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The map label for this gene is moaA [H]

Identifier: 152969367

GI number: 152969367

Start: 906015

End: 907004

Strand: Direct

Name: moaA [H]

Synonym: KPN_00810

Alternate gene names: 152969367

Gene position: 906015-907004 (Clockwise)

Preceding gene: 152969361

Following gene: 152969368

Centisome position: 17.05

GC content: 59.7

Gene sequence:

>990_bases
ATGGCCTCACAGCTTACCGATGCATTCGCGCGTAAGTTTTATTACCTGCGTCTGTCGATTACCGATGTGTGCAACTTCCG
TTGCACCTACTGCCTGCCGAACGGTTACAAGCCCGGCGCCGTCAATAACAATGGCTTTCTCAGCGTAGACGAAGTACGCC
GGGTTACGCGCGCTTTCTCCGCGCTGGGCACCGAAAAAGTTCGCCTCACCGGTGGGGAACCCTCCCTGCGCCGCGACTTC
ACCGAGATTATTGCCGCCGTGCGTGAAAACCCAGCGATCCGTCAGATTGCGGTCACTACCAACGGTTACCGCCTGGCGCG
CGATGTCGAACGCTGGCGCGATGCCGGCCTGACGGCGATTAACGTCAGCGTTGATAGCCTCGACGCCCGCCAGTTCCATG
CCATCACCGGCCAGGATAAGTTCCACCAGGTGATGGACGGCATTGACGCCGCCTTCGCCGCCGGCTTTGACAAGGTAAAG
GTGAATACCGTGCTGATGCGTGATGTTAACCATCACCAGCTCGATACCTTCCTCGCCTGGATCCAACCCCGTCGTATCCA
GCTGCGCTTTATTGAGCTGATGGAAACCGGTGAAGGCAGCGACCTGTTCCGCCGTCACCATCTCTCCGGCATGGTGCTGC
GCGATGAACTGCTGCGCCGCGGCTGGATCCATCAGATCCGCCAGCGCAGCGATGGCCCGGCGCAGGTCTTTTGTCACCCG
GACTACGCCGGCGAGATCGGCCTCATCATGCCGTATGAAAAAGACTTCTGCGCCACCTGCAATCGGCTGCGCGTCTCGTC
CGTTGGCAAACTGCACCTGTGCCTGTTTGGCGAAGGCGGCGTCGACCTGCGCGACCTGATGGCCGAAGACCGGCAGCAGG
CCGCGCTTGAGGCGCGGATCGCCGAAGCCTTAACCCATAAAAAGCAGACCCATTTCCTGCATCAGGGCAACACCGGTATT
ACGCAGAACCTGTCCTATATTGGCGGTTAA

Upstream 100 bases:

>100_bases
CGCCTGTGTCAAAAGATATGGCGATTTGGCCGCGACGCCGCCGGTTGTCGCCAGGGCGTGGAAAGAAATGACCGCGTCTC
CCGTATTTGGAAAGGTGTAT

Downstream 100 bases:

>100_bases
TCGTTTTCGAAAGGAGCATTCAGATGAGCCAGGCTAGCGCTGAGTTTATCCCGACCCGTATTGCTATTCTTACCGTTTCC
AGCCGTCGCGGCGAAGAGGA

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPNGYKPGAVNNNGFLSVDEVRRVTRAFSALGTEKVRLTGGEPSLRRDF
TEIIAAVRENPAIRQIAVTTNGYRLARDVERWRDAGLTAINVSVDSLDARQFHAITGQDKFHQVMDGIDAAFAAGFDKVK
VNTVLMRDVNHHQLDTFLAWIQPRRIQLRFIELMETGEGSDLFRRHHLSGMVLRDELLRRGWIHQIRQRSDGPAQVFCHP
DYAGEIGLIMPYEKDFCATCNRLRVSSVGKLHLCLFGEGGVDLRDLMAEDRQQAALEARIAEALTHKKQTHFLHQGNTGI
TQNLSYIGG

Sequences:

>Translated_329_residues
MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPNGYKPGAVNNNGFLSVDEVRRVTRAFSALGTEKVRLTGGEPSLRRDF
TEIIAAVRENPAIRQIAVTTNGYRLARDVERWRDAGLTAINVSVDSLDARQFHAITGQDKFHQVMDGIDAAFAAGFDKVK
VNTVLMRDVNHHQLDTFLAWIQPRRIQLRFIELMETGEGSDLFRRHHLSGMVLRDELLRRGWIHQIRQRSDGPAQVFCHP
DYAGEIGLIMPYEKDFCATCNRLRVSSVGKLHLCLFGEGGVDLRDLMAEDRQQAALEARIAEALTHKKQTHFLHQGNTGI
TQNLSYIGG
>Mature_328_residues
ASQLTDAFARKFYYLRLSITDVCNFRCTYCLPNGYKPGAVNNNGFLSVDEVRRVTRAFSALGTEKVRLTGGEPSLRRDFT
EIIAAVRENPAIRQIAVTTNGYRLARDVERWRDAGLTAINVSVDSLDARQFHAITGQDKFHQVMDGIDAAFAAGFDKVKV
NTVLMRDVNHHQLDTFLAWIQPRRIQLRFIELMETGEGSDLFRRHHLSGMVLRDELLRRGWIHQIRQRSDGPAQVFCHPD
YAGEIGLIMPYEKDFCATCNRLRVSSVGKLHLCLFGEGGVDLRDLMAEDRQQAALEARIAEALTHKKQTHFLHQGNTGIT
QNLSYIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=312, Percent_Identity=37.8205128205128, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI22027536, Length=312, Percent_Identity=37.8205128205128, Blast_Score=213, Evalue=2e-55,
Organism=Escherichia coli, GI1786999, Length=329, Percent_Identity=88.1458966565349, Blast_Score=609, Evalue=1e-176,
Organism=Caenorhabditis elegans, GI32566331, Length=308, Percent_Identity=36.038961038961, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI32566329, Length=308, Percent_Identity=36.038961038961, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17561210, Length=308, Percent_Identity=36.6883116883117, Blast_Score=197, Evalue=4e-51,
Organism=Drosophila melanogaster, GI28574488, Length=313, Percent_Identity=36.4217252396166, Blast_Score=198, Evalue=3e-51,
Organism=Drosophila melanogaster, GI28574490, Length=313, Percent_Identity=36.4217252396166, Blast_Score=198, Evalue=5e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 37196; Mature: 37065

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPNGYKPGAVNNNGFLSVDEVRRVTRAFS
CCCHHHHHHHHHEEEEEEEEEHHCCCEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHH
ALGTEKVRLTGGEPSLRRDFTEIIAAVRENPAIRQIAVTTNGYRLARDVERWRDAGLTAI
HCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEE
NVSVDSLDARQFHAITGQDKFHQVMDGIDAAFAAGFDKVKVNTVLMRDVNHHQLDTFLAW
EEECCCCCCHHEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHH
IQPRRIQLRFIELMETGEGSDLFRRHHLSGMVLRDELLRRGWIHQIRQRSDGPAQVFCHP
HCCCHHHEEEEEHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
DYAGEIGLIMPYEKDFCATCNRLRVSSVGKLHLCLFGEGGVDLRDLMAEDRQQAALEARI
CCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
AEALTHKKQTHFLHQGNTGITQNLSYIGG
HHHHHHHHHHHHHCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
ASQLTDAFARKFYYLRLSITDVCNFRCTYCLPNGYKPGAVNNNGFLSVDEVRRVTRAFS
CCHHHHHHHHHEEEEEEEEEHHCCCEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHH
ALGTEKVRLTGGEPSLRRDFTEIIAAVRENPAIRQIAVTTNGYRLARDVERWRDAGLTAI
HCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEE
NVSVDSLDARQFHAITGQDKFHQVMDGIDAAFAAGFDKVKVNTVLMRDVNHHQLDTFLAW
EEECCCCCCHHEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHH
IQPRRIQLRFIELMETGEGSDLFRRHHLSGMVLRDELLRRGWIHQIRQRSDGPAQVFCHP
HCCCHHHEEEEEHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
DYAGEIGLIMPYEKDFCATCNRLRVSSVGKLHLCLFGEGGVDLRDLMAEDRQQAALEARI
CCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
AEALTHKKQTHFLHQGNTGITQNLSYIGG
HHHHHHHHHHHHHCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA