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The map label for this gene is entC [H]

Identifier: 152969182

GI number: 152969182

Start: 692482

End: 693657

Strand: Direct

Name: entC [H]

Synonym: KPN_00611

Alternate gene names: 152969182

Gene position: 692482-693657 (Clockwise)

Preceding gene: 152969180

Following gene: 152969183

Centisome position: 13.03

GC content: 65.22

Gene sequence:

>1176_bases
ATGGAAACGTCACTGGCTGAGGATGTAAAGAAACCGACCCGGACCCTGTCGCCGGACAGCTTCTTCTTTATGTCGCCGTA
CCGCAGTTTTACCACTTCAGGCTGCTTCCGTCGCTTCTCACAGCCCGCCGTTGGCGGCGATGCGCTGAACGGCGAGTTCC
AGCAGCAGATGGCGGCCGCCTTTGCCGAGGCCCGGGCGGCGGGGATCCGCAAGCCGGTGATGGTCGGGGCTATCCCGTTC
GACACCTGTCAGCCTTCCGAGCTCTATATCCCCGAGCGCTGGGAAGCGTTCTCTCGCCCGGAAAAGCAGCGTTCCGCCCG
CTATGCCGCGCCGCTGGAGGCGATGGAGGTGGTGGAGCGTCGGGAGATCCCGGAGCAGGACGCGTTTTTAGCCATGGTGG
AACGCGCCGCCGCGCTGACCGCCACCCCGGAAGTCGACAAAGTGGTGCTATCAAGGCTTATCGATATTACCACCCGCGAC
CGCGTCGACAGCGGCGCGCTGATGGAGCGACTGATCGCCCAGAACCCCGCCAGCTTTAACTTCCACGTGCCGCTCTCCGA
CGGCGGCGTGCTGCTGGGCGCCAGCCCGGAGCTGCTGCTGCGTAAAGAAGGACAGCACTTCAGCTCTCTGCCGCTGGCCG
GCTCCGCCCGTCGCCAGCCGGACGATGTGCTGGACCGGGAAGCAGGCAACAGGCTGTTGGCCTCCGGCAAAGATCGCCAC
GAGCACGAGCTGGTGACCCAGGCGATGAAGAGCGTGCTGGGCCCGCGCAGCAGTCAGCTGTCGCTACCGGAGTCGCCGCA
GCTGATTACCACCCCGACGCTCTGGCATCTGGCGACGCCGATCGCAGGCACCGCGCTGGCGGAAGAAAACGCCATGTCGC
TGGCCTGTCTGCTGCACCCGACGCCGGCGCTGAGCGGTTTCCCGCATCAGGCGGCGAAGCGCCTGATTGCTGAACTGGAA
CCCTTCGATCGCCAGCTGTTCGGCGGCATCGTCGGCTGGTGCGATGACGAAGGCAACGGCGAGTGGGTGGTGACTATCCG
CTGCGCGCGTCTGCAGCAGCGTACGCTGCGCCTGTTTGCCGGCGCGGGCATTGTTCCGGCCTCCTCGCCGCTGGGCGAAT
GGCGCGAAACCGGCGTCAAACTGACCACCATGCTTAACGTATTTGGCTTGAACTAA

Upstream 100 bases:

>100_bases
ACGTAACGCGGTTGACATGGCGGGCAATACCTTTTAGGTTAGCCAACCAAAATATAAATGATAATTATTCTTAATATCTT
TATCGTTTTTGGAGGATGAT

Downstream 100 bases:

>100_bases
GAGGCAAGGATGATTGCATTTACCCGTTGGCCGGAAGAGTTTGCGGCCCGCTATCGTCAAAAAGGCTACTGGCAGGATCT
GCCGTTAACCAATCTGATCA

Product: isochorismate synthase

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
METSLAEDVKKPTRTLSPDSFFFMSPYRSFTTSGCFRRFSQPAVGGDALNGEFQQQMAAAFAEARAAGIRKPVMVGAIPF
DTCQPSELYIPERWEAFSRPEKQRSARYAAPLEAMEVVERREIPEQDAFLAMVERAAALTATPEVDKVVLSRLIDITTRD
RVDSGALMERLIAQNPASFNFHVPLSDGGVLLGASPELLLRKEGQHFSSLPLAGSARRQPDDVLDREAGNRLLASGKDRH
EHELVTQAMKSVLGPRSSQLSLPESPQLITTPTLWHLATPIAGTALAEENAMSLACLLHPTPALSGFPHQAAKRLIAELE
PFDRQLFGGIVGWCDDEGNGEWVVTIRCARLQQRTLRLFAGAGIVPASSPLGEWRETGVKLTTMLNVFGLN

Sequences:

>Translated_391_residues
METSLAEDVKKPTRTLSPDSFFFMSPYRSFTTSGCFRRFSQPAVGGDALNGEFQQQMAAAFAEARAAGIRKPVMVGAIPF
DTCQPSELYIPERWEAFSRPEKQRSARYAAPLEAMEVVERREIPEQDAFLAMVERAAALTATPEVDKVVLSRLIDITTRD
RVDSGALMERLIAQNPASFNFHVPLSDGGVLLGASPELLLRKEGQHFSSLPLAGSARRQPDDVLDREAGNRLLASGKDRH
EHELVTQAMKSVLGPRSSQLSLPESPQLITTPTLWHLATPIAGTALAEENAMSLACLLHPTPALSGFPHQAAKRLIAELE
PFDRQLFGGIVGWCDDEGNGEWVVTIRCARLQQRTLRLFAGAGIVPASSPLGEWRETGVKLTTMLNVFGLN
>Mature_391_residues
METSLAEDVKKPTRTLSPDSFFFMSPYRSFTTSGCFRRFSQPAVGGDALNGEFQQQMAAAFAEARAAGIRKPVMVGAIPF
DTCQPSELYIPERWEAFSRPEKQRSARYAAPLEAMEVVERREIPEQDAFLAMVERAAALTATPEVDKVVLSRLIDITTRD
RVDSGALMERLIAQNPASFNFHVPLSDGGVLLGASPELLLRKEGQHFSSLPLAGSARRQPDDVLDREAGNRLLASGKDRH
EHELVTQAMKSVLGPRSSQLSLPESPQLITTPTLWHLATPIAGTALAEENAMSLACLLHPTPALSGFPHQAAKRLIAELE
PFDRQLFGGIVGWCDDEGNGEWVVTIRCARLQQRTLRLFAGAGIVPASSPLGEWRETGVKLTTMLNVFGLN

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=391, Percent_Identity=75.7033248081841, Blast_Score=615, Evalue=1e-177,
Organism=Escherichia coli, GI87082077, Length=283, Percent_Identity=31.095406360424, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1788114, Length=214, Percent_Identity=27.5700934579439, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787518, Length=229, Percent_Identity=28.3842794759825, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320935, Length=213, Percent_Identity=27.6995305164319, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 42819; Mature: 42819

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METSLAEDVKKPTRTLSPDSFFFMSPYRSFTTSGCFRRFSQPAVGGDALNGEFQQQMAAA
CCCCHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
FAEARAAGIRKPVMVGAIPFDTCQPSELYIPERWEAFSRPEKQRSARYAAPLEAMEVVER
HHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHCCCHHHHHHHHH
REIPEQDAFLAMVERAAALTATPEVDKVVLSRLIDITTRDRVDSGALMERLIAQNPASFN
HCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEE
FHVPLSDGGVLLGASPELLLRKEGQHFSSLPLAGSARRQPDDVLDREAGNRLLASGKDRH
EEEECCCCCEEEECCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHCCCCHH
EHELVTQAMKSVLGPRSSQLSLPESPQLITTPTLWHLATPIAGTALAEENAMSLACLLHP
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHCCHHHHHHHCCCCCEEEEEECC
TPALSGFPHQAAKRLIAELEPFDRQLFGGIVGWCDDEGNGEWVVTIRCARLQQRTLRLFA
CCCCCCCCHHHHHHHHHHCCHHHHHHHCCCEEEECCCCCCCEEEEEEHHHHHHHHHHHHH
GAGIVPASSPLGEWRETGVKLTTMLNVFGLN
CCCCCCCCCCHHHHHHCCEEHHHHHHHHCCC
>Mature Secondary Structure
METSLAEDVKKPTRTLSPDSFFFMSPYRSFTTSGCFRRFSQPAVGGDALNGEFQQQMAAA
CCCCHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
FAEARAAGIRKPVMVGAIPFDTCQPSELYIPERWEAFSRPEKQRSARYAAPLEAMEVVER
HHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHCCCHHHHHHHHH
REIPEQDAFLAMVERAAALTATPEVDKVVLSRLIDITTRDRVDSGALMERLIAQNPASFN
HCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEE
FHVPLSDGGVLLGASPELLLRKEGQHFSSLPLAGSARRQPDDVLDREAGNRLLASGKDRH
EEEECCCCCEEEECCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHCCCCHH
EHELVTQAMKSVLGPRSSQLSLPESPQLITTPTLWHLATPIAGTALAEENAMSLACLLHP
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHCCHHHHHHHCCCCCEEEEEECC
TPALSGFPHQAAKRLIAELEPFDRQLFGGIVGWCDDEGNGEWVVTIRCARLQQRTLRLFA
CCCCCCCCHHHHHHHHHHCCHHHHHHHCCCEEEECCCCCCCEEEEEEHHHHHHHHHHHHH
GAGIVPASSPLGEWRETGVKLTTMLNVFGLN
CCCCCCCCCCHHHHHHCCEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]