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The map label for this gene is rbsK [H]

Identifier: 152974387

GI number: 152974387

Start: 640432

End: 641328

Strand: Direct

Name: rbsK [H]

Synonym: Bcer98_0560

Alternate gene names: 152974387

Gene position: 640432-641328 (Clockwise)

Preceding gene: 152974386

Following gene: 152974388

Centisome position: 15.67

GC content: 41.36

Gene sequence:

>897_bases
TTGCCAAATATAGCTGTAGTAGGGAGTATTTCAATGGATTTAGTAGCCGTTTCAAAGAAAAGACCGAAAGCTGGAGAAAC
AGTAATCGGAGAGGCGTTTCATACAGTACCTGGAGGAAAAGGAGCAAATCAGGCTGTTGCCGCAGCTCGCTTAGGGGCCA
ATGTAGCTATGGTAGGTGCTGTAGGGAATGATGATTACGGCATGAGTGTACGAAAAAATTTAGAGAACGAGCGTGTTTTT
ATCGATCATGTGGTACCGGTTACAGATGAAACAACAGGCATTGCTCATATCGTTTTAGCAGAAGAAGATAATAGCATTGT
TGTTGTGCAAGGTGCCAATCGCCTTGTGAATCAGCAAATTGTTGACCGTGCAAAAGATTTACTTGTAAAGGCAGATATGG
TCGTTCTTCAGTTAGAAATTCCGCTTGAGACAGTAGAATATGTGCTTACTATTTGTGAGGAGCATAAGATCCCAGTCATG
TTAAATCCAGCTCCAGCACAAGCATTATCGACAAGGATTTTGGAAAAGGCAACATATATTACACCGAATGAACACGAGTG
TCGCATTGTACTAGATGATTTTGAATCACCGATTGAAGACTTACTTGCTAAATATCCAAATAAATTATTAATGACAGAAG
GAAGTAAAGGAGTTCGATTCCATAATGGTACAGAAATTGTACAAGTGCCAAGTATTTCTGTAAAAGTAGTTGACACGACA
GGGGCTGGTGATACATTTAACGGGGCATTAGCAGTTTCGCTTGCAGAAGGAGAAGTGCTTGAAAAAGCAATTCGTTTTGC
AAATATAGCCGGTGGCCTTTCTGTAACAAAGCTCGGTGCACAAGGTGGTATGCCAACAAGAGAACAGGTGCGGGAAGTAC
AGGGGATTGTTAAATGA

Upstream 100 bases:

>100_bases
TTATTAGAACAAATGGAAGGAAAACGGTTAGAAACAGAACATTACCGTTTGCCGATTGAAATTATCGAACGAAATACAAC
GAAATAAGGAGATGAAGTCG

Downstream 100 bases:

>100_bases
AAAAGCATGGCGTATTAAATAGTGAAATTGCTGCTATATTAGCGGCACTTGGTCATACAGATACGATTGTAATCGCGGAC
TGCGGATTACCAATTCCTGA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MPNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTVPGGKGANQAVAAARLGANVAMVGAVGNDDYGMSVRKNLENERVF
IDHVVPVTDETTGIAHIVLAEEDNSIVVVQGANRLVNQQIVDRAKDLLVKADMVVLQLEIPLETVEYVLTICEEHKIPVM
LNPAPAQALSTRILEKATYITPNEHECRIVLDDFESPIEDLLAKYPNKLLMTEGSKGVRFHNGTEIVQVPSISVKVVDTT
GAGDTFNGALAVSLAEGEVLEKAIRFANIAGGLSVTKLGAQGGMPTREQVREVQGIVK

Sequences:

>Translated_298_residues
MPNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTVPGGKGANQAVAAARLGANVAMVGAVGNDDYGMSVRKNLENERVF
IDHVVPVTDETTGIAHIVLAEEDNSIVVVQGANRLVNQQIVDRAKDLLVKADMVVLQLEIPLETVEYVLTICEEHKIPVM
LNPAPAQALSTRILEKATYITPNEHECRIVLDDFESPIEDLLAKYPNKLLMTEGSKGVRFHNGTEIVQVPSISVKVVDTT
GAGDTFNGALAVSLAEGEVLEKAIRFANIAGGLSVTKLGAQGGMPTREQVREVQGIVK
>Mature_297_residues
PNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTVPGGKGANQAVAAARLGANVAMVGAVGNDDYGMSVRKNLENERVFI
DHVVPVTDETTGIAHIVLAEEDNSIVVVQGANRLVNQQIVDRAKDLLVKADMVVLQLEIPLETVEYVLTICEEHKIPVML
NPAPAQALSTRILEKATYITPNEHECRIVLDDFESPIEDLLAKYPNKLLMTEGSKGVRFHNGTEIVQVPSISVKVVDTTG
AGDTFNGALAVSLAEGEVLEKAIRFANIAGGLSVTKLGAQGGMPTREQVREVQGIVK

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=35.1351351351351, Blast_Score=144, Evalue=6e-35,
Organism=Escherichia coli, GI1790193, Length=296, Percent_Identity=38.8513513513513, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI87082343, Length=309, Percent_Identity=29.7734627831715, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789432, Length=291, Percent_Identity=29.8969072164948, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788491, Length=277, Percent_Identity=24.5487364620939, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87081971, Length=277, Percent_Identity=23.826714801444, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=300, Percent_Identity=36.3333333333333, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI25147470, Length=306, Percent_Identity=23.5294117647059, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6319884, Length=331, Percent_Identity=32.6283987915408, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6322565, Length=270, Percent_Identity=28.5185185185185, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20128807, Length=300, Percent_Identity=36.3333333333333, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24583886, Length=308, Percent_Identity=29.2207792207792, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31790; Mature: 31659

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTVPGGKGANQAVAAARLGANVAMVGA
CCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEE
VGNDDYGMSVRKNLENERVFIDHVVPVTDETTGIAHIVLAEEDNSIVVVQGANRLVNQQI
ECCCCCCCHHHHCCCCCEEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCHHHHHHH
VDRAKDLLVKADMVVLQLEIPLETVEYVLTICEEHKIPVMLNPAPAQALSTRILEKATYI
HHHHHHHHEEECEEEEEEECCHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCC
TPNEHECRIVLDDFESPIEDLLAKYPNKLLMTEGSKGVRFHNGTEIVQVPSISVKVVDTT
CCCCCCEEEEECCCCCHHHHHHHHCCCEEEEECCCCCCEEECCCEEEEECCEEEEEEEEC
GAGDTFNGALAVSLAEGEVLEKAIRFANIAGGLSVTKLGAQGGMPTREQVREVQGIVK
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
PNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTVPGGKGANQAVAAARLGANVAMVGA
CCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEE
VGNDDYGMSVRKNLENERVFIDHVVPVTDETTGIAHIVLAEEDNSIVVVQGANRLVNQQI
ECCCCCCCHHHHCCCCCEEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCHHHHHHH
VDRAKDLLVKADMVVLQLEIPLETVEYVLTICEEHKIPVMLNPAPAQALSTRILEKATYI
HHHHHHHHEEECEEEEEEECCHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCC
TPNEHECRIVLDDFESPIEDLLAKYPNKLLMTEGSKGVRFHNGTEIVQVPSISVKVVDTT
CCCCCCEEEEECCCCCHHHHHHHHCCCEEEEECCCCCCEEECCCEEEEECCEEEEEEEEC
GAGDTFNGALAVSLAEGEVLEKAIRFANIAGGLSVTKLGAQGGMPTREQVREVQGIVK
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]