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The map label for this gene is clpB [H]

Identifier: 152974698

GI number: 152974698

Start: 1001055

End: 1003655

Strand: Direct

Name: clpB [H]

Synonym: Bcer98_0885

Alternate gene names: 152974698

Gene position: 1001055-1003655 (Clockwise)

Preceding gene: 152974697

Following gene: 152974700

Centisome position: 24.49

GC content: 39.22

Gene sequence:

>2601_bases
ATGGACTTAAATCAAATGACGACAAAAACACAAGAAGCGATTATGAGTGCCCAATCTTTAGCGGTATCTCATCATCACCA
AGAAGTAGATACTGTTCATCTATTGCTTGCGTTGCTAAAGCAGCAGGATGGATTAGCGGTACGTATTTTTCAAAAAATGA
ATGTGAATATAGAACAATTAACGAAAGAAGTGGAAACGCTTATTCAGAAAAAGCCATCTGTAACAGGAAGTGGGATAGAA
GCTGGGAAACTGTATATTACAGGCGCTTTGCAACAATTGCTCGTTAAGGCAGAAGCGGAAGCGAAAAAACTGCAAGATGA
ATACATTTCAGTAGAACATGTATTATTAGCTTTTTGTGAAGAAACAGGGGATGTAAATCGTCTATTTTCTAATTTCCGTA
TTACAAAGGATACATTACTACAGTCTTTAATGGCAGTTCGGGGGAATCAAAGAGTGACAAGTCAAAATCCAGAAGTAACA
TATGAAGCGTTAGAGAAATATGGCCGTGATTTGGTCGCAGAAGTGAAACAAGGAAAAATTGACCCTGTAATTGGACGCGA
TAGTGAGATTCGCCGCGTCATTCGCATTCTTTCGCGTAAAACAAAAAATAACCCTGTGTTAATTGGTGAACCTGGTGTGG
GGAAAACAGCCATTGTGGAAGGATTAGCGCAGCGAATTGTAAAAAAAGATGTACCGGAAGGATTAAAAGATCGCACCATC
TTTGCGTTAGATATGAGCGCCCTTGTAGCTGGAGCAAAATTCCGCGGGGAGTTTGAAGAACGTTTACAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGACGTATTCTGTTATTCATTGATGAACTGCATACAATTGTAGGAGCTGGGAAAACAGAAG
GAGCAATGGATGCTGGGAATATGTTGAAACCGATGCTTGCGCGCGGCGAGCTTCATTGTATCGGTGCGACAACTTTAGAT
GAGTACCGAAAATATATTGAAAAAGATCCGGCGTTAGAACGTCGTTTTCAACAAGTATTAGCGGAAGAGCCAACGGTGGA
AGATACGATTTCTATTTTACGTGGTCTCAAAGAGCGTTTTGAAATTTATCATGGTGTAAATATCCATGACCGTGCGCTTG
TAGCAGCTTCTGTATTATCTGATCGCTATATCTCTGATCGTTTTTTACCGGATAAAGCAATTGATCTTGTTGATGAGGCA
TGCGCTACCATTCGGACAGAAATTGATTCTATGCCAACAGAATTAGATGAAGTAACGCGCCGCATTATGCAGTTAGAAAT
TGAAGAAGCGGCGCTTGGAAAAGAAACGGATCGCGGTAGTCAAGAAAGGTTGAAAACATTACAGCACGAGTTATCTGATT
TAAAAGAAGTGGCAAGTGGCATGCGTGCGCAGTGGGAAAAAGAAAAAGAAGAAATTCATAAAGTACGCAACTTGCGCGAG
AAATTAGAGCGTTTGCGCCGTGAACTGGAAGAAGCAGAAGGAAACTATGATTTAAATAAAGCGGCTGAACTTCGTCACGG
TAAAATTCCAGAGGTAGAAAAAGAATTAAAAGTAGCAGAAGAAGCCGGAACACATCATGAAAACGAGAACCGTTTGCTTC
GTGAAGAAGTAAGTGAAGAAGAAATCGCAAATATTGTTTCGCGCTGGACAGGAATTCCAGTAGCGAAATTAGTAGAAGGA
GAACGTGAAAAGTTACTGCGATTAGAGCAAATTTTATCAGAGCGTGTAATTGGTCAAGAAGAAGCAGTAAGTCTTGTAGC
AGATGCAGTTCTTCGTGCGAGAGCAGGAATTAAAGACCCGAATCGCCCGATTGGTTCTTTCATTTTCTTAGGACCGACAG
GGGTTGGGAAAACTGAACTTGCGAAAACATTAGCACAGTCGTTATTTGATAGCGAAGAACAAATGATCCGGATAGATATG
TCTGAGTATATGGAAAAACATGCGGTATCCCGTTTAATTGGAGCGCCTCCAGGATATGTAGGATATGAGGAAGGCGGACA
ATTAACAGAAGCGGTTCGTCGCAAACCATATTCCGTTATTTTATTGGATGAAATTGAAAAAGCACATCCGGAAGTGTTTA
ATATTTTATTACAAATGTTAGATGATGGTCGCATTACCGATTCACAAGGACGAACAGTCGACTTTAAAAATACAGTAATT
ATTATGACATCAAATATTGGATCCGCATATTTATTAGAAGGATTACAAGAGAATGGCGCTATAAAAGAGGAAGCAAGAGA
CCTTGTTATGGGGGAACTTAGAGGACATTTTCGTCCTGAGTTTTTAAACCGTGTAGATGAAATTATTTTATTTAAACCAC
TTACAACTCATGAAATAAAAGGAATTGTTGATAAGATTGTAAAAGAATTACAAGGACGTTTAGTGGAGCGTCATATTACA
GTTGCATTAACAGAATCCGCAAAAGAATTTATTGTAGAATCTGGGTTTGACCCTATGTATGGTGCACGTCCGTTAAAAAG
ATATGTGCAGCGCCAAATTGAAACGAAACTTGCAAGAGAATTAATTGCAGGAACAATAATAGATAATAGCCATGTAGTAG
TAGATGTAGAAAATAATGAATTCGTTGTGCATGTGAAATAA

Upstream 100 bases:

>100_bases
TTGATTGTATAAAAAAGGAGATAAGAGTATAATAAATTACAAAAGGTCAAAGAAAGTCAAATAGTCAACAAAGGTCAAAA
AATGTGGAGGAACTGTAAAG

Downstream 100 bases:

>100_bases
AAAATGTCCGGACATTGATCCGGACATTTTTTAATGTTGCTCTGCTGGTTCGTTTGGAATTGCAGCTGCAATTGCCATTA
CAAGAATTGCAAGAACAACT

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 866; Mature: 866

Protein sequence:

>866_residues
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLLALLKQQDGLAVRIFQKMNVNIEQLTKEVETLIQKKPSVTGSGIE
AGKLYITGALQQLLVKAEAEAKKLQDEYISVEHVLLAFCEETGDVNRLFSNFRITKDTLLQSLMAVRGNQRVTSQNPEVT
YEALEKYGRDLVAEVKQGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRALVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKETDRGSQERLKTLQHELSDLKEVASGMRAQWEKEKEEIHKVRNLRE
KLERLRRELEEAEGNYDLNKAAELRHGKIPEVEKELKVAEEAGTHHENENRLLREEVSEEEIANIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVADAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAYLLEGLQENGAIKEEARDLVMGELRGHFRPEFLNRVDEIILFKPLTTHEIKGIVDKIVKELQGRLVERHIT
VALTESAKEFIVESGFDPMYGARPLKRYVQRQIETKLARELIAGTIIDNSHVVVDVENNEFVVHVK

Sequences:

>Translated_866_residues
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLLALLKQQDGLAVRIFQKMNVNIEQLTKEVETLIQKKPSVTGSGIE
AGKLYITGALQQLLVKAEAEAKKLQDEYISVEHVLLAFCEETGDVNRLFSNFRITKDTLLQSLMAVRGNQRVTSQNPEVT
YEALEKYGRDLVAEVKQGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRALVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKETDRGSQERLKTLQHELSDLKEVASGMRAQWEKEKEEIHKVRNLRE
KLERLRRELEEAEGNYDLNKAAELRHGKIPEVEKELKVAEEAGTHHENENRLLREEVSEEEIANIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVADAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAYLLEGLQENGAIKEEARDLVMGELRGHFRPEFLNRVDEIILFKPLTTHEIKGIVDKIVKELQGRLVERHIT
VALTESAKEFIVESGFDPMYGARPLKRYVQRQIETKLARELIAGTIIDNSHVVVDVENNEFVVHVK
>Mature_866_residues
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLLALLKQQDGLAVRIFQKMNVNIEQLTKEVETLIQKKPSVTGSGIE
AGKLYITGALQQLLVKAEAEAKKLQDEYISVEHVLLAFCEETGDVNRLFSNFRITKDTLLQSLMAVRGNQRVTSQNPEVT
YEALEKYGRDLVAEVKQGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRALVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKETDRGSQERLKTLQHELSDLKEVASGMRAQWEKEKEEIHKVRNLRE
KLERLRRELEEAEGNYDLNKAAELRHGKIPEVEKELKVAEEAGTHHENENRLLREEVSEEEIANIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVADAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAYLLEGLQENGAIKEEARDLVMGELRGHFRPEFLNRVDEIILFKPLTTHEIKGIVDKIVKELQGRLVERHIT
VALTESAKEFIVESGFDPMYGARPLKRYVQRQIETKLARELIAGTIIDNSHVVVDVENNEFVVHVK

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=298, Percent_Identity=39.261744966443, Blast_Score=213, Evalue=8e-55,
Organism=Escherichia coli, GI1788943, Length=864, Percent_Identity=54.5138888888889, Blast_Score=936, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=358, Percent_Identity=41.8994413407821, Blast_Score=281, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6320464, Length=712, Percent_Identity=51.9662921348315, Blast_Score=746, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=866, Percent_Identity=41.6859122401848, Blast_Score=672, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 97647; Mature: 97647

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLLALLKQQDGLAVRIFQKMNVNIEQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCHHHH
TKEVETLIQKKPSVTGSGIEAGKLYITGALQQLLVKAEAEAKKLQDEYISVEHVLLAFCE
HHHHHHHHHCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETGDVNRLFSNFRITKDTLLQSLMAVRGNQRVTSQNPEVTYEALEKYGRDLVAEVKQGKI
HCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
DPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
CCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEE
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGN
EEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCHH
MLKPMLARGELHCIGATTLDEYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERF
HHHHHHHCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EIYHGVNIHDRALVAASVLSDRYISDRFLPDKAIDLVDEACATIRTEIDSMPTELDEVTR
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RIMQLEIEEAALGKETDRGSQERLKTLQHELSDLKEVASGMRAQWEKEKEEIHKVRNLRE
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLERLRRELEEAEGNYDLNKAAELRHGKIPEVEKELKVAEEAGTHHENENRLLREEVSEE
HHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCHH
EIANIVSRWTGIPVAKLVEGEREKLLRLEQILSERVIGQEEAVSLVADAVLRARAGIKDP
HHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
NRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDMSEYMEKHAVSRLIGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
CCCCCCHHHHHHHCCCCEEEEHHHHHHHCHHHHHHHHHHHCCCCEECCCCCEEEECCEEE
IMTSNIGSAYLLEGLQENGAIKEEARDLVMGELRGHFRPEFLNRVDEIILFKPLTTHEIK
EEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCHHHHH
GIVDKIVKELQGRLVERHITVALTESAKEFIVESGFDPMYGARPLKRYVQRQIETKLARE
HHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LIAGTIIDNSHVVVDVENNEFVVHVK
HHHHHEECCCEEEEEECCCEEEEEEC
>Mature Secondary Structure
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLLALLKQQDGLAVRIFQKMNVNIEQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCHHHH
TKEVETLIQKKPSVTGSGIEAGKLYITGALQQLLVKAEAEAKKLQDEYISVEHVLLAFCE
HHHHHHHHHCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETGDVNRLFSNFRITKDTLLQSLMAVRGNQRVTSQNPEVTYEALEKYGRDLVAEVKQGKI
HCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
DPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
CCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEE
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGN
EEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCHH
MLKPMLARGELHCIGATTLDEYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERF
HHHHHHHCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EIYHGVNIHDRALVAASVLSDRYISDRFLPDKAIDLVDEACATIRTEIDSMPTELDEVTR
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RIMQLEIEEAALGKETDRGSQERLKTLQHELSDLKEVASGMRAQWEKEKEEIHKVRNLRE
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLERLRRELEEAEGNYDLNKAAELRHGKIPEVEKELKVAEEAGTHHENENRLLREEVSEE
HHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCHH
EIANIVSRWTGIPVAKLVEGEREKLLRLEQILSERVIGQEEAVSLVADAVLRARAGIKDP
HHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
NRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDMSEYMEKHAVSRLIGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
CCCCCCHHHHHHHCCCCEEEEHHHHHHHCHHHHHHHHHHHCCCCEECCCCCEEEECCEEE
IMTSNIGSAYLLEGLQENGAIKEEARDLVMGELRGHFRPEFLNRVDEIILFKPLTTHEIK
EEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCHHHHH
GIVDKIVKELQGRLVERHITVALTESAKEFIVESGFDPMYGARPLKRYVQRQIETKLARE
HHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LIAGTIIDNSHVVVDVENNEFVVHVK
HHHHHEECCCEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]