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The map label for this gene is ina [H]

Identifier: 152974809

GI number: 152974809

Start: 1118701

End: 1121088

Strand: Direct

Name: ina [H]

Synonym: Bcer98_1005

Alternate gene names: 152974809

Gene position: 1118701-1121088 (Clockwise)

Preceding gene: 152974806

Following gene: 152974810

Centisome position: 27.37

GC content: 39.74

Gene sequence:

>2388_bases
ATGAAAAAGAAACCATTTAAAGTGCTATCAGCACTTGCGGTAGCGGCTGTTCTTGGAGGCGCATTTAGCTTTGGAAGTCC
GGCTGTTCAGGCAGAAACATCTGCAAAGGCAACAGCGACGAGTCCAATTGATGATCATTTGATTCCAGAAGAGCGCTTAG
CAAATGCACTTAAGAAGCGCGGGGTGATTAACGAAAAGGCGTCCGATGAAGAGACAAAGAAAGCGGTCGAGAAGTATGTC
GAGAAAAAGAAAGGTGATAAGCCTGGGAAAGATGAGATGGTTGGGGATCAAGTAACGAAAGAGGCATCTGAATTTCTGAA
GAAGGTGAAAGATGCAAAAACAGATACAAAAGAGAAAGGAAAAGAACCAGCAAGTGGACAGACAGAGGGAACTGTTCCAG
CAAAGAGCGCTTTAAATGGTAAAGTACCAACAACTCCTGCAAAAGCAAAAAAGTATAACGGAGAGGTTCGTAAAGATAAA
GTACTTGTGTTGCTTGTTGAATATGATGATTTCAAGCATAACAATATCGAACAAGAACCTGGGTATATGTATTCTGATGA
TTTTAATCAGGAACATTATGAAAAAATGTTATTCGGTGATGAACCATTTACGCTACATGATGGAAGTAAAATTGAAACAT
TTAAGCAGTATTATGAAGAACAATCTGGCGGTAGCTATACAGTAGATGGTACAGTGTCAAAGTGGTTAACCGTTCCAGGC
AAAGCAGCTGATTATGGTGCGGATGCTGGAGAAGGGCATGATAATAAAGGACCATTAGGACCGCGTGATTTAATAAAAGA
TGCATTAAAAGCAGCAGTAGAGAGTGGAATCGATTTATCGGAGTTCGATCAATTTGATCAATATGATATAGATGGTGACG
GAAATAAAAATGAACCAGATGGCTTAGTTGATCATTTAATGGTTATTCACGCTGGTGTTGGACAAGAAGCTGGTGGTGGT
AAATTAGGTGATGATGCAATTTGGTCACATCGCTGGACAATTGGTCAAAAACCATTTCCAATTGATGGGACAACAGCGAA
AGTTCCATATTGGGACGGGAAAATGGCTGCATTCGATTACACAATTGAGCCAGAGGATGGCGCAGTTGGTGTCTTCGCAC
ATGAATATGGTCATGATTTAGGGCTTCCAGATGAGTATGATACAAAATATTCTGGCGGCGGTGAACCAGTTCAATCATGG
TCTATTATGAGCGGGGGTAGTTGGGCAGGTAAAATTGCTGGAACGACGCCAACAAGTTTCTCTCCGCAAAATAAAGAGTT
TTTCCAAAAAACAATGGGGGGGAATTGGGCAAATATTGTAGAAATAGATTATGAGAAATTAAATCGAGGCATTGGTTATG
CAACATATTTAGATCAAAGTGTTACAAAATCAAATCGACCAGGCTTAATTCGTGTCAACTTACCGGACAAGGATGTAAAA
GGAATTGAGCCTGCCTTTGGACAGAAGTACTACTATAGTACAAAAGGTGACGATCTTCACACGACTTTAGAAACACCTTT
ATTTGATTTAACAAGTGCAACGAATGCAACATTTGATTTTAAATCACTGTATGAAATTGAAACAGGGTATGATTTCTTAG
AAGTACATGCGGTAACAGAAGATGGTACAAAAACATTAATTGATACAATTGGTAATAAAGATGTAAAAGATGGGGCAGAT
ACAACTTTAGGAGAATGGGTGGACAAGTCTTATGATTTAAGCCAGTTCAAAGGTAAAAAAGTGAAGCTTGTCTTTGAATA
TGTAACAGACGGCGGTCTTGCATTAAATGGCTTTACGCTTGATAATGCATCATTAACAGTAGACGGTAACGTTGTATTTT
CTGATGATGCAGAAGGAGAGACGCAGTTTAAATTAAATGGTTTTGTCGTTTCAAATGGAATTGAGAAGAAGAGCCATAAC
TATTATGTAGAGTGGAGAAATTATGCAGGTGCCGACGAAGCCTTAAAATATGCTCGTGGTCCGGTATATAACACAGGTAT
GGTTGTCTGGTATGCGGATGCAAGCTATACAGATAACTGGGTTGGGGTTCATCCGGGACATGGTTTCCTTGGAGTAGTTG
ATTCCCATCCTGAAGCCATTGCAGGCACTTTAAATGGTAAGCCAACATTTAAAGATAGCACACGTTATCAAATTGCAGAT
GCAGCATTCTCTTTCGATCAAACACCAGCTTGGAAAGTTGTATCACCAACTCGTGGAACGTTTGAATATAACGGGTTACC
TGGCGTTGCGAAATTTGATGATTCAAAAGTTTACATCAATAATCAAATTCCAGATGCAGGGCGCATTTTACCGAAGCTTG
GTTTGAAATTTGAAGTAGTTGGTCAAGCTGATGATAAATCAGCAGGTGCAGTTCGTTTATATCGATAA

Upstream 100 bases:

>100_bases
TTAAAAAAATTACATAATATTACTAAATATTGAAAATTAATTGAAAATTTAATAAAATTTATGTTGAAATATATATTTTA
TTAGGGGAGGAAAACTGGGG

Downstream 100 bases:

>100_bases
TAGGAAAAAGCTGTTGAAAGATTGCCTTTCAACAGCTTTTTTTATAGACAAAGAGTTATACAGACGCAGAAAACTTAGAT
ATAATGAAACTCTACAAATA

Product: peptidase M6 immune inhibitor A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 795; Mature: 795

Protein sequence:

>795_residues
MKKKPFKVLSALAVAAVLGGAFSFGSPAVQAETSAKATATSPIDDHLIPEERLANALKKRGVINEKASDEETKKAVEKYV
EKKKGDKPGKDEMVGDQVTKEASEFLKKVKDAKTDTKEKGKEPASGQTEGTVPAKSALNGKVPTTPAKAKKYNGEVRKDK
VLVLLVEYDDFKHNNIEQEPGYMYSDDFNQEHYEKMLFGDEPFTLHDGSKIETFKQYYEEQSGGSYTVDGTVSKWLTVPG
KAADYGADAGEGHDNKGPLGPRDLIKDALKAAVESGIDLSEFDQFDQYDIDGDGNKNEPDGLVDHLMVIHAGVGQEAGGG
KLGDDAIWSHRWTIGQKPFPIDGTTAKVPYWDGKMAAFDYTIEPEDGAVGVFAHEYGHDLGLPDEYDTKYSGGGEPVQSW
SIMSGGSWAGKIAGTTPTSFSPQNKEFFQKTMGGNWANIVEIDYEKLNRGIGYATYLDQSVTKSNRPGLIRVNLPDKDVK
GIEPAFGQKYYYSTKGDDLHTTLETPLFDLTSATNATFDFKSLYEIETGYDFLEVHAVTEDGTKTLIDTIGNKDVKDGAD
TTLGEWVDKSYDLSQFKGKKVKLVFEYVTDGGLALNGFTLDNASLTVDGNVVFSDDAEGETQFKLNGFVVSNGIEKKSHN
YYVEWRNYAGADEALKYARGPVYNTGMVVWYADASYTDNWVGVHPGHGFLGVVDSHPEAIAGTLNGKPTFKDSTRYQIAD
AAFSFDQTPAWKVVSPTRGTFEYNGLPGVAKFDDSKVYINNQIPDAGRILPKLGLKFEVVGQADDKSAGAVRLYR

Sequences:

>Translated_795_residues
MKKKPFKVLSALAVAAVLGGAFSFGSPAVQAETSAKATATSPIDDHLIPEERLANALKKRGVINEKASDEETKKAVEKYV
EKKKGDKPGKDEMVGDQVTKEASEFLKKVKDAKTDTKEKGKEPASGQTEGTVPAKSALNGKVPTTPAKAKKYNGEVRKDK
VLVLLVEYDDFKHNNIEQEPGYMYSDDFNQEHYEKMLFGDEPFTLHDGSKIETFKQYYEEQSGGSYTVDGTVSKWLTVPG
KAADYGADAGEGHDNKGPLGPRDLIKDALKAAVESGIDLSEFDQFDQYDIDGDGNKNEPDGLVDHLMVIHAGVGQEAGGG
KLGDDAIWSHRWTIGQKPFPIDGTTAKVPYWDGKMAAFDYTIEPEDGAVGVFAHEYGHDLGLPDEYDTKYSGGGEPVQSW
SIMSGGSWAGKIAGTTPTSFSPQNKEFFQKTMGGNWANIVEIDYEKLNRGIGYATYLDQSVTKSNRPGLIRVNLPDKDVK
GIEPAFGQKYYYSTKGDDLHTTLETPLFDLTSATNATFDFKSLYEIETGYDFLEVHAVTEDGTKTLIDTIGNKDVKDGAD
TTLGEWVDKSYDLSQFKGKKVKLVFEYVTDGGLALNGFTLDNASLTVDGNVVFSDDAEGETQFKLNGFVVSNGIEKKSHN
YYVEWRNYAGADEALKYARGPVYNTGMVVWYADASYTDNWVGVHPGHGFLGVVDSHPEAIAGTLNGKPTFKDSTRYQIAD
AAFSFDQTPAWKVVSPTRGTFEYNGLPGVAKFDDSKVYINNQIPDAGRILPKLGLKFEVVGQADDKSAGAVRLYR
>Mature_795_residues
MKKKPFKVLSALAVAAVLGGAFSFGSPAVQAETSAKATATSPIDDHLIPEERLANALKKRGVINEKASDEETKKAVEKYV
EKKKGDKPGKDEMVGDQVTKEASEFLKKVKDAKTDTKEKGKEPASGQTEGTVPAKSALNGKVPTTPAKAKKYNGEVRKDK
VLVLLVEYDDFKHNNIEQEPGYMYSDDFNQEHYEKMLFGDEPFTLHDGSKIETFKQYYEEQSGGSYTVDGTVSKWLTVPG
KAADYGADAGEGHDNKGPLGPRDLIKDALKAAVESGIDLSEFDQFDQYDIDGDGNKNEPDGLVDHLMVIHAGVGQEAGGG
KLGDDAIWSHRWTIGQKPFPIDGTTAKVPYWDGKMAAFDYTIEPEDGAVGVFAHEYGHDLGLPDEYDTKYSGGGEPVQSW
SIMSGGSWAGKIAGTTPTSFSPQNKEFFQKTMGGNWANIVEIDYEKLNRGIGYATYLDQSVTKSNRPGLIRVNLPDKDVK
GIEPAFGQKYYYSTKGDDLHTTLETPLFDLTSATNATFDFKSLYEIETGYDFLEVHAVTEDGTKTLIDTIGNKDVKDGAD
TTLGEWVDKSYDLSQFKGKKVKLVFEYVTDGGLALNGFTLDNASLTVDGNVVFSDDAEGETQFKLNGFVVSNGIEKKSHN
YYVEWRNYAGADEALKYARGPVYNTGMVVWYADASYTDNWVGVHPGHGFLGVVDSHPEAIAGTLNGKPTFKDSTRYQIAD
AAFSFDQTPAWKVVSPTRGTFEYNGLPGVAKFDDSKVYINNQIPDAGRILPKLGLKFEVVGQADDKSAGAVRLYR

Specific function: Neutral metalloprotease that is secreted to degrade antibacterial proteins produced by the insect host for its defense (attacins and cecropins). Probably degrades some unknown crucial protein(s) too, since it is toxic when injected to insect larvae [H]

COG id: COG4412

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M6 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012300
- InterPro:   IPR008757 [H]

Pfam domain/function: PF05547 Peptidase_M6 [H]

EC number: NA

Molecular weight: Translated: 86942; Mature: 86942

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKPFKVLSALAVAAVLGGAFSFGSPAVQAETSAKATATSPIDDHLIPEERLANALKKR
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
GVINEKASDEETKKAVEKYVEKKKGDKPGKDEMVGDQVTKEASEFLKKVKDAKTDTKEKG
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHC
KEPASGQTEGTVPAKSALNGKVPTTPAKAKKYNGEVRKDKVLVLLVEYDDFKHNNIEQEP
CCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCC
GYMYSDDFNQEHYEKMLFGDEPFTLHDGSKIETFKQYYEEQSGGSYTVDGTVSKWLTVPG
CEEECCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCEEECCCCEEEEECCC
KAADYGADAGEGHDNKGPLGPRDLIKDALKAAVESGIDLSEFDQFDQYDIDGDGNKNEPD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCH
GLVDHLMVIHAGVGQEAGGGKLGDDAIWSHRWTIGQKPFPIDGTTAKVPYWDGKMAAFDY
HHHHHHHHHHCCCCCCCCCCCCCCCCHHCCEEECCCCCCCCCCCEEECCCCCCCEEEEEE
TIEPEDGAVGVFAHEYGHDLGLPDEYDTKYSGGGEPVQSWSIMSGGSWAGKIAGTTPTSF
EECCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEECCCCCCCC
SPQNKEFFQKTMGGNWANIVEIDYEKLNRGIGYATYLDQSVTKSNRPGLIRVNLPDKDVK
CCCCHHHHHHHHCCCEEEEEEEEHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCC
GIEPAFGQKYYYSTKGDDLHTTLETPLFDLTSATNATFDFKSLYEIETGYDFLEVHAVTE
CCCCCCCCEEEEECCCCCEEEECCCCCHHHHCCCCCCCCHHHHEECCCCCCEEEEEEECC
DGTKTLIDTIGNKDVKDGADTTLGEWVDKSYDLSQFKGKKVKLVFEYVTDGGLALNGFTL
CCHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHCCCEEEEEEEEECCCCEEEEEEEE
DNASLTVDGNVVFSDDAEGETQFKLNGFVVSNGIEKKSHNYYVEWRNYAGADEALKYARG
CCCEEEECCCEEECCCCCCCEEEEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHCC
PVYNTGMVVWYADASYTDNWVGVHPGHGFLGVVDSHPEAIAGTLNGKPTFKDSTRYQIAD
CCCCCCEEEEEECCCCCCCEEEECCCCCEEEEECCCCCCEEECCCCCCCCCCCCCEEEEH
AAFSFDQTPAWKVVSPTRGTFEYNGLPGVAKFDDSKVYINNQIPDAGRILPKLGLKFEVV
HHHCCCCCCCEEEECCCCCCEEECCCCCCEEECCCEEEECCCCCCHHHHHHHCCCEEEEE
GQADDKSAGAVRLYR
ECCCCCCCCEEEECC
>Mature Secondary Structure
MKKKPFKVLSALAVAAVLGGAFSFGSPAVQAETSAKATATSPIDDHLIPEERLANALKKR
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
GVINEKASDEETKKAVEKYVEKKKGDKPGKDEMVGDQVTKEASEFLKKVKDAKTDTKEKG
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHC
KEPASGQTEGTVPAKSALNGKVPTTPAKAKKYNGEVRKDKVLVLLVEYDDFKHNNIEQEP
CCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCC
GYMYSDDFNQEHYEKMLFGDEPFTLHDGSKIETFKQYYEEQSGGSYTVDGTVSKWLTVPG
CEEECCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCEEECCCCEEEEECCC
KAADYGADAGEGHDNKGPLGPRDLIKDALKAAVESGIDLSEFDQFDQYDIDGDGNKNEPD
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCH
GLVDHLMVIHAGVGQEAGGGKLGDDAIWSHRWTIGQKPFPIDGTTAKVPYWDGKMAAFDY
HHHHHHHHHHCCCCCCCCCCCCCCCCHHCCEEECCCCCCCCCCCEEECCCCCCCEEEEEE
TIEPEDGAVGVFAHEYGHDLGLPDEYDTKYSGGGEPVQSWSIMSGGSWAGKIAGTTPTSF
EECCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEECCCCCCCC
SPQNKEFFQKTMGGNWANIVEIDYEKLNRGIGYATYLDQSVTKSNRPGLIRVNLPDKDVK
CCCCHHHHHHHHCCCEEEEEEEEHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCCCC
GIEPAFGQKYYYSTKGDDLHTTLETPLFDLTSATNATFDFKSLYEIETGYDFLEVHAVTE
CCCCCCCCEEEEECCCCCEEEECCCCCHHHHCCCCCCCCHHHHEECCCCCCEEEEEEECC
DGTKTLIDTIGNKDVKDGADTTLGEWVDKSYDLSQFKGKKVKLVFEYVTDGGLALNGFTL
CCHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHCCCEEEEEEEEECCCCEEEEEEEE
DNASLTVDGNVVFSDDAEGETQFKLNGFVVSNGIEKKSHNYYVEWRNYAGADEALKYARG
CCCEEEECCCEEECCCCCCCEEEEEEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHCC
PVYNTGMVVWYADASYTDNWVGVHPGHGFLGVVDSHPEAIAGTLNGKPTFKDSTRYQIAD
CCCCCCEEEEEECCCCCCCEEEECCCCCEEEEECCCCCCEEECCCCCCCCCCCCCEEEEH
AAFSFDQTPAWKVVSPTRGTFEYNGLPGVAKFDDSKVYINNQIPDAGRILPKLGLKFEVV
HHHCCCCCCCEEEECCCCCCEEECCCCCCEEECCCEEEECCCCCCHHHHHHHCCCEEEEE
GQADDKSAGAVRLYR
ECCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2089225; 6421577 [H]