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The map label for this gene is bglH [H]

Identifier: 152974601

GI number: 152974601

Start: 898387

End: 899826

Strand: Direct

Name: bglH [H]

Synonym: Bcer98_0785

Alternate gene names: 152974601

Gene position: 898387-899826 (Clockwise)

Preceding gene: 152974600

Following gene: 152974602

Centisome position: 21.98

GC content: 36.67

Gene sequence:

>1440_bases
ATGGCTAAAGTTACGTTTCCAAAAGGTTTTTTATGGGGTGGGGCAATGGCTGCTAACCAAGCTGAAGGAGCATATTTAGA
AGATGGAAAAGGATTAACAACAGTGGATCTCCTTCCAACTGGTGAAAAACGTTGGGATATTATGAAAGGAAATATCCAAT
CCTTTACACCGATGGAAGGAGAATTTTATCCATCGCATGAAGCAATTGATTTTTACCATCGTTATAAAGAAGATATTGCT
CTGTTTGCAGAAATGGGATTTAAAGCGTTACGCGTTTCGATTGCGTGGACACGTATTTTTCCAAATGGTGACGAGAAACA
GCCAAATGAAACAGGTTTGCAGTTTTATGATAATTTGTTTGACGAATTATTGAAATATGGAATTGAGCCGGTCGTGACAA
TGGCTCATTTTGATGTACCTGTTCATTTAGTCGAAACATATGGAAGCTGGAGAAATCGAAAGCTTATCCATTTCTTTGAA
ACATATGCAAAAACGATTTTTAAACGATATAAAGATAAAGTGAAATATTGGATGACGTTTAATGAAATTAATATGCTACT
GCATTTACCTTTCGTTGGTGCTGGTTTAACTTTTAAAGAAGGCGAAAATAAAAAACAAATTCAATATCAAGCAGCACATC
ATCAGCTTGTGGCAAGTGCTTTAGCAGTGAAAGCGTGCCATGAAATAATACCGGATGCTAAAATTGGTTGTATGCTTGCA
GCAGGAGCGACGTATCCATATACATGCAATCCAGATGATGTTTTACGAGCGATGGAACAAGATAGAGAATCATTCTTTTT
CATTGATGTACAAGCAAGAGGTGAATATCCTGGATATGCGAAGCGATTCTTTAAAGATAATCACTTAGAGATTGAAATGG
AAAAAGAAGATGAAGAGATTTTAAAAGCATATACAGTGGATTATATTGGATTTAGCTACTATGCTAGCCGAGCAGCAAGT
ACAGACCCTGAAGTATTAAAGGGCATTACAAGTGGAAATGTATTTGGCTCTGTTGAAAATCCGTATCTTGAAAAATCAGA
ATGGGGCTGGACAATTGATCCAAAAGGGTTCCGTATTACAGCAAATCAACTGTACGATCGTTATCAGAAACCGCTGTTTG
TTGTGGAAAATGGTCTAGGTGCAATTGACACATTACATGCTGAAGAAGAGATTAACGATGAGTATCGCATCGATTATTTA
CGAAAACATATGATTGAACTTTCAGAGGCAATCCAAGATGGGGTAGAGGTTATTGGATATACAAGCTGGGGCCCAATTGA
CCTTGTCAGCGCTTCAACAGGTGAGATGAAGAAACGGTATGGATATATTTATGTTGATAAAGATAATGAAGGAAAAGGAT
CATTAAAAAGATTCAAAAAGAAAAGTTTTGATTGGTATAAACAAGTCATTGCAACAAACGGTGAAAGTTTAAACGCTTAA

Upstream 100 bases:

>100_bases
AGAAGTGAAATGATTTTTGAAATTTCATATTGTTTAAAACGAGGGAAGACATATTGCATGCCCTTCCTTCGTTAATTATT
ATATAAAGGAGTTTTCATAT

Downstream 100 bases:

>100_bases
ATCGTAAGAAAACCTGTGCCAAAAGGTCGTACAAAAGGCTCTTTTGGTGACAGGTTTTTCTTTTTTACACTATATGAATG
ATGCACGCTTCATTATCTGC

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MAKVTFPKGFLWGGAMAANQAEGAYLEDGKGLTTVDLLPTGEKRWDIMKGNIQSFTPMEGEFYPSHEAIDFYHRYKEDIA
LFAEMGFKALRVSIAWTRIFPNGDEKQPNETGLQFYDNLFDELLKYGIEPVVTMAHFDVPVHLVETYGSWRNRKLIHFFE
TYAKTIFKRYKDKVKYWMTFNEINMLLHLPFVGAGLTFKEGENKKQIQYQAAHHQLVASALAVKACHEIIPDAKIGCMLA
AGATYPYTCNPDDVLRAMEQDRESFFFIDVQARGEYPGYAKRFFKDNHLEIEMEKEDEEILKAYTVDYIGFSYYASRAAS
TDPEVLKGITSGNVFGSVENPYLEKSEWGWTIDPKGFRITANQLYDRYQKPLFVVENGLGAIDTLHAEEEINDEYRIDYL
RKHMIELSEAIQDGVEVIGYTSWGPIDLVSASTGEMKKRYGYIYVDKDNEGKGSLKRFKKKSFDWYKQVIATNGESLNA

Sequences:

>Translated_479_residues
MAKVTFPKGFLWGGAMAANQAEGAYLEDGKGLTTVDLLPTGEKRWDIMKGNIQSFTPMEGEFYPSHEAIDFYHRYKEDIA
LFAEMGFKALRVSIAWTRIFPNGDEKQPNETGLQFYDNLFDELLKYGIEPVVTMAHFDVPVHLVETYGSWRNRKLIHFFE
TYAKTIFKRYKDKVKYWMTFNEINMLLHLPFVGAGLTFKEGENKKQIQYQAAHHQLVASALAVKACHEIIPDAKIGCMLA
AGATYPYTCNPDDVLRAMEQDRESFFFIDVQARGEYPGYAKRFFKDNHLEIEMEKEDEEILKAYTVDYIGFSYYASRAAS
TDPEVLKGITSGNVFGSVENPYLEKSEWGWTIDPKGFRITANQLYDRYQKPLFVVENGLGAIDTLHAEEEINDEYRIDYL
RKHMIELSEAIQDGVEVIGYTSWGPIDLVSASTGEMKKRYGYIYVDKDNEGKGSLKRFKKKSFDWYKQVIATNGESLNA
>Mature_478_residues
AKVTFPKGFLWGGAMAANQAEGAYLEDGKGLTTVDLLPTGEKRWDIMKGNIQSFTPMEGEFYPSHEAIDFYHRYKEDIAL
FAEMGFKALRVSIAWTRIFPNGDEKQPNETGLQFYDNLFDELLKYGIEPVVTMAHFDVPVHLVETYGSWRNRKLIHFFET
YAKTIFKRYKDKVKYWMTFNEINMLLHLPFVGAGLTFKEGENKKQIQYQAAHHQLVASALAVKACHEIIPDAKIGCMLAA
GATYPYTCNPDDVLRAMEQDRESFFFIDVQARGEYPGYAKRFFKDNHLEIEMEKEDEEILKAYTVDYIGFSYYASRAAST
DPEVLKGITSGNVFGSVENPYLEKSEWGWTIDPKGFRITANQLYDRYQKPLFVVENGLGAIDTLHAEEEINDEYRIDYLR
KHMIELSEAIQDGVEVIGYTSWGPIDLVSASTGEMKKRYGYIYVDKDNEGKGSLKRFKKKSFDWYKQVIATNGESLNA

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=489, Percent_Identity=29.8568507157464, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI110681710, Length=496, Percent_Identity=30.0403225806452, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI13273313, Length=490, Percent_Identity=26.3265306122449, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI28376633, Length=492, Percent_Identity=27.6422764227642, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI24497614, Length=493, Percent_Identity=27.5862068965517, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1789070, Length=473, Percent_Identity=61.3107822410148, Blast_Score=624, Evalue=1e-180,
Organism=Escherichia coli, GI2367270, Length=478, Percent_Identity=57.5313807531381, Blast_Score=566, Evalue=1e-163,
Organism=Escherichia coli, GI2367174, Length=483, Percent_Identity=53.2091097308489, Blast_Score=527, Evalue=1e-151,
Organism=Caenorhabditis elegans, GI17552856, Length=483, Percent_Identity=29.399585921325, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17539390, Length=477, Percent_Identity=28.3018867924528, Blast_Score=164, Evalue=8e-41,
Organism=Drosophila melanogaster, GI21356577, Length=498, Percent_Identity=26.5060240963855, Blast_Score=139, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54974; Mature: 54843

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVTFPKGFLWGGAMAANQAEGAYLEDGKGLTTVDLLPTGEKRWDIMKGNIQSFTPMEG
CCEECCCCCCEECCCCCCCCCCCCEEECCCCCEEEEEECCCCCCCEEECCCCCCCCCCCC
EFYPSHEAIDFYHRYKEDIALFAEMGFKALRVSIAWTRIFPNGDEKQPNETGLQFYDNLF
CCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHH
DELLKYGIEPVVTMAHFDVPVHLVETYGSWRNRKLIHFFETYAKTIFKRYKDKVKYWMTF
HHHHHCCCCCEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEE
NEINMLLHLPFVGAGLTFKEGENKKQIQYQAAHHQLVASALAVKACHEIIPDAKIGCMLA
HHEEEEEECCEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
AGATYPYTCNPDDVLRAMEQDRESFFFIDVQARGEYPGYAKRFFKDNHLEIEMEKEDEEI
ECCCCCCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHCCCCCEEEEECCCHHHH
LKAYTVDYIGFSYYASRAASTDPEVLKGITSGNVFGSVENPYLEKSEWGWTIDPKGFRIT
HHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEECCCCCCCCCCCCCEEECCCCCEEE
ANQLYDRYQKPLFVVENGLGAIDTLHAEEEINDEYRIDYLRKHMIELSEAIQDGVEVIGY
HHHHHHHHCCCEEEEECCCCCHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHCCHHEEEE
TSWGPIDLVSASTGEMKKRYGYIYVDKDNEGKGSLKRFKKKSFDWYKQVIATNGESLNA
CCCCCEEEEECCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKVTFPKGFLWGGAMAANQAEGAYLEDGKGLTTVDLLPTGEKRWDIMKGNIQSFTPMEG
CEECCCCCCEECCCCCCCCCCCCEEECCCCCEEEEEECCCCCCCEEECCCCCCCCCCCC
EFYPSHEAIDFYHRYKEDIALFAEMGFKALRVSIAWTRIFPNGDEKQPNETGLQFYDNLF
CCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHH
DELLKYGIEPVVTMAHFDVPVHLVETYGSWRNRKLIHFFETYAKTIFKRYKDKVKYWMTF
HHHHHCCCCCEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEE
NEINMLLHLPFVGAGLTFKEGENKKQIQYQAAHHQLVASALAVKACHEIIPDAKIGCMLA
HHEEEEEECCEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
AGATYPYTCNPDDVLRAMEQDRESFFFIDVQARGEYPGYAKRFFKDNHLEIEMEKEDEEI
ECCCCCCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHCCCCCEEEEECCCHHHH
LKAYTVDYIGFSYYASRAASTDPEVLKGITSGNVFGSVENPYLEKSEWGWTIDPKGFRIT
HHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEECCCCCCCCCCCCCEEECCCCCEEE
ANQLYDRYQKPLFVVENGLGAIDTLHAEEEINDEYRIDYLRKHMIELSEAIQDGVEVIGY
HHHHHHHHCCCEEEEECCCCCHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHCCHHEEEE
TSWGPIDLVSASTGEMKKRYGYIYVDKDNEGKGSLKRFKKKSFDWYKQVIATNGESLNA
CCCCCEEEEECCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377 [H]