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The map label for this gene is cadC [H]

Identifier: 152969069

GI number: 152969069

Start: 544775

End: 546343

Strand: Direct

Name: cadC [H]

Synonym: KPN_00498

Alternate gene names: 152969069

Gene position: 544775-546343 (Clockwise)

Preceding gene: 152969068

Following gene: 152969070

Centisome position: 10.25

GC content: 55.64

Gene sequence:

>1569_bases
ATGCTACAACCTGTTGTTCGCGTCGGTGAATGGCTGGTAACCCCCTCTGTAAACCAAATCAGCAGGAAGGGGCGCCAGCT
TACCCTTGAACCGCGTTTAATCGATCTTCTGGTCTTTTTTGCCCGCCATCCGGGGGAAGTGCTTAGCCGGGACGAGCTTA
TCGAAAACGTCTGGACCCGGAACGTTGTGACCAGCCACGTCGTCACGCAGAGTATTTCTGAACTGCGCAAGTCGCTCAAA
GACGGCGACGACGTTAGCCTTGAGTACATCGCGACGGTACCCAAACGGGGGTATAAGCTCACGGTGCCGGTGATCTGGTG
CACCGAAGAGGGGGAGGAGCTAGCCCCGTCGATGGAGGCGCTGACGCCTTCGCCGTCGACCGCCGTTCCTGCGCCGCCGG
CCGCCGGTGCGCCATCCGACGTCTCTGTCCCTCTCCCTGATGCCGCCGCGCCGCCACCGGCTCCTACCGTGGCCAGCGCG
CCGTCAGGCCGCAAGCGCCTCACTACCGCCCTGGTGTGGGGGCTGTTCCTGTTGGCGCTGGGCACCTGCGTGGCGCTGGT
GGCGCTGTCGAGCATGGAATCGCGGCCGCCGGTCAACAAGGCGCGTCTGCTGCTCAATCCGCGTGATATCGATATCCACC
TGGTGAATGGCAACTCCTGCGCTAACTGGTCGTCGCAGCACTCCTACGCCGTAGGACTGGCCAGCCTGATCACCACCTCG
CTGAACACCTTCTCGACCTTTATGGTGCATGATAAAACGGACTACAACATCAATGAACCAAGCAGTTCCGGCAAAACGCT
GACCATCGAGTTCGTTAATCAGCGCCATTATCGGGCGCAGCAGTGCTTTATGTCGGTCCAGCTGGTGGACAACGCCGACA
GCTCGACGATGCTGGATAAGCGCTACTTTGTGACCAACGATAACCAGCTGACCATCCAGAACGATCTGATGAACAGCCTG
TCGGATGCCCTGGCGCAGCCGTGGCCGGCGCGAATGCAGGCGATGCTCAGGCAATATCAGCCCTCGCAAAGCGTGGCGTT
AACCTATTTCTACCAGTCGCATCAGCTGTTAATGAAGGGCGACGTCGATTCATTAAGTAAGGCCAGTAGCCTGCTGGATG
ATGTGATTAAGCGGGCGCCGGATTTTATTTACGCCTATGCCGAAAAAACGCTGGTGGATGTATTGCGCCATTCACAACAG
CCGCTTGACGATAAACAGCTGGCCGCCCTCTACAGTGAAGTCGAGCGGGTAGGGGCGATGCCGGGTATAAAAGACATGGC
GATTTATTATCAAATAAAAGCGGTGGATTCATTGGGGAAGGGCAAAGTCGACGAAGCAAATACCGCAATTAATAGTGCGA
TTGATTTAGAGATGTCATGGCTAAATTATGTGCTGTTAGGCAAAGTCTATGAGATGAAAGGTGAGAACCGTCTGGCTGCC
GATTCTTACATCACGGCGTTTAATTTACGTCCTGGCGAAGATACCCTGTACTGGATTGAAAATGGGGTTTTCCAGACGTC
GGTTAACCGAGTAGTTCCATATCTCGACAACTTTCTCTCTTCAGAATAA

Upstream 100 bases:

>100_bases
CAATTCCGGCCTAATGCCTGAGGGAGTGACCCCTGGCAAAAATAGGTAGGACAAATGTGTTATCATCGCGCCTTTCCCTT
TTTGTCTGGGGCTTTCTTGT

Downstream 100 bases:

>100_bases
GTAAACCCTCATCATGTGCAAGGTTTTGGGCATGGTGAGGTTAAATTTATGTTTCTCATGAAGCCTCTTGTTGTTATTTT
TATTTAGCATTCAGGAGGCT

Product: DNA-binding transcriptional activator CadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MLQPVVRVGEWLVTPSVNQISRKGRQLTLEPRLIDLLVFFARHPGEVLSRDELIENVWTRNVVTSHVVTQSISELRKSLK
DGDDVSLEYIATVPKRGYKLTVPVIWCTEEGEELAPSMEALTPSPSTAVPAPPAAGAPSDVSVPLPDAAAPPPAPTVASA
PSGRKRLTTALVWGLFLLALGTCVALVALSSMESRPPVNKARLLLNPRDIDIHLVNGNSCANWSSQHSYAVGLASLITTS
LNTFSTFMVHDKTDYNINEPSSSGKTLTIEFVNQRHYRAQQCFMSVQLVDNADSSTMLDKRYFVTNDNQLTIQNDLMNSL
SDALAQPWPARMQAMLRQYQPSQSVALTYFYQSHQLLMKGDVDSLSKASSLLDDVIKRAPDFIYAYAEKTLVDVLRHSQQ
PLDDKQLAALYSEVERVGAMPGIKDMAIYYQIKAVDSLGKGKVDEANTAINSAIDLEMSWLNYVLLGKVYEMKGENRLAA
DSYITAFNLRPGEDTLYWIENGVFQTSVNRVVPYLDNFLSSE

Sequences:

>Translated_522_residues
MLQPVVRVGEWLVTPSVNQISRKGRQLTLEPRLIDLLVFFARHPGEVLSRDELIENVWTRNVVTSHVVTQSISELRKSLK
DGDDVSLEYIATVPKRGYKLTVPVIWCTEEGEELAPSMEALTPSPSTAVPAPPAAGAPSDVSVPLPDAAAPPPAPTVASA
PSGRKRLTTALVWGLFLLALGTCVALVALSSMESRPPVNKARLLLNPRDIDIHLVNGNSCANWSSQHSYAVGLASLITTS
LNTFSTFMVHDKTDYNINEPSSSGKTLTIEFVNQRHYRAQQCFMSVQLVDNADSSTMLDKRYFVTNDNQLTIQNDLMNSL
SDALAQPWPARMQAMLRQYQPSQSVALTYFYQSHQLLMKGDVDSLSKASSLLDDVIKRAPDFIYAYAEKTLVDVLRHSQQ
PLDDKQLAALYSEVERVGAMPGIKDMAIYYQIKAVDSLGKGKVDEANTAINSAIDLEMSWLNYVLLGKVYEMKGENRLAA
DSYITAFNLRPGEDTLYWIENGVFQTSVNRVVPYLDNFLSSE
>Mature_522_residues
MLQPVVRVGEWLVTPSVNQISRKGRQLTLEPRLIDLLVFFARHPGEVLSRDELIENVWTRNVVTSHVVTQSISELRKSLK
DGDDVSLEYIATVPKRGYKLTVPVIWCTEEGEELAPSMEALTPSPSTAVPAPPAAGAPSDVSVPLPDAAAPPPAPTVASA
PSGRKRLTTALVWGLFLLALGTCVALVALSSMESRPPVNKARLLLNPRDIDIHLVNGNSCANWSSQHSYAVGLASLITTS
LNTFSTFMVHDKTDYNINEPSSSGKTLTIEFVNQRHYRAQQCFMSVQLVDNADSSTMLDKRYFVTNDNQLTIQNDLMNSL
SDALAQPWPARMQAMLRQYQPSQSVALTYFYQSHQLLMKGDVDSLSKASSLLDDVIKRAPDFIYAYAEKTLVDVLRHSQQ
PLDDKQLAALYSEVERVGAMPGIKDMAIYYQIKAVDSLGKGKVDEANTAINSAIDLEMSWLNYVLLGKVYEMKGENRLAA
DSYITAFNLRPGEDTLYWIENGVFQTSVNRVVPYLDNFLSSE

Specific function: Required for Pcad induction, a promoter upstream of cadB that is responsible for the pH-regulated expression of cadA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790576, Length=525, Percent_Identity=65.9047619047619, Blast_Score=678, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011990
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 57762; Mature: 57762

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQPVVRVGEWLVTPSVNQISRKGRQLTLEPRLIDLLVFFARHPGEVLSRDELIENVWTR
CCCCHHHHCCEEECCCHHHHHHCCCEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
NVVTSHVVTQSISELRKSLKDGDDVSLEYIATVPKRGYKLTVPVIWCTEEGEELAPSMEA
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEEEECCCCHHHCCCHHH
LTPSPSTAVPAPPAAGAPSDVSVPLPDAAAPPPAPTVASAPSGRKRLTTALVWGLFLLAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GTCVALVALSSMESRPPVNKARLLLNPRDIDIHLVNGNSCANWSSQHSYAVGLASLITTS
HHHHHHHHHHHHCCCCCCCHHEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
LNTFSTFMVHDKTDYNINEPSSSGKTLTIEFVNQRHYRAQQCFMSVQLVDNADSSTMLDK
HHHHEEEEEECCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHEEEEEECCCCCCCEECC
RYFVTNDNQLTIQNDLMNSLSDALAQPWPARMQAMLRQYQPSQSVALTYFYQSHQLLMKG
EEEEECCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEC
DVDSLSKASSLLDDVIKRAPDFIYAYAEKTLVDVLRHSQQPLDDKQLAALYSEVERVGAM
CHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
PGIKDMAIYYQIKAVDSLGKGKVDEANTAINSAIDLEMSWLNYVLLGKVYEMKGENRLAA
CCCCCEEEEEEEEEHHCCCCCCCCHHHHHHHHHHEEEHHHHHHHHHHHHHHHCCCCCEEC
DSYITAFNLRPGEDTLYWIENGVFQTSVNRVVPYLDNFLSSE
CCEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLQPVVRVGEWLVTPSVNQISRKGRQLTLEPRLIDLLVFFARHPGEVLSRDELIENVWTR
CCCCHHHHCCEEECCCHHHHHHCCCEEEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
NVVTSHVVTQSISELRKSLKDGDDVSLEYIATVPKRGYKLTVPVIWCTEEGEELAPSMEA
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEEEECCCCHHHCCCHHH
LTPSPSTAVPAPPAAGAPSDVSVPLPDAAAPPPAPTVASAPSGRKRLTTALVWGLFLLAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GTCVALVALSSMESRPPVNKARLLLNPRDIDIHLVNGNSCANWSSQHSYAVGLASLITTS
HHHHHHHHHHHHCCCCCCCHHEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
LNTFSTFMVHDKTDYNINEPSSSGKTLTIEFVNQRHYRAQQCFMSVQLVDNADSSTMLDK
HHHHEEEEEECCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHEEEEEECCCCCCCEECC
RYFVTNDNQLTIQNDLMNSLSDALAQPWPARMQAMLRQYQPSQSVALTYFYQSHQLLMKG
EEEEECCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEC
DVDSLSKASSLLDDVIKRAPDFIYAYAEKTLVDVLRHSQQPLDDKQLAALYSEVERVGAM
CHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
PGIKDMAIYYQIKAVDSLGKGKVDEANTAINSAIDLEMSWLNYVLLGKVYEMKGENRLAA
CCCCCEEEEEEEEEHHCCCCCCCCHHHHHHHHHHEEEHHHHHHHHHHHHHHHCCCCCEEC
DSYITAFNLRPGEDTLYWIENGVFQTSVNRVVPYLDNFLSSE
CCEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370290; 7610040; 9278503 [H]