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The map label for this gene is tolB [H]

Identifier: 152969308

GI number: 152969308

Start: 835226

End: 836482

Strand: Direct

Name: tolB [H]

Synonym: KPN_00744

Alternate gene names: 152969308

Gene position: 835226-836482 (Clockwise)

Preceding gene: 152969307

Following gene: 152969309

Centisome position: 15.71

GC content: 58.79

Gene sequence:

>1257_bases
ATGCTGTGGGCGGCGGTGCTGCACGCAGAAGTACGTATCGAGATCACCCAGGGGGTGGACTCGGCGCGCCCTATCGGCGT
GGTACCGTTCCAGTGGGCCGGCCAGGGCGCTGCGCCGGAAGATGTCGGTGGTATCGTGGCAGCTGACCTGCGCAACAGCG
GTAAATTCAATCCGCTGGATCGCTCTCGTCTGCCGCAGCAGCCGACCAGTGCCCAGGAAGTGCAGCCTGCTGCCTGGTCT
GCGCTGGGTATTGACGCCGTAGTCGTCGGCCAGGTCACGCAAAATCCGGATGGTTCTTATCAGGTTGCGTATCAACTGGT
GGACACCGGCGGAGCGCCGGGCACAACGCTGGCGCAAGGTTCTTTTAAAGTCACTAAGCAGTACCTGCGCTATGCGGCGC
ACGCGGCCAGCGACGCGGTATTTGAGAAGCTGACCGGCATCAAGGGCGCCTTCCGTACCCGTATCGCCTACGTGGTGCAG
AAAAACGGCGGCCAGTACCCTTACGAACTGCGCGTGTCCGACTACGATGGTTACAACCAGTTCCTGGTTCACCGTTCCTC
CCAGCCGCTGATGTCCCCGGCCTGGTCTCCGGACGGTTCTAAACTGGCCTACGTTACCTTTGAAAGCGGTCGTTCTGCGC
TGGTGGTTCAGACCCTGGCGAACGCCTCTGTGCGTCAGATCGCCTCCTTCCCGCAGCACAACGGCGCCCCGGCGTTCTCA
CCGGATGGTTCTAAATTGGCGTTCGCGCTGTCGAAAACCGGTAGCCTGAACCTGTACGTAATGGATCTGGGATCGGGTCA
GATTCGTCAGGTGACCAACGGTCGCAGCAACAACACCGAACCAAGCTGGTTCCCGGACAGCCAGAATCTGGCCTTCACTT
CTGACCAGGCAGGTCGTCCGCAGGTATATAAAGTCAACATTAATGGCGGCACGCCGCAGCGTATCACCTGGGAAGGTTCT
CAGAACCAGGACGCCGACGTGAGCGCGGATGGTAAAACCATGGTAATGGTCAGCTCGGCCGGCGGTCAGCAGCACATTGC
CAAACAAGATCTGGAAACGGGTGGTGTACAGGTTCTGTCATCAACGTTTTTAGACGAAACGCCAAGTCTGGCACCTAACG
GCACTATGGTAATCTACAGCTCTTCTCAGGGGATGGGATCCGTGCTGAATCTGGTTTCTACAGATGGGCGTTTCAAAGCG
CGTCTTCCGGCAACTGATGGACAGGTAAAATCGCCTGCCTGGTCGCCGTATCTGTGA

Upstream 100 bases:

>100_bases
TATTTGAGTTTGTTAACATTCTGCTAAATTATCGTGGGCTTTCCGCCCGGATAAGGGAGATATGATGAAGCAGGCATTAC
GAGTAGCATTTGGTTTTTTA

Downstream 100 bases:

>100_bases
TAATAAATAATTGATTATTAAAGGAATCAAAGAAATGCAACTGAACAAAGTGCTGAAAGGGCTGATGATCGCTCTGCCGG
TTATGGCAATCGCGGCATGT

Product: translocation protein TolB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MLWAAVLHAEVRIEITQGVDSARPIGVVPFQWAGQGAAPEDVGGIVAADLRNSGKFNPLDRSRLPQQPTSAQEVQPAAWS
ALGIDAVVVGQVTQNPDGSYQVAYQLVDTGGAPGTTLAQGSFKVTKQYLRYAAHAASDAVFEKLTGIKGAFRTRIAYVVQ
KNGGQYPYELRVSDYDGYNQFLVHRSSQPLMSPAWSPDGSKLAYVTFESGRSALVVQTLANASVRQIASFPQHNGAPAFS
PDGSKLAFALSKTGSLNLYVMDLGSGQIRQVTNGRSNNTEPSWFPDSQNLAFTSDQAGRPQVYKVNINGGTPQRITWEGS
QNQDADVSADGKTMVMVSSAGGQQHIAKQDLETGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKA
RLPATDGQVKSPAWSPYL

Sequences:

>Translated_418_residues
MLWAAVLHAEVRIEITQGVDSARPIGVVPFQWAGQGAAPEDVGGIVAADLRNSGKFNPLDRSRLPQQPTSAQEVQPAAWS
ALGIDAVVVGQVTQNPDGSYQVAYQLVDTGGAPGTTLAQGSFKVTKQYLRYAAHAASDAVFEKLTGIKGAFRTRIAYVVQ
KNGGQYPYELRVSDYDGYNQFLVHRSSQPLMSPAWSPDGSKLAYVTFESGRSALVVQTLANASVRQIASFPQHNGAPAFS
PDGSKLAFALSKTGSLNLYVMDLGSGQIRQVTNGRSNNTEPSWFPDSQNLAFTSDQAGRPQVYKVNINGGTPQRITWEGS
QNQDADVSADGKTMVMVSSAGGQQHIAKQDLETGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKA
RLPATDGQVKSPAWSPYL
>Mature_418_residues
MLWAAVLHAEVRIEITQGVDSARPIGVVPFQWAGQGAAPEDVGGIVAADLRNSGKFNPLDRSRLPQQPTSAQEVQPAAWS
ALGIDAVVVGQVTQNPDGSYQVAYQLVDTGGAPGTTLAQGSFKVTKQYLRYAAHAASDAVFEKLTGIKGAFRTRIAYVVQ
KNGGQYPYELRVSDYDGYNQFLVHRSSQPLMSPAWSPDGSKLAYVTFESGRSALVVQTLANASVRQIASFPQHNGAPAFS
PDGSKLAFALSKTGSLNLYVMDLGSGQIRQVTNGRSNNTEPSWFPDSQNLAFTSDQAGRPQVYKVNINGGTPQRITWEGS
QNQDADVSADGKTMVMVSSAGGQQHIAKQDLETGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKA
RLPATDGQVKSPAWSPYL

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0823

COG function: function code U; Periplasmic component of the Tol biopolymer transport system

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tolB family [H]

Homologues:

Organism=Escherichia coli, GI1786961, Length=418, Percent_Identity=90.9090909090909, Blast_Score=777, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32564217, Length=177, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI32564215, Length=177, Percent_Identity=27.1186440677966, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011659
- InterPro:   IPR014167
- InterPro:   IPR007195
- InterPro:   IPR015943 [H]

Pfam domain/function: PF07676 PD40; PF04052 TolB_N [H]

EC number: NA

Molecular weight: Translated: 44550; Mature: 44550

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWAAVLHAEVRIEITQGVDSARPIGVVPFQWAGQGAAPEDVGGIVAADLRNSGKFNPLD
CEEEEEEEEEEEEEEECCCCCCCCCEEEEECCCCCCCCCHHHCCEEEEECCCCCCCCCCC
RSRLPQQPTSAQEVQPAAWSALGIDAVVVGQVTQNPDGSYQVAYQLVDTGGAPGTTLAQG
HHHCCCCCCCHHHCCCCHHHHCCCCEEEEEEEECCCCCCEEEEEEEEECCCCCCCEEECC
SFKVTKQYLRYAAHAASDAVFEKLTGIKGAFRTRIAYVVQKNGGQYPYELRVSDYDGYNQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEEEEECCCCCCCEEEEEECCCCCCE
FLVHRSSQPLMSPAWSPDGSKLAYVTFESGRSALVVQTLANASVRQIASFPQHNGAPAFS
EEEECCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEHHCHHHHHHHHCCCCCCCCCCC
PDGSKLAFALSKTGSLNLYVMDLGSGQIRQVTNGRSNNTEPSWFPDSQNLAFTSDQAGRP
CCCCEEEEEEECCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCC
QVYKVNINGGTPQRITWEGSQNQDADVSADGKTMVMVSSAGGQQHIAKQDLETGGVQVLS
EEEEEEECCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHH
STFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKSPAWSPYL
HHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLWAAVLHAEVRIEITQGVDSARPIGVVPFQWAGQGAAPEDVGGIVAADLRNSGKFNPLD
CEEEEEEEEEEEEEEECCCCCCCCCEEEEECCCCCCCCCHHHCCEEEEECCCCCCCCCCC
RSRLPQQPTSAQEVQPAAWSALGIDAVVVGQVTQNPDGSYQVAYQLVDTGGAPGTTLAQG
HHHCCCCCCCHHHCCCCHHHHCCCCEEEEEEEECCCCCCEEEEEEEEECCCCCCCEEECC
SFKVTKQYLRYAAHAASDAVFEKLTGIKGAFRTRIAYVVQKNGGQYPYELRVSDYDGYNQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEEEEECCCCCCCEEEEEECCCCCCE
FLVHRSSQPLMSPAWSPDGSKLAYVTFESGRSALVVQTLANASVRQIASFPQHNGAPAFS
EEEECCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEHHCHHHHHHHHCCCCCCCCCCC
PDGSKLAFALSKTGSLNLYVMDLGSGQIRQVTNGRSNNTEPSWFPDSQNLAFTSDQAGRP
CCCCEEEEEEECCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCC
QVYKVNINGGTPQRITWEGSQNQDADVSADGKTMVMVSSAGGQQHIAKQDLETGGVQVLS
EEEEEEECCCCCCEEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHH
STFLDETPSLAPNGTMVIYSSSQGMGSVLNLVSTDGRFKARLPATDGQVKSPAWSPYL
HHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA