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The map label for this gene is tenA [H]

Identifier: 152975658

GI number: 152975658

Start: 2007441

End: 2008124

Strand: Reverse

Name: tenA [H]

Synonym: Bcer98_1892

Alternate gene names: 152975658

Gene position: 2008124-2007441 (Counterclockwise)

Preceding gene: 152975659

Following gene: 152975657

Centisome position: 49.13

GC content: 39.04

Gene sequence:

>684_bases
ATGTCATTTTCACAGTTATTACGTCAAGAAGTTGCTCCGATTTGGCAAGCGAGTTTTGAGCATCCATTTATTAAAGAACT
AGGTGAGGGAACACTAGATTTAGCTAGCTTTCGTTACTACGTTTTACAAGATTCCTACTATTTGAGTCACTTCGCTAGAG
TACAAACATTAGGGGCAGCGAAGGCGATCGAATTGAAAACGACAGCTCGCATGGCACATCATGCACAAAATACATATGAA
GCAGAATTGTCATTGCATGAAAATTTTGCGGAAAAATTAGGAATCACTGAAGAAGAAAAAGCATCCTTTATTCCAGCACC
GACAGCTTATGCATATACATCCCATATGTATCGCGCTGCTTATGAAGGGCATTTAGGTGATATTATTGCATCCATTTTAC
CGTGTTATTGGCTATATTATGAAATTGGCGAGCGTCTTAAAGAGTGTAAGCCAGAAGAACCGATTTACCAAGCATGGATT
TCAGCATATGGTTCGGATTGGTTCCGCACATTAGTAGAAGAACAAATTATGCGATTAGATCAAATTGCGGAAACAGTAAC
AGAGTCGGATCGTAAACGTATGAAACAGCATTTTATCATTAGTAGTCAATATGAATATTCGTTCTGGGAGATGGCTTATA
CGTTAGAGAAATGGCCCGTTGAAGAAAAAATAGCAACCCGGTAG

Upstream 100 bases:

>100_bases
GCCACTTTCTTTACCTACTAAGGAAGTGGCTTTTATTTTGTACATTTCTATTTTTTCGTTAGATGTTAGCTGAGTGTAGC
ATATATGAGGAGGGATATAA

Downstream 100 bases:

>100_bases
ATATTCATTTTATTTCTTCATTTTTCATAATATATTATGAAAAAATTATATAATTAAAAGAGAAATAGGAAAGATAAAGA
GGAGGTAGAACCCTCCTCCT

Product: TenA family transcription regulator

Products: NA

Alternate protein names: Thiaminase II; Transcriptional activator tenA [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSFSQLLRQEVAPIWQASFEHPFIKELGEGTLDLASFRYYVLQDSYYLSHFARVQTLGAAKAIELKTTARMAHHAQNTYE
AELSLHENFAEKLGITEEEKASFIPAPTAYAYTSHMYRAAYEGHLGDIIASILPCYWLYYEIGERLKECKPEEPIYQAWI
SAYGSDWFRTLVEEQIMRLDQIAETVTESDRKRMKQHFIISSQYEYSFWEMAYTLEKWPVEEKIATR

Sequences:

>Translated_227_residues
MSFSQLLRQEVAPIWQASFEHPFIKELGEGTLDLASFRYYVLQDSYYLSHFARVQTLGAAKAIELKTTARMAHHAQNTYE
AELSLHENFAEKLGITEEEKASFIPAPTAYAYTSHMYRAAYEGHLGDIIASILPCYWLYYEIGERLKECKPEEPIYQAWI
SAYGSDWFRTLVEEQIMRLDQIAETVTESDRKRMKQHFIISSQYEYSFWEMAYTLEKWPVEEKIATR
>Mature_226_residues
SFSQLLRQEVAPIWQASFEHPFIKELGEGTLDLASFRYYVLQDSYYLSHFARVQTLGAAKAIELKTTARMAHHAQNTYEA
ELSLHENFAEKLGITEEEKASFIPAPTAYAYTSHMYRAAYEGHLGDIIASILPCYWLYYEIGERLKECKPEEPIYQAWIS
AYGSDWFRTLVEEQIMRLDQIAETVTESDRKRMKQHFIISSQYEYSFWEMAYTLEKWPVEEKIATR

Specific function: Stimulates the production of several extracellular degradative enzymes at the transcriptional level, probably by interfering with degS and degU, which are required for this effect. Is not an essential protein, but affects the sporulation frequency [H]

COG id: COG0819

COG function: function code K; Putative transcription activator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiaminase-2 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324517, Length=207, Percent_Identity=26.0869565217391, Blast_Score=79, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6325378, Length=210, Percent_Identity=25.2380952380952, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324997, Length=206, Percent_Identity=20.873786407767, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016084
- InterPro:   IPR004305 [H]

Pfam domain/function: PF03070 TENA_THI-4 [H]

EC number: =3.5.99.2 [H]

Molecular weight: Translated: 26616; Mature: 26485

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSQLLRQEVAPIWQASFEHPFIKELGEGTLDLASFRYYVLQDSYYLSHFARVQTLGAA
CCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCH
KAIELKTTARMAHHAQNTYEAELSLHENFAEKLGITEEEKASFIPAPTAYAYTSHMYRAA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHH
YEGHLGDIIASILPCYWLYYEIGERLKECKPEEPIYQAWISAYGSDWFRTLVEEQIMRLD
HHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHH
QIAETVTESDRKRMKQHFIISSQYEYSFWEMAYTLEKWPVEEKIATR
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHCCC
>Mature Secondary Structure 
SFSQLLRQEVAPIWQASFEHPFIKELGEGTLDLASFRYYVLQDSYYLSHFARVQTLGAA
CHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCH
KAIELKTTARMAHHAQNTYEAELSLHENFAEKLGITEEEKASFIPAPTAYAYTSHMYRAA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHH
YEGHLGDIIASILPCYWLYYEIGERLKECKPEEPIYQAWISAYGSDWFRTLVEEQIMRLD
HHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHH
QIAETVTESDRKRMKQHFIISSQYEYSFWEMAYTLEKWPVEEKIATR
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1898926; 9384377 [H]