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The map label for this gene is malZ [H]

Identifier: 152968917

GI number: 152968917

Start: 385411

End: 387228

Strand: Direct

Name: malZ [H]

Synonym: KPN_00344

Alternate gene names: 152968917

Gene position: 385411-387228 (Clockwise)

Preceding gene: 152968916

Following gene: 152968919

Centisome position: 7.25

GC content: 62.76

Gene sequence:

>1818_bases
ATGTTGAAGGCATGGCACCTTCCGGTTGCACCCTTTATCAAGGTGCAACAGGACCGACTGTTTATTACTCTGTGGTTAAG
CGGTGAGTCGCTGCCGCAGCGGATCACGCTGCGCGCGGAAGAGGATAACGAAGAGCTGTCGCTGCCGATGCAGCGGCTCC
GCCAGGCGCCACAGCCAGGCGTGGTGGCATGGCGCGGCGAAATCTCTCTCGCCAGCGGCCAGCCGCGCCGCCGCTACAGC
TTTAAGCTGCTGTGGGCCGACCATCAGCGCTGGTTTACGCCACAAGGCTTCACCCGATTCCCGCCGGCCAGACTGGAGCA
GTTCGCCATTGACCTGCCGGACGCCGGCCCGCAGTGGGTGGCCGATCAGGTGTTCTATCAAATTTTCCCCGATCGCTTTG
CCCGCAGCGCCGCGCGTGACGCCGACCAGGATGCGGTCTATTACCATCACGCGGCGGGACGGGAGATTGTGCGCAAGGCG
TGGGACGACCCGCTTACCGGCGAGGCGGGCGGGTCGACGTTCTACGGCGGGGATCTCGACGGCATCAGCGAAAAACTTCC
CTACCTGAAGCAGCTCGGCGTAACCGCTCTGTATCTGAACCCGGTTTTCGCCGCCCCCAGCGTGCATAAATACGATACCG
AGGATTATCGGCGCGTCGATCCGCAGTTTGGCGGCGACGCGGCGCTGCTCCGGCTGCGCCACAACACCCAGCGGGCGGGA
ATGCGCATGATCCTCGACGGCGTGTTCAACCATACCGGCGATTCCCATCCCTGGTTCGACCGTCACCAGCAGGGCAGCGG
CGGCGCCGGCCACGATCCGGACTCCCCGTGGCGCGACTGGTTTACCTTCTCAGAGGAGGGGCAGGCGCACAACTGGCTGG
GTTATGCCAGTCTGCCGAAGCTCGACTATCGGTCGACCAGCCTGGTCAACGAGATCTATGCCGGTGAAGACAGTATCGTA
CGCCACTGGCTGAAGGCGCCATGGAGCATGGACGGCTGGCGTCTGGACGTGGTGCATATGCTGGGCGAAGGCGGCGGGGC
GCGGAATAACCTGCAGCATATCGCCGGCATTACCCAGGCGGCGAAGCAAGCGCAGCCGGAAGCTTTTGTCTTTGGCGAAC
ATTTTGGCGACGCGCGCCAGTGGCTGCAGGCGGATGCCGAAGACGCGGCGATGAACTATCGCGGCTTCACCTTCCCGATC
TGGGGATTCCTCGCCAATACCGATATTTCTTACGATCCGCAGAAAATAGACGCCCAGACCTGTATGGCGTGGATGGATAA
TTATCGCGCCGGGCTGTCGCATCAGCAGCAGCTGCGGATGTTCAACCAGCTCGACAGCCATGATACGGCGCGTTTTAAAT
CTCTTCTTGGCAAAGACGTAGCGCGCTTGCCGCTGGCGGTGGTGTGGCTGTTCAGCTGGCCGGGGGTACCGTGCATCTAC
TATGGCGACGAGGTGGGCGTGGATGGCAATAACGATCCGTTCTGCCGCAAACCGTTCCCGTGGGATCCGGCGCTGCAGGA
TACCCAGCTGCTGGCGCTGTATCAGCGGATGGCGAAACTGCGTAAGGCCCACCAGGCGCTGCGCTATGGCGGCTGTCAGG
TGATTTACGCCGAGGATAACGTGGTGGTGTTTGTCCGCGTCTACAAACAGCAGCGGGTGCTGGTGGCGATTAACCGCGGG
GAAGCCTGCGAGGTGGTTATCGAAGATTCCCCGCTGCTGAACGTGGCCGGGTGGACGCTGCAGGAGGGCGCCGGCGCCTT
CCAGGACGGGGTGCTGACCCTCCCGGCCATCTCCGCCAACGTCTGGTCCGGCCGTTAA

Upstream 100 bases:

>100_bases
GTCCTCCCCCGTTATCCTCCCCCAAAAAGTTCTGAGATGATGAGTTCTGCGCCCGGCGGCTATGGCAAGGTGTGCCCATT
CTGCACAATGAGGATTCACG

Downstream 100 bases:

>100_bases
TGGTAGAGCTGGCTCAGCAGGTCGCCGCGGAGGAGCGCCTCCCGCCACCAGCGCTGAGCCAGCCCATCATTCCCGCTGCG
CCAGGCCATATAGGTAATAT

Product: maltodextrin glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase [H]

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MLKAWHLPVAPFIKVQQDRLFITLWLSGESLPQRITLRAEEDNEELSLPMQRLRQAPQPGVVAWRGEISLASGQPRRRYS
FKLLWADHQRWFTPQGFTRFPPARLEQFAIDLPDAGPQWVADQVFYQIFPDRFARSAARDADQDAVYYHHAAGREIVRKA
WDDPLTGEAGGSTFYGGDLDGISEKLPYLKQLGVTALYLNPVFAAPSVHKYDTEDYRRVDPQFGGDAALLRLRHNTQRAG
MRMILDGVFNHTGDSHPWFDRHQQGSGGAGHDPDSPWRDWFTFSEEGQAHNWLGYASLPKLDYRSTSLVNEIYAGEDSIV
RHWLKAPWSMDGWRLDVVHMLGEGGGARNNLQHIAGITQAAKQAQPEAFVFGEHFGDARQWLQADAEDAAMNYRGFTFPI
WGFLANTDISYDPQKIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKSLLGKDVARLPLAVVWLFSWPGVPCIY
YGDEVGVDGNNDPFCRKPFPWDPALQDTQLLALYQRMAKLRKAHQALRYGGCQVIYAEDNVVVFVRVYKQQRVLVAINRG
EACEVVIEDSPLLNVAGWTLQEGAGAFQDGVLTLPAISANVWSGR

Sequences:

>Translated_605_residues
MLKAWHLPVAPFIKVQQDRLFITLWLSGESLPQRITLRAEEDNEELSLPMQRLRQAPQPGVVAWRGEISLASGQPRRRYS
FKLLWADHQRWFTPQGFTRFPPARLEQFAIDLPDAGPQWVADQVFYQIFPDRFARSAARDADQDAVYYHHAAGREIVRKA
WDDPLTGEAGGSTFYGGDLDGISEKLPYLKQLGVTALYLNPVFAAPSVHKYDTEDYRRVDPQFGGDAALLRLRHNTQRAG
MRMILDGVFNHTGDSHPWFDRHQQGSGGAGHDPDSPWRDWFTFSEEGQAHNWLGYASLPKLDYRSTSLVNEIYAGEDSIV
RHWLKAPWSMDGWRLDVVHMLGEGGGARNNLQHIAGITQAAKQAQPEAFVFGEHFGDARQWLQADAEDAAMNYRGFTFPI
WGFLANTDISYDPQKIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKSLLGKDVARLPLAVVWLFSWPGVPCIY
YGDEVGVDGNNDPFCRKPFPWDPALQDTQLLALYQRMAKLRKAHQALRYGGCQVIYAEDNVVVFVRVYKQQRVLVAINRG
EACEVVIEDSPLLNVAGWTLQEGAGAFQDGVLTLPAISANVWSGR
>Mature_605_residues
MLKAWHLPVAPFIKVQQDRLFITLWLSGESLPQRITLRAEEDNEELSLPMQRLRQAPQPGVVAWRGEISLASGQPRRRYS
FKLLWADHQRWFTPQGFTRFPPARLEQFAIDLPDAGPQWVADQVFYQIFPDRFARSAARDADQDAVYYHHAAGREIVRKA
WDDPLTGEAGGSTFYGGDLDGISEKLPYLKQLGVTALYLNPVFAAPSVHKYDTEDYRRVDPQFGGDAALLRLRHNTQRAG
MRMILDGVFNHTGDSHPWFDRHQQGSGGAGHDPDSPWRDWFTFSEEGQAHNWLGYASLPKLDYRSTSLVNEIYAGEDSIV
RHWLKAPWSMDGWRLDVVHMLGEGGGARNNLQHIAGITQAAKQAQPEAFVFGEHFGDARQWLQADAEDAAMNYRGFTFPI
WGFLANTDISYDPQKIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKSLLGKDVARLPLAVVWLFSWPGVPCIY
YGDEVGVDGNNDPFCRKPFPWDPALQDTQLLALYQRMAKLRKAHQALRYGGCQVIYAEDNVVVFVRVYKQQRVLVAINRG
EACEVVIEDSPLLNVAGWTLQEGAGAFQDGVLTLPAISANVWSGR

Specific function: May play a role in regulating the intracellular level of maltotriose. Cleaves glucose from the reducing end of maltotriose and longer maltodextrins with a chain length of up to 7 glucose units [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=365, Percent_Identity=24.3835616438356, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1786604, Length=602, Percent_Identity=79.2358803986711, Blast_Score=1029, Evalue=0.0,
Organism=Escherichia coli, GI1790687, Length=244, Percent_Identity=27.0491803278689, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789995, Length=147, Percent_Identity=29.9319727891156, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322241, Length=258, Percent_Identity=25.5813953488372, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322021, Length=258, Percent_Identity=25.5813953488372, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6324416, Length=258, Percent_Identity=25.5813953488372, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6321726, Length=249, Percent_Identity=26.1044176706827, Blast_Score=84, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6322245, Length=255, Percent_Identity=25.0980392156863, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321731, Length=172, Percent_Identity=29.0697674418605, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319776, Length=172, Percent_Identity=29.0697674418605, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24586589, Length=421, Percent_Identity=25.8907363420428, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24586593, Length=578, Percent_Identity=23.0103806228374, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24586599, Length=560, Percent_Identity=23.2142857142857, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI45549022, Length=543, Percent_Identity=21.1786372007366, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24586591, Length=248, Percent_Identity=27.4193548387097, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24583749, Length=424, Percent_Identity=24.5283018867925, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583747, Length=424, Percent_Identity=24.5283018867925, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583745, Length=293, Percent_Identity=22.8668941979522, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24586597, Length=482, Percent_Identity=23.6514522821577, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24586587, Length=372, Percent_Identity=23.1182795698925, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221330053, Length=187, Percent_Identity=28.3422459893048, Blast_Score=73, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR004185
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783
- InterPro:   IPR014756
- InterPro:   IPR017069 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF02903 Alpha-amylase_N [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 68522; Mature: 68522

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKAWHLPVAPFIKVQQDRLFITLWLSGESLPQRITLRAEEDNEELSLPMQRLRQAPQPG
CCCCCCCCCCCCEEEECCEEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCC
VVAWRGEISLASGQPRRRYSFKLLWADHQRWFTPQGFTRFPPARLEQFAIDLPDAGPQWV
EEEEECEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHEEECCCCCHHHH
ADQVFYQIFPDRFARSAARDADQDAVYYHHAAGREIVRKAWDDPLTGEAGGSTFYGGDLD
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
GISEKLPYLKQLGVTALYLNPVFAAPSVHKYDTEDYRRVDPQFGGDAALLRLRHNTQRAG
CHHHHHHHHHHCCCEEEEECCHHCCCCCCCCCCHHHHCCCCCCCCCCEEEEEHHCHHHHH
MRMILDGVFNHTGDSHPWFDRHQQGSGGAGHDPDSPWRDWFTFSEEGQAHNWLGYASLPK
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCC
LDYRSTSLVNEIYAGEDSIVRHWLKAPWSMDGWRLDVVHMLGEGGGARNNLQHIAGITQA
CCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEEHEECCCCCCCCHHHHHHHHHHH
AKQAQPEAFVFGEHFGDARQWLQADAEDAAMNYRGFTFPIWGFLANTDISYDPQKIDAQT
HHHCCCCEEEECCHHHHHHHHHHCCCHHHHHCCCCCEEEHHHEEECCCCCCCHHHHHHHH
CMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKSLLGKDVARLPLAVVWLFSWPGVPCIY
HHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
YGDEVGVDGNNDPFCRKPFPWDPALQDTQLLALYQRMAKLRKAHQALRYGGCQVIYAEDN
ECCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
VVVFVRVYKQQRVLVAINRGEACEVVIEDSPLLNVAGWTLQEGAGAFQDGVLTLPAISAN
EEEEEEEECCCEEEEEECCCCEEEEEECCCCEEEECCCCHHCCCCCCCCCCEEECEEECC
VWSGR
CCCCC
>Mature Secondary Structure
MLKAWHLPVAPFIKVQQDRLFITLWLSGESLPQRITLRAEEDNEELSLPMQRLRQAPQPG
CCCCCCCCCCCCEEEECCEEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCC
VVAWRGEISLASGQPRRRYSFKLLWADHQRWFTPQGFTRFPPARLEQFAIDLPDAGPQWV
EEEEECEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHEEECCCCCHHHH
ADQVFYQIFPDRFARSAARDADQDAVYYHHAAGREIVRKAWDDPLTGEAGGSTFYGGDLD
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
GISEKLPYLKQLGVTALYLNPVFAAPSVHKYDTEDYRRVDPQFGGDAALLRLRHNTQRAG
CHHHHHHHHHHCCCEEEEECCHHCCCCCCCCCCHHHHCCCCCCCCCCEEEEEHHCHHHHH
MRMILDGVFNHTGDSHPWFDRHQQGSGGAGHDPDSPWRDWFTFSEEGQAHNWLGYASLPK
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCC
LDYRSTSLVNEIYAGEDSIVRHWLKAPWSMDGWRLDVVHMLGEGGGARNNLQHIAGITQA
CCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEEHEECCCCCCCCHHHHHHHHHHH
AKQAQPEAFVFGEHFGDARQWLQADAEDAAMNYRGFTFPIWGFLANTDISYDPQKIDAQT
HHHCCCCEEEECCHHHHHHHHHHCCCHHHHHCCCCCEEEHHHEEECCCCCCCHHHHHHHH
CMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKSLLGKDVARLPLAVVWLFSWPGVPCIY
HHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
YGDEVGVDGNNDPFCRKPFPWDPALQDTQLLALYQRMAKLRKAHQALRYGGCQVIYAEDN
ECCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
VVVFVRVYKQQRVLVAINRGEACEVVIEDSPLLNVAGWTLQEGAGAFQDGVLTLPAISAN
EEEEEEEECCCEEEEEECCCCEEEEEECCCCEEEECCCCHHCCCCCCCCCCEEECEEECC
VWSGR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1918057; 9278503; 1706703 [H]