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The map label for this gene is yegH [H]

Identifier: 152971055

GI number: 152971055

Start: 2749265

End: 2750893

Strand: Direct

Name: yegH [H]

Synonym: KPN_02516

Alternate gene names: 152971055

Gene position: 2749265-2750893 (Clockwise)

Preceding gene: 152971037

Following gene: 152971060

Centisome position: 51.73

GC content: 56.91

Gene sequence:

>1629_bases
ATGATCGTGGTAACACATACCGCAGTCGTACAGGTTTTAATGCATATGGAATGGATTGCCGATCCGTCAATCTGGGCAGG
TCTCGTCACGCTGGTGGTTATCGAACTGGTGTTAGGTATCGATAACCTGGTCTTTATCGCTATCCTCGCCGAGAAGCTCC
CTCCCGCCCAGCGCGACCGCGCGCGGATCACTGGCCTGATGCTGGCGATGGTCATGCGTCTCCTGCTGCTGGCTTCTATC
TCCTGGCTGGTCACCCTGACCAAACCTCTGATTGTTTTTCACGACTTCAGCTTTAGCGCCCGCGATTTGATTATGCTGTT
TGGCGGCCTGTTTCTGCTGTTTAAAGCGACCGTCGAGCTTAATGAGCGGCTGGAGGGGAAAGACAGCGATAACCCCACCC
AGCGCAAAGGGGCGAAATTCTGGGCCGTCGTGGCGCAGATCGTGGTGCTCGACGCCATCTTCTCGCTTGACTCGGTGATC
ACCGCCGTCGGCATGGTCGATCACCTGGCGGTGATGATGGCCGCGGTGGTTATCGCCATCAGCCTGATGCTGATGGCCAG
CAAGGCGCTGACGCGCTTCGTTAACAGCCACCCGACCATCGTGATACTCTGTCTGAGCTTCCTGCTGATGATCGGCTTCA
GTCTGATTGCTGAAGGCTTCAGCTTTATTATTCCGAAAGGCTATCTATATGCGGCCATTGGCTTCTCGGTCATGATTGAA
GCGCTTAACCAGCTGGCGCAGTTTAACCGCCGTCGCTTCCTCTCCGCCAATATGACGCTGCGTCAGCGCACTACCGAGGC
GGTGATGAATCTGCTGAGCGGGCAGAAAGAAAAAGCTGAACTGGATGCTGACACGGCGTCGCTGGTCGCCGATCAGGATC
AACATCCACTGTTTAATCCGCAGGAAAGACTGATGATTGAGCGGGTGCTGAACCTTAATCAGCGCAGCGTCAGCAGTATT
ATGACGTCGCGCCATGATATCGAGCGCATCAACCTCAGCGCGCCGGAGGAAGAGATCCGCAGCCTGGTGGAGAAAAATCA
GCATACCCGTCTGGTGGTCACCGGCGGGAAAGATAATGAAGATCTGCTGGGGGTGGTGCATGTTATTGACCTGCTCCAGC
AGTCCCTGCGTCAGGAGCCGCTGGATCTGCAGGCGCTGGTGCGTCAACCGCTGGTCTTCCCGGAGGGCCTGCCGCTCCTC
TCGGCGCTCGAGCAGTTCCGCCAGGCCCGCACCCATTTTGCCTTTGTGGTCGATGAGTTTGGTTCCGTCGAGGGGATTGT
GACCCTCAGCGACGTGATGGAGACCATCGCCGGCAATCTGCCCAATGAGGTGGAGGAGATCGATGCCCGGCACGATATTC
AGCATCATCAGGACGGTTCATGGACGGTCAATGGCCATATGCCGCTGGAGGACCTGGTGCAGTACGTTCCGCTGCCGCTG
GATGATAAACGGGAGTACCACACCGTCGCCGGTCTGCTGATGGAGTATTTGCAGCATGTGCCGCAGGTGGGGGAAACCAT
TGAGATTGACGGTTATACGCTGCGCACGCTGCAGGTCGACAGCCATCGGGTACAGAAGGTGCAGATCGTCCCGCCGGTAA
AGCAGGATGAGCTGGATTATGAGGTGTAA

Upstream 100 bases:

>100_bases
GGAACATAATTCTTATCGGTTCGCTTAATCCGCTGGAAATATATCCACCCACGGCAGGGCGATATCCGCGTCGTTATTGC
ATTTTAGACTCATCTTATCC

Downstream 100 bases:

>100_bases
TCGTCAGGCATAAAACGGCCCGGGGTATCCCGGGCCGTAAAATTGATAGCCAGGTATCCTGTTTAATGCCTGATGGCGCT
TCGCTTATCAGGCCTACGGG

Product: putative transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MIVVTHTAVVQVLMHMEWIADPSIWAGLVTLVVIELVLGIDNLVFIAILAEKLPPAQRDRARITGLMLAMVMRLLLLASI
SWLVTLTKPLIVFHDFSFSARDLIMLFGGLFLLFKATVELNERLEGKDSDNPTQRKGAKFWAVVAQIVVLDAIFSLDSVI
TAVGMVDHLAVMMAAVVIAISLMLMASKALTRFVNSHPTIVILCLSFLLMIGFSLIAEGFSFIIPKGYLYAAIGFSVMIE
ALNQLAQFNRRRFLSANMTLRQRTTEAVMNLLSGQKEKAELDADTASLVADQDQHPLFNPQERLMIERVLNLNQRSVSSI
MTSRHDIERINLSAPEEEIRSLVEKNQHTRLVVTGGKDNEDLLGVVHVIDLLQQSLRQEPLDLQALVRQPLVFPEGLPLL
SALEQFRQARTHFAFVVDEFGSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQHHQDGSWTVNGHMPLEDLVQYVPLPL
DDKREYHTVAGLLMEYLQHVPQVGETIEIDGYTLRTLQVDSHRVQKVQIVPPVKQDELDYEV

Sequences:

>Translated_542_residues
MIVVTHTAVVQVLMHMEWIADPSIWAGLVTLVVIELVLGIDNLVFIAILAEKLPPAQRDRARITGLMLAMVMRLLLLASI
SWLVTLTKPLIVFHDFSFSARDLIMLFGGLFLLFKATVELNERLEGKDSDNPTQRKGAKFWAVVAQIVVLDAIFSLDSVI
TAVGMVDHLAVMMAAVVIAISLMLMASKALTRFVNSHPTIVILCLSFLLMIGFSLIAEGFSFIIPKGYLYAAIGFSVMIE
ALNQLAQFNRRRFLSANMTLRQRTTEAVMNLLSGQKEKAELDADTASLVADQDQHPLFNPQERLMIERVLNLNQRSVSSI
MTSRHDIERINLSAPEEEIRSLVEKNQHTRLVVTGGKDNEDLLGVVHVIDLLQQSLRQEPLDLQALVRQPLVFPEGLPLL
SALEQFRQARTHFAFVVDEFGSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQHHQDGSWTVNGHMPLEDLVQYVPLPL
DDKREYHTVAGLLMEYLQHVPQVGETIEIDGYTLRTLQVDSHRVQKVQIVPPVKQDELDYEV
>Mature_542_residues
MIVVTHTAVVQVLMHMEWIADPSIWAGLVTLVVIELVLGIDNLVFIAILAEKLPPAQRDRARITGLMLAMVMRLLLLASI
SWLVTLTKPLIVFHDFSFSARDLIMLFGGLFLLFKATVELNERLEGKDSDNPTQRKGAKFWAVVAQIVVLDAIFSLDSVI
TAVGMVDHLAVMMAAVVIAISLMLMASKALTRFVNSHPTIVILCLSFLLMIGFSLIAEGFSFIIPKGYLYAAIGFSVMIE
ALNQLAQFNRRRFLSANMTLRQRTTEAVMNLLSGQKEKAELDADTASLVADQDQHPLFNPQERLMIERVLNLNQRSVSSI
MTSRHDIERINLSAPEEEIRSLVEKNQHTRLVVTGGKDNEDLLGVVHVIDLLQQSLRQEPLDLQALVRQPLVFPEGLPLL
SALEQFRQARTHFAFVVDEFGSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQHHQDGSWTVNGHMPLEDLVQYVPLPL
DDKREYHTVAGLLMEYLQHVPQVGETIEIDGYTLRTLQVDSHRVQKVQIVPPVKQDELDYEV

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=338, Percent_Identity=21.301775147929, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI87082033, Length=527, Percent_Identity=84.2504743833017, Blast_Score=886, Evalue=0.0,
Organism=Escherichia coli, GI1788119, Length=528, Percent_Identity=49.8106060606061, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1789197, Length=230, Percent_Identity=51.304347826087, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI1790664, Length=232, Percent_Identity=30.1724137931034, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1786879, Length=254, Percent_Identity=30.3149606299213, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI145693175, Length=233, Percent_Identity=25.3218884120172, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 60764; Mature: 60764

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVVTHTAVVQVLMHMEWIADPSIWAGLVTLVVIELVLGIDNLVFIAILAEKLPPAQRDR
CEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ARITGLMLAMVMRLLLLASISWLVTLTKPLIVFHDFSFSARDLIMLFGGLFLLFKATVEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHH
NERLEGKDSDNPTQRKGAKFWAVVAQIVVLDAIFSLDSVITAVGMVDHLAVMMAAVVIAI
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLMLMASKALTRFVNSHPTIVILCLSFLLMIGFSLIAEGFSFIIPKGYLYAAIGFSVMIE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHH
ALNQLAQFNRRRFLSANMTLRQRTTEAVMNLLSGQKEKAELDADTASLVADQDQHPLFNP
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHCCCCCCCCCCH
QERLMIERVLNLNQRSVSSIMTSRHDIERINLSAPEEEIRSLVEKNQHTRLVVTGGKDNE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCH
DLLGVVHVIDLLQQSLRQEPLDLQALVRQPLVFPEGLPLLSALEQFRQARTHFAFVVDEF
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQHHQDGSWTVNGHMPLEDLVQYVPLPL
CCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCCC
DDKREYHTVAGLLMEYLQHVPQVGETIEIDGYTLRTLQVDSHRVQKVQIVPPVKQDELDY
CCCHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEECCHHCEEEEECCCCCCCCCCC
EV
CC
>Mature Secondary Structure
MIVVTHTAVVQVLMHMEWIADPSIWAGLVTLVVIELVLGIDNLVFIAILAEKLPPAQRDR
CEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ARITGLMLAMVMRLLLLASISWLVTLTKPLIVFHDFSFSARDLIMLFGGLFLLFKATVEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHH
NERLEGKDSDNPTQRKGAKFWAVVAQIVVLDAIFSLDSVITAVGMVDHLAVMMAAVVIAI
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLMLMASKALTRFVNSHPTIVILCLSFLLMIGFSLIAEGFSFIIPKGYLYAAIGFSVMIE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHH
ALNQLAQFNRRRFLSANMTLRQRTTEAVMNLLSGQKEKAELDADTASLVADQDQHPLFNP
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHCCCCCCCCCCH
QERLMIERVLNLNQRSVSSIMTSRHDIERINLSAPEEEIRSLVEKNQHTRLVVTGGKDNE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCCCCH
DLLGVVHVIDLLQQSLRQEPLDLQALVRQPLVFPEGLPLLSALEQFRQARTHFAFVVDEF
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQHHQDGSWTVNGHMPLEDLVQYVPLPL
CCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCCC
DDKREYHTVAGLLMEYLQHVPQVGETIEIDGYTLRTLQVDSHRVQKVQIVPPVKQDELDY
CCCHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEECCHHCEEEEECCCCCCCCCCC
EV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]