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The map label for this gene is yycG [H]

Identifier: 152971061

GI number: 152971061

Start: 2757286

End: 2759220

Strand: Direct

Name: yycG [H]

Synonym: KPN_02522

Alternate gene names: 152971061

Gene position: 2757286-2759220 (Clockwise)

Preceding gene: 152971060

Following gene: 152971062

Centisome position: 51.88

GC content: 63.36

Gene sequence:

>1935_bases
GTGTCTGCGATCTTCGGGGCGGTCCGGCGTTGCCGGCCGCAGTTCCTGGCAGGCTGGCTGCTCAGCTGTGGATTATTCTT
GCTGCTGGTCGCCCCACAGGCGCAGGCGGCGACGCGCCAGGTGGGCATTGATATTCCGGTCCAGTGGTACGCGGACGCCA
GCGGCCAGATGACCCTCGATCGCTTCGCCGCCCTGCCCACAGACCAGCTCGCCACCACCCGGCAGATCCCCTCCTTTGGT
TATTCGCGAAAAACCTGGTGGCTGCGCAGCGAACTGCCGGGAACGTGGTTTGCCGGGGAGCCGCGCTGGCTGCAGCTGGG
CCCCTCTTTTGTCGACCATCTGACTATTTACTACCGGCCTCTGGGCAGCGATGCCCCCTGGGCACAGCGCACCTTTGGCG
ACCGCGACGGCGCCCGCGAGAGCGACCTGCACTACCGCGAAAGCGTGCTGATCCTCCCCCCGCCGCCGACCGCCGCCGGC
TATGAGGTGGTCTTTCGCCTGCAGAGCACCAGCACCCTGATCCTGCTGGCCTCGCTCTCCTCTGCGCAGGCGTTTGTGCA
GCGGGCCACCGCTGACACCGCTTTCTGGAGCTTCTACTTCGGCCTGGCCGCTGTCGCCAGCGGTGTGGCGCTTTGGCTGG
CGCTGGCCCTGCGCCGGCGTCTGCTATGGGGCATCTGTCTTTTCTCGCTCAATTATCCGCTGGTGGCCGCTCTGCACGGC
TTCCCGGAGTGGTTCTTCGGCCACGCCGCGCTGCCCTTCCAGGATTTTATGATCAGTAGCCTCTCGCTGTTCAGCTATGC
CACCGCCCTCTGGCTGCATAGCGAGATTTTTGATCTGAAGAAGAATATGCCGCGACTTCATCAGCTGCTGATCGCCGCCG
TGATACTCAACCTGGTACTGCAGGTCAGTATTCCGCTCGGGTTTTACGGCTTCGCGATGCAGATTGAAGGGGTAGTATTC
ATCATTATCACCCCGGTGCTGCTGTTCACCTCCTGGTGGCTGTGGCGCAAAAAAGCTATCGACCGTACCACCCTGCTGCT
GGGTCTGCTGCCGCCGTTCTATGTCGTCGCCGCGGTGCTGGTGCAGTTGTCGATCCATGGGATTATCCCGTTCCATATGG
CGATCTATTCCCTCTGGCAGTACGCGCTGATCGTCCACATCATTACGGTGCTGATCATTGCCATTCTGCGGGTGCGTGCT
GAAAACCGCCAGCTGGAGCAGAAGCAGCGCCTGGCGCGCGAACTGCAGATTGAGCGTGAAGCCAGCTTCCACCAGCGGCA
GTTTATGGGCATGGTGGCGCACGAATTCCGCACCCCGCTGGCGGTGATCCAGGCGGCGCTGGAGAATCTTCGCCTCTCGG
CGGCCTCGACCAGCCAGGAGGCGCGCTTCGATCGCATTGGCCGCGCCGCCACCCGCCTGGTGCAGCTCACCGATAACTGC
CTTGCCGACGCCCGGCTCGCCTCCCACGATCTGCACGTCGAGCGCCAGCAGACCGCCCTGCTGACGGTGATCAACATGGC
CGCCTCGGTGGTGGCCATCTCCCATGATCACTACCTGAACATCCGCCAGCACGGCGCGGTGGAAAGCCCGCAGCTGCAGG
CCGATGCCGGCCTGCTGTGCATCGCCATCGCTAATCTGCTGGATAACGCCGTCAAGTATTCGCCCCCCGGTGAAATCGCC
ATCGATATTCATTCCGATGCCGGGCAAACGGAGCTACGCATTCGCGACCACGGCCCGGGACTCCCCGCCGGACAGGCGGA
ACTGATCTTTGAGCGCTACCGCCGCGGCGAGCACACATCGCCGGTGCCAGGCGGCACCGGTCTCGGACTGTATGTTGCGC
GTCAGATAGTGCAGGCTCATGATGGCAAACTGTGGCTGGCCGAGCATGGCCCGGACGGCTGCACCTTTATTCTCACCCTC
CCCACGGTTGCTTAA

Upstream 100 bases:

>100_bases
GTCCACTCTTCCCCATTTCAGGGGGCGTATTATCCATACCGTAGCCAGATGTCTGCGGTCTGTATCGTTGGCTTGCCGCA
AGGGGGCGTGATTGAAAAGG

Downstream 100 bases:

>100_bases
GAGGAGAACGACGTATGGCTTTACGGCTGGCGATAATTGAAGATAACGCCGATCTGCTGGATGAACTGCTGGCCTGGCTG
GGCTATCGCGGCTTCGAGGT

Product: putative signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 644; Mature: 643

Protein sequence:

>644_residues
MSAIFGAVRRCRPQFLAGWLLSCGLFLLLVAPQAQAATRQVGIDIPVQWYADASGQMTLDRFAALPTDQLATTRQIPSFG
YSRKTWWLRSELPGTWFAGEPRWLQLGPSFVDHLTIYYRPLGSDAPWAQRTFGDRDGARESDLHYRESVLILPPPPTAAG
YEVVFRLQSTSTLILLASLSSAQAFVQRATADTAFWSFYFGLAAVASGVALWLALALRRRLLWGICLFSLNYPLVAALHG
FPEWFFGHAALPFQDFMISSLSLFSYATALWLHSEIFDLKKNMPRLHQLLIAAVILNLVLQVSIPLGFYGFAMQIEGVVF
IIITPVLLFTSWWLWRKKAIDRTTLLLGLLPPFYVVAAVLVQLSIHGIIPFHMAIYSLWQYALIVHIITVLIIAILRVRA
ENRQLEQKQRLARELQIEREASFHQRQFMGMVAHEFRTPLAVIQAALENLRLSAASTSQEARFDRIGRAATRLVQLTDNC
LADARLASHDLHVERQQTALLTVINMAASVVAISHDHYLNIRQHGAVESPQLQADAGLLCIAIANLLDNAVKYSPPGEIA
IDIHSDAGQTELRIRDHGPGLPAGQAELIFERYRRGEHTSPVPGGTGLGLYVARQIVQAHDGKLWLAEHGPDGCTFILTL
PTVA

Sequences:

>Translated_644_residues
MSAIFGAVRRCRPQFLAGWLLSCGLFLLLVAPQAQAATRQVGIDIPVQWYADASGQMTLDRFAALPTDQLATTRQIPSFG
YSRKTWWLRSELPGTWFAGEPRWLQLGPSFVDHLTIYYRPLGSDAPWAQRTFGDRDGARESDLHYRESVLILPPPPTAAG
YEVVFRLQSTSTLILLASLSSAQAFVQRATADTAFWSFYFGLAAVASGVALWLALALRRRLLWGICLFSLNYPLVAALHG
FPEWFFGHAALPFQDFMISSLSLFSYATALWLHSEIFDLKKNMPRLHQLLIAAVILNLVLQVSIPLGFYGFAMQIEGVVF
IIITPVLLFTSWWLWRKKAIDRTTLLLGLLPPFYVVAAVLVQLSIHGIIPFHMAIYSLWQYALIVHIITVLIIAILRVRA
ENRQLEQKQRLARELQIEREASFHQRQFMGMVAHEFRTPLAVIQAALENLRLSAASTSQEARFDRIGRAATRLVQLTDNC
LADARLASHDLHVERQQTALLTVINMAASVVAISHDHYLNIRQHGAVESPQLQADAGLLCIAIANLLDNAVKYSPPGEIA
IDIHSDAGQTELRIRDHGPGLPAGQAELIFERYRRGEHTSPVPGGTGLGLYVARQIVQAHDGKLWLAEHGPDGCTFILTL
PTVA
>Mature_643_residues
SAIFGAVRRCRPQFLAGWLLSCGLFLLLVAPQAQAATRQVGIDIPVQWYADASGQMTLDRFAALPTDQLATTRQIPSFGY
SRKTWWLRSELPGTWFAGEPRWLQLGPSFVDHLTIYYRPLGSDAPWAQRTFGDRDGARESDLHYRESVLILPPPPTAAGY
EVVFRLQSTSTLILLASLSSAQAFVQRATADTAFWSFYFGLAAVASGVALWLALALRRRLLWGICLFSLNYPLVAALHGF
PEWFFGHAALPFQDFMISSLSLFSYATALWLHSEIFDLKKNMPRLHQLLIAAVILNLVLQVSIPLGFYGFAMQIEGVVFI
IITPVLLFTSWWLWRKKAIDRTTLLLGLLPPFYVVAAVLVQLSIHGIIPFHMAIYSLWQYALIVHIITVLIIAILRVRAE
NRQLEQKQRLARELQIEREASFHQRQFMGMVAHEFRTPLAVIQAALENLRLSAASTSQEARFDRIGRAATRLVQLTDNCL
ADARLASHDLHVERQQTALLTVINMAASVVAISHDHYLNIRQHGAVESPQLQADAGLLCIAIANLLDNAVKYSPPGEIAI
DIHSDAGQTELRIRDHGPGLPAGQAELIFERYRRGEHTSPVPGGTGLGLYVARQIVQAHDGKLWLAEHGPDGCTFILTLP
TVA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=30.7053941908714, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=25.6809338521401, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=25.296442687747, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789149, Length=245, Percent_Identity=27.7551020408163, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790861, Length=222, Percent_Identity=27.9279279279279, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1787374, Length=225, Percent_Identity=28, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788393, Length=223, Percent_Identity=27.3542600896861, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786600, Length=237, Percent_Identity=24.0506329113924, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790436, Length=263, Percent_Identity=26.2357414448669, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790551, Length=227, Percent_Identity=29.9559471365639, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=249, Percent_Identity=23.6947791164659, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786783, Length=240, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71756; Mature: 71625

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIFGAVRRCRPQFLAGWLLSCGLFLLLVAPQAQAATRQVGIDIPVQWYADASGQMTLD
CCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCEEHH
RFAALPTDQLATTRQIPSFGYSRKTWWLRSELPGTWFAGEPRWLQLGPSFVDHLTIYYRP
HHHCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCEECCCCCEEEECHHHHHCEEEEEEE
LGSDAPWAQRTFGDRDGARESDLHYRESVLILPPPPTAAGYEVVFRLQSTSTLILLASLS
CCCCCCHHHHHCCCCCCCCCCCCHHHCEEEEECCCCCCCCEEEEEEEECCCEEEEEEHHH
SAQAFVQRATADTAFWSFYFGLAAVASGVALWLALALRRRLLWGICLFSLNYPLVAALHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
FPEWFFGHAALPFQDFMISSLSLFSYATALWLHSEIFDLKKNMPRLHQLLIAAVILNLVL
CHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
QVSIPLGFYGFAMQIEGVVFIIITPVLLFTSWWLWRKKAIDRTTLLLGLLPPFYVVAAVL
HHHCCCCHHHHHEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VQLSIHGIIPFHMAIYSLWQYALIVHIITVLIIAILRVRAENRQLEQKQRLARELQIERE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASFHQRQFMGMVAHEFRTPLAVIQAALENLRLSAASTSQEARFDRIGRAATRLVQLTDNC
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
LADARLASHDLHVERQQTALLTVINMAASVVAISHDHYLNIRQHGAVESPQLQADAGLLC
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCEEEHHHCCCCCCCCCCCCCCHHH
IAIANLLDNAVKYSPPGEIAIDIHSDAGQTELRIRDHGPGLPAGQAELIFERYRRGEHTS
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCC
PVPGGTGLGLYVARQIVQAHDGKLWLAEHGPDGCTFILTLPTVA
CCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCC
>Mature Secondary Structure 
SAIFGAVRRCRPQFLAGWLLSCGLFLLLVAPQAQAATRQVGIDIPVQWYADASGQMTLD
CHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCEEHH
RFAALPTDQLATTRQIPSFGYSRKTWWLRSELPGTWFAGEPRWLQLGPSFVDHLTIYYRP
HHHCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCEECCCCCEEEECHHHHHCEEEEEEE
LGSDAPWAQRTFGDRDGARESDLHYRESVLILPPPPTAAGYEVVFRLQSTSTLILLASLS
CCCCCCHHHHHCCCCCCCCCCCCHHHCEEEEECCCCCCCCEEEEEEEECCCEEEEEEHHH
SAQAFVQRATADTAFWSFYFGLAAVASGVALWLALALRRRLLWGICLFSLNYPLVAALHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
FPEWFFGHAALPFQDFMISSLSLFSYATALWLHSEIFDLKKNMPRLHQLLIAAVILNLVL
CHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
QVSIPLGFYGFAMQIEGVVFIIITPVLLFTSWWLWRKKAIDRTTLLLGLLPPFYVVAAVL
HHHCCCCHHHHHEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VQLSIHGIIPFHMAIYSLWQYALIVHIITVLIIAILRVRAENRQLEQKQRLARELQIERE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASFHQRQFMGMVAHEFRTPLAVIQAALENLRLSAASTSQEARFDRIGRAATRLVQLTDNC
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
LADARLASHDLHVERQQTALLTVINMAASVVAISHDHYLNIRQHGAVESPQLQADAGLLC
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCEEEHHHCCCCCCCCCCCCCCHHH
IAIANLLDNAVKYSPPGEIAIDIHSDAGQTELRIRDHGPGLPAGQAELIFERYRRGEHTS
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCC
PVPGGTGLGLYVARQIVQAHDGKLWLAEHGPDGCTFILTLPTVA
CCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]