| Definition | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 chromosome, complete genome. |
|---|---|
| Accession | NC_009648 |
| Length | 5,315,120 |
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The map label for this gene is nagE [H]
Identifier: 152969264
GI number: 152969264
Start: 786056
End: 788011
Strand: Direct
Name: nagE [H]
Synonym: KPN_00700
Alternate gene names: 152969264
Gene position: 786056-788011 (Clockwise)
Preceding gene: 152969258
Following gene: 152969265
Centisome position: 14.79
GC content: 59.82
Gene sequence:
>1956_bases ATGAATATTTTAGGTTTCTTTCAGCGACTGGGTAGGGCGTTGCAGCTCCCTATCGCAGTGCTGCCGGTCGCGGCATTGCT GCTGCGTTTCGGGCAACCAGACCTGTTGAATGTACCCTTCATCGCGCAAGCGGGTGGGGCGATCTTCGATAATCTGGCGC TGATCTTCGCAATTGGTGTGGCATCAAGCTGGTCTAAGGATAACGCCGGTTCTGCGGCGCTGGCCGGTGCGGTAGGGTAT TTCGTGATGACCAAAGCGATGGTCACCATCAACCCGGAAATCAATATGGGCGTGCTGGCCGGTATCATTACCGGTCTGGT GGCAGGGGCGGTATACAACCGCTGGGCCGGCATCAAGCTGCCGGACTTCCTGAGCTTCTTCGGCGGCAAACGCTTCGTGC CGATCGCCACCGGCTTCTTCTGTCTGATCCTCGCGGCGATCTTCGGCTACGTCTGGCCGCCGGTGCAGCACGCTATCCAC TCTGGCGGCGAATGGATCGTCTCCGCAGGGGCGCTCGGTTCCGGTATCTTTGGTTTCATCAACCGTCTGCTGATCCCAAC CGGTCTGCATCAGGTGCTGAACACCATCGCCTGGTTCCAGATTGGTGAGTTCACTAACGCCGCTGGCGCTGTGTTCCACG GCGACATCAACCGCTTCTACGCCGGCGACGGCACCGCGGGGATGTTCATGTCCGGCTTCTTCCCAATCATGATGTTTGGT CTGCCGGGTGCGGCGCTGGCGATGTATCTGGCGGCGCCGAAAGCGCGTCGTCCGATGGTAGGCGGTATGCTGCTGTCCGT GGCCATCACCGCGTTCCTGACCGGGGTAACCGAGCCGCTGGAATTCCTGTTCATGTTCCTGGCTCCGCTGCTGTACCTCC TGCATGCGGTGCTGACCGGTATCAGCCTGTTCATCGCAACGGCGCTCGGGATCCATGCGGGCTTCTCCTTCTCCGCAGGT GCAATTGACTACGTGCTGATGTACAGCCTGCCGGCCGCCAGCAAAAACGTCTGGATGCTGCTGGTGATGGGCGTGGTGTT CTTCTTCGTCTACTTCCTGCTGTTCAGCGCGGTGATCCGCATGTTCAACCTGAAAACGCCGGGTCGTGAAGACAAAGCCG CTGACGTGGTAACGGAAGAAGCCAACAGCAACACTGAAGAGGGGCTGACCCAGCTGGCGACCAGCTATATCGCCGCGGTG GGCGGAACAGACAACCTGAAAGCCATTGACGCCTGTATCACCCGTCTGCGTCTGACCGTGGGCGATTCGGCGAAGGTGAA CGACGCCGCCTGTAAACGTCTCGGCGCGTCCGGGGTGGTGAAACTGAATAAGCAAACCATTCAGGTTATCGTCGGTGCGA AAGCAGAGTCTATCGGCGATGAGATGAAAAAAGTGGTTACCCGCGGCCCGGTAGCGGCAGCGGCAGCCGCACCGGCTGGC AACGTCGCCACCGCAGCGCCCGCGGCTAAACCGCAGGCGGTAGCGAACGCGAAGACCGTTGAGTCGCTGGTTTCGCCGAT TACCGGTGACGTGGTGGCCCTCGAGCAGGTGCCGGACGAAGCCTTCGCCAGCAAAGCCGTTGGCGACGGGATCGCGGTGA AACCGACCAGCAACATCGTGGTGGCCCCGGCCGCCGGTACCGTGGTGAAAATTTTCAACACTAACCACGCGTTCTGCCTC GAAACCAACAACGGTGCGGAAATCGTCGTTCACATGGGTATCGACACCGTGGCGCTGGAAGGCAAGGGCTTCAAACGTCT GGTTGAAGAGGGCACGGACGTGAAGGCGGGTGAGCCGATTCTGGAAATGGATCTGGACTTCCTCAACGCCAACGCGCGCT CAATGATCAGTCCGGTCGTCTGCAGCAACAGCGATGACTACAGCGCGCTGGTGATACTGGCGAGCGGTAAGGTCGTTGCT GGCCAGACGCCGCTGTATGAGATTAAAGGCAAGTAA
Upstream 100 bases:
>100_bases TTTTCACACACTTTGCCGGTAAGTGATAAAACCGACCTTGTTACACAATAAAAAAGTGGCTTTGAAATGAGCCTCATCGG GGTCTCATAGGGGGAATAAG
Downstream 100 bases:
>100_bases GGCTCCTGAGTCGAGTTTTTGCCTCAGCGGCGAAGGGAAACCTTCGCCGCTTTTTTTTCCAGCAATCGGCCCCATAATCC TCTTCTGATACCTATTTTAC
Product: PTS system N-acetyl glucosamine specific transporter subunits IIABC
Products: NA
Alternate protein names: EIICBA-Nag; EII-Nag; N-acetylglucosamine permease IIC component; PTS system N-acetylglucosamine-specific EIIC component; N-acetylglucosamine-specific phosphotransferase enzyme IIB component; PTS system N-acetylglucosamine-specific EIIB component; N-acetylglucosamine-specific phosphotransferase enzyme IIA component; PTS system N-acetylglucosamine-specific EIIA component [H]
Number of amino acids: Translated: 651; Mature: 651
Protein sequence:
>651_residues MNILGFFQRLGRALQLPIAVLPVAALLLRFGQPDLLNVPFIAQAGGAIFDNLALIFAIGVASSWSKDNAGSAALAGAVGY FVMTKAMVTINPEINMGVLAGIITGLVAGAVYNRWAGIKLPDFLSFFGGKRFVPIATGFFCLILAAIFGYVWPPVQHAIH SGGEWIVSAGALGSGIFGFINRLLIPTGLHQVLNTIAWFQIGEFTNAAGAVFHGDINRFYAGDGTAGMFMSGFFPIMMFG LPGAALAMYLAAPKARRPMVGGMLLSVAITAFLTGVTEPLEFLFMFLAPLLYLLHAVLTGISLFIATALGIHAGFSFSAG AIDYVLMYSLPAASKNVWMLLVMGVVFFFVYFLLFSAVIRMFNLKTPGREDKAADVVTEEANSNTEEGLTQLATSYIAAV GGTDNLKAIDACITRLRLTVGDSAKVNDAACKRLGASGVVKLNKQTIQVIVGAKAESIGDEMKKVVTRGPVAAAAAAPAG NVATAAPAAKPQAVANAKTVESLVSPITGDVVALEQVPDEAFASKAVGDGIAVKPTSNIVVAPAAGTVVKIFNTNHAFCL ETNNGAEIVVHMGIDTVALEGKGFKRLVEEGTDVKAGEPILEMDLDFLNANARSMISPVVCSNSDDYSALVILASGKVVA GQTPLYEIKGK
Sequences:
>Translated_651_residues MNILGFFQRLGRALQLPIAVLPVAALLLRFGQPDLLNVPFIAQAGGAIFDNLALIFAIGVASSWSKDNAGSAALAGAVGY FVMTKAMVTINPEINMGVLAGIITGLVAGAVYNRWAGIKLPDFLSFFGGKRFVPIATGFFCLILAAIFGYVWPPVQHAIH SGGEWIVSAGALGSGIFGFINRLLIPTGLHQVLNTIAWFQIGEFTNAAGAVFHGDINRFYAGDGTAGMFMSGFFPIMMFG LPGAALAMYLAAPKARRPMVGGMLLSVAITAFLTGVTEPLEFLFMFLAPLLYLLHAVLTGISLFIATALGIHAGFSFSAG AIDYVLMYSLPAASKNVWMLLVMGVVFFFVYFLLFSAVIRMFNLKTPGREDKAADVVTEEANSNTEEGLTQLATSYIAAV GGTDNLKAIDACITRLRLTVGDSAKVNDAACKRLGASGVVKLNKQTIQVIVGAKAESIGDEMKKVVTRGPVAAAAAAPAG NVATAAPAAKPQAVANAKTVESLVSPITGDVVALEQVPDEAFASKAVGDGIAVKPTSNIVVAPAAGTVVKIFNTNHAFCL ETNNGAEIVVHMGIDTVALEGKGFKRLVEEGTDVKAGEPILEMDLDFLNANARSMISPVVCSNSDDYSALVILASGKVVA GQTPLYEIKGK >Mature_651_residues MNILGFFQRLGRALQLPIAVLPVAALLLRFGQPDLLNVPFIAQAGGAIFDNLALIFAIGVASSWSKDNAGSAALAGAVGY FVMTKAMVTINPEINMGVLAGIITGLVAGAVYNRWAGIKLPDFLSFFGGKRFVPIATGFFCLILAAIFGYVWPPVQHAIH SGGEWIVSAGALGSGIFGFINRLLIPTGLHQVLNTIAWFQIGEFTNAAGAVFHGDINRFYAGDGTAGMFMSGFFPIMMFG LPGAALAMYLAAPKARRPMVGGMLLSVAITAFLTGVTEPLEFLFMFLAPLLYLLHAVLTGISLFIATALGIHAGFSFSAG AIDYVLMYSLPAASKNVWMLLVMGVVFFFVYFLLFSAVIRMFNLKTPGREDKAADVVTEEANSNTEEGLTQLATSYIAAV GGTDNLKAIDACITRLRLTVGDSAKVNDAACKRLGASGVVKLNKQTIQVIVGAKAESIGDEMKKVVTRGPVAAAAAAPAG NVATAAPAAKPQAVANAKTVESLVSPITGDVVALEQVPDEAFASKAVGDGIAVKPTSNIVVAPAAGTVVKIFNTNHAFCL ETNNGAEIVVHMGIDTVALEGKGFKRLVEEGTDVKAGEPILEMDLDFLNANARSMISPVVCSNSDDYSALVILASGKVVA GQTPLYEIKGK
Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This
COG id: COG1263
COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIC type-1 domain [H]
Homologues:
Organism=Escherichia coli, GI1786894, Length=649, Percent_Identity=88.9060092449923, Blast_Score=1106, Evalue=0.0, Organism=Escherichia coli, GI1787343, Length=485, Percent_Identity=42.0618556701031, Blast_Score=377, Evalue=1e-106, Organism=Escherichia coli, GI1787908, Length=510, Percent_Identity=33.921568627451, Blast_Score=258, Evalue=6e-70, Organism=Escherichia coli, GI1788757, Length=151, Percent_Identity=52.317880794702, Blast_Score=161, Evalue=1e-40, Organism=Escherichia coli, GI1790159, Length=166, Percent_Identity=36.144578313253, Blast_Score=112, Evalue=1e-25,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011055 - InterPro: IPR018113 - InterPro: IPR004719 - InterPro: IPR001127 - InterPro: IPR001996 - InterPro: IPR003352 - InterPro: IPR013013 - InterPro: IPR011535 - InterPro: IPR010974 [H]
Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 68140; Mature: 68140
Theoretical pI: Translated: 6.94; Mature: 6.94
Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNILGFFQRLGRALQLPIAVLPVAALLLRFGQPDLLNVPFIAQAGGAIFDNLALIFAIGV CCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHH ASSWSKDNAGSAALAGAVGYFVMTKAMVTINPEINMGVLAGIITGLVAGAVYNRWAGIKL CCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC PDFLSFFGGKRFVPIATGFFCLILAAIFGYVWPPVQHAIHSGGEWIVSAGALGSGIFGFI HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCCCHHHHHH NRLLIPTGLHQVLNTIAWFQIGEFTNAAGAVFHGDINRFYAGDGTAGMFMSGFFPIMMFG HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEECCCCCHHHHHHHHHHHHHHC LPGAALAMYLAAPKARRPMVGGMLLSVAITAFLTGVTEPLEFLFMFLAPLLYLLHAVLTG CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH ISLFIATALGIHAGFSFSAGAIDYVLMYSLPAASKNVWMLLVMGVVFFFVYFLLFSAVIR HHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH MFNLKTPGREDKAADVVTEEANSNTEEGLTQLATSYIAAVGGTDNLKAIDACITRLRLTV HHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEE GDSAKVNDAACKRLGASGVVKLNKQTIQVIVGAKAESIGDEMKKVVTRGPVAAAAAAPAG CCCCCCCHHHHHHCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHHHCCCCHHHHCCCCC NVATAAPAAKPQAVANAKTVESLVSPITGDVVALEQVPDEAFASKAVGDGIAVKPTSNIV CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHCCCHHHHHHHCCCCEEECCCCCEE VAPAAGTVVKIFNTNHAFCLETNNGAEIVVHMGIDTVALEGKGFKRLVEEGTDVKAGEPI EEECCCCEEEEEECCCEEEEECCCCCEEEEEECCCEEEECCCCHHHHHHCCCCCCCCCCH LEMDLDFLNANARSMISPVVCSNSDDYSALVILASGKVVAGQTPLYEIKGK HHHHHHHHCCCHHHHHCCHHCCCCCCCEEEEEEECCCEEECCCCCEEECCC >Mature Secondary Structure MNILGFFQRLGRALQLPIAVLPVAALLLRFGQPDLLNVPFIAQAGGAIFDNLALIFAIGV CCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHH ASSWSKDNAGSAALAGAVGYFVMTKAMVTINPEINMGVLAGIITGLVAGAVYNRWAGIKL CCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC PDFLSFFGGKRFVPIATGFFCLILAAIFGYVWPPVQHAIHSGGEWIVSAGALGSGIFGFI HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCCCHHHHHH NRLLIPTGLHQVLNTIAWFQIGEFTNAAGAVFHGDINRFYAGDGTAGMFMSGFFPIMMFG HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEECCCCCHHHHHHHHHHHHHHC LPGAALAMYLAAPKARRPMVGGMLLSVAITAFLTGVTEPLEFLFMFLAPLLYLLHAVLTG CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH ISLFIATALGIHAGFSFSAGAIDYVLMYSLPAASKNVWMLLVMGVVFFFVYFLLFSAVIR HHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH MFNLKTPGREDKAADVVTEEANSNTEEGLTQLATSYIAAVGGTDNLKAIDACITRLRLTV HHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEE GDSAKVNDAACKRLGASGVVKLNKQTIQVIVGAKAESIGDEMKKVVTRGPVAAAAAAPAG CCCCCCCHHHHHHCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHHHCCCCHHHHCCCCC NVATAAPAAKPQAVANAKTVESLVSPITGDVVALEQVPDEAFASKAVGDGIAVKPTSNIV CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHCCCHHHHHHHCCCCEEECCCCCEE VAPAAGTVVKIFNTNHAFCLETNNGAEIVVHMGIDTVALEGKGFKRLVEEGTDVKAGEPI EEECCCCEEEEEECCCEEEEECCCCCEEEEEECCCEEEECCCCHHHHHHCCCCCCCCCCH LEMDLDFLNANARSMISPVVCSNSDDYSALVILASGKVVAGQTPLYEIKGK HHHHHHHHCCCHHHHHCCHHCCCCCCCEEEEEEECCCEEECCCCCEEECCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 1745234 [H]