| Definition | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 chromosome, complete genome. |
|---|---|
| Accession | NC_009648 |
| Length | 5,315,120 |
Click here to switch to the map view.
The map label for this gene is pntB [H]
Identifier: 152970079
GI number: 152970079
Start: 1697556
End: 1698944
Strand: Direct
Name: pntB [H]
Synonym: KPN_01527
Alternate gene names: 152970079
Gene position: 1697556-1698944 (Clockwise)
Preceding gene: 152970078
Following gene: 152970080
Centisome position: 31.94
GC content: 58.53
Gene sequence:
>1389_bases ATGTCTGGTGGATTAGTAACGGCTGCATACATTGTTGCTGCAATCCTGTTTATTTTCAGCCTGGCGGGCCTGTCGAAACA CGAAACGTCGCAGCAGGGCAACTATTTCGGCATCGCCGGGATGGCCATTGCCCTGATTGCTACCATCCTGGGGCCGGACG CCGGCAACGTCGGCTGGATTATTCTTGCGATGGTGATCGGCGGGGCGATCGGTATTCGTCTGGCGAAGAAGGTCGAGATG ACCGAGATGCCGGAGCTGGTGGCTATCCTGCACAGCTTCGTGGGGCTGGCAGCGGTGCTGGTGGGTTTCAACAGCTACCT GCAGCATGAAACCGGTATGGAGCAAATTCTGGTCAATATTCATTTGACCGAAGTGTTCCTCGGGATCTTCATCGGCGCGG TGACCTTCACCGGTTCGGTGGTGGCGTTTGGTAAATTGCGCGGCAAAATTTCCTCCAGGCCGCTGATGCTGCCCAATCGC CATAAGCTGAACCTGGCGGCGCTGGTGGTTTCCTTCATCCTGATGGTGATTTTTGTTCGCTCTGACAGCACCGGCACCCA GGTCCTGTGCCTGCTGGTGATGACCGCGATCGCGCTGGCCTTTGGCTGGCACCTGGTGGCCTCTATCGGCGGTGCGGACA TGCCGGTGGTGGTCTCGATGCTCAACTCCTACTCGGGCTGGGCGGCAGCGGCGGCGGGCTTTATGCTGAGTAATGACCTG CTGATCGTCACCGGCGCGCTGGTGGGCTCTTCCGGCGCCATCCTCTCTTACATTATGTGTAAGGCGATGAACCGCTCCTT TATCAGCGTGATCGCCGGGGGCTTCGGCACCGATGGTTCCTCCAGCGGCGGCGATGAAGAAGTGGGCGAGCATCGCGAGA TTAGTGCCGAAGAGACGGCGGAGATGCTGAAAAACTCGCACTCGGTGATCATCACCCCGGGCTACGGTATGGCGGTGGCT CAGGCGCAGTATCCGGTAGCAGAAATTACCGAGAAGCTGCGGGCGCGGGGTATCAAAGTACGCTTTGGTATTCATCCGGT GGCCGGGCGCCTGCCGGGGCATATGAACGTCCTGCTGGCGGAAGCCAAAGTGCCTTACGACATCGTGCTGGAGATGGATG AGATCAACGACGATTTCAGCGACACCGACACCGTGCTGGTGATCGGCGCCAACGATACCGTCAACCCGGCGGCGCAGGAC GATCCGAAGAGCCCGATCGCCGGCATGCCGGTGCTCGAGGTGTGGAAAGCGCAGAATGTGGTGGTCTTTAAGCGTTCAAT GAACACCGGTTACGCCGGCGTACAGAACCCGCTGTTCTTTAAAGAGAACACTCATATGCTGTTTGGCGATGCTAAAGCCA GCGTCGATGCGATCCTGAAAGCGCTGTAA
Upstream 100 bases:
>100_bases AGCTTTATCGCGGTGCTGATCGCCAGCATTAATATTTTCGGTGGTTTTACCGTGACTCAGCGCATGCTGAAAATGTTTCG CAAAGGATAAGGGGTAGCAC
Downstream 100 bases:
>100_bases TGTAACATAATTGTTTTACAACGTTTGTTTATAAGCCGTCTCCTGTGAGACGGCTTTTTTATATGCAGGGAGATACCTGG AATTGTTCATAAAATAAGCG
Product: pyridine nucleotide transhydrogenase
Products: NA
Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Pyridine nucleotide transhydrogenase subunit beta [H]
Number of amino acids: Translated: 462; Mature: 461
Protein sequence:
>462_residues MSGGLVTAAYIVAAILFIFSLAGLSKHETSQQGNYFGIAGMAIALIATILGPDAGNVGWIILAMVIGGAIGIRLAKKVEM TEMPELVAILHSFVGLAAVLVGFNSYLQHETGMEQILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLRGKISSRPLMLPNR HKLNLAALVVSFILMVIFVRSDSTGTQVLCLLVMTAIALAFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSSGGDEEVGEHREISAEETAEMLKNSHSVIITPGYGMAVA QAQYPVAEITEKLRARGIKVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFSDTDTVLVIGANDTVNPAAQD DPKSPIAGMPVLEVWKAQNVVVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKAL
Sequences:
>Translated_462_residues MSGGLVTAAYIVAAILFIFSLAGLSKHETSQQGNYFGIAGMAIALIATILGPDAGNVGWIILAMVIGGAIGIRLAKKVEM TEMPELVAILHSFVGLAAVLVGFNSYLQHETGMEQILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLRGKISSRPLMLPNR HKLNLAALVVSFILMVIFVRSDSTGTQVLCLLVMTAIALAFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSSGGDEEVGEHREISAEETAEMLKNSHSVIITPGYGMAVA QAQYPVAEITEKLRARGIKVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFSDTDTVLVIGANDTVNPAAQD DPKSPIAGMPVLEVWKAQNVVVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKAL >Mature_461_residues SGGLVTAAYIVAAILFIFSLAGLSKHETSQQGNYFGIAGMAIALIATILGPDAGNVGWIILAMVIGGAIGIRLAKKVEMT EMPELVAILHSFVGLAAVLVGFNSYLQHETGMEQILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLRGKISSRPLMLPNRH KLNLAALVVSFILMVIFVRSDSTGTQVLCLLVMTAIALAFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLL IVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSSGGDEEVGEHREISAEETAEMLKNSHSVIITPGYGMAVAQ AQYPVAEITEKLRARGIKVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFSDTDTVLVIGANDTVNPAAQDD PKSPIAGMPVLEVWKAQNVVVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKAL
Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]
COG id: COG1282
COG function: function code C; NAD/NADP transhydrogenase beta subunit
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the PNT beta subunit family [H]
Homologues:
Organism=Homo sapiens, GI122939155, Length=453, Percent_Identity=52.317880794702, Blast_Score=468, Evalue=1e-132, Organism=Homo sapiens, GI122939153, Length=453, Percent_Identity=52.317880794702, Blast_Score=468, Evalue=1e-132, Organism=Escherichia coli, GI1787886, Length=462, Percent_Identity=93.2900432900433, Blast_Score=878, Evalue=0.0, Organism=Caenorhabditis elegans, GI17550456, Length=457, Percent_Identity=49.671772428884, Blast_Score=431, Evalue=1e-121,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012136 - InterPro: IPR004003 [H]
Pfam domain/function: PF02233 PNTB [H]
EC number: =1.6.1.2 [H]
Molecular weight: Translated: 48801; Mature: 48669
Theoretical pI: Translated: 5.95; Mature: 5.95
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 4.5 %Met (Translated Protein) 5.0 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 4.3 %Met (Mature Protein) 4.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSGGLVTAAYIVAAILFIFSLAGLSKHETSQQGNYFGIAGMAIALIATILGPDAGNVGWI CCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCCHHHH ILAMVIGGAIGIRLAKKVEMTEMPELVAILHSFVGLAAVLVGFNSYLQHETGMEQILVNI HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH HLTEVFLGIFIGAVTFTGSVVAFGKLRGKISSRPLMLPNRHKLNLAALVVSFILMVIFVR HHHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC SDSTGTQVLCLLVMTAIALAFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCE LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSSGGDEEVGEHREISAEETA EEEEEEHHCCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCHHHHH EMLKNSHSVIITPGYGMAVAQAQYPVAEITEKLRARGIKVRFGIHPVAGRLPGHMNVLLA HHHHCCCCEEEECCCCCEEHHCCCCHHHHHHHHHHCCEEEEECCCHHCCCCCCCCEEEEE EAKVPYDIVLEMDEINDDFSDTDTVLVIGANDTVNPAAQDDPKSPIAGMPVLEVWKAQNV CCCCCEEEEEEEHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCE VVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKAL EEEEECCCCCCCCCCCCEEEECCCEEEEECCHHHHHHHHHCC >Mature Secondary Structure SGGLVTAAYIVAAILFIFSLAGLSKHETSQQGNYFGIAGMAIALIATILGPDAGNVGWI CCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCCHHHH ILAMVIGGAIGIRLAKKVEMTEMPELVAILHSFVGLAAVLVGFNSYLQHETGMEQILVNI HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH HLTEVFLGIFIGAVTFTGSVVAFGKLRGKISSRPLMLPNRHKLNLAALVVSFILMVIFVR HHHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC SDSTGTQVLCLLVMTAIALAFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCE LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSSGGDEEVGEHREISAEETA EEEEEEHHCCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCHHHHH EMLKNSHSVIITPGYGMAVAQAQYPVAEITEKLRARGIKVRFGIHPVAGRLPGHMNVLLA HHHHCCCCEEEECCCCCEEHHCCCCHHHHHHHHHHCCEEEEECCCHHCCCCCCCCEEEEE EAKVPYDIVLEMDEINDDFSDTDTVLVIGANDTVNPAAQDDPKSPIAGMPVLEVWKAQNV CCCCCEEEEEEEHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCCCE VVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKAL EEEEECCCCCCCCCCCCEEEECCCEEEEECCHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]