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The map label for this gene is qacR [H]

Identifier: 152974212

GI number: 152974212

Start: 433637

End: 434221

Strand: Direct

Name: qacR [H]

Synonym: Bcer98_0376

Alternate gene names: 152974212

Gene position: 433637-434221 (Clockwise)

Preceding gene: 152974211

Following gene: 152974213

Centisome position: 10.61

GC content: 33.33

Gene sequence:

>585_bases
ATGCGAAAAAGTGCAGAAGAAATAAAAAAAGAAATTGCATACAAAGCAGAAGAATTATTTTCGCAAAAAGGTTACGCTGC
AACATCTATGGAAGAAATTTGCGAAATTACAGAGCGCAGTAAAGGAAGCATTTATTATCATTTCAAAAGTAAAGAAGAAC
TATTTTTATTTGTGGTCAAACAACATACGTATGATTGGATTGAGAAGTGGAATGTGAAAGAAAAGCAATATCATACGAGT
ACTGAAAAACTATATGGTCTTGCGGAATTTCATGTAGAAGATACACAACACCCGATTTTTAGTGCGGTAGAAGAGTTTTC
TACAAGCCAAGTGGTGAGTAAAGAAGTACTAGATGAAATGCTTACTTTAGCAAGAGCATCATATGGTGTATTTGAAAAAT
TAATTGAGGAAGGAATCCAATCTGGGGAATTTCGTCAGGATAATATTCGTGATCTTATGTATATTGTAAATGGTTTATTG
TCTGGGCTTGGTGTGCTTTATTATGAACTTGATCCTATAGAGATGAAACGAGTTTATAAAAAAGCAATTGATGTATTGTT
ACAAGGAATGGCAGCTGATTCTTAA

Upstream 100 bases:

>100_bases
TTTAAAAAATATTTTTTCTGAATTTAGGAAATATCACCTTGTAATGAAGATTTTATATTTGTTATCATTAGACTGAACGG
TCGGTTTTTTGGAGGGGAAT

Downstream 100 bases:

>100_bases
ATCAGTAGTCTTTCTCTTATAAAAATAGACCGAACGGTCGGTTTATAAGGAGGTTCAAATGAAAAATTTATTTAGTAATC
GCGCTTTTTTATTAGTCACG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MRKSAEEIKKEIAYKAEELFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQHTYDWIEKWNVKEKQYHTS
TEKLYGLAEFHVEDTQHPIFSAVEEFSTSQVVSKEVLDEMLTLARASYGVFEKLIEEGIQSGEFRQDNIRDLMYIVNGLL
SGLGVLYYELDPIEMKRVYKKAIDVLLQGMAADS

Sequences:

>Translated_194_residues
MRKSAEEIKKEIAYKAEELFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQHTYDWIEKWNVKEKQYHTS
TEKLYGLAEFHVEDTQHPIFSAVEEFSTSQVVSKEVLDEMLTLARASYGVFEKLIEEGIQSGEFRQDNIRDLMYIVNGLL
SGLGVLYYELDPIEMKRVYKKAIDVLLQGMAADS
>Mature_194_residues
MRKSAEEIKKEIAYKAEELFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQHTYDWIEKWNVKEKQYHTS
TEKLYGLAEFHVEDTQHPIFSAVEEFSTSQVVSKEVLDEMLTLARASYGVFEKLIEEGIQSGEFRQDNIRDLMYIVNGLL
SGLGVLYYELDPIEMKRVYKKAIDVLLQGMAADS

Specific function: Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR013571
- InterPro:   IPR001647 [H]

Pfam domain/function: PF08360 TetR_C_5; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22555; Mature: 22555

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSAEEIKKEIAYKAEELFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVK
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEHHHHH
QHTYDWIEKWNVKEKQYHTSTEKLYGLAEFHVEDTQHPIFSAVEEFSTSQVVSKEVLDEM
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LTLARASYGVFEKLIEEGIQSGEFRQDNIRDLMYIVNGLLSGLGVLYYELDPIEMKRVYK
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KAIDVLLQGMAADS
HHHHHHHHHHHCCC
>Mature Secondary Structure
MRKSAEEIKKEIAYKAEELFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVK
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEHHHHH
QHTYDWIEKWNVKEKQYHTSTEKLYGLAEFHVEDTQHPIFSAVEEFSTSQVVSKEVLDEM
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LTLARASYGVFEKLIEEGIQSGEFRQDNIRDLMYIVNGLLSGLGVLYYELDPIEMKRVYK
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KAIDVLLQGMAADS
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]