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The map label for this gene is atoC [C]

Identifier: 152974145

GI number: 152974145

Start: 348658

End: 350037

Strand: Direct

Name: atoC [C]

Synonym: Bcer98_0304

Alternate gene names: 152974145

Gene position: 348658-350037 (Clockwise)

Preceding gene: 152974144

Following gene: 152974146

Centisome position: 8.53

GC content: 35.87

Gene sequence:

>1380_bases
ATGGTTGCAGAAAAGGAAAGAGCATATATGGATTTAAAAGATGTATTTGAATATGCGTTTGACGAAATCTTTGTTACGGA
TGAGAAAGGGATTGTTGTACGTGTAAATAGTACATGTGAAAGGCACTATCAATTGTCCGCGAAAGAATTGATTGGGAAAC
ATGTGAAAGATTTGCAAAAGGAAGGGATTTTCTATCCATCTGCAACATTAGAAGTCATTGAGAAGAAGAAACCAATTGAA
CTTGTTCAGACAACAAAATCAGGTGAGTATTTACATGTTCGTACAAGACCGGTGTTTGATGCAAAGGGAAATTTACGTAG
AGTCATCAGTTATTCTCGTGATCTCACTGAACTTTATCAATTACGAAAAAAAGTAGAGGAGATGGATCATCAATTAAAGA
CATATAAAAGGGAATTACGAGAAACATATGAGCACGAAGGACTTATTTTTAAAAGTGTAGCTATGCAGAAAATAGTCGAA
ACAATCAAAAAAATATCCATGGTAGATAGTACAGTCCTCATTTTGGGTGAGACCGGTGTAGGAAAGAGTAGATTAGTACG
TCATTTACATGAAATTAGCCATCGAAAAAATGAAGTGTTTTATGAAATGAACTGTGCGGCATTGCCAACAAATCTTATTG
AATCAGAGCTATTTGGATATGCTGGAGGGTCTTTTACGGGCGCCAATCGTGAAGGGAAGAAAGGAATATTAGAACTCGCA
CATAAAGGAACGCTTTTTTTAGATGAAATAGGAGAAATACCGCTAGAAATGCAAGCGAAATTATTACAAGTGCTACAGGA
AAAAACATTCCGCCCGGTAGGGGGTAGAGAATTAAAAAAGGTGGATGTTCGTATTGTAGCAGCTACGAATAGAAATTTAG
CAGAAATGGTGAAACAAGGGACTTTTCGAAAAGACTTGTTTTACCGTCTAAATGTCATACCGATTCAAATTCCGCCCCTT
CGTGAAAGAACAGAGGATATTTTGCCATTAGTTTATCATTATTTACAGCACTTTAATGAAAAGTATGGACGAGATGTGAA
ATTAGCCCCTAGTACATTACAAATGTTTGTAGGATATCCTTGGGAAGGGAATAATCGTGAAATTGAGAATGTAATTGAGC
GGCTTGTTATTACTGCTGATGATATTGTTACGATAGAAGATTTACCAGTATCTATGCAAGAAGTAACGATTGAACAATCT
GGTCAAAGTCTCTACCAAATGTTGGAGGAAGTAGAGCGGAATATTATTTTAAAAGCATATAAAACATATGGATCAAGCTA
TAAAGTAGCAGAGTTTTTGAAAATAAGTCAATCGGCAGCTACTCGGAAAATTAAAAAGTTAATAGGAGGGGATTTCATAG
TTGGGAGAGAAGAAACTTAA

Upstream 100 bases:

>100_bases
TAAAAATACAGAAAATTCCCTTAAATTAAGTTTTAGATTTATAATAGAATATAAGAGGTAAATAATTGGAGTAAGGGATT
GACTTTGAGGAGTGGCTAGA

Downstream 100 bases:

>100_bases
AAAGGTGTTATCACGTTTTGATGTTCTTTTCCTTGCGATCGGTGCAATGCTTGGATGGGGCTGGGTTGTTCTCTCGGGGG
ATTGGGTTACATCTGCTGGT

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: ORF1 [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MVAEKERAYMDLKDVFEYAFDEIFVTDEKGIVVRVNSTCERHYQLSAKELIGKHVKDLQKEGIFYPSATLEVIEKKKPIE
LVQTTKSGEYLHVRTRPVFDAKGNLRRVISYSRDLTELYQLRKKVEEMDHQLKTYKRELRETYEHEGLIFKSVAMQKIVE
TIKKISMVDSTVLILGETGVGKSRLVRHLHEISHRKNEVFYEMNCAALPTNLIESELFGYAGGSFTGANREGKKGILELA
HKGTLFLDEIGEIPLEMQAKLLQVLQEKTFRPVGGRELKKVDVRIVAATNRNLAEMVKQGTFRKDLFYRLNVIPIQIPPL
RERTEDILPLVYHYLQHFNEKYGRDVKLAPSTLQMFVGYPWEGNNREIENVIERLVITADDIVTIEDLPVSMQEVTIEQS
GQSLYQMLEEVERNIILKAYKTYGSSYKVAEFLKISQSAATRKIKKLIGGDFIVGREET

Sequences:

>Translated_459_residues
MVAEKERAYMDLKDVFEYAFDEIFVTDEKGIVVRVNSTCERHYQLSAKELIGKHVKDLQKEGIFYPSATLEVIEKKKPIE
LVQTTKSGEYLHVRTRPVFDAKGNLRRVISYSRDLTELYQLRKKVEEMDHQLKTYKRELRETYEHEGLIFKSVAMQKIVE
TIKKISMVDSTVLILGETGVGKSRLVRHLHEISHRKNEVFYEMNCAALPTNLIESELFGYAGGSFTGANREGKKGILELA
HKGTLFLDEIGEIPLEMQAKLLQVLQEKTFRPVGGRELKKVDVRIVAATNRNLAEMVKQGTFRKDLFYRLNVIPIQIPPL
RERTEDILPLVYHYLQHFNEKYGRDVKLAPSTLQMFVGYPWEGNNREIENVIERLVITADDIVTIEDLPVSMQEVTIEQS
GQSLYQMLEEVERNIILKAYKTYGSSYKVAEFLKISQSAATRKIKKLIGGDFIVGREET
>Mature_459_residues
MVAEKERAYMDLKDVFEYAFDEIFVTDEKGIVVRVNSTCERHYQLSAKELIGKHVKDLQKEGIFYPSATLEVIEKKKPIE
LVQTTKSGEYLHVRTRPVFDAKGNLRRVISYSRDLTELYQLRKKVEEMDHQLKTYKRELRETYEHEGLIFKSVAMQKIVE
TIKKISMVDSTVLILGETGVGKSRLVRHLHEISHRKNEVFYEMNCAALPTNLIESELFGYAGGSFTGANREGKKGILELA
HKGTLFLDEIGEIPLEMQAKLLQVLQEKTFRPVGGRELKKVDVRIVAATNRNLAEMVKQGTFRKDLFYRLNVIPIQIPPL
RERTEDILPLVYHYLQHFNEKYGRDVKLAPSTLQMFVGYPWEGNNREIENVIERLVITADDIVTIEDLPVSMQEVTIEQS
GQSLYQMLEEVERNIILKAYKTYGSSYKVAEFLKISQSAATRKIKKLIGGDFIVGREET

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=347, Percent_Identity=41.2103746397695, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1789233, Length=320, Percent_Identity=39.6875, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI87082117, Length=261, Percent_Identity=44.0613026819923, Blast_Score=231, Evalue=8e-62,
Organism=Escherichia coli, GI1789087, Length=275, Percent_Identity=44.7272727272727, Blast_Score=228, Evalue=9e-61,
Organism=Escherichia coli, GI1790437, Length=308, Percent_Identity=40.2597402597403, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI1790299, Length=328, Percent_Identity=40.5487804878049, Blast_Score=214, Evalue=7e-57,
Organism=Escherichia coli, GI1787583, Length=303, Percent_Identity=36.963696369637, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1786524, Length=365, Percent_Identity=34.7945205479452, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI1788905, Length=243, Percent_Identity=41.5637860082305, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI87082152, Length=325, Percent_Identity=37.2307692307692, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI87081872, Length=237, Percent_Identity=40.084388185654, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI87081858, Length=462, Percent_Identity=26.6233766233766, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789828, Length=243, Percent_Identity=34.5679012345679, Blast_Score=151, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR002078 [H]

Pfam domain/function: PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 52917; Mature: 52917

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAEKERAYMDLKDVFEYAFDEIFVTDEKGIVVRVNSTCERHYQLSAKELIGKHVKDLQK
CCCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCHHHHHHCCCHHHHHHHHHHHHHH
EGIFYPSATLEVIEKKKPIELVQTTKSGEYLHVRTRPVFDAKGNLRRVISYSRDLTELYQ
CCCCCCCHHHHHHHCCCCHHHHEECCCCCEEEEECCCCCCCCCCHHHHHHHHCCHHHHHH
LRKKVEEMDHQLKTYKRELRETYEHEGLIFKSVAMQKIVETIKKISMVDSTVLILGETGV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
GKSRLVRHLHEISHRKNEVFYEMNCAALPTNLIESELFGYAGGSFTGANREGKKGILELA
CHHHHHHHHHHHHCCCCCEEEEECCHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
HKGTLFLDEIGEIPLEMQAKLLQVLQEKTFRPVGGRELKKVDVRIVAATNRNLAEMVKQG
HCCCEEHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCHHHHHHCC
TFRKDLFYRLNVIPIQIPPLRERTEDILPLVYHYLQHFNEKYGRDVKLAPSTLQMFVGYP
CHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHEECC
WEGNNREIENVIERLVITADDIVTIEDLPVSMQEVTIEQSGQSLYQMLEEVERNIILKAY
CCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
KTYGSSYKVAEFLKISQSAATRKIKKLIGGDFIVGREET
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
>Mature Secondary Structure
MVAEKERAYMDLKDVFEYAFDEIFVTDEKGIVVRVNSTCERHYQLSAKELIGKHVKDLQK
CCCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCHHHHHHCCCHHHHHHHHHHHHHH
EGIFYPSATLEVIEKKKPIELVQTTKSGEYLHVRTRPVFDAKGNLRRVISYSRDLTELYQ
CCCCCCCHHHHHHHCCCCHHHHEECCCCCEEEEECCCCCCCCCCHHHHHHHHCCHHHHHH
LRKKVEEMDHQLKTYKRELRETYEHEGLIFKSVAMQKIVETIKKISMVDSTVLILGETGV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
GKSRLVRHLHEISHRKNEVFYEMNCAALPTNLIESELFGYAGGSFTGANREGKKGILELA
CHHHHHHHHHHHHCCCCCEEEEECCHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
HKGTLFLDEIGEIPLEMQAKLLQVLQEKTFRPVGGRELKKVDVRIVAATNRNLAEMVKQG
HCCCEEHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCHHHHHHCC
TFRKDLFYRLNVIPIQIPPLRERTEDILPLVYHYLQHFNEKYGRDVKLAPSTLQMFVGYP
CHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHEECC
WEGNNREIENVIERLVITADDIVTIEDLPVSMQEVTIEQSGQSLYQMLEEVERNIILKAY
CCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
KTYGSSYKVAEFLKISQSAATRKIKKLIGGDFIVGREET
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]