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The map label for this gene is pgtP [H]

Identifier: 152970276

GI number: 152970276

Start: 1905466

End: 1906776

Strand: Direct

Name: pgtP [H]

Synonym: KPN_01724

Alternate gene names: 152970276

Gene position: 1905466-1906776 (Clockwise)

Preceding gene: 152970271

Following gene: 152970281

Centisome position: 35.85

GC content: 55.23

Gene sequence:

>1311_bases
ATGCAGGCGCTGCTAAGCGTATTTCTGGGATACCTGGCGTACTATATCGTGCGCAATAACTTCACCTTATCCACGCCCTA
TCTGAAAGAACAGTTAGACCTCAGCGCCACGCAGATCGGTTTGCTCAGCAGCTGTATGCTCATCGCCTACGGGATCAGTA
AAGGCGTAATGAGCAGCCTCGCGGATAAAGCCAGCCCGAAAGTCTTTATGGCCTGTGGCCTGGTGCTGTGCGCTATCGTC
AACGTCGGGTTAGGATTCAGTACCGCATTCTGGGTCTTCGCTGCGCTGGTTGTCCTGAACGGCCTGTTTCAGGGTATGGG
GGTCGGCCCCTCTTTTATTACTATTGCGAACTGGTTCCCGCGCCGTGAGCGTGGCCGCGTAGGGGCGTTCTGGAACATTT
CCCATAACGTCGGCGGCGGAATTGTCGCCCCGATCGTCGGCGCCGCATTCGCCATTCTCGGCACCGAGCACTGGCAGAGC
GCCAGCTACATTGTACCGGCCTGCGTGGCGGTGGTATTCGCCATTAGCGTACTGGTGCTGGGTAAGGGTTCGCCGCGCGA
GGAAGGTCTGCCTTCGCTGGCAGAGATGATGCCGGAAGAGAAAGTGGTGCTGAAGACCAAACACGGCCAGAAAGCGCCGG
AGAACATGAGCGCATTTCAGATCTTCTGTACCTACGTACTGCGTAACAAAAACGCCTGGTATGTCTCCTTTGTGGATGTG
TTTGTCTATATGGTGCGTTTCGGCATGATCAGCTGGCTGCCAATTTACCTGCTGACGGTGAAACATTTTTCCAAAGAACA
AATGAGCGTCGCATTCCTGTTTTTTGAGTGGGCGGCGATTCCGTCTACTCTGCTGGCCGGCTGGCTCTCCGACAAGCTGT
TTAAAGGGCGCCGGATGCCGTTAGCCATAATCTGTATGACGCTAATCTTCATCTGTCTGATCGGCTACTGGAAAAGCGAA
TCGCTACTGATGGTCACGGTATTCGCGGCAATTGTGGGCTGCCTTATTTATGTCCCGCAGTTTCTGGCCTCGGTCCAGAC
CATGGAAATCGTCCCCAGCTTTGCCGTCGGTTCAGCCGTGGGTCTGCGCGGATTTATGAGCTATATCTTTGGCGCATCGT
TAGGCACCAGCCTGTTCGGCGTAATGGTCGATAAAATGGGCTGGCACGGCGGGTTCTATCTGCTGATGGGCGGGATCGTC
TGCTGCATACTCTTCTGCTACCTCTCTCATCGCGGCGCGCTGGAACTTGAGCAACAGCGTAAAATCACCGAGCAGGAAGA
GGCCCGACTGGCACTGGCTGACGCACAGTAA

Upstream 100 bases:

>100_bases
TATAAATACAGGTGACGACATGTTATCATTATTAAAAAAAGGCCCGTCGGCGAATAAAGTTCCTGCTGAGAAAATTCAGG
CAACCTATGGTCGATACCGT

Downstream 100 bases:

>100_bases
GCGCCTGAACCCGGGGGAACAAAGAGCCAGCTTGCTGGCTCTTTTGCCGTTGATAGAGGAATAGATGTCCGCGGCGGCTT
CCGACAGCGGTATAAAGCAA

Product: phosphoglycerate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGISKGVMSSLADKASPKVFMACGLVLCAIV
NVGLGFSTAFWVFAALVVLNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNISHNVGGGIVAPIVGAAFAILGTEHWQS
ASYIVPACVAVVFAISVLVLGKGSPREEGLPSLAEMMPEEKVVLKTKHGQKAPENMSAFQIFCTYVLRNKNAWYVSFVDV
FVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKLFKGRRMPLAIICMTLIFICLIGYWKSE
SLLMVTVFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGASLGTSLFGVMVDKMGWHGGFYLLMGGIV
CCILFCYLSHRGALELEQQRKITEQEEARLALADAQ

Sequences:

>Translated_436_residues
MQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGISKGVMSSLADKASPKVFMACGLVLCAIV
NVGLGFSTAFWVFAALVVLNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNISHNVGGGIVAPIVGAAFAILGTEHWQS
ASYIVPACVAVVFAISVLVLGKGSPREEGLPSLAEMMPEEKVVLKTKHGQKAPENMSAFQIFCTYVLRNKNAWYVSFVDV
FVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKLFKGRRMPLAIICMTLIFICLIGYWKSE
SLLMVTVFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGASLGTSLFGVMVDKMGWHGGFYLLMGGIV
CCILFCYLSHRGALELEQQRKITEQEEARLALADAQ
>Mature_436_residues
MQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGISKGVMSSLADKASPKVFMACGLVLCAIV
NVGLGFSTAFWVFAALVVLNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNISHNVGGGIVAPIVGAAFAILGTEHWQS
ASYIVPACVAVVFAISVLVLGKGSPREEGLPSLAEMMPEEKVVLKTKHGQKAPENMSAFQIFCTYVLRNKNAWYVSFVDV
FVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKLFKGRRMPLAIICMTLIFICLIGYWKSE
SLLMVTVFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGASLGTSLFGVMVDKMGWHGGFYLLMGGIV
CCILFCYLSHRGALELEQQRKITEQEEARLALADAQ

Specific function: The phosphoglycerate transporter protein is a part of the PGT transport system. It is the membrane bound transporter for phosphoglycerate into salmonella [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=401, Percent_Identity=25.9351620947631, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4503847, Length=401, Percent_Identity=25.9351620947631, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI256219483, Length=401, Percent_Identity=25.9351620947631, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI256219543, Length=287, Percent_Identity=28.9198606271777, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38093649, Length=433, Percent_Identity=23.7875288683603, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI223717983, Length=433, Percent_Identity=23.7875288683603, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1788573, Length=430, Percent_Identity=36.7441860465116, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI2367259, Length=441, Percent_Identity=33.1065759637188, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI87082310, Length=417, Percent_Identity=31.89448441247, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI2367379, Length=311, Percent_Identity=23.7942122186495, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI2367193, Length=433, Percent_Identity=22.1709006928406, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17564202, Length=402, Percent_Identity=24.1293532338308, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564204, Length=397, Percent_Identity=24.1813602015113, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17542316, Length=424, Percent_Identity=20.9905660377358, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI133901854, Length=431, Percent_Identity=22.2737819025522, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI133901856, Length=431, Percent_Identity=22.2737819025522, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47858; Mature: 47858

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGISKGVMSSL
CHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ADKASPKVFMACGLVLCAIVNVGLGFSTAFWVFAALVVLNGLFQGMGVGPSFITIANWFP
HHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
RRERGRVGAFWNISHNVGGGIVAPIVGAAFAILGTEHWQSASYIVPACVAVVFAISVLVL
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GKGSPREEGLPSLAEMMPEEKVVLKTKHGQKAPENMSAFQIFCTYVLRNKNAWYVSFVDV
CCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEHHHHHH
FVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKLFKGRRMP
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LAIICMTLIFICLIGYWKSESLLMVTVFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GLRGFMSYIFGASLGTSLFGVMVDKMGWHGGFYLLMGGIVCCILFCYLSHRGALELEQQR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
KITEQEEARLALADAQ
CCCHHHHHHEEECCCC
>Mature Secondary Structure
MQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGISKGVMSSL
CHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ADKASPKVFMACGLVLCAIVNVGLGFSTAFWVFAALVVLNGLFQGMGVGPSFITIANWFP
HHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
RRERGRVGAFWNISHNVGGGIVAPIVGAAFAILGTEHWQSASYIVPACVAVVFAISVLVL
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
GKGSPREEGLPSLAEMMPEEKVVLKTKHGQKAPENMSAFQIFCTYVLRNKNAWYVSFVDV
CCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEHHHHHH
FVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKLFKGRRMP
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LAIICMTLIFICLIGYWKSESLLMVTVFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GLRGFMSYIFGASLGTSLFGVMVDKMGWHGGFYLLMGGIVCCILFCYLSHRGALELEQQR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
KITEQEEARLALADAQ
CCCHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 3042749 [H]