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The map label for this gene is opdE [H]

Identifier: 152969867

GI number: 152969867

Start: 1475446

End: 1476648

Strand: Direct

Name: opdE [H]

Synonym: KPN_01314

Alternate gene names: 152969867

Gene position: 1475446-1476648 (Clockwise)

Preceding gene: 152969865

Following gene: 152969868

Centisome position: 27.76

GC content: 59.19

Gene sequence:

>1203_bases
ATGTCTGCATTAGGTCACACCCGGGCACACTGGAGCGGCGTCCTGGCGATGACGCTCTGCGTATTTGTGCTCATTGCCTC
AGAATTTATGCCGGTCAGTCTGTTGACACCCATCGCGGGTGATTTACACATTACCAAGGGATTAGCCGGTCAGGGCATTG
CGCTTTCTGGCGCGCTGGCGGTACTGACCAGCCTGACGATATCCCGTCTTACCGGATCGCTGGACCGTAAATGGCTGCTG
CTGGGGCTCACGGCGTTGATGGCAGCCTCTGGGGTGATTATTGCCCTGGCGTCCAGTTTCCCGGTTTATATGCTGGGCAG
AGCGCTCATTGGGATCGTCATCGGCGGCTTCTGGTCGATGTCGGCGGCAACGGCCATTCGGCTGGTGCCGCAACGCCAGG
TCCCCCGCACACTGGCCATCTTTAACGGCGGCAACGCGCTGGCCACCGTTGTGGCAGCGCCGCTGGGCAGCTACCTGGGG
GCCACCGTCGGCTGGTGCGGCGCCTTTTTATGTCTTGTCCCGCTGGCGGTGCTGGCCTTCGTCTGGCAATGCATTAGCCT
GCCGTCGATGAAAAGTCCGCGCGCACCACAGCGGCAGGGATCGGTGCTGCGTCTGTTCCGTCTTTCTACGCTATCCCTGG
GATTGCTGGCCTGCGGACTGTTCTTTATGGGACAGTTTACCTTATTTACCTATGTGCGACCGTTTCTGGAGACGGTGACC
CAAGTCAGTCCTTCTGGTCTGTCCCTGATATTGCTGACAATGGGTATCGCCGGTTTTATCGGCACGCTGCTTATTACGAC
CGTTCTGAATGCCCGATTTTATCCGACGCTGGTGGCTATCCCGTTGTTAATGGCCGCAATTGCCGGAACGCTTCTGCTGG
CCGGACACCACACGGGATCGGTCGCCGTACTGTTAAGCCTGTGGGGGCTGCTGGCGACGGCGGCGCCCACCGGCTGGTGG
ACATGGATTGCGCGGACGCTGCCCGAGGATGCGGAGACGGGCGGCGGGCTGATGGTCGCCGTGATCCAGCTATCGATATC
CCTCGGGTCAACGGTAGGCGGCCTGGTGTTTGATAGTCTGGGATGGCACAGCACTTTTGCACTGAGCGGTCTGTTACTGC
TGGGCGCGGCAGGGGTGACTTTTCTGCTCTCTGTCAAAATCAGATCATCTCAGCGCACTGCGATTAATGAATTGAATGCA
TAA

Upstream 100 bases:

>100_bases
GCAATTTTTTAAAACCAACCTGAAATAGATCTCCTGTGCCGGAGACATCCCCAAAGCCGCCACGCGCCTGCGGGCGGCTT
TGTCTTGTCGGAGAGAAATA

Downstream 100 bases:

>100_bases
GTCAAATCAGGAATGACAGGCTAATCGTGACCGCGTTCCTGTCTTACCATGGTGTTTTAACAAGAGGGGAGCTTCACCGT
GGAATATTCAATATTAAGTA

Product: MFS family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSALGHTRAHWSGVLAMTLCVFVLIASEFMPVSLLTPIAGDLHITKGLAGQGIALSGALAVLTSLTISRLTGSLDRKWLL
LGLTALMAASGVIIALASSFPVYMLGRALIGIVIGGFWSMSAATAIRLVPQRQVPRTLAIFNGGNALATVVAAPLGSYLG
ATVGWCGAFLCLVPLAVLAFVWQCISLPSMKSPRAPQRQGSVLRLFRLSTLSLGLLACGLFFMGQFTLFTYVRPFLETVT
QVSPSGLSLILLTMGIAGFIGTLLITTVLNARFYPTLVAIPLLMAAIAGTLLLAGHHTGSVAVLLSLWGLLATAAPTGWW
TWIARTLPEDAETGGGLMVAVIQLSISLGSTVGGLVFDSLGWHSTFALSGLLLLGAAGVTFLLSVKIRSSQRTAINELNA

Sequences:

>Translated_400_residues
MSALGHTRAHWSGVLAMTLCVFVLIASEFMPVSLLTPIAGDLHITKGLAGQGIALSGALAVLTSLTISRLTGSLDRKWLL
LGLTALMAASGVIIALASSFPVYMLGRALIGIVIGGFWSMSAATAIRLVPQRQVPRTLAIFNGGNALATVVAAPLGSYLG
ATVGWCGAFLCLVPLAVLAFVWQCISLPSMKSPRAPQRQGSVLRLFRLSTLSLGLLACGLFFMGQFTLFTYVRPFLETVT
QVSPSGLSLILLTMGIAGFIGTLLITTVLNARFYPTLVAIPLLMAAIAGTLLLAGHHTGSVAVLLSLWGLLATAAPTGWW
TWIARTLPEDAETGGGLMVAVIQLSISLGSTVGGLVFDSLGWHSTFALSGLLLLGAAGVTFLLSVKIRSSQRTAINELNA
>Mature_399_residues
SALGHTRAHWSGVLAMTLCVFVLIASEFMPVSLLTPIAGDLHITKGLAGQGIALSGALAVLTSLTISRLTGSLDRKWLLL
GLTALMAASGVIIALASSFPVYMLGRALIGIVIGGFWSMSAATAIRLVPQRQVPRTLAIFNGGNALATVVAAPLGSYLGA
TVGWCGAFLCLVPLAVLAFVWQCISLPSMKSPRAPQRQGSVLRLFRLSTLSLGLLACGLFFMGQFTLFTYVRPFLETVTQ
VSPSGLSLILLTMGIAGFIGTLLITTVLNARFYPTLVAIPLLMAAIAGTLLLAGHHTGSVAVLLSLWGLLATAAPTGWWT
WIARTLPEDAETGGGLMVAVIQLSISLGSTVGGLVFDSLGWHSTFALSGLLLLGAAGVTFLLSVKIRSSQRTAINELNA

Specific function: Regulates the expression of oprD which encodes the imipenem-specific porin [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ywfA [H]

Homologues:

Organism=Escherichia coli, GI145693198, Length=385, Percent_Identity=38.4415584415584, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI1787808, Length=238, Percent_Identity=26.890756302521, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787947, Length=295, Percent_Identity=26.4406779661017, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786595, Length=353, Percent_Identity=24.6458923512748, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41713; Mature: 41582

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALGHTRAHWSGVLAMTLCVFVLIASEFMPVSLLTPIAGDLHITKGLAGQGIALSGALA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEECCCCCCCCHHHHHHH
VLTSLTISRLTGSLDRKWLLLGLTALMAASGVIIALASSFPVYMLGRALIGIVIGGFWSM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHHHHHHHHHHH
SAATAIRLVPQRQVPRTLAIFNGGNALATVVAAPLGSYLGATVGWCGAFLCLVPLAVLAF
HHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWQCISLPSMKSPRAPQRQGSVLRLFRLSTLSLGLLACGLFFMGQFTLFTYVRPFLETVT
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVSPSGLSLILLTMGIAGFIGTLLITTVLNARFYPTLVAIPLLMAAIAGTLLLAGHHTGS
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
VAVLLSLWGLLATAAPTGWWTWIARTLPEDAETGGGLMVAVIQLSISLGSTVGGLVFDSL
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCC
GWHSTFALSGLLLLGAAGVTFLLSVKIRSSQRTAINELNA
CCHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHCCC
>Mature Secondary Structure 
SALGHTRAHWSGVLAMTLCVFVLIASEFMPVSLLTPIAGDLHITKGLAGQGIALSGALA
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEEECCCCCCCCHHHHHHH
VLTSLTISRLTGSLDRKWLLLGLTALMAASGVIIALASSFPVYMLGRALIGIVIGGFWSM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHEEECCCCHHHHHHHHHHHHHHHHHHHH
SAATAIRLVPQRQVPRTLAIFNGGNALATVVAAPLGSYLGATVGWCGAFLCLVPLAVLAF
HHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWQCISLPSMKSPRAPQRQGSVLRLFRLSTLSLGLLACGLFFMGQFTLFTYVRPFLETVT
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVSPSGLSLILLTMGIAGFIGTLLITTVLNARFYPTLVAIPLLMAAIAGTLLLAGHHTGS
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
VAVLLSLWGLLATAAPTGWWTWIARTLPEDAETGGGLMVAVIQLSISLGSTVGGLVFDSL
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCC
GWHSTFALSGLLLLGAAGVTFLLSVKIRSSQRTAINELNA
CCHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1427017; 10984043 [H]