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The map label for this gene is dhaK [H]

Identifier: 152974603

GI number: 152974603

Start: 901283

End: 903034

Strand: Direct

Name: dhaK [H]

Synonym: Bcer98_0787

Alternate gene names: 152974603

Gene position: 901283-903034 (Clockwise)

Preceding gene: 152974602

Following gene: 152974604

Centisome position: 22.05

GC content: 41.44

Gene sequence:

>1752_bases
ATGAAAAAAATTATAAATAAGCCGGAAACACTCGTCATGGAGATGTGCAATGGGATGGTCATGGCACATCCAGAACTTGA
GTTATTAAAAAAGTATAAAGTAATTAAGAAAAAAGAAATGAATGAAAATAAAGTTACATTAATTAGTGGTGGCGGAAGTG
GCCATGAACCAGCTCATGCTGGATTAGTTGGAAAAGGAATGCTAGATGCGGCAGTGTGCGGAGATGTGTTTGCTTCCCCT
TCACAAATTCAAGTGTATCAGGCCATTAAAGCAACAGCGAGCAAAAAAGGTACGCTCCTTATTATTAAAAACTACAGCGG
CGATATTATGAATTTTAAAAATGGTGCTCACTTAGCTACTGAGGATGGCATTCGAGTCGAATATGTTCGCGTAGATGATG
ATATTGCGGTAGAAGATAGCCTTTATACAGTTGGTCGCCGCGGTGTTGCTGGAGTCATACTTGTACATAAAATTGCCGGT
GCAGCAGCAGAAGAAGGTATGGATTTAATGCAGGTCAAAGCTATAGCGGAAAAAGCAGTGGCGAATGTTCGTACAATTGG
TATGGCGCTCACTTCTTGTACGGTTCCAGCTAGTGGTTCACCTACTTTCAAATTAGGTGAAGATGAGATGGAATACGGGG
TTGGTATTCACGGAGAGCCAGGAAGAAAACGTGAAAAAGTTATGAGCGCAGATGAGCTAGCAATGCGCATGACAAATGAT
CTTTTGAAAGATTTAGAGCTAGACGAAGAGACTGAAATTGCTGTTTTAGTGAACGGTTTTGGCGGTACACCGCTTCAAGA
ATTGTATGTATTTAACAATGCAGTTACGAGAGAACTAAGTAAACGAAACATACGAATCAATAGAACGTTTGTTGGTAACT
ATATGACAAGTATTGATATGGCTGGGCTTTCTTTAACTATTATGAAATTGGATAAAGAGCTAAAGACATTGTTATCGAAA
GAGTGTTATACGCCAGCGTTTCAAGTAGATGGTCTAGTGGAGAGGGTAGAATATATGCCTCTAGAGGAAGAGGAAGAAAA
ACAAGTTTCGTTTGAAGTAGAAACAGCGGAGAAACATGCGATAATTCAGAATGAGGTGCTTACGATAGACAATATGGTGT
ATCTTGTTGATAAAATGAGTGAAGTCATTATTCAAAATGAAATACCATTTTGTGAATTAGATACGCATGCGGGCGACGGA
GATTTTGGAATGAGCGTTGCGAAAGGATTCAAGCAATTGAAACGTGAATGGAGCTCGATTTTGAAACAAGAGCCTTTCAA
TATTGGAACATTTCTAGATGCGTGCTCTATGGTCATTATGGAACATTGCGGCGGTGCTTCTGGTCCAATTTGGGGCGGGG
CTTTTCGGGCTGCGAGTAAGGCTGCCGGAGAGCAAACAGAATTAACAGTTGGAGAAATGGCCAACATATTAGAAGCTTCC
TTAAAGGGTATACAATGGATTGGAGAGCGCTCTTTCGGACGAGGAGCTGAGGTAGGCGATAAAACACTTGTGGATGCATT
TGCACCTTGTGTACAGTCTTGGTTAGACAGTGCTACAAATGGTGTAGACTTTAAAACGGCTTTTGAAAAAGGAGCAGAGG
CTGCAGTGAAGGGGGCGGAATATACAAAAGAAATCGTTGCTCGAATGGGTCGTGCTGGTACAGTTGGAGAACGCAGCTTA
GGATATCCAGATGCCGGTGCCTATGCATTAGGAGTAATCTTTACGGAGCTTTCTCGTGCTTTAAGATCATAA

Upstream 100 bases:

>100_bases
TATGGAACGCGACAGGAATTTTCTATGAATTCATCTAATGATGTAAACATGTGAAGAATGATTTAGGAAAACAACAAAAC
GAATAAGGGTGGAATAGCAA

Downstream 100 bases:

>100_bases
TATAAAAGATTGTCTAAAACATGTATGAATTGCTTATATGTTATGTTCCAATTTTAATTTTCGTGTAATAATAAAGATAA
GAAATGCAAAAATATGATAG

Product: dihydroxyacetone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHAGLVGKGMLDAAVCGDVFASP
SQIQVYQAIKATASKKGTLLIIKNYSGDIMNFKNGAHLATEDGIRVEYVRVDDDIAVEDSLYTVGRRGVAGVILVHKIAG
AAAEEGMDLMQVKAIAEKAVANVRTIGMALTSCTVPASGSPTFKLGEDEMEYGVGIHGEPGRKREKVMSADELAMRMTND
LLKDLELDEETEIAVLVNGFGGTPLQELYVFNNAVTRELSKRNIRINRTFVGNYMTSIDMAGLSLTIMKLDKELKTLLSK
ECYTPAFQVDGLVERVEYMPLEEEEEKQVSFEVETAEKHAIIQNEVLTIDNMVYLVDKMSEVIIQNEIPFCELDTHAGDG
DFGMSVAKGFKQLKREWSSILKQEPFNIGTFLDACSMVIMEHCGGASGPIWGGAFRAASKAAGEQTELTVGEMANILEAS
LKGIQWIGERSFGRGAEVGDKTLVDAFAPCVQSWLDSATNGVDFKTAFEKGAEAAVKGAEYTKEIVARMGRAGTVGERSL
GYPDAGAYALGVIFTELSRALRS

Sequences:

>Translated_583_residues
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHAGLVGKGMLDAAVCGDVFASP
SQIQVYQAIKATASKKGTLLIIKNYSGDIMNFKNGAHLATEDGIRVEYVRVDDDIAVEDSLYTVGRRGVAGVILVHKIAG
AAAEEGMDLMQVKAIAEKAVANVRTIGMALTSCTVPASGSPTFKLGEDEMEYGVGIHGEPGRKREKVMSADELAMRMTND
LLKDLELDEETEIAVLVNGFGGTPLQELYVFNNAVTRELSKRNIRINRTFVGNYMTSIDMAGLSLTIMKLDKELKTLLSK
ECYTPAFQVDGLVERVEYMPLEEEEEKQVSFEVETAEKHAIIQNEVLTIDNMVYLVDKMSEVIIQNEIPFCELDTHAGDG
DFGMSVAKGFKQLKREWSSILKQEPFNIGTFLDACSMVIMEHCGGASGPIWGGAFRAASKAAGEQTELTVGEMANILEAS
LKGIQWIGERSFGRGAEVGDKTLVDAFAPCVQSWLDSATNGVDFKTAFEKGAEAAVKGAEYTKEIVARMGRAGTVGERSL
GYPDAGAYALGVIFTELSRALRS
>Mature_583_residues
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHAGLVGKGMLDAAVCGDVFASP
SQIQVYQAIKATASKKGTLLIIKNYSGDIMNFKNGAHLATEDGIRVEYVRVDDDIAVEDSLYTVGRRGVAGVILVHKIAG
AAAEEGMDLMQVKAIAEKAVANVRTIGMALTSCTVPASGSPTFKLGEDEMEYGVGIHGEPGRKREKVMSADELAMRMTND
LLKDLELDEETEIAVLVNGFGGTPLQELYVFNNAVTRELSKRNIRINRTFVGNYMTSIDMAGLSLTIMKLDKELKTLLSK
ECYTPAFQVDGLVERVEYMPLEEEEEKQVSFEVETAEKHAIIQNEVLTIDNMVYLVDKMSEVIIQNEIPFCELDTHAGDG
DFGMSVAKGFKQLKREWSSILKQEPFNIGTFLDACSMVIMEHCGGASGPIWGGAFRAASKAAGEQTELTVGEMANILEAS
LKGIQWIGERSFGRGAEVGDKTLVDAFAPCVQSWLDSATNGVDFKTAFEKGAEAAVKGAEYTKEIVARMGRAGTVGERSL
GYPDAGAYALGVIFTELSRALRS

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=581, Percent_Identity=32.7022375215146, Blast_Score=282, Evalue=6e-76,
Organism=Escherichia coli, GI87081857, Length=353, Percent_Identity=39.6600566572238, Blast_Score=265, Evalue=5e-72,
Organism=Escherichia coli, GI1787449, Length=191, Percent_Identity=31.413612565445, Blast_Score=86, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17565018, Length=592, Percent_Identity=31.9256756756757, Blast_Score=266, Evalue=3e-71,
Organism=Saccharomyces cerevisiae, GI6321055, Length=599, Percent_Identity=32.220367278798, Blast_Score=228, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6323570, Length=578, Percent_Identity=31.8339100346021, Blast_Score=215, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 63336; Mature: 63336

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHA
CCCCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
GLVGKGMLDAAVCGDVFASPSQIQVYQAIKATASKKGTLLIIKNYSGDIMNFKNGAHLAT
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCCCCEEE
EDGIRVEYVRVDDDIAVEDSLYTVGRRGVAGVILVHKIAGAAAEEGMDLMQVKAIAEKAV
CCCCEEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ANVRTIGMALTSCTVPASGSPTFKLGEDEMEYGVGIHGEPGRKREKVMSADELAMRMTND
HHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LLKDLELDEETEIAVLVNGFGGTPLQELYVFNNAVTRELSKRNIRINRTFVGNYMTSIDM
HHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHH
AGLSLTIMKLDKELKTLLSKECYTPAFQVDGLVERVEYMPLEEEEEKQVSFEVETAEKHA
CCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHH
IIQNEVLTIDNMVYLVDKMSEVIIQNEIPFCELDTHAGDGDFGMSVAKGFKQLKREWSSI
HHHCCEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
LKQEPFNIGTFLDACSMVIMEHCGGASGPIWGGAFRAASKAAGEQTELTVGEMANILEAS
HHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHH
LKGIQWIGERSFGRGAEVGDKTLVDAFAPCVQSWLDSATNGVDFKTAFEKGAEAAVKGAE
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHH
YTKEIVARMGRAGTVGERSLGYPDAGAYALGVIFTELSRALRS
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHA
CCCCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
GLVGKGMLDAAVCGDVFASPSQIQVYQAIKATASKKGTLLIIKNYSGDIMNFKNGAHLAT
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCCCCEEE
EDGIRVEYVRVDDDIAVEDSLYTVGRRGVAGVILVHKIAGAAAEEGMDLMQVKAIAEKAV
CCCCEEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
ANVRTIGMALTSCTVPASGSPTFKLGEDEMEYGVGIHGEPGRKREKVMSADELAMRMTND
HHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LLKDLELDEETEIAVLVNGFGGTPLQELYVFNNAVTRELSKRNIRINRTFVGNYMTSIDM
HHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHH
AGLSLTIMKLDKELKTLLSKECYTPAFQVDGLVERVEYMPLEEEEEKQVSFEVETAEKHA
CCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHH
IIQNEVLTIDNMVYLVDKMSEVIIQNEIPFCELDTHAGDGDFGMSVAKGFKQLKREWSSI
HHHCCEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
LKQEPFNIGTFLDACSMVIMEHCGGASGPIWGGAFRAASKAAGEQTELTVGEMANILEAS
HHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHH
LKGIQWIGERSFGRGAEVGDKTLVDAFAPCVQSWLDSATNGVDFKTAFEKGAEAAVKGAE
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHH
YTKEIVARMGRAGTVGERSLGYPDAGAYALGVIFTELSRALRS
HHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]