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The map label for this gene is dppA [H]

Identifier: 152969135

GI number: 152969135

Start: 634576

End: 636243

Strand: Direct

Name: dppA [H]

Synonym: KPN_00564

Alternate gene names: 152969135

Gene position: 634576-636243 (Clockwise)

Preceding gene: 152969132

Following gene: 152969136

Centisome position: 11.94

GC content: 61.93

Gene sequence:

>1668_bases
ATGCACAAAAAGACGTTATTTTCGCGTGCCGGTCGTCTCGCCGTGGCGGTGAGCGGCGCACTGGCCCTGGCGGGCGCCGC
CTTACCTGCCAACGCCTCCACGCTGCGGATCGCCATGACCGCCGCGGATATTCCATTAACCCTTGGCCAGCCGGATCAAG
GCTATGAGGGCAACCGCTTTACCGGCATCCCGCTGTACGACGCGCTGGTGGAGTGGGATCTGTCGCAAGGTGAAAAGCCC
AGCGGTCTGGTGCCGGGGCTGGCGACCGAGTGGCACATCGATCCGCAGAATACCAGCCGCTGGATTTTCACCCTGCGTCC
GGGGGTGAAGTTTCATGATGGGACGGAGGTGAACGCCGACGCCATCGTCTGGAACGTGGATAAGGTACTGAATAAAGCGG
CGCCGCAGTACGCCCCGGGTCAGATCGGCAACACCCTGTCGCGCATGCCGACCCTCACCGGCGCAGAGAAAATTGACGAC
CACACCGTGGCGCTGACCACCTCGGAACCGGATGCGCTGCTGCCGTACAACATCACCAACCTGTTTATCGTCTCGCCGAC
GGCGTGGCAGAAGCAGTATGACGCGGTGCCGGCCAGCGTGGGAGATAGCGCCGCGCGCAGCAAACAGGCGTGGACCGCCT
TCGCCGCCCACGCGGTGGGTAGCGGCCCGTTCAAACTGGAGAAGCTGGTGCCGCGTCAGCAGCTGATCCTCGATAAAAAC
CCCGACTACTGGAACAAAGATCGCATTCCCCGGGTGGATAAAGTGGTGCTGATCCCCTTGCCGGAGGCCAACGCCCGTAC
CGCGGCGCTGTTGTCGAAGCAGGTGGACTGGATTGAAGCCCCGGCGCCGGACGCCATCGATCAGATCAAGTCTCAGGGTT
TTCACCTCTACGCCAACACCCAGCCGCATCTGTGGCCCTGGCAGTTCTCCTTTGAAAAAGGATCGCCGTGGCAGGACATC
CGCGTGCGCAAAGCGGCCAACTTGTGTCTGAACCGTGCTGAGCTGAAGAGCTACCTCGGCGGCTATATGACCGAGGCCAC
TGGGGTCTACGAGGCTGACAGCCCGTGGCATGGCAAACCCACCTTCCAGATCAAATATGACCCGGACGTCGCCCGCCAGC
TAATGACCGAGGCCGGATACAGTGCCAGCAAACCGCTGCACGTCACGGTGGCTACCTCGGCCTCCGGCTCCGGGCAGATG
CAGCCCTTGCCGATGAACGAGTATATCCAGCAGAGCCTGAAGAGCTGCTTCTTCAATGTGGATATCAAAGTGGTGGAATG
GAACACCCTGTTTACCAACTGGCGCCTGGGCGCCCGGGACCCCTCGGCGAAAGGGATCGATGCGATCAACGTCAGCGCCG
CGGTTAACGATCCTTACTTTGGCCTGATCCGCTTCTCGACGGCCAAAGCGTTTCCGCCGGTGGCGACCAACTGGGGTTAC
TTTTCCACGCCGGAGACGGAGAAGCTGGCCGCCGCCGTCAAGCACGCCTTTACCCCGGCGGAGATGAACAAAGCGGCCGG
TGAGTTGCACGCCGCGCTGGTGGATCAGGTGCCATTCCTGTTTGTCGCCCACGACGTCGGGCCGCGTGCGATTTCCCCTG
CGGTGACCGGGGTGGTGCAACCGCAGAGCTGGTTTATCGACCTCAGCCTGGTGAGCAAAAAAGAGTAA

Upstream 100 bases:

>100_bases
CTTATTTTACCGGTCGGTTTTGACCTATTTTCGTCCGCGTAAGAGCTGGTACGCATTTTGCCTGTTAATCCGTGACATTT
TATTTAACAGGGATCATGTG

Downstream 100 bases:

>100_bases
TCGCGAAAGGGGCGACCGATGATCAATACGCTGCTATACCGCATTCTGCTGGCTATCCCCACCATGCTGGGGGTGGCGGT
GATCTGTTTCATGCTGGTGC

Product: extracellular solute-binding family protein 5

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MHKKTLFSRAGRLAVAVSGALALAGAALPANASTLRIAMTAADIPLTLGQPDQGYEGNRFTGIPLYDALVEWDLSQGEKP
SGLVPGLATEWHIDPQNTSRWIFTLRPGVKFHDGTEVNADAIVWNVDKVLNKAAPQYAPGQIGNTLSRMPTLTGAEKIDD
HTVALTTSEPDALLPYNITNLFIVSPTAWQKQYDAVPASVGDSAARSKQAWTAFAAHAVGSGPFKLEKLVPRQQLILDKN
PDYWNKDRIPRVDKVVLIPLPEANARTAALLSKQVDWIEAPAPDAIDQIKSQGFHLYANTQPHLWPWQFSFEKGSPWQDI
RVRKAANLCLNRAELKSYLGGYMTEATGVYEADSPWHGKPTFQIKYDPDVARQLMTEAGYSASKPLHVTVATSASGSGQM
QPLPMNEYIQQSLKSCFFNVDIKVVEWNTLFTNWRLGARDPSAKGIDAINVSAAVNDPYFGLIRFSTAKAFPPVATNWGY
FSTPETEKLAAAVKHAFTPAEMNKAAGELHAALVDQVPFLFVAHDVGPRAISPAVTGVVQPQSWFIDLSLVSKKE

Sequences:

>Translated_555_residues
MHKKTLFSRAGRLAVAVSGALALAGAALPANASTLRIAMTAADIPLTLGQPDQGYEGNRFTGIPLYDALVEWDLSQGEKP
SGLVPGLATEWHIDPQNTSRWIFTLRPGVKFHDGTEVNADAIVWNVDKVLNKAAPQYAPGQIGNTLSRMPTLTGAEKIDD
HTVALTTSEPDALLPYNITNLFIVSPTAWQKQYDAVPASVGDSAARSKQAWTAFAAHAVGSGPFKLEKLVPRQQLILDKN
PDYWNKDRIPRVDKVVLIPLPEANARTAALLSKQVDWIEAPAPDAIDQIKSQGFHLYANTQPHLWPWQFSFEKGSPWQDI
RVRKAANLCLNRAELKSYLGGYMTEATGVYEADSPWHGKPTFQIKYDPDVARQLMTEAGYSASKPLHVTVATSASGSGQM
QPLPMNEYIQQSLKSCFFNVDIKVVEWNTLFTNWRLGARDPSAKGIDAINVSAAVNDPYFGLIRFSTAKAFPPVATNWGY
FSTPETEKLAAAVKHAFTPAEMNKAAGELHAALVDQVPFLFVAHDVGPRAISPAVTGVVQPQSWFIDLSLVSKKE
>Mature_555_residues
MHKKTLFSRAGRLAVAVSGALALAGAALPANASTLRIAMTAADIPLTLGQPDQGYEGNRFTGIPLYDALVEWDLSQGEKP
SGLVPGLATEWHIDPQNTSRWIFTLRPGVKFHDGTEVNADAIVWNVDKVLNKAAPQYAPGQIGNTLSRMPTLTGAEKIDD
HTVALTTSEPDALLPYNITNLFIVSPTAWQKQYDAVPASVGDSAARSKQAWTAFAAHAVGSGPFKLEKLVPRQQLILDKN
PDYWNKDRIPRVDKVVLIPLPEANARTAALLSKQVDWIEAPAPDAIDQIKSQGFHLYANTQPHLWPWQFSFEKGSPWQDI
RVRKAANLCLNRAELKSYLGGYMTEATGVYEADSPWHGKPTFQIKYDPDVARQLMTEAGYSASKPLHVTVATSASGSGQM
QPLPMNEYIQQSLKSCFFNVDIKVVEWNTLFTNWRLGARDPSAKGIDAINVSAAVNDPYFGLIRFSTAKAFPPVATNWGY
FSTPETEKLAAAVKHAFTPAEMNKAAGELHAALVDQVPFLFVAHDVGPRAISPAVTGVVQPQSWFIDLSLVSKKE

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=548, Percent_Identity=22.8102189781022, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1787495, Length=469, Percent_Identity=24.9466950959488, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87081878, Length=501, Percent_Identity=24.750499001996, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787052, Length=514, Percent_Identity=24.5136186770428, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787762, Length=297, Percent_Identity=28.6195286195286, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60636; Mature: 60636

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKKTLFSRAGRLAVAVSGALALAGAALPANASTLRIAMTAADIPLTLGQPDQGYEGNRF
CCCHHHHHHCCCEEEEECCHHHHHCCCCCCCCCEEEEEEEECCCEEECCCCCCCCCCCEE
TGIPLYDALVEWDLSQGEKPSGLVPGLATEWHIDPQNTSRWIFTLRPGVKFHDGTEVNAD
ECCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCEECCCCCCCCC
AIVWNVDKVLNKAAPQYAPGQIGNTLSRMPTLTGAEKIDDHTVALTTSEPDALLPYNITN
EEEEEHHHHHHHCCCCCCCCHHCCHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCE
LFIVSPTAWQKQYDAVPASVGDSAARSKQAWTAFAAHAVGSGPFKLEKLVPRQQLILDKN
EEEECCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHEEECCC
PDYWNKDRIPRVDKVVLIPLPEANARTAALLSKQVDWIEAPAPDAIDQIKSQGFHLYANT
CCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHCCCCCHHHHHHHHCCEEEEECC
QPHLWPWQFSFEKGSPWQDIRVRKAANLCLNRAELKSYLGGYMTEATGVYEADSPWHGKP
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEECCCCCCCCC
TFQIKYDPDVARQLMTEAGYSASKPLHVTVATSASGSGQMQPLPMNEYIQQSLKSCFFNV
EEEEEECHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEEC
DIKVVEWNTLFTNWRLGARDPSAKGIDAINVSAAVNDPYFGLIRFSTAKAFPPVATNWGY
EEEEEEEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCCCCCCC
FSTPETEKLAAAVKHAFTPAEMNKAAGELHAALVDQVPFLFVAHDVGPRAISPAVTGVVQ
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHEEEC
PQSWFIDLSLVSKKE
CCCEEEEEEEECCCC
>Mature Secondary Structure
MHKKTLFSRAGRLAVAVSGALALAGAALPANASTLRIAMTAADIPLTLGQPDQGYEGNRF
CCCHHHHHHCCCEEEEECCHHHHHCCCCCCCCCEEEEEEEECCCEEECCCCCCCCCCCEE
TGIPLYDALVEWDLSQGEKPSGLVPGLATEWHIDPQNTSRWIFTLRPGVKFHDGTEVNAD
ECCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCEECCCCCCCCC
AIVWNVDKVLNKAAPQYAPGQIGNTLSRMPTLTGAEKIDDHTVALTTSEPDALLPYNITN
EEEEEHHHHHHHCCCCCCCCHHCCHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCE
LFIVSPTAWQKQYDAVPASVGDSAARSKQAWTAFAAHAVGSGPFKLEKLVPRQQLILDKN
EEEECCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHEEECCC
PDYWNKDRIPRVDKVVLIPLPEANARTAALLSKQVDWIEAPAPDAIDQIKSQGFHLYANT
CCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHCCCCCHHHHHHHHCCEEEEECC
QPHLWPWQFSFEKGSPWQDIRVRKAANLCLNRAELKSYLGGYMTEATGVYEADSPWHGKP
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEECCCCCCCCC
TFQIKYDPDVARQLMTEAGYSASKPLHVTVATSASGSGQMQPLPMNEYIQQSLKSCFFNV
EEEEEECHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEEC
DIKVVEWNTLFTNWRLGARDPSAKGIDAINVSAAVNDPYFGLIRFSTAKAFPPVATNWGY
EEEEEEEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCCCCCCC
FSTPETEKLAAAVKHAFTPAEMNKAAGELHAALVDQVPFLFVAHDVGPRAISPAVTGVVQ
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHEEEC
PQSWFIDLSLVSKKE
CCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]