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The map label for this gene is nrdF [H]

Identifier: 152974880

GI number: 152974880

Start: 1189403

End: 1190371

Strand: Direct

Name: nrdF [H]

Synonym: Bcer98_1076

Alternate gene names: 152974880

Gene position: 1189403-1190371 (Clockwise)

Preceding gene: 152974879

Following gene: 152974881

Centisome position: 29.1

GC content: 35.81

Gene sequence:

>969_bases
ATGCGTGCGGTAAACTGGAATAAAAAAGAAGACGATTTTAGTTTAATGTTTTGGAAGCAAAACATCGCTCAGTTTTGGAC
AGAAGAAGAAATCGCAGTATCTTCTGACAAAAATACTTGGGTGCAATTATCAAAAGAAGAACAAACGACGTATAAGCGTG
TATTAGGTGGCTTAACACTTTTAGATACAAAACAAGGTGGCGAAGGGATGCCACTTGTGCTTGTACATATCGAGAATTTA
CAAGCGAAAAGTGTGTTAGCTTTCATGGGCGCTATGGAAGAAGTGCATGCAAAGAGTTACAGTCATATCTTTACGACACT
TGCAACAGAAGAAGAAATTGATGAGATTTTCGATTGGGTGGATCAGCATCCATTACTTGAGAAAAAAGCTGGTATTATTA
CAGGATACTATCGCAAGTTATTAAAGCCACAAGTAACGAAAAAAGAGTTATACATGGCAATGGTAGCGAGTGTATTCTTA
GAAAGTTATTTATTCTATAGTGGTTTCTTCTATCCTCTATATTTAGCAGGACAAGGGAAATTAACTGCAAGTGGTGAAAT
TATTAATCTAATCATTCGTGATGAAAGTATTCACGGCGTATTCGTTGGTCTTTTAGCACAGCAAATCTTCGCTGAACTGT
CTGCAGAAGAACAAGAAGACGTGCAAAAGGAAACACAAGATTTATTGATGGAACTGTATGAAATTGAAACGGCATATACA
GAAGAAATTTATGCGTCTATTGGTCTTGTCGGAGAAGTAAATCGTTTTGTTCGTTACAATGCGAATAAAGGGCTTATGAA
CTTAGGATTAGAACCACGCTTTGAAGAAGAAGAAATTAACCCAATTGTTTTAAATGGTTTACGTACGGATACGAAAAACC
ATGATTTCTTCTCTGTAAAAGGGAATGGCTATGTAAAAGCAACGAATGTTGAAAAATTATCGGATGATGATTTTGTATTT
GATTTTTAA

Upstream 100 bases:

>100_bases
CCTGCTCATGCTTAGTTATAAATTTTTAGGTTCTGATAGACTGTGATTAGGAAGTATGAGTTTAGAAAGGATTTCATTAT
AAAAAAGAAGGGGCGATTCA

Downstream 100 bases:

>100_bases
TAGATGACTGAGGAAACAGGAGGCAAAAGCCTCCTGTTTTTGTTTTTTACCATATTGCTCATATTATTTCATTTACCCAA
TTATCAGTAATGATTAGGTT

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MRAVNWNKKEDDFSLMFWKQNIAQFWTEEEIAVSSDKNTWVQLSKEEQTTYKRVLGGLTLLDTKQGGEGMPLVLVHIENL
QAKSVLAFMGAMEEVHAKSYSHIFTTLATEEEIDEIFDWVDQHPLLEKKAGIITGYYRKLLKPQVTKKELYMAMVASVFL
ESYLFYSGFFYPLYLAGQGKLTASGEIINLIIRDESIHGVFVGLLAQQIFAELSAEEQEDVQKETQDLLMELYEIETAYT
EEIYASIGLVGEVNRFVRYNANKGLMNLGLEPRFEEEEINPIVLNGLRTDTKNHDFFSVKGNGYVKATNVEKLSDDDFVF
DF

Sequences:

>Translated_322_residues
MRAVNWNKKEDDFSLMFWKQNIAQFWTEEEIAVSSDKNTWVQLSKEEQTTYKRVLGGLTLLDTKQGGEGMPLVLVHIENL
QAKSVLAFMGAMEEVHAKSYSHIFTTLATEEEIDEIFDWVDQHPLLEKKAGIITGYYRKLLKPQVTKKELYMAMVASVFL
ESYLFYSGFFYPLYLAGQGKLTASGEIINLIIRDESIHGVFVGLLAQQIFAELSAEEQEDVQKETQDLLMELYEIETAYT
EEIYASIGLVGEVNRFVRYNANKGLMNLGLEPRFEEEEINPIVLNGLRTDTKNHDFFSVKGNGYVKATNVEKLSDDDFVF
DF
>Mature_322_residues
MRAVNWNKKEDDFSLMFWKQNIAQFWTEEEIAVSSDKNTWVQLSKEEQTTYKRVLGGLTLLDTKQGGEGMPLVLVHIENL
QAKSVLAFMGAMEEVHAKSYSHIFTTLATEEEIDEIFDWVDQHPLLEKKAGIITGYYRKLLKPQVTKKELYMAMVASVFL
ESYLFYSGFFYPLYLAGQGKLTASGEIINLIIRDESIHGVFVGLLAQQIFAELSAEEQEDVQKETQDLLMELYEIETAYT
EEIYASIGLVGEVNRFVRYNANKGLMNLGLEPRFEEEEINPIVLNGLRTDTKNHDFFSVKGNGYVKATNVEKLSDDDFVF
DF

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Escherichia coli, GI1789031, Length=323, Percent_Identity=41.4860681114551, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1788567, Length=306, Percent_Identity=25.4901960784314, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17551968, Length=298, Percent_Identity=22.8187919463087, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 36904; Mature: 36904

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS00368 RIBORED_SMALL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVNWNKKEDDFSLMFWKQNIAQFWTEEEIAVSSDKNTWVQLSKEEQTTYKRVLGGLTL
CCCCCCCCCCCCEEEEEHHHHHHHHCCCCCEEEECCCCCEEEECCHHHHHHHHHHCCCEE
LDTKQGGEGMPLVLVHIENLQAKSVLAFMGAMEEVHAKSYSHIFTTLATEEEIDEIFDWV
EECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DQHPLLEKKAGIITGYYRKLLKPQVTKKELYMAMVASVFLESYLFYSGFFYPLYLAGQGK
HCCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
LTASGEIINLIIRDESIHGVFVGLLAQQIFAELSAEEQEDVQKETQDLLMELYEIETAYT
EEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
EEIYASIGLVGEVNRFVRYNANKGLMNLGLEPRFEEEEINPIVLNGLRTDTKNHDFFSVK
HHHHHHHCHHHHHHHHEEECCCCCCEECCCCCCCCCCCCCEEEEECEECCCCCCCEEEEC
GNGYVKATNVEKLSDDDFVFDF
CCCEEEECCCCCCCCCCEEECC
>Mature Secondary Structure
MRAVNWNKKEDDFSLMFWKQNIAQFWTEEEIAVSSDKNTWVQLSKEEQTTYKRVLGGLTL
CCCCCCCCCCCCEEEEEHHHHHHHHCCCCCEEEECCCCCEEEECCHHHHHHHHHHCCCEE
LDTKQGGEGMPLVLVHIENLQAKSVLAFMGAMEEVHAKSYSHIFTTLATEEEIDEIFDWV
EECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DQHPLLEKKAGIITGYYRKLLKPQVTKKELYMAMVASVFLESYLFYSGFFYPLYLAGQGK
HCCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
LTASGEIINLIIRDESIHGVFVGLLAQQIFAELSAEEQEDVQKETQDLLMELYEIETAYT
EEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
EEIYASIGLVGEVNRFVRYNANKGLMNLGLEPRFEEEEINPIVLNGLRTDTKNHDFFSVK
HHHHHHHCHHHHHHHHEEECCCCCCEECCCCCCCCCCCCCEEEEECEECCCCCCCEEEEC
GNGYVKATNVEKLSDDDFVFDF
CCCEEEECCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969495; 9384377 [H]