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The map label for this gene is aroB

Identifier: 152975040

GI number: 152975040

Start: 1350061

End: 1351170

Strand: Direct

Name: aroB

Synonym: Bcer98_1240

Alternate gene names: 152975040

Gene position: 1350061-1351170 (Clockwise)

Preceding gene: 152975039

Following gene: 152975041

Centisome position: 33.03

GC content: 38.2

Gene sequence:

>1110_bases
ATGGAAAGTATACACATTCAAACAACATCCAAAAAATATGATGTATATGTTGGCAAACATGTCCTATCCTCTTTAACAGA
GGTTGTTCAACGTATGAAACCAGCTGTTTCAAATGTTATGATCATTTCTGATGAATCTGTTGCAACCTTGCATTTACAAA
AAGTAAAAGAGGCTTTGCAAATAAAGCAAGATGTGTTTTCATTTGTTATTCCAAGTGGAGAAAAAGAAAAGTCATTTGAA
AATTTCTATGCAGTCCATACAGCGGCACTTGAGAACAAGCTCGATCGTAATTCATTAATAATTGCACTAGGTGGCGGAAT
GATTGGCGATTTAGCAGGATTTGTAGCAGCTACATTTATGCGGGGGATTCGCTTTGTTCAAGTACCCACAACACTGTTGG
CACATGATAGTGCAGTGGGCGGGAAGGTGGCCATTAACCATCCTTTAGGGAAAAACATGATCGGGGCGTTTCATCAGCCA
GAAGCGGTGTTATACCATACGCCATTTCTAGATTCATTACCTGAAAAAGAATGGCGCTCTGGCTTTGCTGAAGTAATCAA
ACACGCTTTAATCGGAGATGTAGAATTATATCATTGGTTAAAAAACAATGTGACAACATTGGCGGATTTACGAGATGATA
AATTAGTTTATGTATTAAAACGTGCAATCCCTGTCAAAGCGAAGATTGTAGCGCAAGATGAGACAGAAAAAGGGGTGCGT
GCACATTTGAACTTTGGGCATACATTAGGACATGCCTTAGAAAAAGAATCGGGATATGGCAATATCACGCATGGTGACGG
TGTTGCAATCGGCATGTTATTTGCCATATTTTTAAGTGAACAAATGTATAAGATTGACCTCAGGTATAAAGAATTAAAAC
AGTGGTTTTTGCAGTATGGTTACCCGAGCATACCAAGGCATTTGAAGGTGGATCGTCTTGTAAATGTTATGAAACAAGAT
AAAAAAGCAAATGCTGGAACAATTCGTATGGTACTTATGCAGGAATATGGGGGCGTACATGTCGTATCTATTTCAGATAA
GACCGTTCACACTTCATTAGAAGCATTTCAAAAAGATATGGTACTAGGTGAAGAAATGAATTTTGAATGA

Upstream 100 bases:

>100_bases
GGGAGCTAGCTACAGCTTTAGTGGAGCAATTTGGAGCAGATCGAATGGATTGTATTCGTGAAAATATTGAGCGACATAAT
GAATACGCGAGGGAATTTTA

Downstream 100 bases:

>100_bases
TGGTGACGGTTGGAAAAGAGTATGTAGTATAAGAAACGGCTTCTTATATTGCCGCTGATTAAACAAAATGACTGGGGGAA
GAAAAATGAAAGTGAAAGAG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MESIHIQTTSKKYDVYVGKHVLSSLTEVVQRMKPAVSNVMIISDESVATLHLQKVKEALQIKQDVFSFVIPSGEKEKSFE
NFYAVHTAALENKLDRNSLIIALGGGMIGDLAGFVAATFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQP
EAVLYHTPFLDSLPEKEWRSGFAEVIKHALIGDVELYHWLKNNVTTLADLRDDKLVYVLKRAIPVKAKIVAQDETEKGVR
AHLNFGHTLGHALEKESGYGNITHGDGVAIGMLFAIFLSEQMYKIDLRYKELKQWFLQYGYPSIPRHLKVDRLVNVMKQD
KKANAGTIRMVLMQEYGGVHVVSISDKTVHTSLEAFQKDMVLGEEMNFE

Sequences:

>Translated_369_residues
MESIHIQTTSKKYDVYVGKHVLSSLTEVVQRMKPAVSNVMIISDESVATLHLQKVKEALQIKQDVFSFVIPSGEKEKSFE
NFYAVHTAALENKLDRNSLIIALGGGMIGDLAGFVAATFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQP
EAVLYHTPFLDSLPEKEWRSGFAEVIKHALIGDVELYHWLKNNVTTLADLRDDKLVYVLKRAIPVKAKIVAQDETEKGVR
AHLNFGHTLGHALEKESGYGNITHGDGVAIGMLFAIFLSEQMYKIDLRYKELKQWFLQYGYPSIPRHLKVDRLVNVMKQD
KKANAGTIRMVLMQEYGGVHVVSISDKTVHTSLEAFQKDMVLGEEMNFE
>Mature_369_residues
MESIHIQTTSKKYDVYVGKHVLSSLTEVVQRMKPAVSNVMIISDESVATLHLQKVKEALQIKQDVFSFVIPSGEKEKSFE
NFYAVHTAALENKLDRNSLIIALGGGMIGDLAGFVAATFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQP
EAVLYHTPFLDSLPEKEWRSGFAEVIKHALIGDVELYHWLKNNVTTLADLRDDKLVYVLKRAIPVKAKIVAQDETEKGVR
AHLNFGHTLGHALEKESGYGNITHGDGVAIGMLFAIFLSEQMYKIDLRYKELKQWFLQYGYPSIPRHLKVDRLVNVMKQD
KKANAGTIRMVLMQEYGGVHVVSISDKTVHTSLEAFQKDMVLGEEMNFE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=347, Percent_Identity=40.3458213256484, Blast_Score=243, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6320332, Length=371, Percent_Identity=31.5363881401617, Blast_Score=170, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_BACCN (A7GN54)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001374557.1
- ProteinModelPortal:   A7GN54
- SMR:   A7GN54
- STRING:   A7GN54
- EnsemblBacteria:   EBBACT00000036570
- GeneID:   5345175
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_1240
- eggNOG:   COG0337
- GeneTree:   EBGT00050000002325
- HOGENOM:   HBG632303
- OMA:   YINEFAL
- ProtClustDB:   PRK00002
- BioCyc:   BCER315749:BCER98_1240-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 41301; Mature: 41301

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESIHIQTTSKKYDVYVGKHVLSSLTEVVQRMKPAVSNVMIISDESVATLHLQKVKEALQ
CCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHH
IKQDVFSFVIPSGEKEKSFENFYAVHTAALENKLDRNSLIIALGGGMIGDLAGFVAATFM
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHH
RGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPEAVLYHTPFLDSLPEKEWRS
HCCEEEEECHHHHHCCCCCCCEEEEECCCCCHHHCCCCCCCEEEEECCCHHCCCCHHHHH
GFAEVIKHALIGDVELYHWLKNNVTTLADLRDDKLVYVLKRAIPVKAKIVAQDETEKGVR
HHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCE
AHLNFGHTLGHALEKESGYGNITHGDGVAIGMLFAIFLSEQMYKIDLRYKELKQWFLQYG
ECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCHHHEEECHHHHHHHHHHHCC
YPSIPRHLKVDRLVNVMKQDKKANAGTIRMVLMQEYGGVHVVSISDKTVHTSLEAFQKDM
CCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHH
VLGEEMNFE
HCCCCCCCC
>Mature Secondary Structure
MESIHIQTTSKKYDVYVGKHVLSSLTEVVQRMKPAVSNVMIISDESVATLHLQKVKEALQ
CCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHH
IKQDVFSFVIPSGEKEKSFENFYAVHTAALENKLDRNSLIIALGGGMIGDLAGFVAATFM
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHH
RGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPEAVLYHTPFLDSLPEKEWRS
HCCEEEEECHHHHHCCCCCCCEEEEECCCCCHHHCCCCCCCEEEEECCCHHCCCCHHHHH
GFAEVIKHALIGDVELYHWLKNNVTTLADLRDDKLVYVLKRAIPVKAKIVAQDETEKGVR
HHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCE
AHLNFGHTLGHALEKESGYGNITHGDGVAIGMLFAIFLSEQMYKIDLRYKELKQWFLQYG
ECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCHHHEEECHHHHHHHHHHHCC
YPSIPRHLKVDRLVNVMKQDKKANAGTIRMVLMQEYGGVHVVSISDKTVHTSLEAFQKDM
CCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHH
VLGEEMNFE
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA