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The map label for this gene is mocR [H]

Identifier: 152969011

GI number: 152969011

Start: 480901

End: 482352

Strand: Direct

Name: mocR [H]

Synonym: KPN_00438

Alternate gene names: 152969011

Gene position: 480901-482352 (Clockwise)

Preceding gene: 152969009

Following gene: 152969018

Centisome position: 9.05

GC content: 64.12

Gene sequence:

>1452_bases
ATGAATATACCGGACGAGGGGTTTTTTACGCTGTTGACGCAGGGGATGCGGAACCGCACGGTCGAAACCTTACAGCGCGC
CCTTTACCACACCTTACGTGACGCTATCCTGCAGGGAACCCTGACGGCCCGCTGCCGTTTACCCGGATCGCGGGTGATGG
CCGAACGGCTACACCTGTCGCGGAATACGGTCAATGCCGCACTGGAACAGCTGGCGCTGGAGGGGTACCTGACACGGAGC
CGTCAGGGAACGCAGGTGGCACCACTCGCCTCCTGCCGCCAGGAGGCGGGTCAGATGCCGCCCGTCGTGCTGCCTGAGCG
GCTGCAAAGGCTGCCAGCCGCGATGCGCCGCGACTCACCGACGCTGGCATTTACGCCAGGCATGCCGGCGGTAAACTATT
TCCCGCTGCCGCTGTGGCGGCGACTGATGGATAACGTGCTACGCGAAGATGGTAGCGCGCTGCTGGGTTATGGCGAAGCC
GCGGGCGATCCTTTGCTGCGAGAGGCTATCGCTCGTCATCTGGCGCTCTCCCGGGGCATCCGGTGCGATATCCGGCAGAT
CGTCATCACCGAAGGCGCGCTGGAAGGCGTCAACTTATGCGCCTCGCTACTGACCAACCCGGGCGACAGCGTGTGGCTGG
AAGAACCGGGGTACCTGGGGGCGTGGAGTGGCTTTCAGCGGGCGGGACTGCGGGTCAGAGGAATGGCTGTCGACGATGAA
GGGATGTGTATTGCCAACGGCGTCGCGGAGCCGCCCCGGCTCATTTTCACCTCTCCTTCACACCAGTATCCCTGTGGGAG
CATCATGAGCGCCGGGCGCCGTCTGGCGCTCGTGGAATATGCCCGCCGGCACGGGGCGTGGATTGTGGAGGATGACTACG
ACAGCGAGTTTCGCCATAGCGGAGAACCGATCCCGGCGATGCTGGGAATGGTGCCTGATGCCCCGGTGGTCTATCTCGGC
ACCTTCAGCAAAACGCTGTTTCCGGCGTTGCGTATCGGTTTTATGGTTATGCCGCCCGCGCTGGCGGATGCTGCTCAGGA
CGCCATTGGCGCGCTGCTGCGCGGGGGACACCGTGCTGAACAGCGGGCGCTGGCCAGCTTTATCGAGAAGGGACACTATG
CGCGCCATCTGGCGGCGATGCGCCGCCTGTACCGTAAACGTCAGCAACAGCTGCGCGAGGCGCTGGCGCAAGAGATAACC
GTGCCGTGCGACGTTCTCGGCGGGGGAGGGGGGATGCACCTGACGGTGGCGATGGAGGGCGTTAATGACCGGACGCTTGC
GCAGCAGGCGCGCCAGTTTCAGCTGGCGCCCGCCGCGTTAAGTCATTTCTATCTCGACCCGCAGCGAGCGCGGAGCGGAC
TGGTGCTTGGGTATGGCAATACCTCTGCTTCTCGCTATCTCCCGGCGCTGCGGACCCTAAATCGCCTTATTGCGCAGCAC
CGGCGCGCGTGA

Upstream 100 bases:

>100_bases
TGCGGTTTCCTTATTGGAGATTTACAGGCAGCGTACGCGCTCGCTGGTTCCATAAAAAGTGCCATTAGAGTATGTTTTTA
TGGGGCCACGAGGAGGCAAT

Downstream 100 bases:

>100_bases
GGGTAAAGACATCGTAGAAGGAGAGCTCGCCTTTGGTGGCGACCATCTTTTTGAGCTGCGCCTTCTGCTCGCTATCGACG
TCTGGCGACTGCAGGATACG

Product: GntR transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MNIPDEGFFTLLTQGMRNRTVETLQRALYHTLRDAILQGTLTARCRLPGSRVMAERLHLSRNTVNAALEQLALEGYLTRS
RQGTQVAPLASCRQEAGQMPPVVLPERLQRLPAAMRRDSPTLAFTPGMPAVNYFPLPLWRRLMDNVLREDGSALLGYGEA
AGDPLLREAIARHLALSRGIRCDIRQIVITEGALEGVNLCASLLTNPGDSVWLEEPGYLGAWSGFQRAGLRVRGMAVDDE
GMCIANGVAEPPRLIFTSPSHQYPCGSIMSAGRRLALVEYARRHGAWIVEDDYDSEFRHSGEPIPAMLGMVPDAPVVYLG
TFSKTLFPALRIGFMVMPPALADAAQDAIGALLRGGHRAEQRALASFIEKGHYARHLAAMRRLYRKRQQQLREALAQEIT
VPCDVLGGGGGMHLTVAMEGVNDRTLAQQARQFQLAPAALSHFYLDPQRARSGLVLGYGNTSASRYLPALRTLNRLIAQH
RRA

Sequences:

>Translated_483_residues
MNIPDEGFFTLLTQGMRNRTVETLQRALYHTLRDAILQGTLTARCRLPGSRVMAERLHLSRNTVNAALEQLALEGYLTRS
RQGTQVAPLASCRQEAGQMPPVVLPERLQRLPAAMRRDSPTLAFTPGMPAVNYFPLPLWRRLMDNVLREDGSALLGYGEA
AGDPLLREAIARHLALSRGIRCDIRQIVITEGALEGVNLCASLLTNPGDSVWLEEPGYLGAWSGFQRAGLRVRGMAVDDE
GMCIANGVAEPPRLIFTSPSHQYPCGSIMSAGRRLALVEYARRHGAWIVEDDYDSEFRHSGEPIPAMLGMVPDAPVVYLG
TFSKTLFPALRIGFMVMPPALADAAQDAIGALLRGGHRAEQRALASFIEKGHYARHLAAMRRLYRKRQQQLREALAQEIT
VPCDVLGGGGGMHLTVAMEGVNDRTLAQQARQFQLAPAALSHFYLDPQRARSGLVLGYGNTSASRYLPALRTLNRLIAQH
RRA
>Mature_483_residues
MNIPDEGFFTLLTQGMRNRTVETLQRALYHTLRDAILQGTLTARCRLPGSRVMAERLHLSRNTVNAALEQLALEGYLTRS
RQGTQVAPLASCRQEAGQMPPVVLPERLQRLPAAMRRDSPTLAFTPGMPAVNYFPLPLWRRLMDNVLREDGSALLGYGEA
AGDPLLREAIARHLALSRGIRCDIRQIVITEGALEGVNLCASLLTNPGDSVWLEEPGYLGAWSGFQRAGLRVRGMAVDDE
GMCIANGVAEPPRLIFTSPSHQYPCGSIMSAGRRLALVEYARRHGAWIVEDDYDSEFRHSGEPIPAMLGMVPDAPVVYLG
TFSKTLFPALRIGFMVMPPALADAAQDAIGALLRGGHRAEQRALASFIEKGHYARHLAAMRRLYRKRQQQLREALAQEIT
VPCDVLGGGGGMHLTVAMEGVNDRTLAQQARQFQLAPAALSHFYLDPQRARSGLVLGYGNTSASRYLPALRTLNRLIAQH
RRA

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=314, Percent_Identity=22.6114649681529, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI33469970, Length=314, Percent_Identity=22.6114649681529, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1790797, Length=434, Percent_Identity=29.0322580645161, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1787710, Length=408, Percent_Identity=27.6960784313726, Blast_Score=108, Evalue=9e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53156; Mature: 53156

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50949 HTH_GNTR ; PS00527 RIBOSOMAL_S14

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIPDEGFFTLLTQGMRNRTVETLQRALYHTLRDAILQGTLTARCRLPGSRVMAERLHLS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCHHHHHHHHHHHH
RNTVNAALEQLALEGYLTRSRQGTQVAPLASCRQEAGQMPPVVLPERLQRLPAAMRRDSP
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
TLAFTPGMPAVNYFPLPLWRRLMDNVLREDGSALLGYGEAAGDPLLREAIARHLALSRGI
CEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCC
RCDIRQIVITEGALEGVNLCASLLTNPGDSVWLEEPGYLGAWSGFQRAGLRVRGMAVDDE
CCCHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHCCCEEEEEEECCC
GMCIANGVAEPPRLIFTSPSHQYPCGSIMSAGRRLALVEYARRHGAWIVEDDYDSEFRHS
CCEEECCCCCCCEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHCCCEEEECCCCCHHHHC
GEPIPAMLGMVPDAPVVYLGTFSKTLFPALRIGFMVMPPALADAAQDAIGALLRGGHRAE
CCCHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHH
QRALASFIEKGHYARHLAAMRRLYRKRQQQLREALAQEITVPCDVLGGGGGMHLTVAMEG
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECC
VNDRTLAQQARQFQLAPAALSHFYLDPQRARSGLVLGYGNTSASRYLPALRTLNRLIAQH
CCHHHHHHHHHHHHCCHHHHHHHCCCHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
RRA
CCC
>Mature Secondary Structure
MNIPDEGFFTLLTQGMRNRTVETLQRALYHTLRDAILQGTLTARCRLPGSRVMAERLHLS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCHHHHHHHHHHHH
RNTVNAALEQLALEGYLTRSRQGTQVAPLASCRQEAGQMPPVVLPERLQRLPAAMRRDSP
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
TLAFTPGMPAVNYFPLPLWRRLMDNVLREDGSALLGYGEAAGDPLLREAIARHLALSRGI
CEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCC
RCDIRQIVITEGALEGVNLCASLLTNPGDSVWLEEPGYLGAWSGFQRAGLRVRGMAVDDE
CCCHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHCCCEEEEEEECCC
GMCIANGVAEPPRLIFTSPSHQYPCGSIMSAGRRLALVEYARRHGAWIVEDDYDSEFRHS
CCEEECCCCCCCEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHCCCEEEECCCCCHHHHC
GEPIPAMLGMVPDAPVVYLGTFSKTLFPALRIGFMVMPPALADAAQDAIGALLRGGHRAE
CCCHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHH
QRALASFIEKGHYARHLAAMRRLYRKRQQQLREALAQEITVPCDVLGGGGGMHLTVAMEG
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECC
VNDRTLAQQARQFQLAPAALSHFYLDPQRARSGLVLGYGNTSASRYLPALRTLNRLIAQH
CCHHHHHHHHHHHHCCHHHHHHHCCCHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
RRA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]