| Definition | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 chromosome, complete genome. |
|---|---|
| Accession | NC_009648 |
| Length | 5,315,120 |
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The map label for this gene is lacE [H]
Identifier: 152971596
GI number: 152971596
Start: 3372027
End: 3373004
Strand: Direct
Name: lacE [H]
Synonym: KPN_03074
Alternate gene names: 152971596
Gene position: 3372027-3373004 (Clockwise)
Preceding gene: 152971595
Following gene: 152971597
Centisome position: 63.44
GC content: 60.94
Gene sequence:
>978_bases ATGTTGTCGCTGATGTCGTTTCTGCTGGTAGCCGCGCCGCTGAAAGATGGCCAGATCTCTACTGCCTACTTCTCCGGTCA GGGGATCTTTACCGCCATTCTGGTGGCCATCTATTCCACCGAGCTGTACGCCTTCCTCAAACGGCATAACATCACCATTC GCCTGCCGCCGGAAGTGCCTGCCGGGGTGGCGCGCTCGTTTGAAATCCTGATCCCGGTGCTGGCGATCATTCTGACGCTG CATCCGCTGAACCTGTTTATCGAAGCCCAGCTGGGGATGATCATTCCGGAAGCGATCATGTCGCTGGTGAAGCCGCTGGT CGCGGCTTCCGATACGCTGCCGGCGATCCTCCTGTCGGTGCTGGTCTGTCAGGTGCTGTGGTTCGCCGGGATCCACGGCG CGCTGATCGTCACCGGGATCATGAACCCGTTCTGGATGGCCAACCTGTCGGTCAATCAGGCGGCCATGGCCGCTGGCACC GCTATCCCGCACATCTATGTCCAGGGCTTCTGGGATCACTATCTGCTGATCGGCGGCGTCGGCTCCACCCTGCCGCTGGC GCTGATGCTGCTGCGCAGCAAGGCCGTGCATCTGCGGACGATCGGCCGGATGGGGGTCGTGCCGGGCGTATTTAACATCA ACGAACCGATTCTGTTCGGCGCGCCGATCATCATGAACCCGCTGTTTTTCCTGCCGTTCGTGCTGGTGCCGATGGTCAAC GCGACCCTGGCGTACTTCGCGCTGAAGCTGGACCTGGTCAGCCGCGTAGTGTCGATGACGCCGTGGACAACGCCGGCGCC TATCGGCGCCTCGTGGGCGGCGAACTGGAGCTTTAGCCCGGTGATCCTGTGCCTCATTTGTATGGCTACCGCCATGGTGA TGTACCTGCCATTTCTCAAAGCTTACGAAAAACAGCTGCTGGCCCAGGAGCGTGAAAACGCCGTCGGCCAGGCTGACAAC GCGGCGCAAACCGCTTAA
Upstream 100 bases:
>100_bases CCGTTCAACTTCAGCATGGGGGTGATGACCCTGTTTATCGCCGTCGGGGATCGCCGCCAGCCTCGCCAAACACCATCATC TGGACTCGCTGACCGCCGGG
Downstream 100 bases:
>100_bases CGCTAACGATTCAGAGGATAATCATGGAATTAGAAGAACAGGTGATGGGGATCATCATCAATGCCGGCCAGTCACGTAGC CTGTGCTACGAAGCGCTGCA
Product: PEP-dependent phosphotransferase enzyme II
Products: NA
Alternate protein names: EIICB-Lac; EII-Lac; Lactose permease IIC component; PTS system lactose-specific EIIC component; Lactose-specific phosphotransferase enzyme IIB component; PTS system lactose-specific EIIB component [H]
Number of amino acids: Translated: 325; Mature: 325
Protein sequence:
>325_residues MLSLMSFLLVAAPLKDGQISTAYFSGQGIFTAILVAIYSTELYAFLKRHNITIRLPPEVPAGVARSFEILIPVLAIILTL HPLNLFIEAQLGMIIPEAIMSLVKPLVAASDTLPAILLSVLVCQVLWFAGIHGALIVTGIMNPFWMANLSVNQAAMAAGT AIPHIYVQGFWDHYLLIGGVGSTLPLALMLLRSKAVHLRTIGRMGVVPGVFNINEPILFGAPIIMNPLFFLPFVLVPMVN ATLAYFALKLDLVSRVVSMTPWTTPAPIGASWAANWSFSPVILCLICMATAMVMYLPFLKAYEKQLLAQERENAVGQADN AAQTA
Sequences:
>Translated_325_residues MLSLMSFLLVAAPLKDGQISTAYFSGQGIFTAILVAIYSTELYAFLKRHNITIRLPPEVPAGVARSFEILIPVLAIILTL HPLNLFIEAQLGMIIPEAIMSLVKPLVAASDTLPAILLSVLVCQVLWFAGIHGALIVTGIMNPFWMANLSVNQAAMAAGT AIPHIYVQGFWDHYLLIGGVGSTLPLALMLLRSKAVHLRTIGRMGVVPGVFNINEPILFGAPIIMNPLFFLPFVLVPMVN ATLAYFALKLDLVSRVVSMTPWTTPAPIGASWAANWSFSPVILCLICMATAMVMYLPFLKAYEKQLLAQERENAVGQADN AAQTA >Mature_325_residues MLSLMSFLLVAAPLKDGQISTAYFSGQGIFTAILVAIYSTELYAFLKRHNITIRLPPEVPAGVARSFEILIPVLAIILTL HPLNLFIEAQLGMIIPEAIMSLVKPLVAASDTLPAILLSVLVCQVLWFAGIHGALIVTGIMNPFWMANLSVNQAAMAAGT AIPHIYVQGFWDHYLLIGGVGSTLPLALMLLRSKAVHLRTIGRMGVVPGVFNINEPILFGAPIIMNPLFFLPFVLVPMVN ATLAYFALKLDLVSRVVSMTPWTTPAPIGASWAANWSFSPVILCLICMATAMVMYLPFLKAYEKQLLAQERENAVGQADN AAQTA
Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This
COG id: COG1455
COG function: function code G; Phosphotransferase system cellobiose-specific component IIC
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIC type-3 domain [H]
Homologues:
Organism=Escherichia coli, GI1788032, Length=337, Percent_Identity=32.9376854599407, Blast_Score=162, Evalue=3e-41,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014350 - InterPro: IPR003501 - InterPro: IPR013012 - InterPro: IPR003352 - InterPro: IPR004501 - InterPro: IPR004801 [H]
Pfam domain/function: PF02378 PTS_EIIC; PF02302 PTS_IIB [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 35185; Mature: 35185
Theoretical pI: Translated: 8.08; Mature: 8.08
Prosite motif: PS51105 PTS_EIIC_TYPE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 4.6 %Met (Translated Protein) 5.5 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 4.6 %Met (Mature Protein) 5.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLSLMSFLLVAAPLKDGQISTAYFSGQGIFTAILVAIYSTELYAFLKRHNITIRLPPEVP CHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC AGVARSFEILIPVLAIILTLHPLNLFIEAQLGMIIPEAIMSLVKPLVAASDTLPAILLSV HHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH LVCQVLWFAGIHGALIVTGIMNPFWMANLSVNQAAMAAGTAIPHIYVQGFWDHYLLIGGV HHHHHHHHHCCHHHHHHHHHCCCHHEECCCCCHHHHHHCCCCCHHHEEHHHHHEEEECCC GSTLPLALMLLRSKAVHLRTIGRMGVVPGVFNINEPILFGAPIIMNPLFFLPFVLVPMVN CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHH ATLAYFALKLDLVSRVVSMTPWTTPAPIGASWAANWSFSPVILCLICMATAMVMYLPFLK HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH AYEKQLLAQERENAVGQADNAAQTA HHHHHHHHHHHHHHCCCCCCCCCCC >Mature Secondary Structure MLSLMSFLLVAAPLKDGQISTAYFSGQGIFTAILVAIYSTELYAFLKRHNITIRLPPEVP CHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC AGVARSFEILIPVLAIILTLHPLNLFIEAQLGMIIPEAIMSLVKPLVAASDTLPAILLSV HHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH LVCQVLWFAGIHGALIVTGIMNPFWMANLSVNQAAMAAGTAIPHIYVQGFWDHYLLIGGV HHHHHHHHHCCHHHHHHHHHCCCHHEECCCCCHHHHHHCCCCCHHHEEHHHHHEEEECCC GSTLPLALMLLRSKAVHLRTIGRMGVVPGVFNINEPILFGAPIIMNPLFFLPFVLVPMVN CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHH ATLAYFALKLDLVSRVVSMTPWTTPAPIGASWAANWSFSPVILCLICMATAMVMYLPFLK HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH AYEKQLLAQERENAVGQADNAAQTA HHHHHHHHHHHHHHCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 2125052 [H]