLTLPKDC
EEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHCCCEEEECCCCC
GGQEISLYDFVLYQEKIAEGDGATALSIGWHLGIVKELTENQSWKPDMFAWFCEEVKKGA
CCCEEEHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
LFNRAATERKTGSPTRGGRPETLAVKKGEKWIINGRKTFTTMAPMLDYFIISASIEGREE
HHHHHHHCCCCCCCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCHHH
IGEFVVPRAQKGVSIEETWDSVAMRGTASHDLVLRNVEISDKYFTDIKGSQSKPKGVGWL
HHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHCCCCCCCCCCCCEEE
LHIPACYLGIAQAARNYALRFAESYQPNSLKHPISSLPNIRRLVGELELELMQARMFLYQ
EEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHH
IAKKYDEVDDKQSLQAELAAAKYIATNAAISVVDKAMRIVGAKSLSEKNPLHRYYLNVRA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
GLHNPPMDDVTISLMANSAFHSIG
CCCCCCCCCEEEEEEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]