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The map label for this gene is pbuX [H]

Identifier: 152975103

GI number: 152975103

Start: 1410532

End: 1411854

Strand: Direct

Name: pbuX [H]

Synonym: Bcer98_1303

Alternate gene names: 152975103

Gene position: 1410532-1411854 (Clockwise)

Preceding gene: 152975102

Following gene: 152975105

Centisome position: 34.51

GC content: 38.32

Gene sequence:

>1323_bases
ATGAAGCAACATCCATTTAAAATTGCTTCTCTCGGTATGCAACATATGCTTGCGATGTACGCTGGGGCTATTATTGTTCC
ACTTATTGTTGGCGGAGGACTTGGACTAAGTCAGAAAGAATTAACTTATTTAGTTTCTATTGACTTATTAATGTGCGGCG
TTGCTACAATCTTACAAGCATTATCAAATCGTTTTTTTGGAATTGGTCTCCCGGTTGTACTTGGATGTACATTTACAGCG
GTTGGACCGATGATTGCAATCGGTAAGCAGTATGGTGTTTCTTCTATATATGGAGCAATTATTGCTGCTGGATTGTTCGT
TGTTATTTTTGCGAAACTATTTGGCAAACTAGTAAAGTTATTTCCACCTGTTGTAACAGGTTCTGTTGTTACGGTAATTG
GGGTTACGTTAGTTCCAGCAGCCATTAATGATATGGCTGGTGGTGCAGGGAGTAAAGACTTTGGAAGTTTGGAAAATTTA
GCGTTAGCATTTGGTGTGCTACTATTTATCGTTATTATGTATCGTTTCTTTGATGGATTTATTCGTTCCATTTCTATTTT
ACTTGGTCTTTTATTTGGAACGATTATGGCAGCTTTAATGGGGAAAGTAAGCCTGCAGGCTGTTTGGGAAGCGGATTGGT
TTCATGGAATACAGCCTTTTTATTTCGGAACACCTACATTTGCATTCACTCCAATGATTACGATGATTCTCGTTGCTTGC
GTAGGGATAGTGGAAGCAACTGGGGTATATTTTGCTTTATCTGATATATGTAATAAAAAGATTGGCGAAAAAGATTTAAC
AAAAGGGTATCGTGCTGAAGGATTGGCGATGATTTTAGGTGGAATCTTTAATGCCTTTCCGTATACGACTTACTCACAAA
ACGTCGGTCTTGTGCAATTAACAGGTGTGCGAAATCGCATCATCATTTATGTATGTGGTGGTATGTTAATTGTGCTCGGA
TTTATCCCTAAAATTGCAGCCATTACAACGATTATTCCAAAGCCAGTGCTTGGCGGTGCAATGCTCGCAATGTTTGGGAT
GGTGATGGCATATGGAATTAAAATGTTAAGCAATGTTGATTTTGGAAAACAAGAAAACTTACTTATCGTGGCATGTTCTG
TTGGAATTGGCCTTGGCGTAACAGTCGTTCCAACGTTATTCTCACAATTTCCAGAAAGTATTCGTATTTTAACAGACAAT
GGTATTGTACTTGGAAGTGCTTCAGCGGTTATTTTAAATATTGTATTTCATATGATTCCGGAGCGCAGAGCGAAAACAAA
AGAAGAGCAAGTTTCAATGAAAAGTGCTGTCACAGAAATGTAA

Upstream 100 bases:

>100_bases
GTGAGAGAGGCGTTCGCGTAGAATCATTGGCAGAAATTGCATCGCTTGAAGATGGTACGGTTACCTTTGTTCAACATGAA
ACTGCGGAGGTGAGATAGCA

Downstream 100 bases:

>100_bases
ATCAACAAAAGCAAGGTTCTCATGAAGAGACCTTGCTTTTGTTTTTTAAAGGCATCATTTTTCCATACGTACCAAGGCGC
CAAATGTATTCAAGTGGGCC

Product: uracil-xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKQHPFKIASLGMQHMLAMYAGAIIVPLIVGGGLGLSQKELTYLVSIDLLMCGVATILQALSNRFFGIGLPVVLGCTFTA
VGPMIAIGKQYGVSSIYGAIIAAGLFVVIFAKLFGKLVKLFPPVVTGSVVTVIGVTLVPAAINDMAGGAGSKDFGSLENL
ALAFGVLLFIVIMYRFFDGFIRSISILLGLLFGTIMAALMGKVSLQAVWEADWFHGIQPFYFGTPTFAFTPMITMILVAC
VGIVEATGVYFALSDICNKKIGEKDLTKGYRAEGLAMILGGIFNAFPYTTYSQNVGLVQLTGVRNRIIIYVCGGMLIVLG
FIPKIAAITTIIPKPVLGGAMLAMFGMVMAYGIKMLSNVDFGKQENLLIVACSVGIGLGVTVVPTLFSQFPESIRILTDN
GIVLGSASAVILNIVFHMIPERRAKTKEEQVSMKSAVTEM

Sequences:

>Translated_440_residues
MKQHPFKIASLGMQHMLAMYAGAIIVPLIVGGGLGLSQKELTYLVSIDLLMCGVATILQALSNRFFGIGLPVVLGCTFTA
VGPMIAIGKQYGVSSIYGAIIAAGLFVVIFAKLFGKLVKLFPPVVTGSVVTVIGVTLVPAAINDMAGGAGSKDFGSLENL
ALAFGVLLFIVIMYRFFDGFIRSISILLGLLFGTIMAALMGKVSLQAVWEADWFHGIQPFYFGTPTFAFTPMITMILVAC
VGIVEATGVYFALSDICNKKIGEKDLTKGYRAEGLAMILGGIFNAFPYTTYSQNVGLVQLTGVRNRIIIYVCGGMLIVLG
FIPKIAAITTIIPKPVLGGAMLAMFGMVMAYGIKMLSNVDFGKQENLLIVACSVGIGLGVTVVPTLFSQFPESIRILTDN
GIVLGSASAVILNIVFHMIPERRAKTKEEQVSMKSAVTEM
>Mature_440_residues
MKQHPFKIASLGMQHMLAMYAGAIIVPLIVGGGLGLSQKELTYLVSIDLLMCGVATILQALSNRFFGIGLPVVLGCTFTA
VGPMIAIGKQYGVSSIYGAIIAAGLFVVIFAKLFGKLVKLFPPVVTGSVVTVIGVTLVPAAINDMAGGAGSKDFGSLENL
ALAFGVLLFIVIMYRFFDGFIRSISILLGLLFGTIMAALMGKVSLQAVWEADWFHGIQPFYFGTPTFAFTPMITMILVAC
VGIVEATGVYFALSDICNKKIGEKDLTKGYRAEGLAMILGGIFNAFPYTTYSQNVGLVQLTGVRNRIIIYVCGGMLIVLG
FIPKIAAITTIIPKPVLGGAMLAMFGMVMAYGIKMLSNVDFGKQENLLIVACSVGIGLGVTVVPTLFSQFPESIRILTDN
GIVLGSASAVILNIVFHMIPERRAKTKEEQVSMKSAVTEM

Specific function: Transport of xanthine in the cell [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=231, Percent_Identity=29.004329004329, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI40316845, Length=231, Percent_Identity=29.004329004329, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI44680143, Length=226, Percent_Identity=26.5486725663717, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI44680145, Length=226, Percent_Identity=26.5486725663717, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI87082181, Length=435, Percent_Identity=41.8390804597701, Blast_Score=338, Evalue=4e-94,
Organism=Escherichia coli, GI1790087, Length=427, Percent_Identity=30.2107728337237, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI87082178, Length=434, Percent_Identity=31.7972350230415, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI87081818, Length=401, Percent_Identity=29.1770573566085, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788843, Length=380, Percent_Identity=28.1578947368421, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17558856, Length=219, Percent_Identity=29.2237442922374, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17542262, Length=443, Percent_Identity=25.2821670428894, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17541904, Length=419, Percent_Identity=23.8663484486874, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17542260, Length=190, Percent_Identity=26.3157894736842, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71993493, Length=190, Percent_Identity=25.7894736842105, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356175, Length=432, Percent_Identity=25.6944444444444, Blast_Score=90, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46805; Mature: 46805

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9098051; 9384377 [H]