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The map label for this gene is bglC [H]

Identifier: 152970513

GI number: 152970513

Start: 2158735

End: 2160105

Strand: Direct

Name: bglC [H]

Synonym: KPN_01961

Alternate gene names: 152970513

Gene position: 2158735-2160105 (Clockwise)

Preceding gene: 152970512

Following gene: 152970514

Centisome position: 40.61

GC content: 57.55

Gene sequence:

>1371_bases
ATGGCCGCTTTTCCGCACAATTTCTTATGGGGTGCCGCTACCGCAGCGTATCAGGTTGAGGGAGGACACGACGCCGACGG
TAAAGGACCGTCAATCTGGGATATCTACTCTCATCTGCCGGGTACCACCTTTGAAGGCACCACCGGCGATATTGCCGTCG
ACCACTATCACCGTTTTCGCGAAGACGTGGCGTTAATGGCCGAAATGGGCCTGCAAAGCTATCGATTCTCCATCTCCTGG
CCCCGCCTGCTGCCCGCCGGGCGCGGTAAGGTGAATGAAGCGGGAGTCCAGTTTTACAGCGATCTGATCGACGAACTGCT
GGCGCACAATATTGAGCCGATGATCACCCTCTATCACTGGGATCTGCCGCAGGCCCTGCAGGATGAGGGCGGCTGGGAAG
CGCGCACTACCGCCGAGGCCTTCGCCGAGTACGCCCGCCTGTGCTATGCGCGCTTTGGTTCACGGGTGAAGCTGTGGGCT
ACCTTCAACGAAACCATTGTCTTCATTGGGCACGGCTACATTAACGGCCTCCATCCCCCGGCGGTCCGCGATCCGGCGCG
TGCTATTCAGGCCTGCCACCACGTATTTATCGCCCATGCGCTGGCGGTGAAGGCCTTTCGCGAGATGGCTGTGGCCGGCG
AGATTGGCTTCGTCAACGTACTGCAACCGCATACCCCGCTCACCGACAGCGAGGCGGACATTAAGGCCACCGAACTGGCT
GACGCCATCCATACTCACTGGCTGTACGATCCGGTGCTGAAAGGCACCTATCCTGCCGACCTGCTGGCGCAGACCCAGGC
GCTGTGGGGGGTACCTCGCTTTGCTCCAGGCGACGACGCGCTGCTCCGTGACAACCGCTGCGACTTTATCGGTCTGAATT
ACTATCGCCGGGAAACGGTATCTGCCCAGCCGCCTGAGATCGCTACCGGCGGTGAGCCTGGCGTGGAGGGATTATTCTAT
TTCGTGCGTAATCCCCAGAGTACATATACCGAATGGGGCTGGGAAATCTGGCCGCAGGGGCTAACTGACGGCATTATGAT
GATTAAGGCGCGCTATGGCGATATTCCGATATATATCACCGAGAATGGCCTCGGCGCGAAGGACCCGATTATTGACGGGG
AAGTGGTCGACGACCCGCGGATTGATTATCTCAGCAGCCATATTGGCGCCCTCGAAAAAGCGCTGGCGCTGGGGGCAGAT
GTGCGCGGCTATTACCCCTGGTCATTTATCGATCTGCTGAGCTGGCTCAACGGCTATCAAAAGCAATATGGTTTTGTCTA
TGTCGATCACCAGCAAAATCTGGCGCGGAAACGAAAGAAGAGTTTTTATTGGTACAAATCTGTTATTGCCAGTCACGGCG
AACAGCGTTAA

Upstream 100 bases:

>100_bases
GTGACCCGCCTCGCAACTGTGCAACCGGTTTCAGAAACCGGTTGCACGTATGCTCGCGCTTTTATTACACTCCCTTTATC
ATCAGACAGGGAGCTTTTTC

Downstream 100 bases:

>100_bases
TCTTCTCTTGCGGGCGCCATTCGGCGCCCGGTCTGATTTTAGAATATTCTTAAACTTCTCCCTGCTCTTCAAGGCTGGCT
TTGCCCCTTGTCATGGGTTT

Product: 6-phospho-beta-glucosidase A

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MAAFPHNFLWGAATAAYQVEGGHDADGKGPSIWDIYSHLPGTTFEGTTGDIAVDHYHRFREDVALMAEMGLQSYRFSISW
PRLLPAGRGKVNEAGVQFYSDLIDELLAHNIEPMITLYHWDLPQALQDEGGWEARTTAEAFAEYARLCYARFGSRVKLWA
TFNETIVFIGHGYINGLHPPAVRDPARAIQACHHVFIAHALAVKAFREMAVAGEIGFVNVLQPHTPLTDSEADIKATELA
DAIHTHWLYDPVLKGTYPADLLAQTQALWGVPRFAPGDDALLRDNRCDFIGLNYYRRETVSAQPPEIATGGEPGVEGLFY
FVRNPQSTYTEWGWEIWPQGLTDGIMMIKARYGDIPIYITENGLGAKDPIIDGEVVDDPRIDYLSSHIGALEKALALGAD
VRGYYPWSFIDLLSWLNGYQKQYGFVYVDHQQNLARKRKKSFYWYKSVIASHGEQR

Sequences:

>Translated_456_residues
MAAFPHNFLWGAATAAYQVEGGHDADGKGPSIWDIYSHLPGTTFEGTTGDIAVDHYHRFREDVALMAEMGLQSYRFSISW
PRLLPAGRGKVNEAGVQFYSDLIDELLAHNIEPMITLYHWDLPQALQDEGGWEARTTAEAFAEYARLCYARFGSRVKLWA
TFNETIVFIGHGYINGLHPPAVRDPARAIQACHHVFIAHALAVKAFREMAVAGEIGFVNVLQPHTPLTDSEADIKATELA
DAIHTHWLYDPVLKGTYPADLLAQTQALWGVPRFAPGDDALLRDNRCDFIGLNYYRRETVSAQPPEIATGGEPGVEGLFY
FVRNPQSTYTEWGWEIWPQGLTDGIMMIKARYGDIPIYITENGLGAKDPIIDGEVVDDPRIDYLSSHIGALEKALALGAD
VRGYYPWSFIDLLSWLNGYQKQYGFVYVDHQQNLARKRKKSFYWYKSVIASHGEQR
>Mature_455_residues
AAFPHNFLWGAATAAYQVEGGHDADGKGPSIWDIYSHLPGTTFEGTTGDIAVDHYHRFREDVALMAEMGLQSYRFSISWP
RLLPAGRGKVNEAGVQFYSDLIDELLAHNIEPMITLYHWDLPQALQDEGGWEARTTAEAFAEYARLCYARFGSRVKLWAT
FNETIVFIGHGYINGLHPPAVRDPARAIQACHHVFIAHALAVKAFREMAVAGEIGFVNVLQPHTPLTDSEADIKATELAD
AIHTHWLYDPVLKGTYPADLLAQTQALWGVPRFAPGDDALLRDNRCDFIGLNYYRRETVSAQPPEIATGGEPGVEGLFYF
VRNPQSTYTEWGWEIWPQGLTDGIMMIKARYGDIPIYITENGLGAKDPIIDGEVVDDPRIDYLSSHIGALEKALALGADV
RGYYPWSFIDLLSWLNGYQKQYGFVYVDHQQNLARKRKKSFYWYKSVIASHGEQR

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=475, Percent_Identity=37.0526315789474, Blast_Score=280, Evalue=2e-75,
Organism=Homo sapiens, GI110681710, Length=472, Percent_Identity=34.7457627118644, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI13273313, Length=457, Percent_Identity=34.3544857768052, Blast_Score=254, Evalue=9e-68,
Organism=Homo sapiens, GI28376633, Length=463, Percent_Identity=30.2375809935205, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI24497614, Length=478, Percent_Identity=30.7531380753138, Blast_Score=185, Evalue=9e-47,
Organism=Homo sapiens, GI190360571, Length=98, Percent_Identity=52.0408163265306, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI2367174, Length=487, Percent_Identity=36.5503080082135, Blast_Score=291, Evalue=5e-80,
Organism=Escherichia coli, GI1789070, Length=483, Percent_Identity=37.2670807453416, Blast_Score=267, Evalue=9e-73,
Organism=Escherichia coli, GI2367270, Length=470, Percent_Identity=37.4468085106383, Blast_Score=261, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI17552856, Length=469, Percent_Identity=33.0490405117271, Blast_Score=248, Evalue=5e-66,
Organism=Caenorhabditis elegans, GI17539390, Length=477, Percent_Identity=32.0754716981132, Blast_Score=232, Evalue=4e-61,
Organism=Drosophila melanogaster, GI21356577, Length=453, Percent_Identity=33.3333333333333, Blast_Score=248, Evalue=7e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 51231; Mature: 51100

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAFPHNFLWGAATAAYQVEGGHDADGKGPSIWDIYSHLPGTTFEGTTGDIAVDHYHRFR
CCCCCCCHHHHCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEHHHHHHHH
EDVALMAEMGLQSYRFSISWPRLLPAGRGKVNEAGVQFYSDLIDELLAHNIEPMITLYHW
HHHHHHHHHCHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
DLPQALQDEGGWEARTTAEAFAEYARLCYARFGSRVKLWATFNETIVFIGHGYINGLHPP
CCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEECCCCCCCCCC
AVRDPARAIQACHHVFIAHALAVKAFREMAVAGEIGFVNVLQPHTPLTDSEADIKATELA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHH
DAIHTHWLYDPVLKGTYPADLLAQTQALWGVPRFAPGDDALLRDNRCDFIGLNYYRRETV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEECCCCCCEEECCHHHHCCC
SAQPPEIATGGEPGVEGLFYFVRNPQSTYTEWGWEIWPQGLTDGIMMIKARYGDIPIYIT
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHCCCEECCCCCCCCEEEEEEECCCEEEEEE
ENGLGAKDPIIDGEVVDDPRIDYLSSHIGALEKALALGADVRGYYPWSFIDLLSWLNGYQ
CCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KQYGFVYVDHQQNLARKRKKSFYWYKSVIASHGEQR
HHCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AAFPHNFLWGAATAAYQVEGGHDADGKGPSIWDIYSHLPGTTFEGTTGDIAVDHYHRFR
CCCCCCHHHHCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEHHHHHHHH
EDVALMAEMGLQSYRFSISWPRLLPAGRGKVNEAGVQFYSDLIDELLAHNIEPMITLYHW
HHHHHHHHHCHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
DLPQALQDEGGWEARTTAEAFAEYARLCYARFGSRVKLWATFNETIVFIGHGYINGLHPP
CCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEECCCCCCCCCC
AVRDPARAIQACHHVFIAHALAVKAFREMAVAGEIGFVNVLQPHTPLTDSEADIKATELA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHH
DAIHTHWLYDPVLKGTYPADLLAQTQALWGVPRFAPGDDALLRDNRCDFIGLNYYRRETV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCEECCCCCCEEECCHHHHCCC
SAQPPEIATGGEPGVEGLFYFVRNPQSTYTEWGWEIWPQGLTDGIMMIKARYGDIPIYIT
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHCCCEECCCCCCCCEEEEEEECCCEEEEEE
ENGLGAKDPIIDGEVVDDPRIDYLSSHIGALEKALALGADVRGYYPWSFIDLLSWLNGYQ
CCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KQYGFVYVDHQQNLARKRKKSFYWYKSVIASHGEQR
HHCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]