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The map label for this gene is talA [H]

Identifier: 152969680

GI number: 152969680

Start: 1277416

End: 1278369

Strand: Direct

Name: talA [H]

Synonym: KPN_01126

Alternate gene names: 152969680

Gene position: 1277416-1278369 (Clockwise)

Preceding gene: 152969679

Following gene: 152969681

Centisome position: 24.03

GC content: 58.07

Gene sequence:

>954_bases
ATGATGAGCCAGTTAGACGAACTGAAAAAATACACCACGGTTGTTGCTGATACCGGCGATATTGAATCGATTAAAAAGTT
TGCACCCCAGGATGCGACCACCAACCCCTCGCTGGTGCTGAAGGCCGCGCAGCTGCCGCAGTATCAGCCGCTGATTGCCG
ATGCGATTGGCAAGGCACGCCGCCAGGGAGGCAGCGCAGAAACGCAATTGATTAACGCCTGCGATCAGGTGGCAGTGGAT
ATCGGCAGCGAGGTGCTGCGCCATGTGCCCGGGCGTATCTCCACCGAAGTGGATGCCCGCTTTGCCTGGGATCGCGGGAT
GTGCGTCGCGAAGGCGCGCAAGCTCATCCAGTTATATGAGAAAAATGGCATTGGTCCCGAGCGGATTTTAATTAAGCTCG
CCGCCACCTGGGAGGGCATTCGCGCTGCCGAAGAGCTGGAGCAGAGCGGTATAAACTGCAACCTGACGCTGCTGTTCTCT
TTCGCTCAGGCCCGGGCGTGCGCCGAAGCGGGCGTCTTTCTCATCTCGCCCTTTGTGGGCCGCATCTACGACTGGTATCA
GAAGCACCAGCCGCAGTCAGCCTATCAGGTGGACAGCGATCCGGGCGTGGTCTCTGTGCGCCAGATTTATCAGTATTACA
AATCACATGGCTATGACACGGTGGTAATGGGTGCCAGCTTCCGTCGTATTGAGCAGATCCAGGCGCTGGCGGGCTGCGAT
CGCCTGACTATCTCTCCGGCACTGCTGGACGAGCTGGCGGCCAGCGAAGGAGTGTTGACCCGCCAGTTGACCCCCGGCTG
CGTGACGGAAACCCGTCCCAGCCCGATGACGCAGGCGGAGTTCCTCTGGCAGCATCATCAGGATCCCATGGCAGTGGAAA
AACTAGCGGAAGGGATCCGACTGTTTGCTGTCGATCAGGTGAAACTGGAACAACAGATTCAGCAGATGCTGTAA

Upstream 100 bases:

>100_bases
ATATGAAGGCGGCGGATCCGCGCCCAAAGTGGAACGTATTGATTATTACGAACACCAGCATGCCAGAGATTAATCTCCGC
AGTCGTAAGATAAGGAACAG

Downstream 100 bases:

>100_bases
GCCGCAGGGATAAAGACTGATGAAGACGACAAAAACCATTCGCTGCCAATGCGCCAACGCGCTGCGCGCCCTGAGCATGG
ACGCTGTACAGAAAGCCAAA

Product: transaldolase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MMSQLDELKKYTTVVADTGDIESIKKFAPQDATTNPSLVLKAAQLPQYQPLIADAIGKARRQGGSAETQLINACDQVAVD
IGSEVLRHVPGRISTEVDARFAWDRGMCVAKARKLIQLYEKNGIGPERILIKLAATWEGIRAAEELEQSGINCNLTLLFS
FAQARACAEAGVFLISPFVGRIYDWYQKHQPQSAYQVDSDPGVVSVRQIYQYYKSHGYDTVVMGASFRRIEQIQALAGCD
RLTISPALLDELAASEGVLTRQLTPGCVTETRPSPMTQAEFLWQHHQDPMAVEKLAEGIRLFAVDQVKLEQQIQQML

Sequences:

>Translated_317_residues
MMSQLDELKKYTTVVADTGDIESIKKFAPQDATTNPSLVLKAAQLPQYQPLIADAIGKARRQGGSAETQLINACDQVAVD
IGSEVLRHVPGRISTEVDARFAWDRGMCVAKARKLIQLYEKNGIGPERILIKLAATWEGIRAAEELEQSGINCNLTLLFS
FAQARACAEAGVFLISPFVGRIYDWYQKHQPQSAYQVDSDPGVVSVRQIYQYYKSHGYDTVVMGASFRRIEQIQALAGCD
RLTISPALLDELAASEGVLTRQLTPGCVTETRPSPMTQAEFLWQHHQDPMAVEKLAEGIRLFAVDQVKLEQQIQQML
>Mature_317_residues
MMSQLDELKKYTTVVADTGDIESIKKFAPQDATTNPSLVLKAAQLPQYQPLIADAIGKARRQGGSAETQLINACDQVAVD
IGSEVLRHVPGRISTEVDARFAWDRGMCVAKARKLIQLYEKNGIGPERILIKLAATWEGIRAAEELEQSGINCNLTLLFS
FAQARACAEAGVFLISPFVGRIYDWYQKHQPQSAYQVDSDPGVVSVRQIYQYYKSHGYDTVVMGASFRRIEQIQALAGCD
RLTISPALLDELAASEGVLTRQLTPGCVTETRPSPMTQAEFLWQHHQDPMAVEKLAEGIRLFAVDQVKLEQQIQQML

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway [H]

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5803187, Length=320, Percent_Identity=55, Blast_Score=359, Evalue=2e-99,
Organism=Escherichia coli, GI1788807, Length=309, Percent_Identity=65.3721682847896, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1786189, Length=317, Percent_Identity=63.4069400630915, Blast_Score=426, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI25153750, Length=321, Percent_Identity=50.7788161993769, Blast_Score=314, Evalue=4e-86,
Organism=Caenorhabditis elegans, GI25153752, Length=167, Percent_Identity=50.8982035928144, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17570473, Length=94, Percent_Identity=47.8723404255319, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323386, Length=319, Percent_Identity=52.0376175548589, Blast_Score=300, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6321480, Length=321, Percent_Identity=46.417445482866, Blast_Score=296, Evalue=3e-81,
Organism=Drosophila melanogaster, GI45549185, Length=319, Percent_Identity=54.858934169279, Blast_Score=347, Evalue=5e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004730
- InterPro:   IPR018225 [H]

Pfam domain/function: PF00923 Transaldolase [H]

EC number: =2.2.1.2 [H]

Molecular weight: Translated: 35171; Mature: 35171

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS01054 TRANSALDOLASE_1 ; PS00958 TRANSALDOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSQLDELKKYTTVVADTGDIESIKKFAPQDATTNPSLVLKAAQLPQYQPLIADAIGKAR
CCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHEEEHHHCCCCCHHHHHHHHHHH
RQGGSAETQLINACDQVAVDIGSEVLRHVPGRISTEVDARFAWDRGMCVAKARKLIQLYE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCCHHHHHHHHHHHHHH
KNGIGPERILIKLAATWEGIRAAEELEQSGINCNLTLLFSFAQARACAEAGVFLISPFVG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHH
RIYDWYQKHQPQSAYQVDSDPGVVSVRQIYQYYKSHGYDTVVMGASFRRIEQIQALAGCD
HHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCC
RLTISPALLDELAASEGVLTRQLTPGCVTETRPSPMTQAEFLWQHHQDPMAVEKLAEGIR
CCEECHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCE
LFAVDQVKLEQQIQQML
EEEHHHHHHHHHHHHHC
>Mature Secondary Structure
MMSQLDELKKYTTVVADTGDIESIKKFAPQDATTNPSLVLKAAQLPQYQPLIADAIGKAR
CCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHEEEHHHCCCCCHHHHHHHHHHH
RQGGSAETQLINACDQVAVDIGSEVLRHVPGRISTEVDARFAWDRGMCVAKARKLIQLYE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCCHHHHHHHHHHHHHH
KNGIGPERILIKLAATWEGIRAAEELEQSGINCNLTLLFSFAQARACAEAGVFLISPFVG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHH
RIYDWYQKHQPQSAYQVDSDPGVVSVRQIYQYYKSHGYDTVVMGASFRRIEQIQALAGCD
HHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCC
RLTISPALLDELAASEGVLTRQLTPGCVTETRPSPMTQAEFLWQHHQDPMAVEKLAEGIR
CCEECHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCE
LFAVDQVKLEQQIQQML
EEEHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA