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The map label for this gene is acpS

Identifier: 152974080

GI number: 152974080

Start: 248342

End: 248701

Strand: Direct

Name: acpS

Synonym: Bcer98_0236

Alternate gene names: 152974080

Gene position: 248342-248701 (Clockwise)

Preceding gene: 152974078

Following gene: 152974081

Centisome position: 6.08

GC content: 35.0

Gene sequence:

>360_bases
ATGATTCTAGGTATTGGGATAGACATTATTGAGTTAAATCGAATTGAAAAGATGATAAATGGAAAACTGAACTTTATAGA
AAGGATTTTGACTGAAACAGAACGCGACGTTGCTGCTAAGTTAAAGGGGAAGCGTCTTGTAGAATTTGTAGCTGGAAGAT
TTGCAGCAAAAGAGGCGTATTCTAAAGCTGTTGGAACGGGTATTGGAAAAGAAGTGAGTTTTTTAGATATTGAAATAAAA
AATGATCAAAAAGGGAAACCAGTACTTTTTACAAATACGGAATATATTGTCCATCTATCCATTAGTCATAGTAGAGAATT
CGCAGTTGCTCAAGTTGTTTTAGAAAGCCCGTCATGCTAG

Upstream 100 bases:

>100_bases
TCCTTGGCATTTTATAATCCCACCTTTTGCATCGGAAAGATTCTCTGTTATTCTTACAATATGAATGAAGAGAGAGAAAT
AGAAGAAGGGGATTGTTAGA

Downstream 100 bases:

>100_bases
TCTGCATATTTTGAAGCTTTGTCTCATATATTTGAGGTAGCGATAGGGAAGAAATATCTTCCATTTATTTATGGGGCAAA
GGGGCTGAAATGATGAAAAG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MILGIGIDIIELNRIEKMINGKLNFIERILTETERDVAAKLKGKRLVEFVAGRFAAKEAYSKAVGTGIGKEVSFLDIEIK
NDQKGKPVLFTNTEYIVHLSISHSREFAVAQVVLESPSC

Sequences:

>Translated_119_residues
MILGIGIDIIELNRIEKMINGKLNFIERILTETERDVAAKLKGKRLVEFVAGRFAAKEAYSKAVGTGIGKEVSFLDIEIK
NDQKGKPVLFTNTEYIVHLSISHSREFAVAQVVLESPSC
>Mature_119_residues
MILGIGIDIIELNRIEKMINGKLNFIERILTETERDVAAKLKGKRLVEFVAGRFAAKEAYSKAVGTGIGKEVSFLDIEIK
NDQKGKPVLFTNTEYIVHLSISHSREFAVAQVVLESPSC

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=126, Percent_Identity=35.7142857142857, Blast_Score=69, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_BACCN (A7GKE4)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001373597.1
- ProteinModelPortal:   A7GKE4
- SMR:   A7GKE4
- STRING:   A7GKE4
- EnsemblBacteria:   EBBACT00000036653
- GeneID:   5344619
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_0236
- eggNOG:   COG0736
- GeneTree:   EBGT00050000001692
- HOGENOM:   HBG734479
- OMA:   VHVSITH
- ProtClustDB:   PRK00070
- BioCyc:   BCER315749:BCER98_0236-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13221; Mature: 13221

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILGIGIDIIELNRIEKMINGKLNFIERILTETERDVAAKLKGKRLVEFVAGRFAAKEAY
CEEECCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
SKAVGTGIGKEVSFLDIEIKNDQKGKPVLFTNTEYIVHLSISHSREFAVAQVVLESPSC
HHHHCCCCCCCEEEEEEEECCCCCCCCEEEECCEEEEEEEECCCCHHHHHHHEECCCCC
>Mature Secondary Structure
MILGIGIDIIELNRIEKMINGKLNFIERILTETERDVAAKLKGKRLVEFVAGRFAAKEAY
CEEECCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
SKAVGTGIGKEVSFLDIEIKNDQKGKPVLFTNTEYIVHLSISHSREFAVAQVVLESPSC
HHHHCCCCCCCEEEEEEEECCCCCCCCEEEECCEEEEEEEECCCCHHHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA