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The map label for this gene is ywcA [H]

Identifier: 152974779

GI number: 152974779

Start: 1091384

End: 1092934

Strand: Direct

Name: ywcA [H]

Synonym: Bcer98_0970

Alternate gene names: 152974779

Gene position: 1091384-1092934 (Clockwise)

Preceding gene: 152974778

Following gene: 152974780

Centisome position: 26.7

GC content: 38.62

Gene sequence:

>1551_bases
ATGGACTATAAAGTGGTAGTAATGTTTGGATTCATTGTGATTATGACGCTTGTTATTACCTATTATGCCTCGAAAAAAAC
AAGTAATGCGCGTTCTTTTTATACAGCTGGAGGGGGACTAAAGGGATGGCAAAATGGTTTTGCAATTGCCGGTGATTTTA
TGTCAGCCTCTTCTTTTTTAGGTCTTATTGGTGCGATTTCCCTTCTAGGATATGACGGATATTTTTTAATGTATGGTGCG
CTTGTATCGTATTTAGTCGTTTTGCTCCTAGTGGCCGAACCGCTTCGCAATCTAGGGAAATATACATTGGCAGATATGAT
TACAGAGCGTTTTCAAAATAAAAAAGTGCGAGGTATTACGGCATTTAATGCCCTTACGATTTCTGTTTTTTACATGCTTG
CACAGCTTGTCGCAGCGGGAGCGCTCTTTAAATTACTATTAAATATTCAATATGAAATATCTGTCGTTATTGTAGGGCTT
GTTATGCTTGTATTTGTTATTTTTGGCGGTATGACAGCGACGAGCTGGGTACAAATTACGAAAGCATTTTTATTATTAGG
CGGGACATTTCTCATTTTCATCATGGTAATGAGCAAATTCGATTTTAATGTTTTTCGGATTTTTGAAGAAATGAAAACAG
CAACGCCCCTTCAAGAGGCTTACCTACATCCAGGTGCAAAATATACAAATGGATTAGATGCCTTTTCTTTAACGCTTGGC
TTAATTCTTGGTACAGCTGGCCTTCCTCATGTTTTAAGCCGCTTTTTAACCGTTCCAAATGCAAAAGTAGCGAGAAAATC
TGTTGCTTATTCCATTTGGATCATTGGCTTATTTTATATTATGGTCATCTTTTTAGGATTTGCTGCTGCAAAATTCGTTG
GAGCTACAGAGATTATGAAAGCGAATCCAGCGGGAAACATGGCGGCACCATTGCTAGCCAAAATATTAGGCGGTGACATG
TTATTTGCTGTTATATCAGCTGTCTCCTTTGCTACTATTCTTGCTGTCGTAGCGGGAATTGTTGTCACAGGGGCAACCGC
ATTCTCTCATGATTTTTATAATGAAATTATTCGAGAAGGAAAAGCGACTGAAAAGGAACAGCTTCGCATGGCGCGATTTG
CTTCGATTGGCATTACAGTTTTCTCTATTATATTGGCATTGTTTGTTCAAAAAATGAATGTCGCCTTTCTTTCATCATTA
GCATTAACAGTTGCAGCAAGCTCTAATTTGCCTGTCATTTTATTTACTGTATATTGGAAGCGTTTTAATATAGCAGGAGC
CATTACAGGCATGCTCGTAGGTTTACTTGGCAGTATGATTCTCGTTGCGCTTAGTCCGAGTGTATGGAGTCCGAAAGTAG
GAGAAGCGCTTTTTGTAGGAGAACCGTTATTTCCATTGTCTTCCCCAGGCATTGTCTCCATTCCGTTAGGATTTCTTGGA
GCTTATATAGGTACAATTTTATTTGCGAAAAGAAGTAAGACGGGTAATTTTGAAGAAATATTGGTGAAGTCGAATACAGG
AAGCAATGTGAAAGGTATTAGTCATCATTAA

Upstream 100 bases:

>100_bases
ATGACTATTGTCATTTGTCATCTATATGTAAAAAAAGCAGCTTACTTTGATGCATTAGCTGAGCAAGTGTTAAGGGAAGA
GGCAGAGGGGAGAAAAGTAG

Downstream 100 bases:

>100_bases
GTGAAATGAGGGAGGAAAATATGAGGAAAATACAGTTTAAATGTTATGGCCGATCCCAAATAGAAGAAGCGGAGCTACAT
ATAACAGAAGATATGGTCAT

Product: SSS family solute/sodium (Na+) symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MDYKVVVMFGFIVIMTLVITYYASKKTSNARSFYTAGGGLKGWQNGFAIAGDFMSASSFLGLIGAISLLGYDGYFLMYGA
LVSYLVVLLLVAEPLRNLGKYTLADMITERFQNKKVRGITAFNALTISVFYMLAQLVAAGALFKLLLNIQYEISVVIVGL
VMLVFVIFGGMTATSWVQITKAFLLLGGTFLIFIMVMSKFDFNVFRIFEEMKTATPLQEAYLHPGAKYTNGLDAFSLTLG
LILGTAGLPHVLSRFLTVPNAKVARKSVAYSIWIIGLFYIMVIFLGFAAAKFVGATEIMKANPAGNMAAPLLAKILGGDM
LFAVISAVSFATILAVVAGIVVTGATAFSHDFYNEIIREGKATEKEQLRMARFASIGITVFSIILALFVQKMNVAFLSSL
ALTVAASSNLPVILFTVYWKRFNIAGAITGMLVGLLGSMILVALSPSVWSPKVGEALFVGEPLFPLSSPGIVSIPLGFLG
AYIGTILFAKRSKTGNFEEILVKSNTGSNVKGISHH

Sequences:

>Translated_516_residues
MDYKVVVMFGFIVIMTLVITYYASKKTSNARSFYTAGGGLKGWQNGFAIAGDFMSASSFLGLIGAISLLGYDGYFLMYGA
LVSYLVVLLLVAEPLRNLGKYTLADMITERFQNKKVRGITAFNALTISVFYMLAQLVAAGALFKLLLNIQYEISVVIVGL
VMLVFVIFGGMTATSWVQITKAFLLLGGTFLIFIMVMSKFDFNVFRIFEEMKTATPLQEAYLHPGAKYTNGLDAFSLTLG
LILGTAGLPHVLSRFLTVPNAKVARKSVAYSIWIIGLFYIMVIFLGFAAAKFVGATEIMKANPAGNMAAPLLAKILGGDM
LFAVISAVSFATILAVVAGIVVTGATAFSHDFYNEIIREGKATEKEQLRMARFASIGITVFSIILALFVQKMNVAFLSSL
ALTVAASSNLPVILFTVYWKRFNIAGAITGMLVGLLGSMILVALSPSVWSPKVGEALFVGEPLFPLSSPGIVSIPLGFLG
AYIGTILFAKRSKTGNFEEILVKSNTGSNVKGISHH
>Mature_516_residues
MDYKVVVMFGFIVIMTLVITYYASKKTSNARSFYTAGGGLKGWQNGFAIAGDFMSASSFLGLIGAISLLGYDGYFLMYGA
LVSYLVVLLLVAEPLRNLGKYTLADMITERFQNKKVRGITAFNALTISVFYMLAQLVAAGALFKLLLNIQYEISVVIVGL
VMLVFVIFGGMTATSWVQITKAFLLLGGTFLIFIMVMSKFDFNVFRIFEEMKTATPLQEAYLHPGAKYTNGLDAFSLTLG
LILGTAGLPHVLSRFLTVPNAKVARKSVAYSIWIIGLFYIMVIFLGFAAAKFVGATEIMKANPAGNMAAPLLAKILGGDM
LFAVISAVSFATILAVVAGIVVTGATAFSHDFYNEIIREGKATEKEQLRMARFASIGITVFSIILALFVQKMNVAFLSSL
ALTVAASSNLPVILFTVYWKRFNIAGAITGMLVGLLGSMILVALSPSVWSPKVGEALFVGEPLFPLSSPGIVSIPLGFLG
AYIGTILFAKRSKTGNFEEILVKSNTGSNVKGISHH

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=455, Percent_Identity=23.2967032967033, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1790503, Length=526, Percent_Identity=41.4448669201521, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1787251, Length=447, Percent_Identity=23.9373601789709, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 55614; Mature: 55614

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCCCCHHHEEEECCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHCCCCCCHHHEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]