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The map label for this gene is perR [H]

Identifier: 152974292

GI number: 152974292

Start: 514328

End: 514759

Strand: Direct

Name: perR [H]

Synonym: Bcer98_0459

Alternate gene names: 152974292

Gene position: 514328-514759 (Clockwise)

Preceding gene: 152974291

Following gene: 152974294

Centisome position: 12.58

GC content: 35.42

Gene sequence:

>432_bases
GTGGTCAAAGAAGAATTAAAAGAAGCGCTAGAAATGCTAAAAAATACGGGTGTACGAATTACTCCACAGCGTCATGCTAT
TTTAGAGTACCTTGTGGAATCTATGACACACCCAACGGCGGATGAAATTTATAAAGCATTAGAAGGTAAGTTTCCAAATA
TGAGTGTTGCAACTGTTTATAATAATTTACGTGTATTTAAAGAAGTAGGACTTGTAAAGGAATTAACTTACGGAGACGCT
TCAAGTAGATTTGATTATGTTACAAGTCAACATTATCATGTGATTTGCGAGAAATGTGGTAAGATTGTTGATTTTCCTTA
TGAAGGTTTGGAAAAGCTTGAAGATGAAGCTGCAAAAACAACGGGCTTCGTTATTAATAGTCATCGCTTAGAGATTTATG
GTGTATGTCCAGAATGTCATAAGGCGCAATAA

Upstream 100 bases:

>100_bases
ATCTAGTTATAGTAGAAATATTGACGATTGATAAGAAAAGGAGTACACTCTTTATAAGAATTATAAAATAATAATCCGTA
TAGAATCGGGGTGCATGGCG

Downstream 100 bases:

>100_bases
ATAAAGAAAGAGACTAACGATTACGTTAGTCTCTTTCTTTATTTATAAATATTTGTGTGCTTTATAGTTTTTTTATTATA
TTTCTCATCAAATTCTTTTC

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MVKEELKEALEMLKNTGVRITPQRHAILEYLVESMTHPTADEIYKALEGKFPNMSVATVYNNLRVFKEVGLVKELTYGDA
SSRFDYVTSQHYHVICEKCGKIVDFPYEGLEKLEDEAAKTTGFVINSHRLEIYGVCPECHKAQ

Sequences:

>Translated_143_residues
MVKEELKEALEMLKNTGVRITPQRHAILEYLVESMTHPTADEIYKALEGKFPNMSVATVYNNLRVFKEVGLVKELTYGDA
SSRFDYVTSQHYHVICEKCGKIVDFPYEGLEKLEDEAAKTTGFVINSHRLEIYGVCPECHKAQ
>Mature_143_residues
MVKEELKEALEMLKNTGVRITPQRHAILEYLVESMTHPTADEIYKALEGKFPNMSVATVYNNLRVFKEVGLVKELTYGDA
SSRFDYVTSQHYHVICEKCGKIVDFPYEGLEKLEDEAAKTTGFVINSHRLEIYGVCPECHKAQ

Specific function: Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=128, Percent_Identity=33.59375, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16317; Mature: 16317

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKEELKEALEMLKNTGVRITPQRHAILEYLVESMTHPTADEIYKALEGKFPNMSVATVY
CCHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHH
NNLRVFKEVGLVKELTYGDASSRFDYVTSQHYHVICEKCGKIVDFPYEGLEKLEDEAAKT
HHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
TGFVINSHRLEIYGVCPECHKAQ
HCEEEECCEEEEEEECCHHCCCC
>Mature Secondary Structure
MVKEELKEALEMLKNTGVRITPQRHAILEYLVESMTHPTADEIYKALEGKFPNMSVATVY
CCHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHH
NNLRVFKEVGLVKELTYGDASSRFDYVTSQHYHVICEKCGKIVDFPYEGLEKLEDEAAKT
HHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
TGFVINSHRLEIYGVCPECHKAQ
HCEEEECCEEEEEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202460; 9384377; 9701813; 12100544 [H]