Click here to switch to the map view.

The map label for this gene is yrkA [H]

Identifier: 152974355

GI number: 152974355

Start: 599621

End: 600946

Strand: Direct

Name: yrkA [H]

Synonym: Bcer98_0525

Alternate gene names: 152974355

Gene position: 599621-600946 (Clockwise)

Preceding gene: 152974352

Following gene: 152974356

Centisome position: 14.67

GC content: 36.35

Gene sequence:

>1326_bases
GTGGGAATTTTAAAATTACTTATGGTTGCTATTTTAATTGCTTTAACAGCCTTTTTTGTTGCCGTTGAATTTGCTATTAT
AAAGGTGAGAAGTAGTCGTATCGATCAACTTGTAATCGAAAAAAGACGAGGGGCATTAGCGGCGAAGAAAGTCACTTCGA
ATTTAGATGAATACTTATCCGCTTGTCAGCTTGGAATTACAATTACAGCTTTAGGATTAGGGTGGTTAGGTGAACCGACA
GTTAAACATATGTTAGAGCCATTATTTTTGAGAATGAATATTTCATCAGTAGCTGCAAGTACAGTATCATTTATTATTGC
ATTTGCAGTCATCACATTTCTGCACGTCGTTGCTGGAGAGCTGGCTCCAAAAACGTTTGCGATTCAAAAAGCAGAAAAAG
TTAGCTTGTTACTGTCACAGCCTCTTATTTATTTCTATCGGATTATGTACCCCTTTATTTGGGCTTTAAATGGGTCTTCA
CGCTTTGTGACAGGAATATTTGGACTTCAACCTGCTTCTGAACATGATGTGGTACATTCAGAGGAAGAATTGCGTCTCAT
TTTATCGGAAAGTTATGAGCGAGGGGAGATTAATCAAGCAGAATTTAAGTATGTAAATAACATTTTTGAATTTGACAATC
GATTAGCGAAAGAGATTATGGTTCCCCGTACGGAAATTGTAGGATTATATGAAGATGAACCATTTGAGACGCATATTCAA
ATTATTAGACAGGAAAAATATACAAGATATCCCGTATTTGGAGAAGATAAAGATGAAATTATTGGGATGGTGAATGTAAA
AGATTTATTCATTCGCTATATGGATGGAGGACGAGAGGAAGAATGTTCTATTACGCCGTATACAAGACCTGTCATTGAAG
TGTTAGAAAACATTCCGATTCACGATTTGTTGTTACAGATGCAAAAGCGAAGAATTCCAATGGCTGTTTTATATGATGAG
TATGGCGGGACGGCTGGTATTGTAACTCTTGAAGACATTCTAGAGGAAATTGTTGGGGAAATTCGAGATGAGTATGATGA
GGATGAATATCCACCAATAGAGCACATAAGTGAAACATGGAAAATTGTAGATGGAAAAGTACGTATTAGCGAAGTAAATG
ATTTATTTGGACTACAGCTATTAGCGAATGATGTCGATACAATCGGTGGCTGGATTATGATGCAGAAACAAACGATTACA
GAAGGGGATTATATTGAAACAAATGGATTAGTATTCAAAGTCCTGGAAAAAGACATGCATCAAATAAAACGAGTAGAAAT
TATGAGAAAAGAAGAAAAAGGGGCGTTTAAGGAGAGGAAGGATTAG

Upstream 100 bases:

>100_bases
GGAATTTTATCTAGATTTGCTTTTCAATAAATGAAGAAACTAAAGGAAAACTTCTTTTAAAAAGGAGGTGTAACTTTAGC
GAGAAAGCTAAAGGATTTTG

Downstream 100 bases:

>100_bases
ATAAAGTGAAACTTTAATCAGTGGGGGCTTCATCCCCTACTGATTATGAGCCCTCACCAATCGGGCTGCCCTAAAATAGC
GGGATAAAAAACATAATGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MGILKLLMVAILIALTAFFVAVEFAIIKVRSSRIDQLVIEKRRGALAAKKVTSNLDEYLSACQLGITITALGLGWLGEPT
VKHMLEPLFLRMNISSVAASTVSFIIAFAVITFLHVVAGELAPKTFAIQKAEKVSLLLSQPLIYFYRIMYPFIWALNGSS
RFVTGIFGLQPASEHDVVHSEEELRLILSESYERGEINQAEFKYVNNIFEFDNRLAKEIMVPRTEIVGLYEDEPFETHIQ
IIRQEKYTRYPVFGEDKDEIIGMVNVKDLFIRYMDGGREEECSITPYTRPVIEVLENIPIHDLLLQMQKRRIPMAVLYDE
YGGTAGIVTLEDILEEIVGEIRDEYDEDEYPPIEHISETWKIVDGKVRISEVNDLFGLQLLANDVDTIGGWIMMQKQTIT
EGDYIETNGLVFKVLEKDMHQIKRVEIMRKEEKGAFKERKD

Sequences:

>Translated_441_residues
MGILKLLMVAILIALTAFFVAVEFAIIKVRSSRIDQLVIEKRRGALAAKKVTSNLDEYLSACQLGITITALGLGWLGEPT
VKHMLEPLFLRMNISSVAASTVSFIIAFAVITFLHVVAGELAPKTFAIQKAEKVSLLLSQPLIYFYRIMYPFIWALNGSS
RFVTGIFGLQPASEHDVVHSEEELRLILSESYERGEINQAEFKYVNNIFEFDNRLAKEIMVPRTEIVGLYEDEPFETHIQ
IIRQEKYTRYPVFGEDKDEIIGMVNVKDLFIRYMDGGREEECSITPYTRPVIEVLENIPIHDLLLQMQKRRIPMAVLYDE
YGGTAGIVTLEDILEEIVGEIRDEYDEDEYPPIEHISETWKIVDGKVRISEVNDLFGLQLLANDVDTIGGWIMMQKQTIT
EGDYIETNGLVFKVLEKDMHQIKRVEIMRKEEKGAFKERKD
>Mature_440_residues
GILKLLMVAILIALTAFFVAVEFAIIKVRSSRIDQLVIEKRRGALAAKKVTSNLDEYLSACQLGITITALGLGWLGEPTV
KHMLEPLFLRMNISSVAASTVSFIIAFAVITFLHVVAGELAPKTFAIQKAEKVSLLLSQPLIYFYRIMYPFIWALNGSSR
FVTGIFGLQPASEHDVVHSEEELRLILSESYERGEINQAEFKYVNNIFEFDNRLAKEIMVPRTEIVGLYEDEPFETHIQI
IRQEKYTRYPVFGEDKDEIIGMVNVKDLFIRYMDGGREEECSITPYTRPVIEVLENIPIHDLLLQMQKRRIPMAVLYDEY
GGTAGIVTLEDILEEIVGEIRDEYDEDEYPPIEHISETWKIVDGKVRISEVNDLFGLQLLANDVDTIGGWIMMQKQTITE
GDYIETNGLVFKVLEKDMHQIKRVEIMRKEEKGAFKERKD

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=405, Percent_Identity=46.4197530864198, Blast_Score=374, Evalue=1e-104,
Organism=Escherichia coli, GI1790664, Length=435, Percent_Identity=22.9885057471264, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI145693175, Length=381, Percent_Identity=25.1968503937008, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1786879, Length=252, Percent_Identity=31.3492063492063, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI87082033, Length=241, Percent_Identity=25.3112033195021, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788119, Length=240, Percent_Identity=25.4166666666667, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50456; Mature: 50325

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGILKLLMVAILIALTAFFVAVEFAIIKVRSSRIDQLVIEKRRGALAAKKVTSNLDEYLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
ACQLGITITALGLGWLGEPTVKHMLEPLFLRMNISSVAASTVSFIIAFAVITFLHVVAGE
HHHHCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAPKTFAIQKAEKVSLLLSQPLIYFYRIMYPFIWALNGSSRFVTGIFGLQPASEHDVVHS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCCCCCCCCCC
EEELRLILSESYERGEINQAEFKYVNNIFEFDNRLAKEIMVPRTEIVGLYEDEPFETHIQ
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHH
IIRQEKYTRYPVFGEDKDEIIGMVNVKDLFIRYMDGGREEECSITPYTRPVIEVLENIPI
HHHHHCCCCCCCCCCCHHHEEEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCH
HDLLLQMQKRRIPMAVLYDEYGGTAGIVTLEDILEEIVGEIRDEYDEDEYPPIEHISETW
HHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
KIVDGKVRISEVNDLFGLQLLANDVDTIGGWIMMQKQTITEGDYIETNGLVFKVLEKDMH
HHCCCEEEEEHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEECCCHHHHHHHHHHH
QIKRVEIMRKEEKGAFKERKD
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GILKLLMVAILIALTAFFVAVEFAIIKVRSSRIDQLVIEKRRGALAAKKVTSNLDEYLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
ACQLGITITALGLGWLGEPTVKHMLEPLFLRMNISSVAASTVSFIIAFAVITFLHVVAGE
HHHHCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAPKTFAIQKAEKVSLLLSQPLIYFYRIMYPFIWALNGSSRFVTGIFGLQPASEHDVVHS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCCCCCCCCCC
EEELRLILSESYERGEINQAEFKYVNNIFEFDNRLAKEIMVPRTEIVGLYEDEPFETHIQ
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHH
IIRQEKYTRYPVFGEDKDEIIGMVNVKDLFIRYMDGGREEECSITPYTRPVIEVLENIPI
HHHHHCCCCCCCCCCCHHHEEEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCH
HDLLLQMQKRRIPMAVLYDEYGGTAGIVTLEDILEEIVGEIRDEYDEDEYPPIEHISETW
HHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
KIVDGKVRISEVNDLFGLQLLANDVDTIGGWIMMQKQTITEGDYIETNGLVFKVLEKDMH
HHCCCEEEEEHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEECCCHHHHHHHHHHH
QIKRVEIMRKEEKGAFKERKD
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377; 8969508; 7608059 [H]