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The map label for this gene is yvbU [H]

Identifier: 152970014

GI number: 152970014

Start: 1621902

End: 1622816

Strand: Direct

Name: yvbU [H]

Synonym: KPN_01461

Alternate gene names: 152970014

Gene position: 1621902-1622816 (Clockwise)

Preceding gene: 152970009

Following gene: 152970015

Centisome position: 30.51

GC content: 56.39

Gene sequence:

>915_bases
ATGAACCGATTTACCCTGAAGCAGCTCAAATATTTCGTCACCGTGGTGGAGACGGAGAGTATCGCCGAGGCCTCCCGCCA
GCTGCACATTGCGCAGCCGTCGATTTCGATTGCCATCAAGAATCTGGAGAGCACCTTCGACCAGCAGCTGTTTATTCGCC
ACCATGCGCAGGGCGTTTCGCTCACCTCCAGCGGTCGGCGGATCTACGATAAAGCGAAAGAGCTGCTGCGCCTGTCCTGG
GAGTTCGAACAGAATTCGCGAGCGGATAAAGAGCTGGTTTCTGGCATGATCTCCATCGGTTGCTTCGAATCGGTGGCTCC
GCTGTATATGCCGAAGCTGGTGGCCGGGTTTAAGAAATGCTATCCGGAAATCACCCTGCATCTGTACGACGGCGAACAGC
ATGAGCTGATGCATGGCCTGCACCGCGGCCGCTTCGACCTGGCGCTGGTTTACGATCTGGAGCTCGGCCATTCGATCAAT
AAAGAGCGGCTCAATGCCCCGCATAAACCCTACGCGCTGCTGCCCGCCGCGCATCCGCTGGCGCAGAAGGCGCAGGTGAC
GCTGCAGGAGCTGAGCCGCGAGCCGATGATCCTCCTCGATGCGGTCCCCAGTAAAAATTATTTTATCTCCATCTTTAAGG
AAAAGGGTTATCACCCGGAAGTGGCTTACAGTTCCCCCTCCATTGAAATGGTGCGCTGTATGGTGGGTCAGGGGTTGGGT
TTTTCGGTGCTGGTCACCCGGCCCTGCTGCGATATGACCTACGATGGCGAAAGAGTGGTGCAGCGGGATATTGCCGACGA
GATGCCCGCCTCGACCTTAATTATGGCGCATCTCGCGAATAATGAGCCCACGCGGCCGACGCAACTGTTTATGGATTATT
GTCGCAGCATCGAATTAACCCCAACTCACGCCTGA

Upstream 100 bases:

>100_bases
GTGCGCCGCTCTTTTCCGGGGGTGGCACGCGGATTGCTTGGGACTTAGAGGAAAACTATTCCCTGTGTGCGCCGGACCAT
ATTTTATCAATGGTGATGCT

Downstream 100 bases:

>100_bases
AATAACGCCTGTCGATCCGGCAGGCGTTATTTTTTTGTCGTCACTCAGCCTCGTAAAATTCTATTCAGTCGATCGTTTTA
TAATATTTTACCAATTCGTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNRFTLKQLKYFVTVVETESIAEASRQLHIAQPSISIAIKNLESTFDQQLFIRHHAQGVSLTSSGRRIYDKAKELLRLSW
EFEQNSRADKELVSGMISIGCFESVAPLYMPKLVAGFKKCYPEITLHLYDGEQHELMHGLHRGRFDLALVYDLELGHSIN
KERLNAPHKPYALLPAAHPLAQKAQVTLQELSREPMILLDAVPSKNYFISIFKEKGYHPEVAYSSPSIEMVRCMVGQGLG
FSVLVTRPCCDMTYDGERVVQRDIADEMPASTLIMAHLANNEPTRPTQLFMDYCRSIELTPTHA

Sequences:

>Translated_304_residues
MNRFTLKQLKYFVTVVETESIAEASRQLHIAQPSISIAIKNLESTFDQQLFIRHHAQGVSLTSSGRRIYDKAKELLRLSW
EFEQNSRADKELVSGMISIGCFESVAPLYMPKLVAGFKKCYPEITLHLYDGEQHELMHGLHRGRFDLALVYDLELGHSIN
KERLNAPHKPYALLPAAHPLAQKAQVTLQELSREPMILLDAVPSKNYFISIFKEKGYHPEVAYSSPSIEMVRCMVGQGLG
FSVLVTRPCCDMTYDGERVVQRDIADEMPASTLIMAHLANNEPTRPTQLFMDYCRSIELTPTHA
>Mature_304_residues
MNRFTLKQLKYFVTVVETESIAEASRQLHIAQPSISIAIKNLESTFDQQLFIRHHAQGVSLTSSGRRIYDKAKELLRLSW
EFEQNSRADKELVSGMISIGCFESVAPLYMPKLVAGFKKCYPEITLHLYDGEQHELMHGLHRGRFDLALVYDLELGHSIN
KERLNAPHKPYALLPAAHPLAQKAQVTLQELSREPMILLDAVPSKNYFISIFKEKGYHPEVAYSSPSIEMVRCMVGQGLG
FSVLVTRPCCDMTYDGERVVQRDIADEMPASTLIMAHLANNEPTRPTQLFMDYCRSIELTPTHA

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=248, Percent_Identity=24.5967741935484, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787879, Length=245, Percent_Identity=27.7551020408163, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787530, Length=252, Percent_Identity=23.4126984126984, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788887, Length=282, Percent_Identity=25.886524822695, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788297, Length=151, Percent_Identity=31.7880794701987, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI145693105, Length=241, Percent_Identity=26.5560165975104, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787601, Length=161, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI157672245, Length=230, Percent_Identity=30, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788296, Length=243, Percent_Identity=23.4567901234568, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789204, Length=274, Percent_Identity=24.8175182481752, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI2367136, Length=279, Percent_Identity=25.089605734767, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788748, Length=254, Percent_Identity=25.9842519685039, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787806, Length=153, Percent_Identity=27.4509803921569, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34481; Mature: 34481

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS50931 HTH_LYSR ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFTLKQLKYFVTVVETESIAEASRQLHIAQPSISIAIKNLESTFDQQLFIRHHAQGVS
CCCHHHHHHHHHHHHCCHHHHHHHHHEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCE
LTSSGRRIYDKAKELLRLSWEFEQNSRADKELVSGMISIGCFESVAPLYMPKLVAGFKKC
ECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YPEITLHLYDGEQHELMHGLHRGRFDLALVYDLELGHSINKERLNAPHKPYALLPAAHPL
CCEEEEEEECCCHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHCCCCCCCEEECCCCCCH
AQKAQVTLQELSREPMILLDAVPSKNYFISIFKEKGYHPEVAYSSPSIEMVRCMVGQGLG
HHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCCCCEEECCCCHHHHHHHHCCCCC
FSVLVTRPCCDMTYDGERVVQRDIADEMPASTLIMAHLANNEPTRPTQLFMDYCRSIELT
EEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHHEECCCCCCCCHHHHHHHHHHCCCCC
PTHA
CCCC
>Mature Secondary Structure
MNRFTLKQLKYFVTVVETESIAEASRQLHIAQPSISIAIKNLESTFDQQLFIRHHAQGVS
CCCHHHHHHHHHHHHCCHHHHHHHHHEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCE
LTSSGRRIYDKAKELLRLSWEFEQNSRADKELVSGMISIGCFESVAPLYMPKLVAGFKKC
ECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YPEITLHLYDGEQHELMHGLHRGRFDLALVYDLELGHSINKERLNAPHKPYALLPAAHPL
CCEEEEEEECCCHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHCCCCCCCEEECCCCCCH
AQKAQVTLQELSREPMILLDAVPSKNYFISIFKEKGYHPEVAYSSPSIEMVRCMVGQGLG
HHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCCCCEEECCCCHHHHHHHHCCCCC
FSVLVTRPCCDMTYDGERVVQRDIADEMPASTLIMAHLANNEPTRPTQLFMDYCRSIELT
EEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHHEECCCCCCCCHHHHHHHHHHCCCCC
PTHA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]