Click here to switch to the map view.

The map label for this gene is yisZ [H]

Identifier: 152974948

GI number: 152974948

Start: 1256250

End: 1256843

Strand: Direct

Name: yisZ [H]

Synonym: Bcer98_1145

Alternate gene names: 152974948

Gene position: 1256250-1256843 (Clockwise)

Preceding gene: 152974947

Following gene: 152974949

Centisome position: 30.74

GC content: 39.06

Gene sequence:

>594_bases
ATGGACACAAATATTACGTGGCATACAGCTTCTGTTTCGAAAGAGGAGAGAAGAAAGAGGAATGGGCACCATAGTTTTGT
CATTTGGTTTACGGGGCTATCAGCTTCAGGAAAGTCAACGGTAGCAAATGCAGTTGCTAGAAAATTATTTGATAGAAACA
TAGGGAATTATGTATTGGATGGGGATAATATTCGGTACGGTTTGAATAAAGATTTAAGTTTTTCTGAAAGAGATCGCGCA
GAAAATATTCGCCGTATTGGTGAGGTTTCAAAATTATTTGTTGACCAAGGAACGATTGTGCTTACAGCTTTTATCTCACC
TTTTCGAGCAGATCGCCAGCAAGTGCGAGCTATTTTTGAGAAAGATGAATTTATCGAAGTGTTTGTGAAATGTCCAATCG
AAGAGTGTGAGAAACGAGATCCGAAAGGGTTATATGAGAAAGCGAGACAAGGGGAGATTAAGCTGTTTACGGGCATTGAT
TCTCCATACGAAGAACCGGAAAAAGCGGAATTAACTGTGGAAACAAACCGTTATTCCATTGAAGAGTGTGCGGAACAAAT
CATTCATTATTTACAAGAACGTAGCTTCATATAG

Upstream 100 bases:

>100_bases
ATGGTGACGTTCCGCCAAGTACGTTTAGCCGGAAGGAAGTCATTGAAGTATTAATTCGTGGTTTACAAAAAGCACGGTAA
CAGAATAAGGAGAGAATAGC

Downstream 100 bases:

>100_bases
GGGGATAGATTATGAGTTATGAAAAAGTATGGGCAAGCAATGAGAAATTAAATAGGACAGAGAAAAAGAAACTAGAGAAA
GATGGTTTGGAGATTTTTAA

Product: adenylyl-sulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MDTNITWHTASVSKEERRKRNGHHSFVIWFTGLSASGKSTVANAVARKLFDRNIGNYVLDGDNIRYGLNKDLSFSERDRA
ENIRRIGEVSKLFVDQGTIVLTAFISPFRADRQQVRAIFEKDEFIEVFVKCPIEECEKRDPKGLYEKARQGEIKLFTGID
SPYEEPEKAELTVETNRYSIEECAEQIIHYLQERSFI

Sequences:

>Translated_197_residues
MDTNITWHTASVSKEERRKRNGHHSFVIWFTGLSASGKSTVANAVARKLFDRNIGNYVLDGDNIRYGLNKDLSFSERDRA
ENIRRIGEVSKLFVDQGTIVLTAFISPFRADRQQVRAIFEKDEFIEVFVKCPIEECEKRDPKGLYEKARQGEIKLFTGID
SPYEEPEKAELTVETNRYSIEECAEQIIHYLQERSFI
>Mature_197_residues
MDTNITWHTASVSKEERRKRNGHHSFVIWFTGLSASGKSTVANAVARKLFDRNIGNYVLDGDNIRYGLNKDLSFSERDRA
ENIRRIGEVSKLFVDQGTIVLTAFISPFRADRQQVRAIFEKDEFIEVFVKCPIEECEKRDPKGLYEKARQGEIKLFTGID
SPYEEPEKAELTVETNRYSIEECAEQIIHYLQERSFI

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=201, Percent_Identity=49.2537313432836, Blast_Score=201, Evalue=4e-52,
Organism=Homo sapiens, GI62912492, Length=201, Percent_Identity=46.7661691542289, Blast_Score=192, Evalue=1e-49,
Organism=Homo sapiens, GI34447231, Length=201, Percent_Identity=46.7661691542289, Blast_Score=192, Evalue=1e-49,
Organism=Escherichia coli, GI1789107, Length=196, Percent_Identity=51.0204081632653, Blast_Score=212, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17542422, Length=201, Percent_Identity=48.7562189054726, Blast_Score=197, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6322852, Length=193, Percent_Identity=54.9222797927461, Blast_Score=215, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24667032, Length=202, Percent_Identity=45.5445544554455, Blast_Score=179, Evalue=8e-46,
Organism=Drosophila melanogaster, GI24667028, Length=202, Percent_Identity=45.5445544554455, Blast_Score=179, Evalue=8e-46,
Organism=Drosophila melanogaster, GI24667036, Length=202, Percent_Identity=45.5445544554455, Blast_Score=179, Evalue=8e-46,
Organism=Drosophila melanogaster, GI116007838, Length=202, Percent_Identity=45.5445544554455, Blast_Score=179, Evalue=9e-46,
Organism=Drosophila melanogaster, GI24667044, Length=202, Percent_Identity=45.5445544554455, Blast_Score=179, Evalue=9e-46,
Organism=Drosophila melanogaster, GI24667040, Length=202, Percent_Identity=45.5445544554455, Blast_Score=179, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 22816; Mature: 22816

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTNITWHTASVSKEERRKRNGHHSFVIWFTGLSASGKSTVANAVARKLFDRNIGNYVLD
CCCCEEEEECCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEC
GDNIRYGLNKDLSFSERDRAENIRRIGEVSKLFVDQGTIVLTAFISPFRADRQQVRAIFE
CCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCHHHHHHHHHHHHHH
KDEFIEVFVKCPIEECEKRDPKGLYEKARQGEIKLFTGIDSPYEEPEKAELTVETNRYSI
HHHHHHHHHHCCHHHHCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECCCCCH
EECAEQIIHYLQERSFI
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDTNITWHTASVSKEERRKRNGHHSFVIWFTGLSASGKSTVANAVARKLFDRNIGNYVLD
CCCCEEEEECCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEC
GDNIRYGLNKDLSFSERDRAENIRRIGEVSKLFVDQGTIVLTAFISPFRADRQQVRAIFE
CCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCHHHHHHHHHHHHHH
KDEFIEVFVKCPIEECEKRDPKGLYEKARQGEIKLFTGIDSPYEEPEKAELTVETNRYSI
HHHHHHHHHHCCHHHHCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECCCCCH
EECAEQIIHYLQERSFI
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]