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The map label for this gene is resD [H]

Identifier: 152975000

GI number: 152975000

Start: 1314438

End: 1315154

Strand: Direct

Name: resD [H]

Synonym: Bcer98_1200

Alternate gene names: 152975000

Gene position: 1314438-1315154 (Clockwise)

Preceding gene: 152974999

Following gene: 152975001

Centisome position: 32.16

GC content: 36.26

Gene sequence:

>717_bases
ATGGAAAACGAACCAAGAATTTTAGTTGTAGATGATGAGGATCGAATTCGTCGTTTATTAAAAATGTATTTAGAAAGAGA
GAACTACGTAATTGATGAAGCTGACAATGGTGATACAGCTTTAGAAAAGGCACTGCAAAATGATTATGATTTAATTCTAT
TAGATATTATGATGCCTGGAAAAGATGGAATAGAAGTTTGTAAAGGAATTCGTGAGAAAAAAGCAACACCAGTTATTATG
CTGACAGCTAAAGGTGAGGAAGTAAATAGAGTACAAGGATTTGAAGTTGGATCTGATGATTATATTGTAAAACCATTTAG
TCCGCGCGAAGTTGTTCTTCGTGTGAAAGCTGTATTGCGCCGTTCTGTATCGACAACATTCTTTACACAAGATACAACCA
CGAAAGATGTAATTGTATTCCCGCATCTAACAATTGATAATGATGCTCATCGCATTACAGCAGATGGACAGGAAGTAAAT
TTAACACCGAAAGAGTATGAATTGTTACTATTCTTAGCGAAGTCTCCAGATAAAGTGTTTGATCGTGAACAATTATTAAA
AGAAGTGTGGCAATATGAATTCTTTGGAGACTTACGTACAGTGGATACACATGTGAAGCGTTTACGCGAGAAGCTCAGTA
AAAAATCACCTAATGCAGCGAAGATGATTGTAACTGTATGGGGCGTGGGTTATAAGTTTGAGGTTGTGAACGACTGA

Upstream 100 bases:

>100_bases
ATGATTCCTTATGAAATGAGAATAAGCATAGGATTATATTGGAGAAAGGTAGGTGTGAACCGCAGCGGTCATTTTGAAAC
ATAAGCCGCAGCGGGTAGCA

Downstream 100 bases:

>100_bases
TGCTTTGGCGGAGTGTAGTAGGTAAGTTATGGATGACCATATTACTGCTTGTTTCGTTTGTTCTTGGCTTTGTAGCGATT
TTACTTTCCCAGTTTTTTAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MENEPRILVVDDEDRIRRLLKMYLERENYVIDEADNGDTALEKALQNDYDLILLDIMMPGKDGIEVCKGIREKKATPVIM
LTAKGEEVNRVQGFEVGSDDYIVKPFSPREVVLRVKAVLRRSVSTTFFTQDTTTKDVIVFPHLTIDNDAHRITADGQEVN
LTPKEYELLLFLAKSPDKVFDREQLLKEVWQYEFFGDLRTVDTHVKRLREKLSKKSPNAAKMIVTVWGVGYKFEVVND

Sequences:

>Translated_238_residues
MENEPRILVVDDEDRIRRLLKMYLERENYVIDEADNGDTALEKALQNDYDLILLDIMMPGKDGIEVCKGIREKKATPVIM
LTAKGEEVNRVQGFEVGSDDYIVKPFSPREVVLRVKAVLRRSVSTTFFTQDTTTKDVIVFPHLTIDNDAHRITADGQEVN
LTPKEYELLLFLAKSPDKVFDREQLLKEVWQYEFFGDLRTVDTHVKRLREKLSKKSPNAAKMIVTVWGVGYKFEVVND
>Mature_238_residues
MENEPRILVVDDEDRIRRLLKMYLERENYVIDEADNGDTALEKALQNDYDLILLDIMMPGKDGIEVCKGIREKKATPVIM
LTAKGEEVNRVQGFEVGSDDYIVKPFSPREVVLRVKAVLRRSVSTTFFTQDTTTKDVIVFPHLTIDNDAHRITADGQEVN
LTPKEYELLLFLAKSPDKVFDREQLLKEVWQYEFFGDLRTVDTHVKRLREKLSKKSPNAAKMIVTVWGVGYKFEVVND

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=42.5531914893617, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=41.5584415584416, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=36.7965367965368, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=34.1880341880342, Blast_Score=154, Evalue=3e-39,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=36.3636363636364, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=37.280701754386, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=32.1739130434783, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=34.3612334801762, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=37.1681415929204, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=33.920704845815, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=30.5676855895196, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=29.2576419213974, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=26.8398268398268, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=39.6551724137931, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788191, Length=109, Percent_Identity=34.8623853211009, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789149, Length=189, Percent_Identity=30.6878306878307, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=33.6134453781513, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788713, Length=102, Percent_Identity=36.2745098039216, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27469; Mature: 27469

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENEPRILVVDDEDRIRRLLKMYLERENYVIDEADNGDTALEKALQNDYDLILLDIMMPG
CCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCEEEEEEECCC
KDGIEVCKGIREKKATPVIMLTAKGEEVNRVQGFEVGSDDYIVKPFSPREVVLRVKAVLR
CCHHHHHHHHHHHCCCCEEEEEECCCHHHHEECEEECCCCEEECCCCHHHHHHHHHHHHH
RSVSTTFFTQDTTTKDVIVFPHLTIDNDAHRITADGQEVNLTPKEYELLLFLAKSPDKVF
HHCCCEEEECCCCCCEEEEEEEEEECCCCCEEEECCCEEECCCCCEEEEEEEECCCHHHC
DREQLLKEVWQYEFFGDLRTVDTHVKRLREKLSKKSPNAAKMIVTVWGVGYKFEVVND
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHEEEEEEECCCEEEEEECC
>Mature Secondary Structure
MENEPRILVVDDEDRIRRLLKMYLERENYVIDEADNGDTALEKALQNDYDLILLDIMMPG
CCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCCCCEEEEEEECCC
KDGIEVCKGIREKKATPVIMLTAKGEEVNRVQGFEVGSDDYIVKPFSPREVVLRVKAVLR
CCHHHHHHHHHHHCCCCEEEEEECCCHHHHEECEEECCCCEEECCCCHHHHHHHHHHHHH
RSVSTTFFTQDTTTKDVIVFPHLTIDNDAHRITADGQEVNLTPKEYELLLFLAKSPDKVF
HHCCCEEEECCCCCCEEEEEEEEEECCCCCEEEECCCEEECCCCCEEEEEEEECCCHHHC
DREQLLKEVWQYEFFGDLRTVDTHVKRLREKLSKKSPNAAKMIVTVWGVGYKFEVVND
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHEEEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]