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The map label for this gene is lpsJ [H]

Identifier: 152970603

GI number: 152970603

Start: 2248512

End: 2249168

Strand: Direct

Name: lpsJ [H]

Synonym: KPN_02054

Alternate gene names: 152970603

Gene position: 2248512-2249168 (Clockwise)

Preceding gene: 152970602

Following gene: 152970604

Centisome position: 42.3

GC content: 62.56

Gene sequence:

>657_bases
ATGCTGACCCGTGAACAAATGGCGATGCGCGTCGCCCAGGAGCTGCGCGACGGCGACTACGTCAACCTCGGGATCGGTAT
CCCGACGCTGGTGGCCAACTACATTCCCGCCGGCATTGAAGTGATGCTCCAGTCGGAGAACGGCCTGCTGGGGATGGGCG
AATTTCCCGATGAGGAAACCATCGACGCCGACATGATTAACGCCGGTAAACAAACCGTCACCGCGCAAACCGGGGCGGCG
ATCTTCGATTCCGCCCAGTCGTTCGCCATGATCCGCGGCGGCCACGTCGACCTGACCGTTCTTGGCGCCTTTGAGGTCGA
CGTCGCGGGCAACATCGCCTCATGGATGATCCCTGGAAAAATGGTCAAGGGGATGGGCGGCGCCATGGACCTGGTGGCCG
GCGCGCAGAACATCATCGTGGTGATGACCCACGCCTCAAAAAACGGCGAATCCAAACTGCTGCCGCAGTGCACCCTGCCG
CTCACCGGCGTGGCCTGTATTCGCCGGGTACTCACCGATCTGGCCCTGCTGGAGATTGTCGACGGCGCGTTTGTCCTGCG
CGAAGTGGCCCCGGGGGTCAGCCCCGACGAGGTGATACGTAAAACGGCGGGACGGCTGATCGTCGCCGACGACGTGCGCG
AAATGCGCTTCAGTTAA

Upstream 100 bases:

>100_bases
TCCGCCATCCATACTCCGGGGATCTATGTCGACCGGCTGATCGTCGGGCAATTCGAAAAACGTGTTGAACAGCGCACCCT
GCGCGCCGGAGGACACTGAG

Downstream 100 bases:

>100_bases
GGAGAGACCATGACCGATATTGCCATTGTTGCTGCAGTACGCACCCCGGTAGGCAGCTTTCACGGCGCCTTCGCCCCTCT
TTCCGCCGTCGACCTCGGCG

Product: putative acetyl-CoA:acetoacetyl-CoA transferase beta subunit

Products: NA

Alternate protein names: OXCT B; Succinyl CoA:3-oxoacid CoA-transferase [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MLTREQMAMRVAQELRDGDYVNLGIGIPTLVANYIPAGIEVMLQSENGLLGMGEFPDEETIDADMINAGKQTVTAQTGAA
IFDSAQSFAMIRGGHVDLTVLGAFEVDVAGNIASWMIPGKMVKGMGGAMDLVAGAQNIIVVMTHASKNGESKLLPQCTLP
LTGVACIRRVLTDLALLEIVDGAFVLREVAPGVSPDEVIRKTAGRLIVADDVREMRFS

Sequences:

>Translated_218_residues
MLTREQMAMRVAQELRDGDYVNLGIGIPTLVANYIPAGIEVMLQSENGLLGMGEFPDEETIDADMINAGKQTVTAQTGAA
IFDSAQSFAMIRGGHVDLTVLGAFEVDVAGNIASWMIPGKMVKGMGGAMDLVAGAQNIIVVMTHASKNGESKLLPQCTLP
LTGVACIRRVLTDLALLEIVDGAFVLREVAPGVSPDEVIRKTAGRLIVADDVREMRFS
>Mature_218_residues
MLTREQMAMRVAQELRDGDYVNLGIGIPTLVANYIPAGIEVMLQSENGLLGMGEFPDEETIDADMINAGKQTVTAQTGAA
IFDSAQSFAMIRGGHVDLTVLGAFEVDVAGNIASWMIPGKMVKGMGGAMDLVAGAQNIIVVMTHASKNGESKLLPQCTLP
LTGVACIRRVLTDLALLEIVDGAFVLREVAPGVSPDEVIRKTAGRLIVADDVREMRFS

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=215, Percent_Identity=49.7674418604651, Blast_Score=216, Evalue=1e-56,
Organism=Homo sapiens, GI11545841, Length=215, Percent_Identity=47.4418604651163, Blast_Score=211, Evalue=4e-55,
Organism=Escherichia coli, GI1788552, Length=216, Percent_Identity=50.9259259259259, Blast_Score=223, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI17531517, Length=215, Percent_Identity=51.6279069767442, Blast_Score=221, Evalue=3e-58,
Organism=Drosophila melanogaster, GI21358325, Length=214, Percent_Identity=51.8691588785047, Blast_Score=229, Evalue=8e-61,
Organism=Drosophila melanogaster, GI24655794, Length=214, Percent_Identity=51.8691588785047, Blast_Score=229, Evalue=1e-60,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 23160; Mature: 23160

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS01274 COA_TRANSF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTREQMAMRVAQELRDGDYVNLGIGIPTLVANYIPAGIEVMLQSENGLLGMGEFPDEET
CCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCC
IDADMINAGKQTVTAQTGAAIFDSAQSFAMIRGGHVDLTVLGAFEVDVAGNIASWMIPGK
CCHHHHCCCCCEEECCCCHHHHHHHHHHHEEECCCEEEEEEEEEEEEECCCHHHHCCCHH
MVKGMGGAMDLVAGAQNIIVVMTHASKNGESKLLPQCTLPLTGVACIRRVLTDLALLEIV
HHHCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DGAFVLREVAPGVSPDEVIRKTAGRLIVADDVREMRFS
HHHHHHHHHCCCCCHHHHHHHHHCCEEEECCHHHHCCC
>Mature Secondary Structure
MLTREQMAMRVAQELRDGDYVNLGIGIPTLVANYIPAGIEVMLQSENGLLGMGEFPDEET
CCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCC
IDADMINAGKQTVTAQTGAAIFDSAQSFAMIRGGHVDLTVLGAFEVDVAGNIASWMIPGK
CCHHHHCCCCCEEECCCCHHHHHHHHHHHEEECCCEEEEEEEEEEEEECCCHHHHCCCHH
MVKGMGGAMDLVAGAQNIIVVMTHASKNGESKLLPQCTLPLTGVACIRRVLTDLALLEIV
HHHCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DGAFVLREVAPGVSPDEVIRKTAGRLIVADDVREMRFS
HHHHHHHHHCCCCCHHHHHHHHHCCEEEECCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134 [H]