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The map label for this gene is proX [H]

Identifier: 152971537

GI number: 152971537

Start: 3309192

End: 3310175

Strand: Direct

Name: proX [H]

Synonym: KPN_03010

Alternate gene names: 152971537

Gene position: 3309192-3310175 (Clockwise)

Preceding gene: 152971536

Following gene: 152971538

Centisome position: 62.26

GC content: 57.83

Gene sequence:

>984_bases
ATGTTGGCCACCGCCGCCTTTGCCACCCTGCTCGCCACCAGCGCCTTCGCCGCCGACCTGCCGGGTAAAGGGATTACGGT
GAAGCCCGCTCAGAGCACTATCTCCGAAGAGAGCTTCCAGACCCTGCTGGTCAGTCGCGCGCTGGAGAAGCTGGGCTACA
CCGTCGAGAAACCCAGCGAAGTGGACTATAACGTTGCCTATACGTCGATTGCCGCCGGAGATACCACCTTTATCGCCACC
AACTGGCAACCGCTGCACGATGACATGTACGCCGCGGCTGGCGGTGATAACAAATTCTATCGCAAAGGAGTGTACGTCTC
AGGCGCCGCCCAGGGCTATTTGATCGACAAAAAAACCGCTGAGCAGTACCACATCACCTCCATCGATCAGCTCAAAGATC
CGCAGATCGCCAAACTGTTTGATACCAACAATGACGGTAAAGCGGATCTCACCGGCTGTACCCCAGGATGGGGCTGCGAA
GCAGTGATTAACCATCAGATTGACGCCTATGGCCTGAGCAAAACCGTCACCCATAACCAGGGCAACTACGCGGCGATGAT
GGCCGACACCATTGCCCGGTATAAAGAGGGTAAACCGGTGCTCTACTACACCTGGACGCCGTACTGGGTTAGCGACGTGC
TGAAGCCTGGCAAGGACGTCGTCTGGCTGCAGGTGCCGTTCTCCTCCCTGCCGGGCGAGCAGCAAAACATCGACACCAAA
CTGGCCAACGGCGCCAACTATGGCTTCCCGGTGAACACCATGCACATCGTCGCTAACAAAGCCTGGGCGGAGAAAAATCC
GGCCGCCGCCACTCTGTTTAGCGTCATGAAGCTGCCGATCGCCGACATCAACGCCGAGAATGCAATGATGCATGAAGGCC
ATGCTTCCGAAGCCGACATTAACGGCCACGTTGATGGCTGGATCAAAGCCCACCAGCCGCTGTTCGACAGCTGGGTGAAA
ACCGCCCTCGCCGCGCAGCAGTAA

Upstream 100 bases:

>100_bases
TCGATAAGTCGATAACAGCGCCGCTCCCCGACACCAGCCGATGCCCGGGAGCGGCCCTTCCCGTTAAACAATAAGAGGAA
CCACCATGCGACATAGTACG

Downstream 100 bases:

>100_bases
ACCCGCTCACGGATAAGGCCCAGCGCCTTATCCGGCCCCCTTGCCCCCTTTCTCGTGGCCAGGTCATAGAAAAGCGATTC
CAGGAATTTCCATAGTGTTA

Product: glycine betaine transporter periplasmic subunit

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MLATAAFATLLATSAFAADLPGKGITVKPAQSTISEESFQTLLVSRALEKLGYTVEKPSEVDYNVAYTSIAAGDTTFIAT
NWQPLHDDMYAAAGGDNKFYRKGVYVSGAAQGYLIDKKTAEQYHITSIDQLKDPQIAKLFDTNNDGKADLTGCTPGWGCE
AVINHQIDAYGLSKTVTHNQGNYAAMMADTIARYKEGKPVLYYTWTPYWVSDVLKPGKDVVWLQVPFSSLPGEQQNIDTK
LANGANYGFPVNTMHIVANKAWAEKNPAAATLFSVMKLPIADINAENAMMHEGHASEADINGHVDGWIKAHQPLFDSWVK
TALAAQQ

Sequences:

>Translated_327_residues
MLATAAFATLLATSAFAADLPGKGITVKPAQSTISEESFQTLLVSRALEKLGYTVEKPSEVDYNVAYTSIAAGDTTFIAT
NWQPLHDDMYAAAGGDNKFYRKGVYVSGAAQGYLIDKKTAEQYHITSIDQLKDPQIAKLFDTNNDGKADLTGCTPGWGCE
AVINHQIDAYGLSKTVTHNQGNYAAMMADTIARYKEGKPVLYYTWTPYWVSDVLKPGKDVVWLQVPFSSLPGEQQNIDTK
LANGANYGFPVNTMHIVANKAWAEKNPAAATLFSVMKLPIADINAENAMMHEGHASEADINGHVDGWIKAHQPLFDSWVK
TALAAQQ
>Mature_327_residues
MLATAAFATLLATSAFAADLPGKGITVKPAQSTISEESFQTLLVSRALEKLGYTVEKPSEVDYNVAYTSIAAGDTTFIAT
NWQPLHDDMYAAAGGDNKFYRKGVYVSGAAQGYLIDKKTAEQYHITSIDQLKDPQIAKLFDTNNDGKADLTGCTPGWGCE
AVINHQIDAYGLSKTVTHNQGNYAAMMADTIARYKEGKPVLYYTWTPYWVSDVLKPGKDVVWLQVPFSSLPGEQQNIDTK
LANGANYGFPVNTMHIVANKAWAEKNPAAATLFSVMKLPIADINAENAMMHEGHASEADINGHVDGWIKAHQPLFDSWVK
TALAAQQ

Specific function: Member of a multicomponent binding-protein-dependent transport system (the proU transporter) which serves as the glycine betaine/L-proline transporter [H]

COG id: COG2113

COG function: function code E; ABC-type proline/glycine betaine transport systems, periplasmic components

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789034, Length=327, Percent_Identity=79.2048929663608, Blast_Score=550, Evalue=1e-158,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007210 [H]

Pfam domain/function: PF04069 OpuAC [H]

EC number: NA

Molecular weight: Translated: 35560; Mature: 35560

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLATAAFATLLATSAFAADLPGKGITVKPAQSTISEESFQTLLVSRALEKLGYTVEKPSE
CCCHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VDYNVAYTSIAAGDTTFIATNWQPLHDDMYAAAGGDNKFYRKGVYVSGAAQGYLIDKKTA
CCCEEEEEEEECCCEEEEEECCCCCCCCCEEECCCCCCEEECCEEEECCCCEEEEECCCC
EQYHITSIDQLKDPQIAKLFDTNNDGKADLTGCTPGWGCEAVINHQIDAYGLSKTVTHNQ
CEEECCCHHHCCCCCEEEEEECCCCCCEEECCCCCCCCCHHHHCCCCCCCCCCEEEECCC
GNYAAMMADTIARYKEGKPVLYYTWTPYWVSDVLKPGKDVVWLQVPFSSLPGEQQNIDTK
CCEEHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCEEEEEECHHHCCCCCCCCCHH
LANGANYGFPVNTMHIVANKAWAEKNPAAATLFSVMKLPIADINAENAMMHEGHASEADI
HCCCCCCCCCCCEEEEEEEHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCC
NGHVDGWIKAHQPLFDSWVKTALAAQQ
CCCCCCEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLATAAFATLLATSAFAADLPGKGITVKPAQSTISEESFQTLLVSRALEKLGYTVEKPSE
CCCHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VDYNVAYTSIAAGDTTFIATNWQPLHDDMYAAAGGDNKFYRKGVYVSGAAQGYLIDKKTA
CCCEEEEEEEECCCEEEEEECCCCCCCCCEEECCCCCCEEECCEEEECCCCEEEEECCCC
EQYHITSIDQLKDPQIAKLFDTNNDGKADLTGCTPGWGCEAVINHQIDAYGLSKTVTHNQ
CEEECCCHHHCCCCCEEEEEECCCCCCEEECCCCCCCCCHHHHCCCCCCCCCCEEEECCC
GNYAAMMADTIARYKEGKPVLYYTWTPYWVSDVLKPGKDVVWLQVPFSSLPGEQQNIDTK
CCEEHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCEEEEEECHHHCCCCCCCCCHH
LANGANYGFPVNTMHIVANKAWAEKNPAAATLFSVMKLPIADINAENAMMHEGHASEADI
HCCCCCCCCCCCEEEEEEEHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCC
NGHVDGWIKAHQPLFDSWVKTALAAQQ
CCCCCCEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]