Click here to switch to the map view.

The map label for this gene is ntdR [H]

Identifier: 152974650

GI number: 152974650

Start: 951026

End: 952039

Strand: Direct

Name: ntdR [H]

Synonym: Bcer98_0837

Alternate gene names: 152974650

Gene position: 951026-952039 (Clockwise)

Preceding gene: 152974647

Following gene: 152974651

Centisome position: 23.27

GC content: 36.79

Gene sequence:

>1014_bases
GTGTCAACGATTGAGGACGTGGCGAAATTAGCGGGATTATCAAGAACAACGGTTTCTCGGGTGATTAATAATCATCCGTA
CGTATCAGATGAGAAGAAAAAGAGAGTTCAATTAGCGATGAAGCATTTAGGCTTCGTACCTAATTCGGCAGCAAGAAGAC
TTCGAAAACAAAAAACGGAGACAATTGCAGTTCTCGTTCCAAGAATTACAAATCCTTTTTTCAGTAGATTTATTGAAGCA
ATTGAGATTGCTGCTTCTGAACATAAATATAAACTGATTATTTGTCAAACAAGATACTTACCAGAAAAAGAGATGGAATA
CTTACAACTGTTATCAACAAAACAAGTAGATGGCATTATTCTATGTTCCCTTGAGAACTCATGGGAAGATGTGGAGCCAT
ATTTACAACACGGTCCAATTGTGTTATGTAATGAATATATTGAAGAAGCAAATATTCCAACGGTTAAATTTGATCATGCT
CAAGGAGCATATATTGCGGCAAAACATGTATTAGAGCAAGGGTATCGCAATCTTATTTTCTGCCGTGGCAATGAAACAAA
GGTAATTAGCCAACAACGAAAAATGGGATTTTTGCGTGCAGTTACTGAGCAGGGGAAACATGTAGAAGGAATTGATTTTA
TTGAAAACGTTTTCTCGTGGGGAGATGGGAAAAGACTCTTTCATGATGTATTAAAGGACAAAAAAAATCCTACCGCTATT
TTGGCAGGAGGCGATGAGGTTGCAGCTGGCATTATTTCAGAGGCGAAACGCCATAACTGGAGTATTCCAGATAACCTAGC
TGTAATTGGTTTTGATAATCAAATTTTATCAAAAATTACAGATCCTGGTATTACGACAATGGAACAACCAATCGATGACA
TGGCTCGAAAAGTTATAGATTTAATGATAGATAAAATCCATACAAAAAATTATCGCAAAAAAGAACTATATGAGTTTGAG
CTGGAACTCTTGGTGAAAGGTTCAACGATGAAAGATGCGATGTTACTAGCCTAG

Upstream 100 bases:

>100_bases
TATTAATATAGTAAAATCATAAGAACTCATATTGCAGTTTCCAATAATATACTATATAATTTACTAAAGAAAACGTTTTC
ATACAAAGGGGGAGAATTTC

Downstream 100 bases:

>100_bases
TAGACAATGTCTGCTAGGTTTTTTATGTGTATACACGATTATTCTTCGTGAACACAGTCATCGCATTTATTATGGTATGC
TTCGTGTTGCTCATCAATTT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSTIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTETIAVLVPRITNPFFSRFIEA
IEIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGIILCSLENSWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHA
QGAYIAAKHVLEQGYRNLIFCRGNETKVISQQRKMGFLRAVTEQGKHVEGIDFIENVFSWGDGKRLFHDVLKDKKNPTAI
LAGGDEVAAGIISEAKRHNWSIPDNLAVIGFDNQILSKITDPGITTMEQPIDDMARKVIDLMIDKIHTKNYRKKELYEFE
LELLVKGSTMKDAMLLA

Sequences:

>Translated_337_residues
MSTIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTETIAVLVPRITNPFFSRFIEA
IEIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGIILCSLENSWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHA
QGAYIAAKHVLEQGYRNLIFCRGNETKVISQQRKMGFLRAVTEQGKHVEGIDFIENVFSWGDGKRLFHDVLKDKKNPTAI
LAGGDEVAAGIISEAKRHNWSIPDNLAVIGFDNQILSKITDPGITTMEQPIDDMARKVIDLMIDKIHTKNYRKKELYEFE
LELLVKGSTMKDAMLLA
>Mature_336_residues
STIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTETIAVLVPRITNPFFSRFIEAI
EIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGIILCSLENSWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHAQ
GAYIAAKHVLEQGYRNLIFCRGNETKVISQQRKMGFLRAVTEQGKHVEGIDFIENVFSWGDGKRLFHDVLKDKKNPTAIL
AGGDEVAAGIISEAKRHNWSIPDNLAVIGFDNQILSKITDPGITTMEQPIDDMARKVIDLMIDKIHTKNYRKKELYEFEL
ELLVKGSTMKDAMLLA

Specific function: Positively regulates the ntdABC operon and negatively regulates its own transcription. Binds to NTD to induce ntdABC transcription [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=329, Percent_Identity=30.6990881458967, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1787948, Length=317, Percent_Identity=30.5993690851735, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1790194, Length=318, Percent_Identity=27.3584905660377, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1789202, Length=303, Percent_Identity=28.7128712871287, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1788474, Length=311, Percent_Identity=29.2604501607717, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1789068, Length=325, Percent_Identity=24, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI48994940, Length=329, Percent_Identity=24.3161094224924, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1790715, Length=311, Percent_Identity=24.4372990353698, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1787580, Length=317, Percent_Identity=25.5520504731861, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1786268, Length=333, Percent_Identity=23.7237237237237, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790689, Length=192, Percent_Identity=26.5625, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786540, Length=322, Percent_Identity=22.360248447205, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787906, Length=324, Percent_Identity=20.679012345679, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38341; Mature: 38210

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTE
CCCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TIAVLVPRITNPFFSRFIEAIEIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGII
EEEEEECHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEE
LCSLENSWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHAQGAYIAAKHVLEQGYRNLIF
EEECCCCCHHHHHHHHCCCEEEEHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCEEEE
CRGNETKVISQQRKMGFLRAVTEQGKHVEGIDFIENVFSWGDGKRLFHDVLKDKKNPTAI
ECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEE
LAGGDEVAAGIISEAKRHNWSIPDNLAVIGFDNQILSKITDPGITTMEQPIDDMARKVID
EECCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LMIDKIHTKNYRKKELYEFELELLVKGSTMKDAMLLA
HHHHHHHCCCCHHHHHHHHEEEHEEECCCCCHHHHCC
>Mature Secondary Structure 
STIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTE
CCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TIAVLVPRITNPFFSRFIEAIEIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGII
EEEEEECHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEE
LCSLENSWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHAQGAYIAAKHVLEQGYRNLIF
EEECCCCCHHHHHHHHCCCEEEEHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCEEEE
CRGNETKVISQQRKMGFLRAVTEQGKHVEGIDFIENVFSWGDGKRLFHDVLKDKKNPTAI
ECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEE
LAGGDEVAAGIISEAKRHNWSIPDNLAVIGFDNQILSKITDPGITTMEQPIDDMARKVID
EECCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LMIDKIHTKNYRKKELYEFELELLVKGSTMKDAMLLA
HHHHHHHCCCCHHHHHHHHEEEHEEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]