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The map label for this gene is argE [H]

Identifier: 152970017

GI number: 152970017

Start: 1625368

End: 1626525

Strand: Direct

Name: argE [H]

Synonym: KPN_01464

Alternate gene names: 152970017

Gene position: 1625368-1626525 (Clockwise)

Preceding gene: 152970016

Following gene: 152970018

Centisome position: 30.58

GC content: 65.98

Gene sequence:

>1158_bases
ATGAATAACATCCTCGCCGCGCTGCTGGCTTTTGACACCACCAGCCGCCATTCGAACCTGGCGATGATCAACTGGATCGC
CGATTTTCTCGCTGCCCGCGGCGTGGCGTCCCGCCGCTTTTATGACCCGTCGGGCGGTAAGGCCAATCTCTACGCCCGGC
TGGGGCCGTCCGGCGGCGGTGGGGTGATGCTCTCGGGCCACACCGACGTGGTCCCGGTGGACGGCCAGGCCTGGAGCGTT
CCGCCTTTCAGCCTGACCGAGCGCGATGGCCGCTACTATGGCCGCGGCAGCGCCGATATGAAGGGGTTTCTCGCCTGCGT
GCTGGCGGCAGTGGATGACTTTCTGGCGGCGCCGCTGCGCATGCCACTGCATCTGGCCTTCTCCTATGACGAAGAGGTCG
GCTGTCTCGGTGTGCGCAGCCTGGTGGATTTTCTGCAGGCCTCGCCGGAGAAACCGGCGCTGTGCCTCATCGGCGAGCCG
ACAGAGATGCAGCCGGTGTTCGGTCATAAAGGCAAACTGGCCATGCGCTGCTGCATCGAGGGGCAGGCCTGCCATTCGGC
CTATGCCCCGCAGGGGGTGAACGCCATCCGCTACGCGGCCAGGCTGATCAACCATTTGGATCGGCTGGGCGTGCGTCTGG
CCCGGCAGCAGGACAGCCGCTTTTCGCCGCCCTTCAGCACGCTGCAGGTGGGCACCATTCAGGGTGGGGCCGCGCTGAAT
ATTGTTCCGCAGTCCTGCCGCTTTGATTTTGAGATCCGCTACCTGCCGGGGATGCGTCCCGAAGCGGTCACCGAGGCGCT
GGCGGCCTACGCCCGTCGCCAGCTGCTGCCGGAGATGCGCCGGGTAGGCAGCGGGAGCGACATCCAGTTCCAGCTGTTAA
GCCACTATCCGCCGCTGCTCAGCGATCCGCAGTCCGACTTCGCCCGCTGGCTGGCGCAGTGGTGCGGCAGCGACCGCTTC
TCCACCGTGGCGTTCGGCACCGAAGGAGGGCTGTTCGATGAGATGGGCGTCGCGACCCTGGTCTGCGGACCGGGCAGCAT
GGCCCAGGGCCATAAGGCCGATGAGTACATCAGCATCGCGCAGACCGAGCGCTGTATGACGATGCTGCGACAGCTTTGCG
CGTGGATGCGTGCCGAACCGGCGGAACCGCTCACCTGA

Upstream 100 bases:

>100_bases
GCCCTTGAGCAGCTGTGGCTGGCCTGGGAGCCGCAAATGGACGCCTATATTACCCGGGCGCTCGACCCGCGCGAGGCGCC
CGCCTATGGCGTCCCCGGCG

Downstream 100 bases:

>100_bases
TCCCTCAACACAGGAACCCAAGCGATGCACAATCAACACTCTCCCCACATCGATCAAGCGACCATCGACCGCTGGCAGGC
GGATGGCGCGGTGTTATTAA

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNNILAALLAFDTTSRHSNLAMINWIADFLAARGVASRRFYDPSGGKANLYARLGPSGGGGVMLSGHTDVVPVDGQAWSV
PPFSLTERDGRYYGRGSADMKGFLACVLAAVDDFLAAPLRMPLHLAFSYDEEVGCLGVRSLVDFLQASPEKPALCLIGEP
TEMQPVFGHKGKLAMRCCIEGQACHSAYAPQGVNAIRYAARLINHLDRLGVRLARQQDSRFSPPFSTLQVGTIQGGAALN
IVPQSCRFDFEIRYLPGMRPEAVTEALAAYARRQLLPEMRRVGSGSDIQFQLLSHYPPLLSDPQSDFARWLAQWCGSDRF
STVAFGTEGGLFDEMGVATLVCGPGSMAQGHKADEYISIAQTERCMTMLRQLCAWMRAEPAEPLT

Sequences:

>Translated_385_residues
MNNILAALLAFDTTSRHSNLAMINWIADFLAARGVASRRFYDPSGGKANLYARLGPSGGGGVMLSGHTDVVPVDGQAWSV
PPFSLTERDGRYYGRGSADMKGFLACVLAAVDDFLAAPLRMPLHLAFSYDEEVGCLGVRSLVDFLQASPEKPALCLIGEP
TEMQPVFGHKGKLAMRCCIEGQACHSAYAPQGVNAIRYAARLINHLDRLGVRLARQQDSRFSPPFSTLQVGTIQGGAALN
IVPQSCRFDFEIRYLPGMRPEAVTEALAAYARRQLLPEMRRVGSGSDIQFQLLSHYPPLLSDPQSDFARWLAQWCGSDRF
STVAFGTEGGLFDEMGVATLVCGPGSMAQGHKADEYISIAQTERCMTMLRQLCAWMRAEPAEPLT
>Mature_385_residues
MNNILAALLAFDTTSRHSNLAMINWIADFLAARGVASRRFYDPSGGKANLYARLGPSGGGGVMLSGHTDVVPVDGQAWSV
PPFSLTERDGRYYGRGSADMKGFLACVLAAVDDFLAAPLRMPLHLAFSYDEEVGCLGVRSLVDFLQASPEKPALCLIGEP
TEMQPVFGHKGKLAMRCCIEGQACHSAYAPQGVNAIRYAARLINHLDRLGVRLARQQDSRFSPPFSTLQVGTIQGGAALN
IVPQSCRFDFEIRYLPGMRPEAVTEALAAYARRQLLPEMRRVGSGSDIQFQLLSHYPPLLSDPQSDFARWLAQWCGSDRF
STVAFGTEGGLFDEMGVATLVCGPGSMAQGHKADEYISIAQTERCMTMLRQLCAWMRAEPAEPLT

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=363, Percent_Identity=34.1597796143251, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1788816, Length=335, Percent_Identity=28.6567164179104, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17551016, Length=367, Percent_Identity=25.0681198910082, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 41932; Mature: 41932

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNILAALLAFDTTSRHSNLAMINWIADFLAARGVASRRFYDPSGGKANLYARLGPSGGG
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCEEEEEEECCCCCC
GVMLSGHTDVVPVDGQAWSVPPFSLTERDGRYYGRGSADMKGFLACVLAAVDDFLAAPLR
CEEECCCCCEEECCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHC
MPLHLAFSYDEEVGCLGVRSLVDFLQASPEKPALCLIGEPTEMQPVFGHKGKLAMRCCIE
CCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECC
GQACHSAYAPQGVNAIRYAARLINHLDRLGVRLARQQDSRFSPPFSTLQVGTIQGGAALN
CHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCCEEEE
IVPQSCRFDFEIRYLPGMRPEAVTEALAAYARRQLLPEMRRVGSGSDIQFQLLSHYPPLL
EECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCC
SDPQSDFARWLAQWCGSDRFSTVAFGTEGGLFDEMGVATLVCGPGSMAQGHKADEYISIA
CCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHCCCEEEEECCCCCCCCCCCHHHHHHH
QTERCMTMLRQLCAWMRAEPAEPLT
HHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNNILAALLAFDTTSRHSNLAMINWIADFLAARGVASRRFYDPSGGKANLYARLGPSGGG
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCEEEEEEECCCCCC
GVMLSGHTDVVPVDGQAWSVPPFSLTERDGRYYGRGSADMKGFLACVLAAVDDFLAAPLR
CEEECCCCCEEECCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHC
MPLHLAFSYDEEVGCLGVRSLVDFLQASPEKPALCLIGEPTEMQPVFGHKGKLAMRCCIE
CCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCEEEEEECC
GQACHSAYAPQGVNAIRYAARLINHLDRLGVRLARQQDSRFSPPFSTLQVGTIQGGAALN
CHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCCEEEE
IVPQSCRFDFEIRYLPGMRPEAVTEALAAYARRQLLPEMRRVGSGSDIQFQLLSHYPPLL
EECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHCCCCCC
SDPQSDFARWLAQWCGSDRFSTVAFGTEGGLFDEMGVATLVCGPGSMAQGHKADEYISIA
CCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHCCCEEEEECCCCCCCCCCCHHHHHHH
QTERCMTMLRQLCAWMRAEPAEPLT
HHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9829957 [H]