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The map label for this gene is lepB [H]

Identifier: 152974671

GI number: 152974671

Start: 974616

End: 975182

Strand: Direct

Name: lepB [H]

Synonym: Bcer98_0858

Alternate gene names: 152974671

Gene position: 974616-975182 (Clockwise)

Preceding gene: 152974670

Following gene: 152974672

Centisome position: 23.85

GC content: 35.8

Gene sequence:

>567_bases
ATGAAGCAAACTTTGAAAAAAGAAAGCGTAGAGTGGATGAGAACGATCCTTATCGGGATACTACTAGCTCTTTTTTTTCG
AACGTTTTTCTTCTCGACTTATGTTGTAGAGGGAAAGTCGATGATGCCAACACTTCAAGATGGTAATATGCTTGTTGTGA
ACAAAGTGAGCTATCAAGTTGGAGAGTTACATCGATTTGATGTTGTTGTATTCCATGCGAATAAAAAAGAGGACTATGTA
AAACGAATCATTGGTTTACCTGGAGATTATATTGAATATAAGCAGGATAAATTATATATTAATGGTCAATTTGTTGATGA
ACCGTATTTAGAAACATATAAGGAACAAGTGAAAGGACGCCAGTTGACAGGAGATTTTAAGTTGGAAGAGTTAACGAAAA
AAAAGGTTGTGCCAAAAGGATATATTTTTGTACTTGGCGATAACCGTCTTGGTAGCTGGGACAGCAGACATTTTGGTTTT
ATAAAAGCAGATGCGGTTGTTGGAAAAGTCGATTTACGTTATTGGCCGATTAACGAAATGCAAATGAACTTTTCAAAAGG
TGAGTAG

Upstream 100 bases:

>100_bases
TGTTGGTAAGAAAATTGAAGTGAAATTAGAACTGCATTGAGGAGAGAAGTCCGCGCTGTACATACAGCTTCATTGTAGAA
AAGGGTGAGGGGAGAGGCTG

Downstream 100 bases:

>100_bases
AATGATTTATAATATAGAAAAGAGGAAAAAAGGCAAGCAGTCTCTGTTTGTCTTTTTTCGTGTCCTATAATACAATGATG
ACAGCAAACTAACGTTCGTT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MKQTLKKESVEWMRTILIGILLALFFRTFFFSTYVVEGKSMMPTLQDGNMLVVNKVSYQVGELHRFDVVVFHANKKEDYV
KRIIGLPGDYIEYKQDKLYINGQFVDEPYLETYKEQVKGRQLTGDFKLEELTKKKVVPKGYIFVLGDNRLGSWDSRHFGF
IKADAVVGKVDLRYWPINEMQMNFSKGE

Sequences:

>Translated_188_residues
MKQTLKKESVEWMRTILIGILLALFFRTFFFSTYVVEGKSMMPTLQDGNMLVVNKVSYQVGELHRFDVVVFHANKKEDYV
KRIIGLPGDYIEYKQDKLYINGQFVDEPYLETYKEQVKGRQLTGDFKLEELTKKKVVPKGYIFVLGDNRLGSWDSRHFGF
IKADAVVGKVDLRYWPINEMQMNFSKGE
>Mature_188_residues
MKQTLKKESVEWMRTILIGILLALFFRTFFFSTYVVEGKSMMPTLQDGNMLVVNKVSYQVGELHRFDVVVFHANKKEDYV
KRIIGLPGDYIEYKQDKLYINGQFVDEPYLETYKEQVKGRQLTGDFKLEELTKKKVVPKGYIFVLGDNRLGSWDSRHFGF
IKADAVVGKVDLRYWPINEMQMNFSKGE

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 22016; Mature: 22016

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTLKKESVEWMRTILIGILLALFFRTFFFSTYVVEGKSMMPTLQDGNMLVVNKVSYQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCCCEEEEEECCCCC
GELHRFDVVVFHANKKEDYVKRIIGLPGDYIEYKQDKLYINGQFVDEPYLETYKEQVKGR
CCEEEEEEEEEECCCHHHHHHHHHCCCCCHHEECCCEEEECCEECCCHHHHHHHHHHCCC
QLTGDFKLEELTKKKVVPKGYIFVLGDNRLGSWDSRHFGFIKADAVVGKVDLRYWPINEM
CCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEECEEEEEEEEEEECCCHH
QMNFSKGE
EECCCCCC
>Mature Secondary Structure
MKQTLKKESVEWMRTILIGILLALFFRTFFFSTYVVEGKSMMPTLQDGNMLVVNKVSYQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCCCEEEEEECCCCC
GELHRFDVVVFHANKKEDYVKRIIGLPGDYIEYKQDKLYINGQFVDEPYLETYKEQVKGR
CCEEEEEEEEEECCCHHHHHHHHHCCCCCHHEECCCEEEECCEECCCHHHHHHHHHHCCC
QLTGDFKLEELTKKKVVPKGYIFVLGDNRLGSWDSRHFGFIKADAVVGKVDLRYWPINEM
CCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEECEEEEEEEEEEECCCHH
QMNFSKGE
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8801417 [H]