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The map label for this gene is mecA1 [H]

Identifier: 152974718

GI number: 152974718

Start: 1024382

End: 1025056

Strand: Direct

Name: mecA1 [H]

Synonym: Bcer98_0906

Alternate gene names: 152974718

Gene position: 1024382-1025056 (Clockwise)

Preceding gene: 152974716

Following gene: 152974719

Centisome position: 25.06

GC content: 32.89

Gene sequence:

>675_bases
TTGGATATTGAAAGAATTAATGATCATACGATGAAATTTTTCATTACGTACGTTGATATAGAGGATAGAGGATTTAATCG
CGAAGAAATTTGGTATAATCGCGAGCGAAGTGAACAATTATTTTGGGAAATGATGGATGAAGCACGTGATTACGATGACT
TCTTTATTGATGGACCATTGTGGATTCAAGTACAAGCGTTAGACAAAGGGATTGAAGTGCTTGTAACGAAAGCACAGCTT
TCAAAAGATGGACAAAAATTAGAATTACCGATAGGTCTCGATAAAATTATTGATATTCCTCTAGATGAAAGCATTGAATC
GTTATTTCAACAAGAATTAGAGGAAGAAGGAACGGTTACGAATTTTAATGAAGATGGAACACTTGGATTTTTAATTAAGT
TTGAAGATTTTGAAGATGTTATTTCATTAAGTCATCGCCTAATTTTTGAAGATATAAAAGACCAACTATATTCATTTGAA
AATCGTTATTATGTATATGTTGAATTCGATGAAGTGCTACACGATGAGGAAGAAATTGACCGTATTTTAAGTATTATTTT
AGAATATGGAGAGGAATCTACTTTAACGATTCACCGTGTGAGTGAGTATGGGAAAGAGATTATGAGCGAACATGCACTTG
AGACAATTCGTAAGCATTTTCCTTCTAAAACGTAG

Upstream 100 bases:

>100_bases
AGAATCTTATCATAAAATGAAAGTACAAGAATCTATTGATTTGTCATATGAGTGGGGAATCCCTTCATAACAATTCCAAA
TAGGAAGGGAGAGTTGGATT

Downstream 100 bases:

>100_bases
GCCGATTTCAATTATATGAAATCGGCTTTTTATATGATGGGTATAATAGGGAAAGTATACTTTCGCTAGTAGAAAGCTTT
TTTAGTAAGGGGGGTAGAAA

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MDIERINDHTMKFFITYVDIEDRGFNREEIWYNRERSEQLFWEMMDEARDYDDFFIDGPLWIQVQALDKGIEVLVTKAQL
SKDGQKLELPIGLDKIIDIPLDESIESLFQQELEEEGTVTNFNEDGTLGFLIKFEDFEDVISLSHRLIFEDIKDQLYSFE
NRYYVYVEFDEVLHDEEEIDRILSIILEYGEESTLTIHRVSEYGKEIMSEHALETIRKHFPSKT

Sequences:

>Translated_224_residues
MDIERINDHTMKFFITYVDIEDRGFNREEIWYNRERSEQLFWEMMDEARDYDDFFIDGPLWIQVQALDKGIEVLVTKAQL
SKDGQKLELPIGLDKIIDIPLDESIESLFQQELEEEGTVTNFNEDGTLGFLIKFEDFEDVISLSHRLIFEDIKDQLYSFE
NRYYVYVEFDEVLHDEEEIDRILSIILEYGEESTLTIHRVSEYGKEIMSEHALETIRKHFPSKT
>Mature_224_residues
MDIERINDHTMKFFITYVDIEDRGFNREEIWYNRERSEQLFWEMMDEARDYDDFFIDGPLWIQVQALDKGIEVLVTKAQL
SKDGQKLELPIGLDKIIDIPLDESIESLFQQELEEEGTVTNFNEDGTLGFLIKFEDFEDVISLSHRLIFEDIKDQLYSFE
NRYYVYVEFDEVLHDEEEIDRILSIILEYGEESTLTIHRVSEYGKEIMSEHALETIRKHFPSKT

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008681 [H]

Pfam domain/function: PF05389 MecA [H]

EC number: NA

Molecular weight: Translated: 26745; Mature: 26745

Theoretical pI: Translated: 4.04; Mature: 4.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIERINDHTMKFFITYVDIEDRGFNREEIWYNRERSEQLFWEMMDEARDYDDFFIDGPL
CCCCCCCCCEEEEEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCEEECCCE
WIQVQALDKGIEVLVTKAQLSKDGQKLELPIGLDKIIDIPLDESIESLFQQELEEEGTVT
EEEEEECCCCHHHEEEHHHHCCCCCEEEECCCHHHHCCCCCCHHHHHHHHHHHHHCCCEE
NFNEDGTLGFLIKFEDFEDVISLSHRLIFEDIKDQLYSFENRYYVYVEFDEVLHDEEEID
CCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCHHHHH
RILSIILEYGEESTLTIHRVSEYGKEIMSEHALETIRKHFPSKT
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDIERINDHTMKFFITYVDIEDRGFNREEIWYNRERSEQLFWEMMDEARDYDDFFIDGPL
CCCCCCCCCEEEEEEEEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCCEEECCCE
WIQVQALDKGIEVLVTKAQLSKDGQKLELPIGLDKIIDIPLDESIESLFQQELEEEGTVT
EEEEEECCCCHHHEEEHHHHCCCCCEEEECCCHHHHCCCCCCHHHHHHHHHHHHHCCCEE
NFNEDGTLGFLIKFEDFEDVISLSHRLIFEDIKDQLYSFENRYYVYVEFDEVLHDEEEID
CCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCHHHHH
RILSIILEYGEESTLTIHRVSEYGKEIMSEHALETIRKHFPSKT
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]