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The map label for this gene is recS [H]

Identifier: 152975008

GI number: 152975008

Start: 1322199

End: 1323746

Strand: Direct

Name: recS [H]

Synonym: Bcer98_1208

Alternate gene names: 152975008

Gene position: 1322199-1323746 (Clockwise)

Preceding gene: 152975007

Following gene: 152975009

Centisome position: 32.35

GC content: 34.69

Gene sequence:

>1548_bases
ATGAAACTTGAAGAGCATTTAAATAAATGGTTTGGATACAAGGAGTTTCGCCAAGGACAGAAAGAGGTTATTACAGACTT
ACTGCAAGGGAAAGATGTCGTAGCAATGCTTCCAACAGGACAAGGAAAGTCTATGTGCTATCAACTTCCGGGTTTGTTGC
AAGGAGGAACGGTATTGATTGTCTCTCCGCTTCTATCTTTAATGGAAGATCAAGTTACACAGCTGAAATATGTTGTGAAA
AATCGTGTCATTGCATTTAATAGTTTTCGTACATTAAGTGAGAAAAGAAAAGCGATTAAGCAGTTAGCATGGTATAAATT
TGTCTTCGTTTCACCTGAAATGTTGCAATCTGAATTATTAATGAAAGAATTGAAAAAAATTCCTATTTCTTTGTTTGTTG
TAGATGAGGCTCACTGCATTTCACAATGGGGATATGATTTTCGAACAGATTATAAAAAATTGGATCAAGTAATTATGCGC
ATTGGCCGTCCCCCAGTACTAGCATTAACGGCGACGGCTACAAAGGAAGTATTGCAAGATATTATAGTAAGTTTAGGCTT
GAAGAATGTCTCCCAGCATGTGTATTCAATTGATCGACCGAATATCGCTATAGAAGTACAGTTTTTAGAAACGATAGAGG
AAAAAAAAGAAGCGCTTCTTTCGCATGTTTCTTACTTACAAGGGCCAGGAATTATTTATTGCTCCAGCAGAGCTTGGACA
GAGCGGTTAACGGAGTATTTAAGGAGTAAAGGAATAATAGATGTTGCTTTTTATCATGGTGGAATGGATCATGAAGAAAG
GATGTTAATTCAGCAGCAATTTATGAATGACCAACTGCAACTTGTTATTTGCACAAGTGCTTTTGGAATGGGAGTTAACA
AACCGAATACAAGGTATATTATTCATTTTCATTATCCTACGAATATTGCTTCCTATTTGCAAGAAATAGGAAGAGCAGGT
CGTGATGGAGAGGCGAGTATAGCGATTTTATTATGTAGTCCACTCGATCATGATTTACCTATTTCTATTATTGAAGATGA
ATTGCCTAATAAAAAGCAAATTCAATTTTTATTTGCTTTATTACAAGAAAAATTACTTCAAACGAAAAGATTACCGATAG
AAGATGTGGCAGAAATTTGTTATCATACTGCAGGATTAAATGAACAACATTGGCGTTTTCTTAAGTATCATTTAGAAAAA
ATGGAAATCGTACAACAAAATATGCTTATATTAGAAGACTTGTCAGATGAAACGATGCAAAAATTAATATTAGAGGTGGA
GAAACGCCTTTATAATAAATATAATCAATTAGAAAAGATGAAATCGTGGTTACAAATTCAAGGTTGTAAACGAGAACAAT
TATTACAGCTGTTCGGGTATGAAAAGGAAGATAAGATAAAAAATTGTTGTGACTACTGCGGTATTATAAAAGAAGAGTAT
AAAAAAAGACGAGCAAGGCAGTCAGTTTTCGACTATAATTGGGAAACAGAGTTACAATTGCTCTTTGGTATGGGAGAACG
GAGGAATGATGAATATTCAAAGGCGTAG

Upstream 100 bases:

>100_bases
ACGTTACAAACAAGGAAGCTACGTGCATTAAAACAAGCGGTAGGAGAGGAGATTTCTTATTTTGAAATTCGCCTAGTATT
AGCACAACTGGAGGGAACAA

Downstream 100 bases:

>100_bases
CGTTGAAGATATGAGTCCGAAAGAGATACGACTTAACCTCTATATCACACAACTGATTATAATAAGTATTGGATGTTTGC
TAGCATATATATTATTTCCA

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: Recombination protein S [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MKLEEHLNKWFGYKEFRQGQKEVITDLLQGKDVVAMLPTGQGKSMCYQLPGLLQGGTVLIVSPLLSLMEDQVTQLKYVVK
NRVIAFNSFRTLSEKRKAIKQLAWYKFVFVSPEMLQSELLMKELKKIPISLFVVDEAHCISQWGYDFRTDYKKLDQVIMR
IGRPPVLALTATATKEVLQDIIVSLGLKNVSQHVYSIDRPNIAIEVQFLETIEEKKEALLSHVSYLQGPGIIYCSSRAWT
ERLTEYLRSKGIIDVAFYHGGMDHEERMLIQQQFMNDQLQLVICTSAFGMGVNKPNTRYIIHFHYPTNIASYLQEIGRAG
RDGEASIAILLCSPLDHDLPISIIEDELPNKKQIQFLFALLQEKLLQTKRLPIEDVAEICYHTAGLNEQHWRFLKYHLEK
MEIVQQNMLILEDLSDETMQKLILEVEKRLYNKYNQLEKMKSWLQIQGCKREQLLQLFGYEKEDKIKNCCDYCGIIKEEY
KKRRARQSVFDYNWETELQLLFGMGERRNDEYSKA

Sequences:

>Translated_515_residues
MKLEEHLNKWFGYKEFRQGQKEVITDLLQGKDVVAMLPTGQGKSMCYQLPGLLQGGTVLIVSPLLSLMEDQVTQLKYVVK
NRVIAFNSFRTLSEKRKAIKQLAWYKFVFVSPEMLQSELLMKELKKIPISLFVVDEAHCISQWGYDFRTDYKKLDQVIMR
IGRPPVLALTATATKEVLQDIIVSLGLKNVSQHVYSIDRPNIAIEVQFLETIEEKKEALLSHVSYLQGPGIIYCSSRAWT
ERLTEYLRSKGIIDVAFYHGGMDHEERMLIQQQFMNDQLQLVICTSAFGMGVNKPNTRYIIHFHYPTNIASYLQEIGRAG
RDGEASIAILLCSPLDHDLPISIIEDELPNKKQIQFLFALLQEKLLQTKRLPIEDVAEICYHTAGLNEQHWRFLKYHLEK
MEIVQQNMLILEDLSDETMQKLILEVEKRLYNKYNQLEKMKSWLQIQGCKREQLLQLFGYEKEDKIKNCCDYCGIIKEEY
KKRRARQSVFDYNWETELQLLFGMGERRNDEYSKA
>Mature_515_residues
MKLEEHLNKWFGYKEFRQGQKEVITDLLQGKDVVAMLPTGQGKSMCYQLPGLLQGGTVLIVSPLLSLMEDQVTQLKYVVK
NRVIAFNSFRTLSEKRKAIKQLAWYKFVFVSPEMLQSELLMKELKKIPISLFVVDEAHCISQWGYDFRTDYKKLDQVIMR
IGRPPVLALTATATKEVLQDIIVSLGLKNVSQHVYSIDRPNIAIEVQFLETIEEKKEALLSHVSYLQGPGIIYCSSRAWT
ERLTEYLRSKGIIDVAFYHGGMDHEERMLIQQQFMNDQLQLVICTSAFGMGVNKPNTRYIIHFHYPTNIASYLQEIGRAG
RDGEASIAILLCSPLDHDLPISIIEDELPNKKQIQFLFALLQEKLLQTKRLPIEDVAEICYHTAGLNEQHWRFLKYHLEK
MEIVQQNMLILEDLSDETMQKLILEVEKRLYNKYNQLEKMKSWLQIQGCKREQLLQLFGYEKEDKIKNCCDYCGIIKEEY
KKRRARQSVFDYNWETELQLLFGMGERRNDEYSKA

Specific function: Probable DNA helicase. Required in synaptic and/or post- synaptic stages of recombination. Probably has overlapping function with recQ (AC O34748). It probably acts to help generate ss-DNA from ds-DNA breaks [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI110735439, Length=341, Percent_Identity=40.1759530791789, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI169218196, Length=341, Percent_Identity=40.1759530791789, Blast_Score=235, Evalue=6e-62,
Organism=Homo sapiens, GI51242947, Length=367, Percent_Identity=37.3297002724796, Blast_Score=231, Evalue=9e-61,
Organism=Homo sapiens, GI51242943, Length=367, Percent_Identity=37.3297002724796, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI148612816, Length=357, Percent_Identity=37.8151260504202, Blast_Score=229, Evalue=6e-60,
Organism=Homo sapiens, GI4557365, Length=346, Percent_Identity=36.7052023121387, Blast_Score=210, Evalue=3e-54,
Organism=Homo sapiens, GI14591902, Length=344, Percent_Identity=34.8837209302326, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI14591904, Length=344, Percent_Identity=34.8837209302326, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI284005309, Length=359, Percent_Identity=32.8690807799443, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI21071032, Length=337, Percent_Identity=24.3323442136499, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI20149629, Length=346, Percent_Identity=24.8554913294798, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI45446747, Length=340, Percent_Identity=21.7647058823529, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI45446743, Length=340, Percent_Identity=21.7647058823529, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI7661920, Length=356, Percent_Identity=22.1910112359551, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI13514831, Length=356, Percent_Identity=23.0337078651685, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI222352149, Length=349, Percent_Identity=22.9226361031519, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI48994977, Length=335, Percent_Identity=43.5820895522388, Blast_Score=271, Evalue=8e-74,
Organism=Escherichia coli, GI1787605, Length=344, Percent_Identity=21.8023255813953, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32564293, Length=348, Percent_Identity=39.9425287356322, Blast_Score=242, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI71987997, Length=336, Percent_Identity=36.6071428571429, Blast_Score=215, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI71987993, Length=336, Percent_Identity=36.6071428571429, Blast_Score=215, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI25145561, Length=348, Percent_Identity=34.1954022988506, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17552866, Length=367, Percent_Identity=33.7874659400545, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17555296, Length=332, Percent_Identity=23.7951807228916, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71987143, Length=360, Percent_Identity=23.6111111111111, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71995724, Length=355, Percent_Identity=22.8169014084507, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17507121, Length=355, Percent_Identity=22.5352112676056, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115533224, Length=323, Percent_Identity=23.8390092879257, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71999646, Length=364, Percent_Identity=23.0769230769231, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17537549, Length=346, Percent_Identity=20.2312138728324, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71999644, Length=364, Percent_Identity=23.0769230769231, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=341, Percent_Identity=39.2961876832845, Blast_Score=230, Evalue=5e-61,
Organism=Saccharomyces cerevisiae, GI6324217, Length=336, Percent_Identity=26.1904761904762, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6320224, Length=356, Percent_Identity=23.0337078651685, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6319714, Length=352, Percent_Identity=21.875, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6321360, Length=328, Percent_Identity=25.9146341463415, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320449, Length=338, Percent_Identity=22.189349112426, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320041, Length=341, Percent_Identity=23.4604105571848, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324778, Length=345, Percent_Identity=21.4492753623188, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24646066, Length=347, Percent_Identity=36.3112391930836, Blast_Score=222, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24664226, Length=347, Percent_Identity=36.0230547550432, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI62472181, Length=347, Percent_Identity=36.0230547550432, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24664230, Length=347, Percent_Identity=36.0230547550432, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI21358123, Length=347, Percent_Identity=35.1585014409222, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI28575014, Length=397, Percent_Identity=22.6700251889169, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24645031, Length=351, Percent_Identity=21.9373219373219, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355075, Length=344, Percent_Identity=21.8023255813953, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17977678, Length=347, Percent_Identity=23.6311239193084, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281361218, Length=333, Percent_Identity=24.024024024024, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644481, Length=333, Percent_Identity=24.024024024024, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644487, Length=333, Percent_Identity=24.024024024024, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45551833, Length=333, Percent_Identity=24.024024024024, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644485, Length=333, Percent_Identity=24.024024024024, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644483, Length=333, Percent_Identity=24.024024024024, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644479, Length=333, Percent_Identity=24.024024024024, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18857967, Length=397, Percent_Identity=22.4181360201511, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24666101, Length=342, Percent_Identity=23.0994152046784, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR002464
- InterPro:   IPR004589
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 60079; Mature: 60079

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00690 DEAH_ATP_HELICASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEEHLNKWFGYKEFRQGQKEVITDLLQGKDVVAMLPTGQGKSMCYQLPGLLQGGTVLI
CCHHHHHHHHCCHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHCCCCCCCCHHHH
VSPLLSLMEDQVTQLKYVVKNRVIAFNSFRTLSEKRKAIKQLAWYKFVFVSPEMLQSELL
HHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHH
MKELKKIPISLFVVDEAHCISQWGYDFRTDYKKLDQVIMRIGRPPVLALTATATKEVLQD
HHHHHHCCEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHH
IIVSLGLKNVSQHVYSIDRPNIAIEVQFLETIEEKKEALLSHVSYLQGPGIIYCSSRAWT
HHHHHCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHH
ERLTEYLRSKGIIDVAFYHGGMDHEERMLIQQQFMNDQLQLVICTSAFGMGVNKPNTRYI
HHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEHHHCCCCCCCCCEEE
IHFHYPTNIASYLQEIGRAGRDGEASIAILLCSPLDHDLPISIIEDELPNKKQIQFLFAL
EEEECCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHH
LQEKLLQTKRLPIEDVAEICYHTAGLNEQHWRFLKYHLEKMEIVQQNMLILEDLSDETMQ
HHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KLILEVEKRLYNKYNQLEKMKSWLQIQGCKREQLLQLFGYEKEDKIKNCCDYCGIIKEEY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KKRRARQSVFDYNWETELQLLFGMGERRNDEYSKA
HHHHHHHHHHCCCCCHHHHHEECCCCCCCCCCCCC
>Mature Secondary Structure
MKLEEHLNKWFGYKEFRQGQKEVITDLLQGKDVVAMLPTGQGKSMCYQLPGLLQGGTVLI
CCHHHHHHHHCCHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHCCCCCCCCHHHH
VSPLLSLMEDQVTQLKYVVKNRVIAFNSFRTLSEKRKAIKQLAWYKFVFVSPEMLQSELL
HHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHH
MKELKKIPISLFVVDEAHCISQWGYDFRTDYKKLDQVIMRIGRPPVLALTATATKEVLQD
HHHHHHCCEEEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHH
IIVSLGLKNVSQHVYSIDRPNIAIEVQFLETIEEKKEALLSHVSYLQGPGIIYCSSRAWT
HHHHHCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHH
ERLTEYLRSKGIIDVAFYHGGMDHEERMLIQQQFMNDQLQLVICTSAFGMGVNKPNTRYI
HHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEHHHCCCCCCCCCEEE
IHFHYPTNIASYLQEIGRAGRDGEASIAILLCSPLDHDLPISIIEDELPNKKQIQFLFAL
EEEECCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHH
LQEKLLQTKRLPIEDVAEICYHTAGLNEQHWRFLKYHLEKMEIVQQNMLILEDLSDETMQ
HHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
KLILEVEKRLYNKYNQLEKMKSWLQIQGCKREQLLQLFGYEKEDKIKNCCDYCGIIKEEY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
KKRRARQSVFDYNWETELQLLFGMGERRNDEYSKA
HHHHHHHHHHCCCCCHHHHHEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377; 9642195 [H]