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The map label for this gene is yccK [H]

Identifier: 152970044

GI number: 152970044

Start: 1656315

End: 1657253

Strand: Direct

Name: yccK [H]

Synonym: KPN_01491

Alternate gene names: 152970044

Gene position: 1656315-1657253 (Clockwise)

Preceding gene: 152970037

Following gene: 152970046

Centisome position: 31.16

GC content: 57.29

Gene sequence:

>939_bases
ATGGGGATGAGTTTTGCCTATGGCGGCGCTGAAACGTCGCAGGCGATAAATACGATCCATGCCGCCATGGACATGGGCGT
GACCTTCCTGGATACCGCCGAAGTATATGGTCCTTTCGATAATGAAGTTCTGGTCGGAAAAGCGATTAAAGGTTTTCGCG
ATAAGGTGCAGATTGCCACCAAATTTGGATTTCGTATTTTGCCGACCGGCCAGGGTCTGGAGCGGATGGCCGGCGTTGAC
AGCCGTCCGGCACATATTCGCGAATCAGTGGAAGGGTCGCTGAAGCGACTGAATGTCGAGACCATCGATCTGCTCTATCA
GCACCGCGTCGATCCCGCGGTACCGGTGGAAGAGGTGGTGGGCACTATGGCCGATCTGGTTAAAGAGGGTAAAATTCGCC
ATATCGGTCTGTCGGAAGTATCTGCTCAGACGCTGCGCCGGGCCTGCAAGGTACATCCGATCGCTGCCGTGCAGACGGAA
TATTCGCTATGGAGCCGCGAGCCGGAGGCCGGTATTCTCCACTCCTGCCGCGAGCTGGGGGTCGGCTTTGTGCCATACAG
CCCGCTTGGCCGCGGCTTCCTGACGGGGACAATTACCGATCCCGGCGTTTTGGCAGCGGATGATTTCCGCCGCCATCTGC
CGCGCTTCCAGGCCGAAACCATGCGCAAAAACCAGCTGCTGCTTGAGCGCCTGCAGCAGGTGGCCACCCGCTATGACGCG
ACCCTTGCGCAGATTGCCCTTGCCTGGGTGATGAGCAAAGGCGAGGATATCGTGCCTATCCCGGGGGCGAGGAAAATTGC
TCACCTGCGCGACAATGCCGGCGCCGCGAATATTACTCTCGCGCCGGAGGACATCCTCACCATCGAACATATTTTCACTG
CCGACAACGTCACTGGCTTACGCTATACCCAGGGCGACTTTGATTTAATCGAAAAATAA

Upstream 100 bases:

>100_bases
AGTATATATTTAATGCCATTCAGCAATTAAGGAAAATAAGATGAAAACACGTTATCTTGGAAAAGAGAAGTTTCAGGTTT
CCGCATTAGGTCTCGGATGT

Downstream 100 bases:

>100_bases
TCCCCTACGGGCAGCGGATGGTTATTACTTGCGTGACGTTGTCACCTTTGCTTAACAACTCCTCGTCAGATAGCGCACAT
CCTCGGCGGTTAACGGCGCG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MGMSFAYGGAETSQAINTIHAAMDMGVTFLDTAEVYGPFDNEVLVGKAIKGFRDKVQIATKFGFRILPTGQGLERMAGVD
SRPAHIRESVEGSLKRLNVETIDLLYQHRVDPAVPVEEVVGTMADLVKEGKIRHIGLSEVSAQTLRRACKVHPIAAVQTE
YSLWSREPEAGILHSCRELGVGFVPYSPLGRGFLTGTITDPGVLAADDFRRHLPRFQAETMRKNQLLLERLQQVATRYDA
TLAQIALAWVMSKGEDIVPIPGARKIAHLRDNAGAANITLAPEDILTIEHIFTADNVTGLRYTQGDFDLIEK

Sequences:

>Translated_312_residues
MGMSFAYGGAETSQAINTIHAAMDMGVTFLDTAEVYGPFDNEVLVGKAIKGFRDKVQIATKFGFRILPTGQGLERMAGVD
SRPAHIRESVEGSLKRLNVETIDLLYQHRVDPAVPVEEVVGTMADLVKEGKIRHIGLSEVSAQTLRRACKVHPIAAVQTE
YSLWSREPEAGILHSCRELGVGFVPYSPLGRGFLTGTITDPGVLAADDFRRHLPRFQAETMRKNQLLLERLQQVATRYDA
TLAQIALAWVMSKGEDIVPIPGARKIAHLRDNAGAANITLAPEDILTIEHIFTADNVTGLRYTQGDFDLIEK
>Mature_311_residues
GMSFAYGGAETSQAINTIHAAMDMGVTFLDTAEVYGPFDNEVLVGKAIKGFRDKVQIATKFGFRILPTGQGLERMAGVDS
RPAHIRESVEGSLKRLNVETIDLLYQHRVDPAVPVEEVVGTMADLVKEGKIRHIGLSEVSAQTLRRACKVHPIAAVQTEY
SLWSREPEAGILHSCRELGVGFVPYSPLGRGFLTGTITDPGVLAADDFRRHLPRFQAETMRKNQLLLERLQQVATRYDAT
LAQIALAWVMSKGEDIVPIPGARKIAHLRDNAGAANITLAPEDILTIEHIFTADNVTGLRYTQGDFDLIEK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=325, Percent_Identity=29.8461538461538, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI4504825, Length=325, Percent_Identity=29.8461538461538, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI27436964, Length=325, Percent_Identity=29.2307692307692, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI27436962, Length=325, Percent_Identity=29.2307692307692, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI27436966, Length=327, Percent_Identity=29.6636085626911, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI27436971, Length=298, Percent_Identity=28.5234899328859, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI223718702, Length=297, Percent_Identity=28.956228956229, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI41327764, Length=183, Percent_Identity=30.0546448087432, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI41152114, Length=196, Percent_Identity=30.1020408163265, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87081735, Length=302, Percent_Identity=34.1059602649007, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1788070, Length=278, Percent_Identity=34.8920863309352, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1789375, Length=307, Percent_Identity=28.9902280130293, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787674, Length=284, Percent_Identity=28.169014084507, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788081, Length=300, Percent_Identity=26.3333333333333, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789199, Length=323, Percent_Identity=27.2445820433437, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI48994888, Length=283, Percent_Identity=27.9151943462898, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564128, Length=305, Percent_Identity=25.9016393442623, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319958, Length=301, Percent_Identity=28.5714285714286, Blast_Score=112, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6323998, Length=303, Percent_Identity=29.3729372937294, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6325384, Length=322, Percent_Identity=28.2608695652174, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6322615, Length=259, Percent_Identity=29.3436293436293, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6325169, Length=310, Percent_Identity=26.1290322580645, Blast_Score=93, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6319951, Length=296, Percent_Identity=25.3378378378378, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24644950, Length=291, Percent_Identity=23.3676975945017, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646155, Length=143, Percent_Identity=33.5664335664336, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34263; Mature: 34132

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMSFAYGGAETSQAINTIHAAMDMGVTFLDTAEVYGPFDNEVLVGKAIKGFRDKVQIAT
CCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCEEEHHHHHHHHHHHHHHH
KFGFRILPTGQGLERMAGVDSRPAHIRESVEGSLKRLNVETIDLLYQHRVDPAVPVEEVV
HCCCEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHH
GTMADLVKEGKIRHIGLSEVSAQTLRRACKVHPIAAVQTEYSLWSREPEAGILHSCRELG
HHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCC
VGFVPYSPLGRGFLTGTITDPGVLAADDFRRHLPRFQAETMRKNQLLLERLQQVATRYDA
CCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLAQIALAWVMSKGEDIVPIPGARKIAHLRDNAGAANITLAPEDILTIEHIFTADNVTGL
HHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCCCCCEEEECCHHHHHHHHHEECCCCCCC
RYTQGDFDLIEK
EEECCCHHHHCC
>Mature Secondary Structure 
GMSFAYGGAETSQAINTIHAAMDMGVTFLDTAEVYGPFDNEVLVGKAIKGFRDKVQIAT
CCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCEEEHHHHHHHHHHHHHHH
KFGFRILPTGQGLERMAGVDSRPAHIRESVEGSLKRLNVETIDLLYQHRVDPAVPVEEVV
HCCCEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHH
GTMADLVKEGKIRHIGLSEVSAQTLRRACKVHPIAAVQTEYSLWSREPEAGILHSCRELG
HHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCC
VGFVPYSPLGRGFLTGTITDPGVLAADDFRRHLPRFQAETMRKNQLLLERLQQVATRYDA
CCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLAQIALAWVMSKGEDIVPIPGARKIAHLRDNAGAANITLAPEDILTIEHIFTADNVTGL
HHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCCCCCEEEECCHHHHHHHHHEECCCCCCC
RYTQGDFDLIEK
EEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]