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The map label for this gene is yusP [H]

Identifier: 152974385

GI number: 152974385

Start: 637694

End: 639310

Strand: Direct

Name: yusP [H]

Synonym: Bcer98_0558

Alternate gene names: 152974385

Gene position: 637694-639310 (Clockwise)

Preceding gene: 152974384

Following gene: 152974386

Centisome position: 15.6

GC content: 37.35

Gene sequence:

>1617_bases
ATGAAACAACAGGGTGGTAAAAAAAGGGGATTATTGTTGGTTGGTTTAGTGATTGCGATATTATTTGCAGCGTTAGATGG
AACAATCGTCGGTACAGCGATGCCGCGTATTGTCGGCGAACTAGGTGGATTAAGCTTAATGACATGGCTAGTAACAGCTT
ACATGCTAACATCTACGACAATTGTACCGATTGCAGGTAAATTAGCGGATTTATTAGGACGCCGTAACGTATATATGACA
GGATTAATTATCTTTATGATTGGTTCAGCATTATGTGGTATGGCAAATGGTATGACAGAATTGATTATTTTCCGCGGTAT
TCAAGGTCTTGGCGGAGGTATTATGATGCCGATGGCTATGATTATTATTGGAGATATGTTCACGGGGAAAGAGCGTGCGA
AATGGCAAGGTATTGTTGGCGCTTTATATGGTCTTGCTTCAGTCATTGGTCCGCAAGTTGGTGGTTGGATTGTAGATGCA
GTTAACTGGAGATGGGTGTTTTACATTAACTTACCAGTTGGTATTGTCGCAACAATCTTTATTGCGATGGGATTACACTC
ACATAAGCAAACAGGACCTATTAAAATTGACATTGCTGGAATTTTTACGATGATTGTTGGAGTTGTAAGTTTATTACTTG
CATTAACATTCGGCGGAAAAGATTACGCATGGGATTCTTGGCAAATTATCGGATTGTTTAGTTTAGCTTTAATTGGTATT
GTAAGCTTTGTATTTGTGGAAACAAAAGCTGAGGAACCAATCTTACCGATGCATTTCTTTAAAAATCGTACATTTACACT
ATTGAATGCGATTGGTTTCTTTATGAGTATTGGAATGTTTGGTGCAATTATGTTCGTTCCATTCTTTATGCAAGGAATTG
TAGGAGTAAGTGCAGCTGAATCTGGGACGATTATGACACCGATGATGATTACAATGATTGTGACGAGTATTATTGGTGGT
CGACTTGTCTTAAAAGTTGGCGTGAAGCCGCAGATTATTGTTGGTATGTTGATTATGGCTGGTGGCTTCTGGTTATTAAC
AACAATGGATATGCATACAAGCAAGCTTGTAGCGACTTCTTATATGATCATTATCGGTTTAGGTGTGGGGCTTGTAATGC
CAACATTGACATTGGCATTACAAGAAAGTTTCCCGAAAAAGAATCTTGGTGTTGTAACCTCATCCAGTCAATTTTTTCGG
CAAATTGGAGGAACATTTGGAATTACAATCTTAGGATCCATTATGAATAATACTTCAAGCACCATTTTAACTGAAAAATT
AGTACCCGTATTAGAGAAGTTTCCACCACAAGCTGGACAGATTGTAACAAAATTTAAAGATATGATTCATACAGATCCAC
AAGGGTTATATTCTATGCTGTTTAGTCCAGAGGTATTGAAAAAAATGCCAGAAGTATTTTCTACAAGTATCGTTCCTATT
TTGAAGAATTCGTTATTGGATTCATTGCATAGTGTATTTTTAGCGGGATTAGTATTTACTGTTGTTGGTGCTATCTTTAC
GATTTTCTTAGAGAAGATTAAGCTTTCTGATCGAAAGAAAGGTGCAGAAGAGGTAGTAGAAGGAGAAGAGAAACATACAA
ATGGATCCTATTCATAA

Upstream 100 bases:

>100_bases
GAAAGAAAAGACTTATTACGCCTGTTTGAAAAATTAGAAACAATTGTTTGCGGGACAAATGAGAAAAAAGAGCTAATTTA
AGAGAAGGTGAGGAGATTAT

Downstream 100 bases:

>100_bases
TAAAAGCATCGCCTTATGGTGATGCTTTTATTATATGTATAACATATACTCTTTTTGAGTAGAAATGATTGACGTATTTT
TGCGAATAGGTTATATTACT

Product: EmrB/QacA family drug resistance transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MKQQGGKKRGLLLVGLVIAILFAALDGTIVGTAMPRIVGELGGLSLMTWLVTAYMLTSTTIVPIAGKLADLLGRRNVYMT
GLIIFMIGSALCGMANGMTELIIFRGIQGLGGGIMMPMAMIIIGDMFTGKERAKWQGIVGALYGLASVIGPQVGGWIVDA
VNWRWVFYINLPVGIVATIFIAMGLHSHKQTGPIKIDIAGIFTMIVGVVSLLLALTFGGKDYAWDSWQIIGLFSLALIGI
VSFVFVETKAEEPILPMHFFKNRTFTLLNAIGFFMSIGMFGAIMFVPFFMQGIVGVSAAESGTIMTPMMITMIVTSIIGG
RLVLKVGVKPQIIVGMLIMAGGFWLLTTMDMHTSKLVATSYMIIIGLGVGLVMPTLTLALQESFPKKNLGVVTSSSQFFR
QIGGTFGITILGSIMNNTSSTILTEKLVPVLEKFPPQAGQIVTKFKDMIHTDPQGLYSMLFSPEVLKKMPEVFSTSIVPI
LKNSLLDSLHSVFLAGLVFTVVGAIFTIFLEKIKLSDRKKGAEEVVEGEEKHTNGSYS

Sequences:

>Translated_538_residues
MKQQGGKKRGLLLVGLVIAILFAALDGTIVGTAMPRIVGELGGLSLMTWLVTAYMLTSTTIVPIAGKLADLLGRRNVYMT
GLIIFMIGSALCGMANGMTELIIFRGIQGLGGGIMMPMAMIIIGDMFTGKERAKWQGIVGALYGLASVIGPQVGGWIVDA
VNWRWVFYINLPVGIVATIFIAMGLHSHKQTGPIKIDIAGIFTMIVGVVSLLLALTFGGKDYAWDSWQIIGLFSLALIGI
VSFVFVETKAEEPILPMHFFKNRTFTLLNAIGFFMSIGMFGAIMFVPFFMQGIVGVSAAESGTIMTPMMITMIVTSIIGG
RLVLKVGVKPQIIVGMLIMAGGFWLLTTMDMHTSKLVATSYMIIIGLGVGLVMPTLTLALQESFPKKNLGVVTSSSQFFR
QIGGTFGITILGSIMNNTSSTILTEKLVPVLEKFPPQAGQIVTKFKDMIHTDPQGLYSMLFSPEVLKKMPEVFSTSIVPI
LKNSLLDSLHSVFLAGLVFTVVGAIFTIFLEKIKLSDRKKGAEEVVEGEEKHTNGSYS
>Mature_538_residues
MKQQGGKKRGLLLVGLVIAILFAALDGTIVGTAMPRIVGELGGLSLMTWLVTAYMLTSTTIVPIAGKLADLLGRRNVYMT
GLIIFMIGSALCGMANGMTELIIFRGIQGLGGGIMMPMAMIIIGDMFTGKERAKWQGIVGALYGLASVIGPQVGGWIVDA
VNWRWVFYINLPVGIVATIFIAMGLHSHKQTGPIKIDIAGIFTMIVGVVSLLLALTFGGKDYAWDSWQIIGLFSLALIGI
VSFVFVETKAEEPILPMHFFKNRTFTLLNAIGFFMSIGMFGAIMFVPFFMQGIVGVSAAESGTIMTPMMITMIVTSIIGG
RLVLKVGVKPQIIVGMLIMAGGFWLLTTMDMHTSKLVATSYMIIIGLGVGLVMPTLTLALQESFPKKNLGVVTSSSQFFR
QIGGTFGITILGSIMNNTSSTILTEKLVPVLEKFPPQAGQIVTKFKDMIHTDPQGLYSMLFSPEVLKKMPEVFSTSIVPI
LKNSLLDSLHSVFLAGLVFTVVGAIFTIFLEKIKLSDRKKGAEEVVEGEEKHTNGSYS

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1789042, Length=469, Percent_Identity=27.7185501066098, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1788710, Length=447, Percent_Identity=26.6219239373602, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI87081983, Length=413, Percent_Identity=24.9394673123487, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790195, Length=352, Percent_Identity=28.6931818181818, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788392, Length=289, Percent_Identity=30.1038062283737, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790146, Length=188, Percent_Identity=26.063829787234, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322958, Length=579, Percent_Identity=25.73402417962, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6323735, Length=545, Percent_Identity=23.6697247706422, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6319770, Length=407, Percent_Identity=24.8157248157248, Blast_Score=123, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6321663, Length=554, Percent_Identity=24.3682310469314, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319783, Length=489, Percent_Identity=25.1533742331288, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6325455, Length=411, Percent_Identity=25.3041362530414, Blast_Score=100, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6324954, Length=381, Percent_Identity=23.6220472440945, Blast_Score=90, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6323520, Length=365, Percent_Identity=25.4794520547945, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 58008; Mature: 58008

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQQGGKKRGLLLVGLVIAILFAALDGTIVGTAMPRIVGELGGLSLMTWLVTAYMLTSTT
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCH
IVPIAGKLADLLGRRNVYMTGLIIFMIGSALCGMANGMTELIIFRGIQGLGGGIMMPMAM
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHH
IIIGDMFTGKERAKWQGIVGALYGLASVIGPQVGGWIVDAVNWRWVFYINLPVGIVATIF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEEECCHHHHHHHH
IAMGLHSHKQTGPIKIDIAGIFTMIVGVVSLLLALTFGGKDYAWDSWQIIGLFSLALIGI
HHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
VSFVFVETKAEEPILPMHFFKNRTFTLLNAIGFFMSIGMFGAIMFVPFFMQGIVGVSAAE
HHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SGTIMTPMMITMIVTSIIGGRLVLKVGVKPQIIVGMLIMAGGFWLLTTMDMHTSKLVATS
CCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHH
YMIIIGLGVGLVMPTLTLALQESFPKKNLGVVTSSSQFFRQIGGTFGITILGSIMNNTSS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHCCCHHHHHHHHHHCCCHH
TILTEKLVPVLEKFPPQAGQIVTKFKDMIHTDPQGLYSMLFSPEVLKKMPEVFSTSIVPI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LKNSLLDSLHSVFLAGLVFTVVGAIFTIFLEKIKLSDRKKGAEEVVEGEEKHTNGSYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKQQGGKKRGLLLVGLVIAILFAALDGTIVGTAMPRIVGELGGLSLMTWLVTAYMLTSTT
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCH
IVPIAGKLADLLGRRNVYMTGLIIFMIGSALCGMANGMTELIIFRGIQGLGGGIMMPMAM
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHH
IIIGDMFTGKERAKWQGIVGALYGLASVIGPQVGGWIVDAVNWRWVFYINLPVGIVATIF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEEECCHHHHHHHH
IAMGLHSHKQTGPIKIDIAGIFTMIVGVVSLLLALTFGGKDYAWDSWQIIGLFSLALIGI
HHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
VSFVFVETKAEEPILPMHFFKNRTFTLLNAIGFFMSIGMFGAIMFVPFFMQGIVGVSAAE
HHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SGTIMTPMMITMIVTSIIGGRLVLKVGVKPQIIVGMLIMAGGFWLLTTMDMHTSKLVATS
CCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHH
YMIIIGLGVGLVMPTLTLALQESFPKKNLGVVTSSSQFFRQIGGTFGITILGSIMNNTSS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHCCCHHHHHHHHHHCCCHH
TILTEKLVPVLEKFPPQAGQIVTKFKDMIHTDPQGLYSMLFSPEVLKKMPEVFSTSIVPI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LKNSLLDSLHSVFLAGLVFTVVGAIFTIFLEKIKLSDRKKGAEEVVEGEEKHTNGSYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]