| Definition | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 chromosome, complete genome. |
|---|---|
| Accession | NC_009648 |
| Length | 5,315,120 |
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The map label for this gene is pcbC [H]
Identifier: 152971502
GI number: 152971502
Start: 3271054
End: 3272121
Strand: Direct
Name: pcbC [H]
Synonym: KPN_02975
Alternate gene names: 152971502
Gene position: 3271054-3272121 (Clockwise)
Preceding gene: 152971501
Following gene: 152971503
Centisome position: 61.54
GC content: 61.05
Gene sequence:
>1068_bases ATGACCGCCGTGAAGCACGCTTTTACTGAACTCCCGACCATCGATATCCGCGATCTGGCCGGCGATGACCTCGCCAGGCG TCAGGCGGTGGCCGACGCCATCGGCCGCGCGGCGCGCGAGGTGGGCTTTTTCTACATCACCGGCCACGGTATCGACCCGG CGCTGATCGCCGGCGTCCGCGAGGCGGCGAAGCAGATCTTCGCCCTGCCGATGGAGGAGAAGATGAACTATTACATCGGC CACTCCAAAAGCCATAAGGGCTACGTTCCGGAAGGAGAAGAGATCTACGGCTCCGGCAAGCCGGACCATAAAGAGGCTTT CGATATCGGCTTCCAGGCAGCGGATGACCATCCGCTGGTGCTCGCCGGTACGCCGCTGATCGGCGCCAACGAGTGGCCCG ATCTGCCAGATTTCCGCGCGCGGGTGCTGGCCTACTACGACGCGGTTTTCGCCCTCGGCCACCGTCTGTTCGACGCTTTC GCCCTCGCGCTCGGCCTGCCGGAAGGGTATTTCAAACCGATGGTGACCTGCCCGCCGGCTAAGCTGCGGCTGATCCATTA CCCGTTCGACGCCAGCGTCGAAGATGTTCCCGGAATTGGTGCACACACCGACTATGAGTGCTTCACCCTGCTGCTCGCCG ACCAGCCCGGCCTTGAAGTTCTCAATGAAGAAAGCGTGTGGATCGATGCACCTCCCGTCAAGAACGCCGCCGGAGAAGAG GCGTTCGTGATCAATATCGGCGACATGCTGGAAGTGCTCAGCGCTGGCACATTTGTTGCTACAGCCCACCGGGTGCGCAA AGTGCCGCAGGAGCGGTACTCCTTCCCGCTGTTTTTCGCCTGCGATTACCACACGCTGATCCGTCCGCTGCCGACTTTTC TCGCCGCCGGCGAAGCCGGTGAATATCAGGAGCTCAGCATCGGGGAGCATATGTGGAGCCAGGCCCTGCAAACCTATCGC TACCTGCGCGAAAAGGTCAATCGCGGTGAACTTCAGCTACCGGAGCGCGCGCGCGGCACCAATACGTTTGGCCATTTGAA AAAACAGGCTCAGCAAAAAAACCCCTAA
Upstream 100 bases:
>100_bases TTCCGGTGGCCGATCTCTGGTCGCTCAACGCCTGGATGGCCACGCGCCAGCAGGCCCACTTTCAGCAGTTTTTATCGCTC ACTGAACAGGAACCGCAGCC
Downstream 100 bases:
>100_bases CCACCCGTGAGGATCCATGATGACTAGCACCCTGAAAAAAATCTCGCGCCATGTCGCGCTTACCCTCGCCGTCAGCGCCT GTTTTTCCCCTGTCACCCAG
Product: putative oxidoreductase
Products: NA
Alternate protein names: IPNS [H]
Number of amino acids: Translated: 355; Mature: 354
Protein sequence:
>355_residues MTAVKHAFTELPTIDIRDLAGDDLARRQAVADAIGRAAREVGFFYITGHGIDPALIAGVREAAKQIFALPMEEKMNYYIG HSKSHKGYVPEGEEIYGSGKPDHKEAFDIGFQAADDHPLVLAGTPLIGANEWPDLPDFRARVLAYYDAVFALGHRLFDAF ALALGLPEGYFKPMVTCPPAKLRLIHYPFDASVEDVPGIGAHTDYECFTLLLADQPGLEVLNEESVWIDAPPVKNAAGEE AFVINIGDMLEVLSAGTFVATAHRVRKVPQERYSFPLFFACDYHTLIRPLPTFLAAGEAGEYQELSIGEHMWSQALQTYR YLREKVNRGELQLPERARGTNTFGHLKKQAQQKNP
Sequences:
>Translated_355_residues MTAVKHAFTELPTIDIRDLAGDDLARRQAVADAIGRAAREVGFFYITGHGIDPALIAGVREAAKQIFALPMEEKMNYYIG HSKSHKGYVPEGEEIYGSGKPDHKEAFDIGFQAADDHPLVLAGTPLIGANEWPDLPDFRARVLAYYDAVFALGHRLFDAF ALALGLPEGYFKPMVTCPPAKLRLIHYPFDASVEDVPGIGAHTDYECFTLLLADQPGLEVLNEESVWIDAPPVKNAAGEE AFVINIGDMLEVLSAGTFVATAHRVRKVPQERYSFPLFFACDYHTLIRPLPTFLAAGEAGEYQELSIGEHMWSQALQTYR YLREKVNRGELQLPERARGTNTFGHLKKQAQQKNP >Mature_354_residues TAVKHAFTELPTIDIRDLAGDDLARRQAVADAIGRAAREVGFFYITGHGIDPALIAGVREAAKQIFALPMEEKMNYYIGH SKSHKGYVPEGEEIYGSGKPDHKEAFDIGFQAADDHPLVLAGTPLIGANEWPDLPDFRARVLAYYDAVFALGHRLFDAFA LALGLPEGYFKPMVTCPPAKLRLIHYPFDASVEDVPGIGAHTDYECFTLLLADQPGLEVLNEESVWIDAPPVKNAAGEEA FVINIGDMLEVLSAGTFVATAHRVRKVPQERYSFPLFFACDYHTLIRPLPTFLAAGEAGEYQELSIGEHMWSQALQTYRY LREKVNRGELQLPERARGTNTFGHLKKQAQQKNP
Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]
COG id: COG3491
COG function: function code R; Isopenicillin N synthase and related dioxygenases
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Fe2OG dioxygenase domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002057 - InterPro: IPR002283 - InterPro: IPR005123 [H]
Pfam domain/function: PF03171 2OG-FeII_Oxy [H]
EC number: =1.21.3.1 [H]
Molecular weight: Translated: 39371; Mature: 39240
Theoretical pI: Translated: 5.40; Mature: 5.40
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTAVKHAFTELPTIDIRDLAGDDLARRQAVADAIGRAAREVGFFYITGHGIDPALIAGVR CCHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHH EAAKQIFALPMEEKMNYYIGHSKSHKGYVPEGEEIYGSGKPDHKEAFDIGFQAADDHPLV HHHHHHHCCCHHHHCCEEECCCCCCCCCCCCCHHCCCCCCCCCHHHHHCCCCCCCCCCEE LAGTPLIGANEWPDLPDFRARVLAYYDAVFALGHRLFDAFALALGLPEGYFKPMVTCPPA EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEECCCC KLRLIHYPFDASVEDVPGIGAHTDYECFTLLLADQPGLEVLNEESVWIDAPPVKNAAGEE CEEEEECCCCCCCCCCCCCCCCCCHHEEEEEEECCCCCHHCCCCCEEEECCCCCCCCCCC AFVINIGDMLEVLSAGTFVATAHRVRKVPQERYSFPLFFACDYHTLIRPLPTFLAAGEAG EEEEEHHHHHHHHHCCHHHHHHHHHHHCHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCC EYQELSIGEHMWSQALQTYRYLREKVNRGELQLPERARGTNTFGHLKKQAQQKNP CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHCCCC >Mature Secondary Structure TAVKHAFTELPTIDIRDLAGDDLARRQAVADAIGRAAREVGFFYITGHGIDPALIAGVR CHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHH EAAKQIFALPMEEKMNYYIGHSKSHKGYVPEGEEIYGSGKPDHKEAFDIGFQAADDHPLV HHHHHHHCCCHHHHCCEEECCCCCCCCCCCCCHHCCCCCCCCCHHHHHCCCCCCCCCCEE LAGTPLIGANEWPDLPDFRARVLAYYDAVFALGHRLFDAFALALGLPEGYFKPMVTCPPA EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEECCCC KLRLIHYPFDASVEDVPGIGAHTDYECFTLLLADQPGLEVLNEESVWIDAPPVKNAAGEE CEEEEECCCCCCCCCCCCCCCCCCHHEEEEEEECCCCCHHCCCCCEEEECCCCCCCCCCC AFVINIGDMLEVLSAGTFVATAHRVRKVPQERYSFPLFFACDYHTLIRPLPTFLAAGEAG EEEEEHHHHHHHHHCCHHHHHHHHHHHCHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCC EYQELSIGEHMWSQALQTYRYLREKVNRGELQLPERARGTNTFGHLKKQAQQKNP CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 1901702 [H]