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The map label for this gene is yyaJ [H]

Identifier: 152970374

GI number: 152970374

Start: 2014216

End: 2015622

Strand: Direct

Name: yyaJ [H]

Synonym: KPN_01822

Alternate gene names: 152970374

Gene position: 2014216-2015622 (Clockwise)

Preceding gene: 152970371

Following gene: 152970380

Centisome position: 37.9

GC content: 59.84

Gene sequence:

>1407_bases
ATGTCTACCACCCAGGTTCTCGGCGAAACGCCCTATGCTTCGCCAGGACAACCGCACGCCAGCTTAACCGGACGCATTGA
TGCGCTGCCCGCCTCATTTGGGTTATGGTCGTTTATTACCCTGCTCTCACTTGGCGGCTTCTTTGAGCTCTACGATCTCT
TCCAGACCGGGTATATCAGCGCGGGCCTGCTGGCGGAGGGCATTTTCCACACCGGACAGGCGGGCATCTTCGGCATCGCC
GACCAGGCGGCCTTCGCCTCCGCCACCTTTATGGGGCTGTTTATCGGCGCCAGTCTGCTGGCGCCGCTGGCGGACAAACT
GGGCCGCCGCCTGACCTTTATGGTGGCGCTCGCCTGGTACGGTCTTTTTTCGCTGCTGATGGCGACGCAGAGTAGCGCGG
AAGGGGTGATCTTCTTCCGCTTTCTGGTGGGGATCGGCCTCGGCATTGAGCTGGTGACCATTGATACTTACCTCAGCGAA
TGGGTGCCAACCCATCTGCGCAATAAAGCCTTTGCCTTTGCCTTCTTCATCCAGTTCCTCTCGGTTCCGGCGGTGGCGCT
GATGTCCTGGATGCTGGTGCCGACCACCCTGTTCGGCCTCAGCGGCTGGCGCTGGGTGATCATCTTTGGCGCACTGTTCT
CGCTGGCGATCTGGTTTATCCGCAAAAAGCTACCGGAGTCAGCCCGCTGGCTGGAAAGCAAAGGGCGGCATGATGACGCG
CATACGGTGATGTGTGAGATGGAAGCCCGCTGCGGCCTGACGCCGTCGCCGAAGCATGCGCATGCGGCACAGAGCGTCGT
CAAACGCGGCACCTTCCGCGAAATCTGGGCGCCGCAGTATCGGCAGCGCACCCTGATGCTGATGGTGATGAACTTCTTCC
AGGCGATCGGTTTCTTCGGCTTTGGCAACTGGCTGCCGGCGCTGCTCTCCGGTCAGGGCGCCAGCATCACCCATAGCCTG
CTGTACGCCTTCTTTATCACCCTCGCCTATCCGCTGGGCTGTCTGTTCTGCACCCGCTTCGTGCATCGCTTTGAAAACAA
GTGGCAGATTGTCCTCTCCGCGCTGATGACCGTTATCTTCGGCACCCTGTTCGCTCTGCAAAACAGTCCGATCCTGTTGG
TGATCTGCGGGTTTATGATCACCTGGTCCAACGCCTGGCTGACCATCAGCTACCACGCCTACCAGGCCGAGGTCTTCCCG
ACCCATATTCGCGCCCGCGCCGTCGGCTTCTGCTACTCGTTCAGCCGGCTCTCGACCGCGGTGACCAGCATTCTGATCGG
CATTATTCTGCAATACGCCGGCACGCCGGGAGTAATTAGCTTTATCGTCGTCAGTATGCTGATGGTGATGCTGTCGGTGG
GGATCTTCGGCCCGAGAACGCGGGGCATTCGTCTGGAGAATATCTGA

Upstream 100 bases:

>100_bases
CGCTAAAGAATGTCGCTAAGGCTAAGGATTAAAAATTTAAAACTATTAACAATCAATTAACATTAGCAGGCAAACCATTC
TTCCTGAGGAACACAACACC

Downstream 100 bases:

>100_bases
TGGCGGTCGCCGCCGAGGGTGCCGGCGGCGACATATTTTATCAGTTGCGATGTTGCAGCTGGCGCTGAACCTCAATAAGC
TCCGCGATCAACTCCCGCGC

Product: putative transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSTTQVLGETPYASPGQPHASLTGRIDALPASFGLWSFITLLSLGGFFELYDLFQTGYISAGLLAEGIFHTGQAGIFGIA
DQAAFASATFMGLFIGASLLAPLADKLGRRLTFMVALAWYGLFSLLMATQSSAEGVIFFRFLVGIGLGIELVTIDTYLSE
WVPTHLRNKAFAFAFFIQFLSVPAVALMSWMLVPTTLFGLSGWRWVIIFGALFSLAIWFIRKKLPESARWLESKGRHDDA
HTVMCEMEARCGLTPSPKHAHAAQSVVKRGTFREIWAPQYRQRTLMLMVMNFFQAIGFFGFGNWLPALLSGQGASITHSL
LYAFFITLAYPLGCLFCTRFVHRFENKWQIVLSALMTVIFGTLFALQNSPILLVICGFMITWSNAWLTISYHAYQAEVFP
THIRARAVGFCYSFSRLSTAVTSILIGIILQYAGTPGVISFIVVSMLMVMLSVGIFGPRTRGIRLENI

Sequences:

>Translated_468_residues
MSTTQVLGETPYASPGQPHASLTGRIDALPASFGLWSFITLLSLGGFFELYDLFQTGYISAGLLAEGIFHTGQAGIFGIA
DQAAFASATFMGLFIGASLLAPLADKLGRRLTFMVALAWYGLFSLLMATQSSAEGVIFFRFLVGIGLGIELVTIDTYLSE
WVPTHLRNKAFAFAFFIQFLSVPAVALMSWMLVPTTLFGLSGWRWVIIFGALFSLAIWFIRKKLPESARWLESKGRHDDA
HTVMCEMEARCGLTPSPKHAHAAQSVVKRGTFREIWAPQYRQRTLMLMVMNFFQAIGFFGFGNWLPALLSGQGASITHSL
LYAFFITLAYPLGCLFCTRFVHRFENKWQIVLSALMTVIFGTLFALQNSPILLVICGFMITWSNAWLTISYHAYQAEVFP
THIRARAVGFCYSFSRLSTAVTSILIGIILQYAGTPGVISFIVVSMLMVMLSVGIFGPRTRGIRLENI
>Mature_467_residues
STTQVLGETPYASPGQPHASLTGRIDALPASFGLWSFITLLSLGGFFELYDLFQTGYISAGLLAEGIFHTGQAGIFGIAD
QAAFASATFMGLFIGASLLAPLADKLGRRLTFMVALAWYGLFSLLMATQSSAEGVIFFRFLVGIGLGIELVTIDTYLSEW
VPTHLRNKAFAFAFFIQFLSVPAVALMSWMLVPTTLFGLSGWRWVIIFGALFSLAIWFIRKKLPESARWLESKGRHDDAH
TVMCEMEARCGLTPSPKHAHAAQSVVKRGTFREIWAPQYRQRTLMLMVMNFFQAIGFFGFGNWLPALLSGQGASITHSLL
YAFFITLAYPLGCLFCTRFVHRFENKWQIVLSALMTVIFGTLFALQNSPILLVICGFMITWSNAWLTISYHAYQAEVFPT
HIRARAVGFCYSFSRLSTAVTSILIGIILQYAGTPGVISFIVVSMLMVMLSVGIFGPRTRGIRLENI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI166064021, Length=406, Percent_Identity=27.5862068965517, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI262399383, Length=261, Percent_Identity=25.6704980842912, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI7662270, Length=261, Percent_Identity=25.6704980842912, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI216548223, Length=261, Percent_Identity=22.2222222222222, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI24308167, Length=378, Percent_Identity=22.2222222222222, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788068, Length=466, Percent_Identity=25.3218884120172, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788074, Length=396, Percent_Identity=25.7575757575758, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786229, Length=391, Percent_Identity=26.3427109974425, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI87082159, Length=356, Percent_Identity=26.9662921348315, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87082404, Length=401, Percent_Identity=24.6882793017456, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32565921, Length=378, Percent_Identity=28.3068783068783, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320595, Length=228, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19922616, Length=404, Percent_Identity=25, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 51814; Mature: 51682

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCC
>Mature Secondary Structure 
STTQVLGETPYASPGQPHASLTGRIDALPASFGLWSFITLLSLGGFFELYDLFQTGYIS
CCCCCCCCCCCCCCCCCCCHHCCCHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHH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HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]