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The map label for this gene is pagR [H]

Identifier: 152975671

GI number: 152975671

Start: 2019836

End: 2020132

Strand: Reverse

Name: pagR [H]

Synonym: Bcer98_1906

Alternate gene names: 152975671

Gene position: 2020132-2019836 (Counterclockwise)

Preceding gene: 152975672

Following gene: 152975669

Centisome position: 49.43

GC content: 32.32

Gene sequence:

>297_bases
ATGGCAATGAAAAGTAAAGAGATAAAAACACAAATTACAGAAGAAGATGTAGATATTTTAAAAGTGATGGCACATCCAGT
ACGATTACAAATTGTTAACGAGTTAAAAAATAGAAAAACTTGTAACGTATCACAGCTAACCGAAATTTTAGAAATCCCGC
AATCCACTGTATCTCAACACTTATCGAAAATGAAAGGAAAAGTGCTACGTTCCGAACGAAAAGGATTGGAAATGTATTAT
TACATTAATAATGCAAAGGCAAGTGAGATTGCTGGCATTTTAGGCTGTGTAAATTAA

Upstream 100 bases:

>100_bases
TTTTATATAGAATAACAATAAATAAGTTACAGGGGTGGCATTCACTTTCTCTGAATGCCTTTTATAGAAAAAGAAATGCA
ACAAAAAAGGAGAGATTCTC

Downstream 100 bases:

>100_bases
TAAAAATATAAGAAGATTACAAAAAACATCTCTACATCATAATGTGGGGATGTTTTTTTATGTGAATTCATGATAAAAAA
TAGCTTTCATGAGTTATATT

Product: regulatory protein ArsR

Products: NA

Alternate protein names: Protective antigen repressor [H]

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MAMKSKEIKTQITEEDVDILKVMAHPVRLQIVNELKNRKTCNVSQLTEILEIPQSTVSQHLSKMKGKVLRSERKGLEMYY
YINNAKASEIAGILGCVN

Sequences:

>Translated_98_residues
MAMKSKEIKTQITEEDVDILKVMAHPVRLQIVNELKNRKTCNVSQLTEILEIPQSTVSQHLSKMKGKVLRSERKGLEMYY
YINNAKASEIAGILGCVN
>Mature_97_residues
AMKSKEIKTQITEEDVDILKVMAHPVRLQIVNELKNRKTCNVSQLTEILEIPQSTVSQHLSKMKGKVLRSERKGLEMYYY
INNAKASEIAGILGCVN

Specific function: Represses the expression of the pagA and atxA genes [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11119; Mature: 10988

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMKSKEIKTQITEEDVDILKVMAHPVRLQIVNELKNRKTCNVSQLTEILEIPQSTVSQH
CCCCCHHHHHHHCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHH
LSKMKGKVLRSERKGLEMYYYINNAKASEIAGILGCVN
HHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure 
AMKSKEIKTQITEEDVDILKVMAHPVRLQIVNELKNRKTCNVSQLTEILEIPQSTVSQH
CCCCHHHHHHHCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHH
LSKMKGKVLRSERKGLEMYYYINNAKASEIAGILGCVN
HHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10419943; 10515943; 12004073; 12067380; 10475965 [H]