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The map label for this gene is arcB [H]

Identifier: 152974185

GI number: 152974185

Start: 397493

End: 398491

Strand: Direct

Name: arcB [H]

Synonym: Bcer98_0349

Alternate gene names: 152974185

Gene position: 397493-398491 (Clockwise)

Preceding gene: 152974184

Following gene: 152974186

Centisome position: 9.73

GC content: 36.54

Gene sequence:

>999_bases
ATGTTAATGACGAGATCAAACTTAAAAGGAAGAAGTTTTCTTGCTGAAAAAGATTTTACAAAAGAAGAATTATTATATTT
TCTTGATTTAGCAGCGGAATTAAAAGAGAAAAAGAAAAATGGTATCCCACATCATTATTTAGAAGGAAAAAACGTTGCAC
TCCTATTTGAAAAAACTTCAACCCGTACAAGATGCGCATTTACAGTCGCTTGTACTGATTTGGGTGCAAATCCTGAATAT
TTGGGAAAAGGTGATATTCAGCTTGGTAAAAAGGAATCTGTTGAAGATACAGCAAAAGTGTTAGGCCGTATGTTTGATGG
AATTGAGTTCCGTGGTTTTTCTCATGAAACAGTAGAATCGTTAGCTGCAAACTCTGGTGTGCCAGTATGGAACGGTTTAA
CAGATATGTGGCATCCGACACAAACACTTGCAGACCTTCTAACAATTAAAGAGCACGTAGGGCATTTGAAAGGTGTGAAG
CTTGTTTATGTTGGTGATGGCCGGAATAATGTAGCGAATAGTTTATTAGTTGGTGGTTCAATTGTTGGAATGGAAGTTCG
TATTTGTGCACCAGAGTCATTATGGCCAGCGCAAGAAGTAATCGACTTAGCGAAACAATATAGTAATCGTGTTATGGTAA
CAAGCGATGTGGAAGAAGCGGTTGCAGATGCAGATGTCATTTATACAGATGTATGGGTATCTATGGGAGAAGAAGATAAA
TTTGCTGAACGGATTGCTTTATTAACGCCTTATCAAGTGAATATGCAAATGATTCAAGCAACAGGAAATGATAATGTGAT
TTTCCTACATTGTTTACCTGCATTTCATGATGTGGAAACAATGTATGGTAAAGAAATTTATGAAAAATACGGCTTGAACG
AAATGGAGGTAACAGACGAGGTATTCCGCAGTAAATATTCAAAAGTATTTGATCAAGCTGAAAATAGAATGCACACAATT
AAAGCGGTTATGGCAGCTACTTTAGGGGATATGAAATAA

Upstream 100 bases:

>100_bases
TCGGAATTATCACGCGGTCGTGGGGGTCCACGTTGCATGAGTATGCCGATTGTTAGAAAAGATATTTAGTGATAAATAAC
GGAGAAAGTAGGGATGAACG

Downstream 100 bases:

>100_bases
AGAAGGAAGTATTGCTTCCTTCCTTTCTCCTCCTTTGGATATAATCATTCACTATTTGTAATATTGCAAATTAAGAGAGG
TGAGTGGAATGGATGAAGAA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLMTRSNLKGRSFLAEKDFTKEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTSTRTRCAFTVACTDLGANPEY
LGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFSHETVESLAANSGVPVWNGLTDMWHPTQTLADLLTIKEHVGHLKGVK
LVYVGDGRNNVANSLLVGGSIVGMEVRICAPESLWPAQEVIDLAKQYSNRVMVTSDVEEAVADADVIYTDVWVSMGEEDK
FAERIALLTPYQVNMQMIQATGNDNVIFLHCLPAFHDVETMYGKEIYEKYGLNEMEVTDEVFRSKYSKVFDQAENRMHTI
KAVMAATLGDMK

Sequences:

>Translated_332_residues
MLMTRSNLKGRSFLAEKDFTKEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTSTRTRCAFTVACTDLGANPEY
LGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFSHETVESLAANSGVPVWNGLTDMWHPTQTLADLLTIKEHVGHLKGVK
LVYVGDGRNNVANSLLVGGSIVGMEVRICAPESLWPAQEVIDLAKQYSNRVMVTSDVEEAVADADVIYTDVWVSMGEEDK
FAERIALLTPYQVNMQMIQATGNDNVIFLHCLPAFHDVETMYGKEIYEKYGLNEMEVTDEVFRSKYSKVFDQAENRMHTI
KAVMAATLGDMK
>Mature_332_residues
MLMTRSNLKGRSFLAEKDFTKEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTSTRTRCAFTVACTDLGANPEY
LGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFSHETVESLAANSGVPVWNGLTDMWHPTQTLADLLTIKEHVGHLKGVK
LVYVGDGRNNVANSLLVGGSIVGMEVRICAPESLWPAQEVIDLAKQYSNRVMVTSDVEEAVADADVIYTDVWVSMGEEDK
FAERIALLTPYQVNMQMIQATGNDNVIFLHCLPAFHDVETMYGKEIYEKYGLNEMEVTDEVFRSKYSKVFDQAENRMHTI
KAVMAATLGDMK

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=334, Percent_Identity=38.622754491018, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI18105007, Length=331, Percent_Identity=26.5861027190332, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1786469, Length=333, Percent_Identity=54.6546546546547, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1790703, Length=331, Percent_Identity=55.5891238670695, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI48994908, Length=371, Percent_Identity=26.6846361185984, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI2367364, Length=330, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193204318, Length=269, Percent_Identity=27.8810408921933, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322373, Length=335, Percent_Identity=32.8358208955224, Blast_Score=169, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6322331, Length=286, Percent_Identity=25.8741258741259, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24642586, Length=330, Percent_Identity=27.8787878787879, Blast_Score=95, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37178; Mature: 37178

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMTRSNLKGRSFLAEKDFTKEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTS
CCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCC
TRTRCAFTVACTDLGANPEYLGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFSHETVES
CCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEECCCCHHHHHH
LAANSGVPVWNGLTDMWHPTQTLADLLTIKEHVGHLKGVKLVYVGDGRNNVANSLLVGGS
HHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCHHCCEEEEEEECCCCHHHHHHEECCE
IVGMEVRICAPESLWPAQEVIDLAKQYSNRVMVTSDVEEAVADADVIYTDVWVSMGEEDK
EEEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEECCHHHHHHCCHHEEEEHHHHCCCCHH
FAERIALLTPYQVNMQMIQATGNDNVIFLHCLPAFHDVETMYGKEIYEKYGLNEMEVTDE
HHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHH
VFRSKYSKVFDQAENRMHTIKAVMAATLGDMK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLMTRSNLKGRSFLAEKDFTKEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTS
CCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCC
TRTRCAFTVACTDLGANPEYLGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFSHETVES
CCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEECCCCHHHHHH
LAANSGVPVWNGLTDMWHPTQTLADLLTIKEHVGHLKGVKLVYVGDGRNNVANSLLVGGS
HHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCHHCCEEEEEEECCCCHHHHHHEECCE
IVGMEVRICAPESLWPAQEVIDLAKQYSNRVMVTSDVEEAVADADVIYTDVWVSMGEEDK
EEEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEECCHHHHHHCCHHEEEEHHHHCCCCHH
FAERIALLTPYQVNMQMIQATGNDNVIFLHCLPAFHDVETMYGKEIYEKYGLNEMEVTDE
HHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHH
VFRSKYSKVFDQAENRMHTIKAVMAATLGDMK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA