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The map label for this gene is oxlT [H]

Identifier: 152970302

GI number: 152970302

Start: 1930853

End: 1932151

Strand: Direct

Name: oxlT [H]

Synonym: KPN_01750

Alternate gene names: 152970302

Gene position: 1930853-1932151 (Clockwise)

Preceding gene: 152970300

Following gene: 152970304

Centisome position: 36.33

GC content: 59.58

Gene sequence:

>1299_bases
ATGCGTTTCACGGAAGCCTGCTTACTGAAAACGGAGAACAACATGACGACACTCAGCGAACCGTTGGTTACCCCGAAATA
TGGCAAGTGGCGCCAGCTGGTGCTGGGCCTGATCTGTATGGCCGCCATCTCCAGTCCGCAATATGTCTGGACGCTGTTGA
CAAAACCCTTGGCCGCCAAACTTGGCGTCGGTCTGCCAGAATTGCAGGTCACCTTCTCGCTGCTGATCATCCTGCAGACC
TTCTTTTCCCCTTTTCAGGGGCGGTTAGTGGAAAAATTTGGCCCACGGCGGCTGATCGCTATTGGCACAGTGATGGCGGG
AATGAGCTGGGTGCTTTCCGCGCAGGTGAATGGCCTGGCAACGCTCTGGCTGGTTTATGGCTGCATGGGCGGCCTCGGGA
CCGGGATCGTCTACATCGGTGTTGTCGGCCTGATGGTCAAATGGTTCCCACAGCAGCGGGGATTTGCCGCCGGCGCGGTG
GCGGCGGGCTACGGGATGGGGGCCATCATAACCACCTTCCCCATCTCCCTGTCGCTGACCACTAACGGCCTTGAACATAC
GATGACGACTTTCGGGATCCTTTTCGCCCTCGTCGGCTTCCTCGCCAGTCAGGGGCTGAATCTGCCGCCGCCCGCTGTCT
CCCAGCCCGTCAGTCAGACGGTGGCGCAGAGCAGCAGATCGTTTACTTCCCGGGAAATGCTGCGCCAGCCGCTGTTCTGG
CTGATGTTCGTCATGATGGCGATGATGTCGACTTCCGGGCTGATGGTCACTTCGCAGATGGCGGTGTTCGCCGAGGATTT
CGGCATTAGCCAGGCGGTGGTGTTTGGCATGGCGGCGCTGCCGCTGGCGTTAACGATAGACCGCTTTACCAACGGCTTAA
CCCGGCCGCTGTTTGGGTTTATTTCCGACCGCTTCGGCCGCGAGCAAACCATGTTTATCGCCTTTGCGCTGGAGGGGGTA
GCGATGATGCTCTGGCTGGCGTGCCGGGAAGATCCGCTGCTGTTTGTCCTGCTCTCCGGGGTGGTGTTCTTTGGCTGGGG
GGAGATCTTCTCGCTCTTCCCGTCGACGCTCACCGATACGTTCGGCAGCGAACATGCCGCCAGCAACTATGGCTGGCTGT
ATATTTCGCAGGGCATCGGGTCAATCTTTGGCGGTCCGCTGGCGGCACTGCTCTATCAGTACACTCACGGCTGGCATGTG
GTCTTCAGCTGCGCGATTGGCCTTGATTTTGTCACCGCCGCCCTCGCGCTGTGGGTGCTAAAACCGTGGCGCGCGCGCTT
TATCCGCCAGCATAGCTAA

Upstream 100 bases:

>100_bases
TTGTATACCGCAATGTGGACAAGAACGTATGCCATATGGCCACAACAGGTCGCCAGTCTGCGGTCGCAACCTTCCCCTTT
CTGTGAGGCATCCAGGGTGG

Downstream 100 bases:

>100_bases
TCGTCCGCCGGGCAGAAGTGACGGCTCGCCCGTCACTTCACTGATATTCGCTACGCAACAGCGCGTACAGGTACTCATCG
CCCCACTCGCCTTTAAAAAA

Product: major facilitator superfamily permease

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MRFTEACLLKTENNMTTLSEPLVTPKYGKWRQLVLGLICMAAISSPQYVWTLLTKPLAAKLGVGLPELQVTFSLLIILQT
FFSPFQGRLVEKFGPRRLIAIGTVMAGMSWVLSAQVNGLATLWLVYGCMGGLGTGIVYIGVVGLMVKWFPQQRGFAAGAV
AAGYGMGAIITTFPISLSLTTNGLEHTMTTFGILFALVGFLASQGLNLPPPAVSQPVSQTVAQSSRSFTSREMLRQPLFW
LMFVMMAMMSTSGLMVTSQMAVFAEDFGISQAVVFGMAALPLALTIDRFTNGLTRPLFGFISDRFGREQTMFIAFALEGV
AMMLWLACREDPLLFVLLSGVVFFGWGEIFSLFPSTLTDTFGSEHAASNYGWLYISQGIGSIFGGPLAALLYQYTHGWHV
VFSCAIGLDFVTAALALWVLKPWRARFIRQHS

Sequences:

>Translated_432_residues
MRFTEACLLKTENNMTTLSEPLVTPKYGKWRQLVLGLICMAAISSPQYVWTLLTKPLAAKLGVGLPELQVTFSLLIILQT
FFSPFQGRLVEKFGPRRLIAIGTVMAGMSWVLSAQVNGLATLWLVYGCMGGLGTGIVYIGVVGLMVKWFPQQRGFAAGAV
AAGYGMGAIITTFPISLSLTTNGLEHTMTTFGILFALVGFLASQGLNLPPPAVSQPVSQTVAQSSRSFTSREMLRQPLFW
LMFVMMAMMSTSGLMVTSQMAVFAEDFGISQAVVFGMAALPLALTIDRFTNGLTRPLFGFISDRFGREQTMFIAFALEGV
AMMLWLACREDPLLFVLLSGVVFFGWGEIFSLFPSTLTDTFGSEHAASNYGWLYISQGIGSIFGGPLAALLYQYTHGWHV
VFSCAIGLDFVTAALALWVLKPWRARFIRQHS
>Mature_432_residues
MRFTEACLLKTENNMTTLSEPLVTPKYGKWRQLVLGLICMAAISSPQYVWTLLTKPLAAKLGVGLPELQVTFSLLIILQT
FFSPFQGRLVEKFGPRRLIAIGTVMAGMSWVLSAQVNGLATLWLVYGCMGGLGTGIVYIGVVGLMVKWFPQQRGFAAGAV
AAGYGMGAIITTFPISLSLTTNGLEHTMTTFGILFALVGFLASQGLNLPPPAVSQPVSQTVAQSSRSFTSREMLRQPLFW
LMFVMMAMMSTSGLMVTSQMAVFAEDFGISQAVVFGMAALPLALTIDRFTNGLTRPLFGFISDRFGREQTMFIAFALEGV
AMMLWLACREDPLLFVLLSGVVFFGWGEIFSLFPSTLTDTFGSEHAASNYGWLYISQGIGSIFGGPLAALLYQYTHGWHV
VFSCAIGLDFVTAALALWVLKPWRARFIRQHS

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=374, Percent_Identity=29.144385026738, Blast_Score=143, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI193209150, Length=335, Percent_Identity=25.3731343283582, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47205; Mature: 47205

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFTEACLLKTENNMTTLSEPLVTPKYGKWRQLVLGLICMAAISSPQYVWTLLTKPLAAK
CCCCHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LGVGLPELQVTFSLLIILQTFFSPFQGRLVEKFGPRRLIAIGTVMAGMSWVLSAQVNGLA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TLWLVYGCMGGLGTGIVYIGVVGLMVKWFPQQRGFAAGAVAAGYGMGAIITTFPISLSLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHCCEEEEEE
TNGLEHTMTTFGILFALVGFLASQGLNLPPPAVSQPVSQTVAQSSRSFTSREMLRQPLFW
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LMFVMMAMMSTSGLMVTSQMAVFAEDFGISQAVVFGMAALPLALTIDRFTNGLTRPLFGF
HHHHHHHHHCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ISDRFGREQTMFIAFALEGVAMMLWLACREDPLLFVLLSGVVFFGWGEIFSLFPSTLTDT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGSEHAASNYGWLYISQGIGSIFGGPLAALLYQYTHGWHVVFSCAIGLDFVTAALALWVL
CCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
KPWRARFIRQHS
HHHHHHHHHCCC
>Mature Secondary Structure
MRFTEACLLKTENNMTTLSEPLVTPKYGKWRQLVLGLICMAAISSPQYVWTLLTKPLAAK
CCCCHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LGVGLPELQVTFSLLIILQTFFSPFQGRLVEKFGPRRLIAIGTVMAGMSWVLSAQVNGLA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TLWLVYGCMGGLGTGIVYIGVVGLMVKWFPQQRGFAAGAVAAGYGMGAIITTFPISLSLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHCCEEEEEE
TNGLEHTMTTFGILFALVGFLASQGLNLPPPAVSQPVSQTVAQSSRSFTSREMLRQPLFW
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LMFVMMAMMSTSGLMVTSQMAVFAEDFGISQAVVFGMAALPLALTIDRFTNGLTRPLFGF
HHHHHHHHHCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ISDRFGREQTMFIAFALEGVAMMLWLACREDPLLFVLLSGVVFFGWGEIFSLFPSTLTDT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGSEHAASNYGWLYISQGIGSIFGGPLAALLYQYTHGWHVVFSCAIGLDFVTAALALWVL
CCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
KPWRARFIRQHS
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]